Abcg2 (ATP binding cassette subfamily G member 2 (JR blood group)) - Rat Genome Database

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Gene: Abcg2 (ATP binding cassette subfamily G member 2 (JR blood group)) Chinchilla lanigera
Analyze
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2 (JR blood group)
RGD ID: 8935489
Description: ENCODES a protein that exhibits ABC-type xenobiotic transporter activity (ortholog); amide transmembrane transporter activity (ortholog); ATPase-coupled transmembrane transporter activity (ortholog); INVOLVED IN biotin transport (ortholog); cellular detoxification (ortholog); cellular response to dexamethasone stimulus (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; erlotinib pharmacodynamics pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute megakaryocytic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN apical plasma membrane (ortholog); brush border membrane (ortholog); external side of apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette sub-family G member 2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547412,365,903 - 12,408,715 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Abcg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547412,365,903 - 12,408,715 (+)NCBIChiLan1.0ChiLan1.0
ABCG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38488,090,264 - 88,231,626 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl488,090,150 - 88,231,628 (-)EnsemblGRCh38hg38GRCh38
GRCh37489,011,416 - 89,152,778 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36489,230,440 - 89,299,035 (-)NCBINCBI36Build 36hg18NCBI36
Build 34489,370,018 - 89,436,901NCBI
Celera486,303,350 - 86,371,627 (-)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef484,757,887 - 84,903,974 (-)NCBIHuRef
CHM1_1488,988,243 - 89,128,985 (-)NCBICHM1_1
T2T-CHM13v2.0491,416,761 - 91,562,592 (-)NCBIT2T-CHM13v2.0
Abcg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39658,561,476 - 58,669,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl658,561,508 - 58,672,661 (+)EnsemblGRCm39 Ensembl
GRCm38658,584,491 - 58,692,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl658,584,523 - 58,695,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv37658,546,666 - 58,642,445 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36658,526,250 - 58,622,029 (+)NCBIMGSCv36mm8
Celera660,752,972 - 60,848,739 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.82NCBI
Abcg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8489,006,056 - 89,132,915 (+)NCBIGRCr8
mRatBN7.2487,676,241 - 87,802,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl487,745,319 - 87,802,409 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx492,961,189 - 93,018,372 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0488,736,572 - 88,793,756 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0487,105,627 - 87,162,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0488,765,441 - 88,890,268 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl488,832,178 - 88,890,621 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04153,587,206 - 153,712,481 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4487,502,584 - 87,560,017 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1487,747,008 - 87,804,442 (+)NCBI
Celera482,507,731 - 82,564,802 (+)NCBICelera
Cytogenetic Map4q24NCBI
ABCG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2386,093,103 - 86,236,613 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1486,353,103 - 86,499,020 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0480,379,108 - 80,446,641 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1491,101,321 - 91,170,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl491,101,321 - 91,170,157 (-)Ensemblpanpan1.1panPan2
ABCG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13211,443,778 - 11,517,674 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3211,443,780 - 11,517,674 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3230,372,283 - 30,510,869 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03211,496,580 - 11,635,323 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3211,496,586 - 11,573,345 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13211,580,165 - 11,719,079 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03211,406,011 - 11,544,317 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03228,508,945 - 28,549,001 (+)NCBIUU_Cfam_GSD_1.0
UU_Cfam_GSD_1.03228,373,259 - 28,501,671 (+)NCBIUU_Cfam_GSD_1.0
ABCG2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8130,775,444 - 130,945,393 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18130,853,414 - 130,945,388 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28140,193,291 - 140,228,765 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1736,458,110 - 36,599,753 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603715,206,025 - 15,348,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005401452   ⟹   XP_005401509
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547412,365,903 - 12,408,715 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401509 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000011970.1
  ENSCLAP00000011971
  ENSCLAP00000011971.1
RefSeq Acc Id: XP_005401509   ⟸   XM_005401452
- UniProtKB: A0A8C2VB20 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008261 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012111.1 UniProtKB/TrEMBL
  ENSCLAT00000012112 ENTREZGENE
  ENSCLAT00000012112.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC_2_trans UniProtKB/TrEMBL
  ABC_transporter-like_ATP-bd UniProtKB/TrEMBL
  ABCG_dom UniProtKB/TrEMBL
  ABCG_transporters UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Abcg2 ENTREZGENE
PANTHER ABC TRANSPORTER G FAMILY MEMBER 28 UniProtKB/TrEMBL
  PTHR48041:SF92 UniProtKB/TrEMBL
Pfam ABC2_membrane UniProtKB/TrEMBL
  ABC2_membrane_7 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VB20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VF02_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-11-15 Abcg2  ATP binding cassette subfamily G member 2 (JR blood group)  Abcg2  ATP binding cassette subfamily G member 2 (Junior blood group)  Symbol and/or name change 5135510 APPROVED
2016-08-16 Abcg2  ATP binding cassette subfamily G member 2 (Junior blood group)    ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)  Symbol and/or name change 5135510 APPROVED
2015-08-25 Abcg2  ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)    ATP-binding cassette, sub-family G (WHITE), member 2  Symbol and/or name change 5135510 APPROVED