Ippk (inositol-pentakisphosphate 2-kinase) - Rat Genome Database

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Gene: Ippk (inositol-pentakisphosphate 2-kinase) Chinchilla lanigera
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Symbol: Ippk
Name: inositol-pentakisphosphate 2-kinase
RGD ID: 8942528
Description: ENCODES a protein that exhibits inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH hereditary sensory and autonomic neuropathy type 1 (ortholog); hereditary sensory neuropathy (ortholog); spinal muscular atrophy with lower extremity predominant 2A (ortholog); FOUND IN nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inositol 1,3,4,5,6-pentakisphosphate 2-kinase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555155,170,164 - 5,219,130 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555155,170,164 - 5,219,130 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ippk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555155,170,164 - 5,219,130 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555155,170,164 - 5,219,130 (+)NCBIChiLan1.0ChiLan1.0
IPPK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38992,613,183 - 92,670,131 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl992,613,183 - 92,670,131 (-)EnsemblGRCh38hg38GRCh38
GRCh37995,375,465 - 95,432,413 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36994,415,287 - 94,472,368 (-)NCBINCBI36Build 36hg18NCBI36
Build 34992,455,020 - 92,512,102NCBI
Celera965,817,524 - 65,874,595 (-)NCBICelera
Cytogenetic Map9q22.31NCBI
HuRef965,053,819 - 65,110,851 (-)NCBIHuRef
CHM1_1995,521,868 - 95,578,933 (-)NCBICHM1_1
T2T-CHM13v2.09104,779,754 - 104,836,695 (-)NCBIT2T-CHM13v2.0
Ippk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391349,574,673 - 49,618,050 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1349,574,725 - 49,618,049 (+)EnsemblGRCm39 Ensembl
GRCm381349,421,198 - 49,464,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1349,421,249 - 49,464,573 (+)EnsemblGRCm38mm10GRCm38
MGSCv371349,516,680 - 49,558,359 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361349,433,248 - 49,474,927 (+)NCBIMGSCv36mm8
Celera1350,510,826 - 50,552,610 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1325.25NCBI
Ippk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81715,396,691 - 15,441,648 (-)NCBIGRCr8
mRatBN7.21715,190,191 - 15,235,203 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1715,190,265 - 15,229,541 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1715,078,608 - 15,116,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01716,683,663 - 16,721,566 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01715,005,394 - 15,043,299 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01715,604,148 - 15,643,312 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,604,145 - 15,643,489 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01717,662,547 - 17,701,642 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41721,147,481 - 21,185,525 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11721,147,480 - 21,185,525 (-)NCBI
Celera1714,922,371 - 14,960,214 (-)NCBICelera
Cytogenetic Map17p14NCBI
IPPK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21146,758,170 - 46,814,213 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1946,760,560 - 46,816,599 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0963,737,324 - 63,793,348 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1991,808,757 - 91,864,773 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl991,808,757 - 91,864,773 (-)Ensemblpanpan1.1panPan2
IPPK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1198,760,104 - 98,800,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl198,759,976 - 98,800,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,153,945 - 99,194,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0199,376,891 - 99,417,695 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl199,376,666 - 99,417,687 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1198,989,996 - 99,030,788 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0198,725,536 - 98,766,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0199,481,198 - 99,521,965 (+)NCBIUU_Cfam_GSD_1.0
Ippk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049447,984,122 - 8,037,682 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364872,198,973 - 2,254,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364872,200,588 - 2,254,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPPK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl342,308,005 - 42,368,118 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1342,308,001 - 42,368,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2343,492,552 - 43,500,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IPPK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112103,122,293 - 103,184,453 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12103,123,557 - 103,184,174 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603891,394,542 - 91,456,260 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ippk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248683,722,800 - 3,779,747 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248683,722,713 - 3,781,639 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000004376   ⟹   ENSCLAP00000004294
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555155,170,164 - 5,219,130 (+)Ensembl
RefSeq Acc Id: XM_005408913   ⟹   XP_005408970
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555155,170,164 - 5,219,130 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005408914   ⟹   XP_005408971
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555155,170,164 - 5,219,130 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013506872   ⟹   XP_013362326
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555155,170,302 - 5,219,130 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005408970 (Get FASTA)   NCBI Sequence Viewer  
  XP_005408971 (Get FASTA)   NCBI Sequence Viewer  
  XP_013362326 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004294
  ENSCLAP00000004294.1
RefSeq Acc Id: XP_005408971   ⟸   XM_005408914
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YJZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005408970   ⟸   XM_005408913
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013362326   ⟸   XM_013506872
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000004294   ⟸   ENSCLAT00000004376


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003054 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004376 ENTREZGENE
  ENSCLAT00000004376.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.200.110 UniProtKB/TrEMBL
InterPro Ins_P5_2-kin UniProtKB/TrEMBL
  IP5_2-K_N_lobe UniProtKB/TrEMBL
NCBI Gene Ippk ENTREZGENE
PANTHER INOSITOL-PENTAKISPHOSPHATE 2-KINASE UniProtKB/TrEMBL
  PTHR14456 UniProtKB/TrEMBL
Pfam Ins_P5_2-kin UniProtKB/TrEMBL
UniProt A0A8C2YJZ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ippk  inositol-pentakisphosphate 2-kinase    inositol 1,3,4,5,6-pentakisphosphate 2-kinase  Symbol and/or name change 5135510 APPROVED