Mycn (MYCN proto-oncogene, bHLH transcription factor)

Gene: Mycn (MYCN proto-oncogene, bHLH transcription factor) Chinchilla lanigera

Analyze

Symbol:

Mycn

Name:

MYCN proto-oncogene, bHLH transcription factor

RGD ID:

8943682

Description:

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); kinase binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN astrocyte differentiation (ortholog); autosome genomic imprinting (ortholog); branching morphogenesis of an epithelial tube (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Gallbladder (ortholog); amenorrhea (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	9,219,528 - 9,224,818 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955487	9,219,528 - 9,224,818 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenoid cystic carcinoma (ISO)

Agenesis of Gallbladder (ISO)

amenorrhea (ISO)

basal cell carcinoma (ISO)

Chromosome Aberrations (ISO)

double outlet right ventricle (ISO)

Experimental Neoplasms (ISO)

Feingold syndrome (ISO)

Feingold Syndrome 1 (ISO)

genetic disease (ISO)

glioblastoma (ISO)

Hyperplasia (ISO)

intellectual disability (ISO)

medulloblastoma (ISO)

Megalencephaly-Polydactyly Syndrome (ISO)

Necrosis (ISO)

Neoplastic Cell Transformation (ISO)

nephroblastoma (ISO)

neuroblastoma (ISO)

optic atrophy (ISO)

pancreatic adenocarcinoma (ISO)

schizophrenia (ISO)

T-cell acute lymphoblastic leukemia (ISO)

uterine cancer (ISO)

ventricular septal defect (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

astrocyte differentiation (ISO)

autosome genomic imprinting (ISO)

branching morphogenesis of an epithelial tube (ISO)

cartilage condensation (ISO)

cell population proliferation (ISO)

embryonic digit morphogenesis (ISO)

embryonic skeletal system morphogenesis (ISO)

epithelial cell proliferation (ISO)

lung development (ISO)

negative regulation of astrocyte differentiation (ISO)

negative regulation of gene expression (ISO)

negative regulation of reactive oxygen species metabolic process (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of epithelial cell proliferation (ISO)

positive regulation of gene expression (ISO)

positive regulation of mesenchymal cell proliferation (ISO)

positive regulation of programmed cell death (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of inner ear auditory receptor cell differentiation (ISO)

Cellular Component

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (ISO)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

kinase binding (ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Mycn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	9,219,528 - 9,224,818 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955487	9,219,528 - 9,224,818 (+)	NCBI	ChiLan1.0	ChiLan1.0

MYCN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	15,940,550 - 15,947,004 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	15,940,550 - 15,947,007 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	16,080,672 - 16,087,126 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	15,998,134 - 16,004,580 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	16,032,643 - 16,037,721	NCBI
Celera	2	15,998,381 - 16,004,827 (+)	NCBI		Celera
Cytogenetic Map	2	p24.3	NCBI
HuRef	2	15,934,021 - 15,938,396 (+)	NCBI		HuRef
CHM1_1	2	16,010,469 - 16,016,915 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	15,972,182 - 15,978,635 (+)	NCBI		T2T-CHM13v2.0

Mycn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	12,986,094 - 12,991,837 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	12,986,094 - 12,991,915 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	12,936,093 - 12,941,836 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	12,936,093 - 12,941,914 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	12,942,899 - 12,948,642 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	12,962,079 - 12,967,694 (-)	NCBI		MGSCv36	mm8
Celera	12	13,282,496 - 13,288,240 (-)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	6.14	NCBI

Mycn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	41,446,683 - 41,452,584 (-)	NCBI		GRCr8
mRatBN7.2	6	35,717,764 - 35,723,590 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	35,717,764 - 35,723,590 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	36,030,195 - 36,036,011 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	36,344,835 - 36,350,651 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	35,812,708 - 35,818,534 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	38,222,554 - 38,228,419 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	38,222,555 - 38,228,379 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	51,348,169 - 51,354,719 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	36,508,262 - 36,514,071 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	35,082,308 - 35,088,132 (-)	NCBI		Celera
Cytogenetic Map	6	q15	NCBI

MYCN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	110,580,807 - 110,585,956 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	110,584,779 - 110,591,313 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	15,925,130 - 15,931,605 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	16,058,298 - 16,064,547 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

MYCN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	11,720,857 - 11,724,308 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	11,663,228 - 11,669,338 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	11,848,344 - 11,854,451 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	11,848,002 - 11,854,448 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	11,707,661 - 11,713,769 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	11,718,338 - 11,724,418 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	11,742,671 - 11,748,783 (+)	NCBI		UU_Cfam_GSD_1.0

Mycn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	56,215,359 - 56,221,421 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	14,618,060 - 14,624,315 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	14,618,176 - 14,624,201 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYCN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	121,543,109 - 121,549,046 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	121,543,201 - 121,549,678 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	129,821,890 - 129,827,921 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYCN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	91,685,376 - 91,692,091 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	20,532,406 - 20,539,075 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mycn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624865	780,163 - 785,776 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005404445	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005404446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01059455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01101398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000010135 ⟹ ENSCLAP00000010005

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955487	9,219,528 - 9,224,818 (+)	Ensembl

RefSeq Acc Id:

XM_005404445 ⟹ XP_005404502

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955487	9,219,528 - 9,224,818 (+)	NCBI

Sequence:

show sequence

CTGCCTCGCCCCCTCCCCTGGCCTGCGCCACAGCCCCTTCTCTCCCCGCCTCCCGGGTGTGTCA
GATTTTTCAGTTAATAATATCCCCCGAGCTTCAAAGCGCAGTCAGTGACAGTCATCTGTCTGTG
CGGGGGACTTCTGGGACCGTGTCGGAGCTGAGCGGGCGCAAGGCGCGCGCAGTGCAGCGCACGG
ACCGTGGACTCCGAGACCCCGAGCGGCCCGAGAGCAGGTCTGGGGAGCGACGGAGTCCGCGGGT
GCAGTGGGTGCCGCCGTCCGCCGCCCGGCTCCGCCCCGCACGACATGCCGGGCATGATCCGCAA
GAACCCGGACCTCGAGTTCGACTCGCTGCAGCCCTGCTTCCTCCCGGACGAGGATGACTTCTAC
TTCGGCGGCCCCGACTCCACGCCGCCGGGAGAGGACATCTGGAAGAAGTTCCAGCTGCTGCCCA
CGCCGCCACTGTCGCCTAGCCGTGCGTTCCCGGAGCCCTCGGACTGGGCCACCGAGATGCTGCT
GTGCGAGCCCGGCCTGTGGGGCGACCCGGCCGAGGAGGAGGCGTTCGGTTTGGGGGAGCTGAGC
CGCCTCACCCCGAACCCCGTCATCCTGCAGGATTGCATGTGGAGCGGCTTCTCCGCGCGCGAGA
AGCTGGAGCGTGCGGTGAGCGAGAAGCTGCAGCTCGGCCGCGCGCCCCTGGCCCCTGCGCCCTC
CGCCCCGGGACCCCCACGAGAGCACCCCGGGGGCGCCGCCGACTGCGTGGACCCCGCCGCGGTC
TTCCCGTTCCGGGAGACCCCCCGCGAGCCTGCTCCTGCCTCCCCGGCCGGGGTCCCCACGCCAG
GCGCAGCCCCGGTAGTCGCCGGGGTCCCCTCAGTAGCCGCAGCTCCGGGGGCCGCTTCCCCACT
CTCTGAAGACCGCACGGACTCCACGGCGACGCCAAGCACCTCCGGCGAGGACACACTGAGCGAC
TCGGATGAGGAGGACGAGGAGGAGGAGGAGGAGGAGGAGGAGATTGATGTGGTGACCGTGGAGA
AGCGGCGGTGCTCCTCGGGTGGCAAGGCGGTCACCACCTTCACCATCACCGTGCGCCCCAAGGG
TGCGGGCCGCCCGGGCCCCTGTGAGCTGCCTCTCAAGCGCTGCGCCCCCGTCCACCAGCAGCAC
AACTACGCGGCGCCCTCCCCCTTTGAGGAGATGGAGGAGCCCCTGCAGAAGAGGCCCAAGGGCG
AGGCGGTGCTCCGGCCCCTCAAGGGAGTGGCCCCCGCCGCCAAGCCCAAGAGCGCGAGCCCGCG
GCACTCGGACTCGGAGGACAGCGAGCGCCGGCGCAACCACAACATCTTGGAGCGGCAGCGCCGC
AACGACCTGCGCTCCAGCTTCCTGACGCTCAGGGACCACGTGCCCGAGCTGGTGCGCAATGAGA
AGGCCGCCAAGGTGGTCATCCTGAAGAAGGCCACGGAGTATGTGCGCGCCCTCCAGGCCGCCGA
GCAGCAGCTGCTGCTGGAGAAGGAGGCCTTGCAGGCCCGGCGGCGGCAGCTGCTCAAGAGTGTG
GAGCTCTCCAGGACTTGCTAGGCGTCCCTCGACGAGCGGCCGCAGATGGACGCTCACTGCCACG
TTTTGCACATTTGGATTTTTATTTTTAAACGTTGTGTTGACATTAAGAATGTTGGTTTACTTTC
TCCAATCGGCCTCCTTTCGTGTTTGGATCTGGGTGGGGGCAGGACCTGTGGGGTTCTGTGGGAT
GTCTAGGAGCTCTCCCAGGATGCTGGGTGGCTCCGGGCCTCCTCTGCTGCCCACCCCATGGCAG
CTGCGACGTCTTGACTGTTGGGAGCCACAGCCTGGGACACCGTGGTTCCTCTCCTTTTTACAAT
GGTGCTTAAACTCCAGCCGTGTGCGCCCCGGGGACGTCCGTGTAAATACTGTGGACACCGCCTT
GTCCTGGTGAGGAGGTGGCCGTGGCCCGGCTCTGGCAAGTGCTGTAAGGATACCTCAATGTTTG
AGGGGCATGGTTTGTATACGAATCTATTGTTAATCCCGGTTCTGTGCTGTACTAATTCCTACAC
TGCCTGTATACTTTAGGATGACGCTGATATATAACTACATTTGATACTTATATTTTCGTATGAA
AATGAGTTGTGAAAGTTTTGAGTAGATATTACTTTATCACTTTTTGAACTAAGAAAATTTTGTA
AAGAAATTTACTATATATATGCCTTTTTCCTAGCCTGTTTTTGTTTTTTCCCTCTCTTAATGTA
TTTGTTCATGTTTGGTGCATAGAACTGGGAAATGCAAAGTTCTGTGTTGAATTTCTTCAAAATG
TATATATTTAGTGCTGCATTTATAGCACTTTGAAATACCTCATGTTTATGAAAATAAATAGCAA
TTAAA

hide sequence

RefSeq Acc Id:

XM_005404446 ⟹ XP_005404503

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955487	9,219,529 - 9,224,818 (+)	NCBI

Sequence:

show sequence

TGCCTCGCCCCCTCCCCTGGCCTGCGCCACAGCCCCTTCTCTCCCCGCCTCCCGGGTGTGTCAG
ATTTTTCAGTTAATAATATCCCCCGAGCTTCAAAGCGCAGTCAGTGACAGTCATCTGTCTGTGC
GGGGGACTTCTGGGACCGTGTCGGAGCTGAGCGGGCGCAAGGCGCGCGCAGTGCAGCGCACGGA
CCGTGGACTCCGAGACCCCGAGCGGCCCGAGAGGTCTGGGGAGCGACGGAGTCCGCGGGTGCAG
TGGGTGCCGCCGTCCGCCGCCCGGCTCCGCCCCGCACGACATGCCGGGCATGATCCGCAAGAAC
CCGGACCTCGAGTTCGACTCGCTGCAGCCCTGCTTCCTCCCGGACGAGGATGACTTCTACTTCG
GCGGCCCCGACTCCACGCCGCCGGGAGAGGACATCTGGAAGAAGTTCCAGCTGCTGCCCACGCC
GCCACTGTCGCCTAGCCGTGCGTTCCCGGAGCCCTCGGACTGGGCCACCGAGATGCTGCTGTGC
GAGCCCGGCCTGTGGGGCGACCCGGCCGAGGAGGAGGCGTTCGGTTTGGGGGAGCTGAGCCGCC
TCACCCCGAACCCCGTCATCCTGCAGGATTGCATGTGGAGCGGCTTCTCCGCGCGCGAGAAGCT
GGAGCGTGCGGTGAGCGAGAAGCTGCAGCTCGGCCGCGCGCCCCTGGCCCCTGCGCCCTCCGCC
CCGGGACCCCCACGAGAGCACCCCGGGGGCGCCGCCGACTGCGTGGACCCCGCCGCGGTCTTCC
CGTTCCGGGAGACCCCCCGCGAGCCTGCTCCTGCCTCCCCGGCCGGGGTCCCCACGCCAGGCGC
AGCCCCGGTAGTCGCCGGGGTCCCCTCAGTAGCCGCAGCTCCGGGGGCCGCTTCCCCACTCTCT
GAAGACCGCACGGACTCCACGGCGACGCCAAGCACCTCCGGCGAGGACACACTGAGCGACTCGG
ATGAGGAGGACGAGGAGGAGGAGGAGGAGGAGGAGGAGATTGATGTGGTGACCGTGGAGAAGCG
GCGGTGCTCCTCGGGTGGCAAGGCGGTCACCACCTTCACCATCACCGTGCGCCCCAAGGGTGCG
GGCCGCCCGGGCCCCTGTGAGCTGCCTCTCAAGCGCTGCGCCCCCGTCCACCAGCAGCACAACT
ACGCGGCGCCCTCCCCCTTTGAGGAGATGGAGGAGCCCCTGCAGAAGAGGCCCAAGGGCGAGGC
GGTGCTCCGGCCCCTCAAGGGAGTGGCCCCCGCCGCCAAGCCCAAGAGCGCGAGCCCGCGGCAC
TCGGACTCGGAGGACAGCGAGCGCCGGCGCAACCACAACATCTTGGAGCGGCAGCGCCGCAACG
ACCTGCGCTCCAGCTTCCTGACGCTCAGGGACCACGTGCCCGAGCTGGTGCGCAATGAGAAGGC
CGCCAAGGTGGTCATCCTGAAGAAGGCCACGGAGTATGTGCGCGCCCTCCAGGCCGCCGAGCAG
CAGCTGCTGCTGGAGAAGGAGGCCTTGCAGGCCCGGCGGCGGCAGCTGCTCAAGAGTGTGGAGC
TCTCCAGGACTTGCTAGGCGTCCCTCGACGAGCGGCCGCAGATGGACGCTCACTGCCACGTTTT
GCACATTTGGATTTTTATTTTTAAACGTTGTGTTGACATTAAGAATGTTGGTTTACTTTCTCCA
ATCGGCCTCCTTTCGTGTTTGGATCTGGGTGGGGGCAGGACCTGTGGGGTTCTGTGGGATGTCT
AGGAGCTCTCCCAGGATGCTGGGTGGCTCCGGGCCTCCTCTGCTGCCCACCCCATGGCAGCTGC
GACGTCTTGACTGTTGGGAGCCACAGCCTGGGACACCGTGGTTCCTCTCCTTTTTACAATGGTG
CTTAAACTCCAGCCGTGTGCGCCCCGGGGACGTCCGTGTAAATACTGTGGACACCGCCTTGTCC
TGGTGAGGAGGTGGCCGTGGCCCGGCTCTGGCAAGTGCTGTAAGGATACCTCAATGTTTGAGGG
GCATGGTTTGTATACGAATCTATTGTTAATCCCGGTTCTGTGCTGTACTAATTCCTACACTGCC
TGTATACTTTAGGATGACGCTGATATATAACTACATTTGATACTTATATTTTCGTATGAAAATG
AGTTGTGAAAGTTTTGAGTAGATATTACTTTATCACTTTTTGAACTAAGAAAATTTTGTAAAGA
AATTTACTATATATATGCCTTTTTCCTAGCCTGTTTTTGTTTTTTCCCTCTCTTAATGTATTTG
TTCATGTTTGGTGCATAGAACTGGGAAATGCAAAGTTCTGTGTTGAATTTCTTCAAAATGTATA
TATTTAGTGCTGCATTTATAGCACTTTGAAATACCTCATGTTTATGAAAATAAATAGCAATTAA
A

hide sequence

Protein Sequences


Protein RefSeqs	XP_005404502	(Get FASTA)	NCBI Sequence Viewer
	XP_005404503	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010005
	ENSCLAP00000010005.1

RefSeq Acc Id:

XP_005404502 ⟸ XM_005404445

- UniProtKB:

A0A8C2V436 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPGMIRKNPDLEFDSLQPCFLPDEDDFYFGGPDSTPPGEDIWKKFQLLPTPPLSPSRAFPEPSD
WATEMLLCEPGLWGDPAEEEAFGLGELSRLTPNPVILQDCMWSGFSAREKLERAVSEKLQLGRA
PLAPAPSAPGPPREHPGGAADCVDPAAVFPFRETPREPAPASPAGVPTPGAAPVVAGVPSVAAA
PGAASPLSEDRTDSTATPSTSGEDTLSDSDEEDEEEEEEEEEIDVVTVEKRRCSSGGKAVTTFT
ITVRPKGAGRPGPCELPLKRCAPVHQQHNYAAPSPFEEMEEPLQKRPKGEAVLRPLKGVAPAAK
PKSASPRHSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVRNEKAAKVVILKKATEYV
RALQAAEQQLLLEKEALQARRRQLLKSVELSRTC

hide sequence

RefSeq Acc Id:

XP_005404503 ⟸ XM_005404446

- UniProtKB:

A0A8C2V436 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPGMIRKNPDLEFDSLQPCFLPDEDDFYFGGPDSTPPGEDIWKKFQLLPTPPLSPSRAFPEPSD
WATEMLLCEPGLWGDPAEEEAFGLGELSRLTPNPVILQDCMWSGFSAREKLERAVSEKLQLGRA
PLAPAPSAPGPPREHPGGAADCVDPAAVFPFRETPREPAPASPAGVPTPGAAPVVAGVPSVAAA
PGAASPLSEDRTDSTATPSTSGEDTLSDSDEEDEEEEEEEEEIDVVTVEKRRCSSGGKAVTTFT
ITVRPKGAGRPGPCELPLKRCAPVHQQHNYAAPSPFEEMEEPLQKRPKGEAVLRPLKGVAPAAK
PKSASPRHSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVRNEKAAKVVILKKATEYV
RALQAAEQQLLLEKEALQARRRQLLKSVELSRTC

hide sequence

RefSeq Acc Id:

ENSCLAP00000010005 ⟸ ENSCLAT00000010135

Protein Domains

bHLH

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000006932	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000010135	ENTREZGENE
	ENSCLAT00000010135.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
	Tscrpt_reg_Myc	UniProtKB/TrEMBL
	Tscrpt_reg_Myc_N	UniProtKB/TrEMBL
NCBI Gene	Mycn	ENTREZGENE
PANTHER	MYC PROTO-ONCOGENE	UniProtKB/TrEMBL
	N-MYC PROTO-ONCOGENE PROTEIN	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
	Myc_N	UniProtKB/TrEMBL
PIRSF	Myc_protein	UniProtKB/TrEMBL
PRINTS	LEUZIPPRMYC	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/TrEMBL
UniProt	A0A8C2V436	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-08	Mycn	MYCN proto-oncogene, bHLH transcription factor		v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM