Cdh2 (cadherin 2) - Rat Genome Database

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Gene: Cdh2 (cadherin 2) Chinchilla lanigera
Analyze
Symbol: Cdh2
Name: cadherin 2
RGD ID: 8939608
Description: ENCODES a protein that exhibits alpha-catenin binding (ortholog); beta-catenin binding (ortholog); calcium ion binding (ortholog); INVOLVED IN blood vessel morphogenesis (ortholog); brain morphogenesis (ortholog); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (ortholog); PARTICIPATES IN cadherin mediated signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); AGENESIS OF CORPUS CALLOSUM, CARDIAC, OCULAR, AND GENITAL SYNDROME (ortholog); Animal Disease Models (ortholog); FOUND IN adherens junction (ortholog); apical plasma membrane (ortholog); apicolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cadherin 2, type 1, N-cadherin (neuronal); cadherin-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540215,831,110 - 16,049,890 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540215,829,895 - 16,049,874 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
blood vessel morphogenesis  (ISO)
brain morphogenesis  (ISO)
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
cell adhesion  (ISO)
cell migration  (ISO)
cell-cell adhesion  (ISO)
cell-cell adhesion mediated by cadherin  (ISO)
cell-cell junction assembly  (ISO)
cerebral cortex development  (ISO)
glial cell differentiation  (ISO)
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
homeostasis of number of cells  (ISO)
homophilic cell adhesion via plasma membrane adhesion molecules  (ISO)
mesenchymal cell migration  (ISO)
modulation of chemical synaptic transmission  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
neural crest cell development  (ISO)
neuroepithelial cell differentiation  (ISO)
neuroligin clustering involved in postsynaptic membrane assembly  (ISO)
neuronal stem cell population maintenance  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of synaptic vesicle clustering  (ISO)
protein localization to plasma membrane  (ISO)
radial glial cell differentiation  (ISO)
regulation of axonogenesis  (ISO)
regulation of myelination  (ISO)
regulation of oligodendrocyte progenitor proliferation  (ISO)
regulation of postsynaptic density protein 95 clustering  (ISO)
regulation of protein localization  (ISO)
regulation of Rho protein signal transduction  (ISO)
regulation of synaptic transmission, glutamatergic  (ISO)
striated muscle cell differentiation  (ISO)
synapse assembly  (ISO)
telencephalon development  (ISO)
type B pancreatic cell development  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Cdh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540215,831,110 - 16,049,890 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540215,829,895 - 16,049,874 (-)NCBIChiLan1.0ChiLan1.0
CDH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1827,950,966 - 28,177,130 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1827,932,879 - 28,177,946 (-)EnsemblGRCh38hg38GRCh38
GRCh381827,932,878 - 28,177,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371825,530,930 - 25,757,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361823,784,933 - 24,011,189 (-)NCBINCBI36hg18NCBI36
Build 341823,784,933 - 24,011,189NCBI
Celera1822,342,317 - 22,568,868 (-)NCBI
Cytogenetic Map18q12.1NCBI
HuRef1822,383,072 - 22,579,896 (-)NCBIHuRef
CHM1_11825,458,395 - 25,684,846 (-)NCBICHM1_1
Cdh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391816,721,934 - 16,942,303 (-)NCBIGRCm39mm39
GRCm39 Ensembl1816,721,934 - 16,942,303 (-)Ensembl
GRCm381816,588,877 - 16,809,246 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1816,588,877 - 16,809,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv371816,747,386 - 16,967,558 (-)NCBIGRCm37mm9NCBIm37
MGSCv361816,732,027 - 16,952,264 (-)NCBImm8
Celera1817,099,283 - 17,328,154 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map1810.1NCBI
Cdh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2187,776,704 - 7,990,934 (-)NCBI
Rnor_6.0 Ensembl188,146,971 - 8,360,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0188,146,971 - 8,366,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0187,997,533 - 8,218,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,048,920 - 8,267,974 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1188,048,919 - 8,268,462 (-)NCBI
Celera187,938,006 - 8,155,134 (-)NCBICelera
Cytogenetic Map18p13NCBI
CDH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11824,812,019 - 25,008,249 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1824,812,019 - 25,008,325 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01821,210,001 - 21,435,919 (-)NCBIMhudiblu_PPA_v0panPan3
CDH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1760,736,760 - 60,950,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl760,736,760 - 60,951,034 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha760,142,523 - 60,355,795 (+)NCBI
ROS_Cfam_1.0760,754,899 - 60,968,628 (+)NCBI
UMICH_Zoey_3.1760,431,048 - 60,644,193 (+)NCBI
UNSW_CanFamBas_1.0760,442,612 - 60,655,854 (+)NCBI
UU_Cfam_GSD_1.0760,744,933 - 60,958,801 (+)NCBI
Cdh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494456,749,166 - 56,930,675 (+)NCBI
SpeTri2.0NW_0049365506,885,484 - 7,067,001 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6112,396,721 - 112,628,432 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16112,396,713 - 112,629,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26105,317,507 - 105,518,900 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDH2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11852,426,381 - 52,652,986 (+)NCBI
ChlSab1.1 Ensembl1852,426,077 - 52,654,828 (+)Ensembl
Cdh2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247704,333,643 - 4,540,817 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022377   ⟹   ENSCLAP00000022172
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540215,831,110 - 16,049,890 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000022378   ⟹   ENSCLAP00000022173
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540215,831,110 - 15,908,196 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000022379   ⟹   ENSCLAP00000022174
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540215,831,110 - 15,888,621 (-)Ensembl
RefSeq Acc Id: XM_005372737   ⟹   XP_005372794
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540215,829,895 - 16,049,874 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005372794 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005372794   ⟸   XM_005372737
- Sequence:
RefSeq Acc Id: ENSCLAP00000022172   ⟸   ENSCLAT00000022377
RefSeq Acc Id: ENSCLAP00000022174   ⟸   ENSCLAT00000022379
RefSeq Acc Id: ENSCLAP00000022173   ⟸   ENSCLAT00000022378


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015205 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000022172 ENTREZGENE
Ensembl Transcript ENSCLAT00000022377 ENTREZGENE
NCBI Gene Cdh2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cdh2  cadherin 2    cadherin 2, type 1, N-cadherin (neuronal)  Symbol and/or name change 5135510 APPROVED