Grik2 (glutamate ionotropic receptor kainate type subunit 2) - Rat Genome Database

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Gene: Grik2 (glutamate ionotropic receptor kainate type subunit 2) Chinchilla lanigera
Analyze
Symbol: Grik2
Name: glutamate ionotropic receptor kainate type subunit 2
RGD ID: 8944939
Description: ENCODES a protein that exhibits extracellularly glutamate-gated ion channel activity (ortholog); glutamate receptor activity (ortholog); glutamate-gated receptor activity (ortholog); INVOLVED IN behavioral fear response (ortholog); chemical synaptic transmission (ortholog); detection of cold stimulus involved in thermoception (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive intellectual developmental disorder 6 (ortholog); bipolar disorder (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); dendrite cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate receptor ionotropic, kainate 2; glutamate receptor, ionotropic, kainate 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541127,103,470 - 27,801,177 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541127,096,214 - 27,759,503 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Grik2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541127,103,470 - 27,801,177 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541127,096,214 - 27,759,503 (+)NCBIChiLan1.0ChiLan1.0
GRIK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386101,393,708 - 102,070,083 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6100,962,701 - 102,081,622 (+)EnsemblGRCh38hg38GRCh38
GRCh376101,841,584 - 102,517,958 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366101,953,675 - 102,623,474 (+)NCBINCBI36Build 36hg18NCBI36
Build 346101,953,674 - 102,623,474NCBI
Celera6102,490,982 - 103,163,448 (+)NCBICelera
Cytogenetic Map6q16.3NCBI
HuRef699,289,230 - 99,962,155 (+)NCBIHuRef
CHM1_16102,108,429 - 102,780,216 (+)NCBICHM1_1
T2T-CHM13v2.06102,567,441 - 103,245,122 (+)NCBIT2T-CHM13v2.0
Grik2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391048,969,776 - 49,666,523 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1048,970,929 - 49,664,862 (-)EnsemblGRCm39 Ensembl
GRCm381049,093,680 - 49,790,161 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1049,094,833 - 49,788,766 (-)EnsemblGRCm38mm10GRCm38
MGSCv371048,819,269 - 49,508,560 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361048,789,404 - 49,471,824 (-)NCBIMGSCv36mm8
Celera1049,961,395 - 50,650,295 (-)NCBICelera
Cytogenetic Map10B3NCBI
cM Map1024.87NCBI
Grik2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82053,717,564 - 54,415,283 (-)NCBIGRCr8
mRatBN7.22052,135,325 - 52,833,061 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2052,133,851 - 52,838,375 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2053,835,165 - 54,527,304 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02053,484,886 - 54,177,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02054,176,501 - 54,864,656 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02053,791,428 - 54,517,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2053,789,760 - 54,517,709 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02055,397,877 - 56,122,315 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42053,231,473 - 53,713,131 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12053,258,695 - 53,741,826 (-)NCBI
Celera2047,307,163 - 47,987,148 (+)NCBICelera
Cytogenetic Map20q13NCBI
GRIK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25120,926,005 - 122,109,168 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16118,808,051 - 119,995,774 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0698,720,430 - 99,903,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16103,106,776 - 103,784,640 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6103,334,707 - 103,783,092 (+)Ensemblpanpan1.1panPan2
GRIK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11258,932,754 - 59,991,305 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1259,355,017 - 59,990,408 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1258,685,896 - 59,760,448 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01259,766,364 - 60,827,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1260,189,211 - 60,826,416 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11259,112,703 - 60,183,136 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01258,954,426 - 60,016,937 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01259,195,178 - 60,257,015 (+)NCBIUU_Cfam_GSD_1.0
Grik2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494694,301,120 - 94,944,470 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366512,762,380 - 3,401,808 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366512,756,559 - 3,401,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl168,057,538 - 68,679,256 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1168,052,086 - 68,680,448 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2177,317,681 - 77,555,955 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11371,855,960 - 72,545,376 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1371,855,794 - 72,325,857 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604044,140,787 - 44,845,039 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grik2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248102,733,118 - 3,401,909 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248102,731,573 - 3,407,186 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005377815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005377816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013510935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013510936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01012184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01012198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBBH01106371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000016930   ⟹   ENSCLAP00000016766
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541127,103,470 - 27,757,913 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016931   ⟹   ENSCLAP00000016767
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541127,103,470 - 27,755,440 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016932   ⟹   ENSCLAP00000016768
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541127,103,470 - 27,753,804 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016933   ⟹   ENSCLAP00000016769
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541127,346,590 - 27,757,913 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000016934   ⟹   ENSCLAP00000016770
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541127,346,720 - 27,801,177 (+)Ensembl
RefSeq Acc Id: XM_005377815   ⟹   XP_005377872
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541127,096,214 - 27,759,503 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005377816   ⟹   XP_005377873
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541127,102,996 - 27,757,820 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510935   ⟹   XP_013366389
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541127,102,996 - 27,759,503 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510936   ⟹   XP_013366390
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541127,102,996 - 27,753,823 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005377872   ⟸   XM_005377815
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VJW2 (UniProtKB/TrEMBL),   A0A8C2VSA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005377873   ⟸   XM_005377816
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YQY3 (UniProtKB/TrEMBL),   A0A8C2VSA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366389   ⟸   XM_013510935
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VJW2 (UniProtKB/TrEMBL),   A0A8C2VSA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366390   ⟸   XM_013510936
- Peptide Label: isoform X3
- UniProtKB: A0A8C2YQX8 (UniProtKB/TrEMBL),   A0A8C2VSA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000016768   ⟸   ENSCLAT00000016932
RefSeq Acc Id: ENSCLAP00000016767   ⟸   ENSCLAT00000016931
RefSeq Acc Id: ENSCLAP00000016770   ⟸   ENSCLAT00000016934
RefSeq Acc Id: ENSCLAP00000016769   ⟸   ENSCLAT00000016933
RefSeq Acc Id: ENSCLAP00000016766   ⟸   ENSCLAT00000016930
Protein Domains
Ionotropic glutamate receptor C-terminal   Ionotropic glutamate receptor L-glutamate and


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011506 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016930 ENTREZGENE
  ENSCLAT00000016930.1 UniProtKB/TrEMBL
  ENSCLAT00000016931 ENTREZGENE
  ENSCLAT00000016931.1 UniProtKB/TrEMBL
  ENSCLAT00000016932 ENTREZGENE
  ENSCLAT00000016932.1 UniProtKB/TrEMBL
  ENSCLAT00000016933.1 UniProtKB/TrEMBL
  ENSCLAT00000016934.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  Glu/Gly-bd UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/TrEMBL
  Ionotropic_Glu_rcpt UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Grik2 ENTREZGENE
PANTHER GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/TrEMBL
  Lig_chan UniProtKB/TrEMBL
  Lig_chan-Glu_bd UniProtKB/TrEMBL
PRINTS NMDARECEPTOR UniProtKB/TrEMBL
SMART Lig_chan-Glu_bd UniProtKB/TrEMBL
  PBPe UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
  SSF53822 UniProtKB/TrEMBL
UniProt A0A8C2VJW2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VK79_CHILA UniProtKB/TrEMBL
  A0A8C2VSA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YQX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YQY3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Grik2  glutamate ionotropic receptor kainate type subunit 2    glutamate receptor, ionotropic, kainate 2  Symbol and/or name change 5135510 APPROVED