Adamts12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) - Rat Genome Database

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Gene: Adamts12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) Chinchilla lanigera
Analyze
Symbol: Adamts12
Name: ADAM metallopeptidase with thrombospondin type 1 motif 12
RGD ID: 8937886
Description: ENCODES a protein that exhibits metalloendopeptidase activity (ortholog); INVOLVED IN cell migration (ortholog); cell-matrix adhesion (ortholog); cellular response to BMP stimulus (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); Stroke (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM metallopeptidase with thrombospondin type 1 motif, 12
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542619,150,343 - 19,471,534 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542619,146,288 - 19,471,880 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Adamts12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542619,150,343 - 19,471,534 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542619,146,288 - 19,471,880 (-)NCBIChiLan1.0ChiLan1.0
ADAMTS12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38533,523,535 - 33,891,990 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl533,523,535 - 33,892,019 (-)EnsemblGRCh38hg38GRCh38
GRCh37533,523,640 - 33,892,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36533,563,043 - 33,927,881 (-)NCBINCBI36hg18NCBI36
Build 34533,563,042 - 33,927,881NCBI
Celera533,408,303 - 33,780,613 (-)NCBI
Cytogenetic Map5p13.3-p13.2NCBI
HuRef533,495,595 - 33,870,040 (-)NCBIHuRef
CHM1_1533,528,883 - 33,893,746 (-)NCBICHM1_1
T2T-CHM13v2.0533,638,143 - 34,013,900 (-)NCBI
Adamts12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391511,064,781 - 11,349,321 (+)NCBIGRCm39mm39
GRCm39 Ensembl1511,064,876 - 11,349,317 (+)Ensembl
GRCm381511,064,773 - 11,349,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1511,064,790 - 11,349,231 (+)EnsemblGRCm38mm10GRCm38
MGSCv371510,994,545 - 11,276,622 (+)NCBIGRCm37mm9NCBIm37
MGSCv361511,009,756 - 11,290,402 (+)NCBImm8
Celera1510,855,060 - 11,130,577 (+)NCBICelera
Cytogenetic Map15A1NCBI
Adamts12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2260,032,873 - 60,327,629 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl260,032,873 - 60,327,629 (+)Ensembl
Rnor_6.0261,039,072 - 61,340,687 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl261,039,053 - 61,340,697 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0283,352,798 - 83,650,251 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4260,427,824 - 60,717,617 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1260,349,718 - 60,645,857 (+)NCBI
Celera258,357,418 - 58,652,079 (-)NCBICelera
Cytogenetic Map2q16NCBI
ADAMTS12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1581,828,264 - 82,203,497 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl581,827,560 - 82,199,840 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0576,442,053 - 76,818,726 (+)NCBIMhudiblu_PPA_v0panPan3
ADAMTS12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1473,887,959 - 74,188,909 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl473,887,924 - 74,001,984 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha473,503,678 - 73,767,544 (+)NCBI
Dog10K_Boxer_Tasha473,777,238 - 73,812,152 (+)NCBI
ROS_Cfam_1.0474,394,459 - 74,697,683 (+)NCBI
ROS_Cfam_1.0 Ensembl474,379,341 - 74,696,853 (+)Ensembl
UMICH_Zoey_3.1474,140,285 - 74,398,310 (+)NCBI
UNSW_CanFamBas_1.0474,264,326 - 74,571,548 (+)NCBI
UU_Cfam_GSD_1.0474,798,493 - 75,101,600 (+)NCBI
Adamts12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213223,889,032 - 224,191,694 (-)NCBI
SpeTri2.0NW_0049365187,180,262 - 7,483,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1619,547,011 - 19,920,513 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11619,547,003 - 19,920,780 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21620,237,769 - 20,454,645 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1432,757,699 - 33,129,116 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl432,757,684 - 33,129,059 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607123,035,326 - 23,424,713 (-)NCBIVero_WHO_p1.0
Adamts12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475920,898,761 - 21,088,838 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475920,749,548 - 21,092,816 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009873   ⟹   ENSCLAP00000009744
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542619,150,343 - 19,471,534 (-)Ensembl
RefSeq Acc Id: XM_005386164   ⟹   XP_005386221
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542619,146,288 - 19,471,880 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386221 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005386221   ⟸   XM_005386164
- Sequence:
RefSeq Acc Id: ENSCLAP00000009744   ⟸   ENSCLAT00000009873
Protein Domains
Peptidase M12B   PLAC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006753 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000009744 ENTREZGENE
  ENSCLAP00000009744.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009873 ENTREZGENE
  ENSCLAT00000009873.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_CR_2 UniProtKB/TrEMBL
  ADAMTS_CR_3 UniProtKB/TrEMBL
  ADAMTS_spacer1 UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene Adamts12 ENTREZGENE
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_CR_3 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  PLAC UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART TSP1 UniProtKB/TrEMBL
Superfamily-SCOP SSF82895 UniProtKB/TrEMBL
UniProt A0A8C2YML2_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Adamts12  ADAM metallopeptidase with thrombospondin type 1 motif 12    ADAM metallopeptidase with thrombospondin type 1 motif, 12  Symbol and/or name change 5135510 APPROVED