Asic3 (acid sensing ion channel subunit 3) - Rat Genome Database

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Gene: Asic3 (acid sensing ion channel subunit 3) Chinchilla lanigera
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Symbol: Asic3
Name: acid sensing ion channel subunit 3
RGD ID: 8944343
Description: ENCODES a protein that exhibits enterobactin transmembrane transporter activity (ortholog); ligand-gated sodium channel activity (ortholog); monoatomic cation channel activity (ortholog); INVOLVED IN detection of chemical stimulus involved in sensory perception (ortholog); detection of chemical stimulus involved in sensory perception of pain (ortholog); detection of mechanical stimulus involved in sensory perception (ortholog); ASSOCIATED WITH genetic disease (ortholog); Inflammation (ortholog); lethal congenital glycogen storage disease of heart (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acid sensing (proton gated) ion channel 3; acid-sensing (proton-gated) ion channel 3; acid-sensing ion channel 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,488,249 - 5,491,447 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Asic3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,488,249 - 5,491,447 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBIChiLan1.0ChiLan1.0
ASIC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,048,292 - 151,052,756 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7151,048,292 - 151,052,756 (+)EnsemblGRCh38hg38GRCh38
GRCh377150,745,379 - 150,749,843 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,376,885 - 150,380,774 (+)NCBINCBI36Build 36hg18NCBI36
Build 347150,183,609 - 150,187,488NCBI
Celera7145,302,914 - 145,307,152 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,557,715 - 144,562,179 (+)NCBIHuRef
CHM1_17150,753,727 - 150,758,191 (+)NCBICHM1_1
T2T-CHM13v2.07152,221,380 - 152,225,844 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,074,918 - 150,079,382 (+)NCBI
Asic3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,618,449 - 24,622,836 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,618,390 - 24,622,833 (+)EnsemblGRCm39 Ensembl
GRCm38524,413,451 - 24,417,840 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,413,392 - 24,417,835 (+)EnsemblGRCm38mm10GRCm38
MGSCv37523,919,269 - 23,923,652 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36523,923,516 - 23,927,899 (+)NCBIMGSCv36mm8
Celera521,363,200 - 21,367,641 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.72NCBI
Asic3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8411,652,946 - 11,657,415 (-)NCBIGRCr8
mRatBN7.2410,760,509 - 10,764,987 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,760,597 - 10,764,643 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,906,873 - 15,910,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0411,727,066 - 11,731,112 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0410,078,850 - 10,082,896 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.047,287,868 - 7,293,295 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl47,288,855 - 7,292,901 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.047,300,219 - 7,304,265 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.446,125,614 - 6,129,660 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.146,125,613 - 6,129,660 (-)NCBI
Celera46,375,165 - 6,379,211 (-)NCBICelera
Cytogenetic Map4q11NCBI
ASIC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,467,618 - 187,474,669 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,478,716 - 39,485,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07142,633,357 - 142,639,571 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17154,786,835 - 154,792,289 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,786,835 - 154,792,289 (+)Ensemblpanpan1.1panPan2
ASIC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,099,023 - 15,104,088 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,099,883 - 15,104,080 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,706,096 - 15,712,334 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01616,820,077 - 16,826,314 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1616,822,357 - 16,826,307 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,192,516 - 15,198,753 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01615,775,203 - 15,780,207 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01615,824,677 - 15,830,914 (+)NCBIUU_Cfam_GSD_1.0
Asic3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,424,673 - 6,428,461 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,474,995 - 6,478,711 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,473,305 - 6,478,756 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASIC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,172,471 - 6,180,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,172,410 - 6,180,440 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,542,445 - 6,547,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASIC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,226,940 - 119,234,626 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,230,796 - 119,234,696 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,198,711 - 15,205,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asic3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,567,541 - 5,570,851 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248005,567,516 - 5,571,292 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000001758   ⟹   ENSCLAP00000001715
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554915,488,249 - 5,491,447 (+)Ensembl
RefSeq Acc Id: XM_005404806   ⟹   XP_005404863
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005404807   ⟹   XP_005404864
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504583   ⟹   XP_013360037
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504584   ⟹   XP_013360038
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504585   ⟹   XP_013360039
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554915,487,788 - 5,491,562 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005404863   ⟸   XM_005404806
- Peptide Label: isoform X5
- UniProtKB: A0A8C2UKV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404864   ⟸   XM_005404807
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UKV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360037   ⟸   XM_013504583
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UKV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360038   ⟸   XM_013504584
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UKV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360039   ⟸   XM_013504585
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UKV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001715   ⟸   ENSCLAT00000001758


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001280 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001758 ENTREZGENE
  ENSCLAT00000001758.1 UniProtKB/TrEMBL
Gene3D-CATH Acid-sensing ion channels like domains UniProtKB/TrEMBL
  YojJ-like UniProtKB/TrEMBL
InterPro ENaC UniProtKB/TrEMBL
  ENaC_CS UniProtKB/TrEMBL
NCBI Gene Asic3 ENTREZGENE
PANTHER ACID-SENSING ION CHANNEL 3 UniProtKB/TrEMBL
  PTHR11690 UniProtKB/TrEMBL
Pfam ASC UniProtKB/TrEMBL
PRINTS AMINACHANNEL UniProtKB/TrEMBL
PROSITE ASC UniProtKB/TrEMBL
UniProt A0A8C2UKV9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Asic3  acid sensing ion channel subunit 3    acid sensing (proton gated) ion channel 3  Symbol and/or name change 5135510 APPROVED
2015-08-25 Asic3  acid sensing (proton gated) ion channel 3    acid-sensing (proton-gated) ion channel 3  Symbol and/or name change 5135510 APPROVED