Pkn2 (protein kinase N2) - Rat Genome Database

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Gene: Pkn2 (protein kinase N2) Chinchilla lanigera
Analyze
Symbol: Pkn2
Name: protein kinase N2
RGD ID: 8930811
Description: ENCODES a protein that exhibits histone deacetylase binding (ortholog); kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN apical junction assembly (ortholog); epithelial cell migration (ortholog); positive regulation of cytokinesis (ortholog); FOUND IN apical junction complex (ortholog); centrosome (ortholog); cleavage furrow (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase N2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554235,467,017 - 5,575,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554235,467,017 - 5,575,435 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Pkn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554235,467,017 - 5,575,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554235,467,017 - 5,575,435 (-)NCBIChiLan1.0ChiLan1.0
PKN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38188,684,273 - 88,836,255 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl188,684,222 - 88,836,255 (+)EnsemblGRCh38hg38GRCh38
GRCh37189,149,956 - 89,301,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36188,922,510 - 89,074,526 (+)NCBINCBI36Build 36hg18NCBI36
Build 34188,862,276 - 89,011,443NCBI
Celera187,395,729 - 87,547,728 (+)NCBICelera
Cytogenetic Map1p22.2NCBI
HuRef187,267,203 - 87,419,414 (+)NCBIHuRef
CHM1_1189,265,019 - 89,416,992 (+)NCBICHM1_1
T2T-CHM13v2.0188,527,688 - 88,679,643 (+)NCBIT2T-CHM13v2.0
Pkn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393142,496,663 - 142,587,765 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3142,496,663 - 142,587,765 (-)EnsemblGRCm39 Ensembl
GRCm383142,790,902 - 142,882,004 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3142,790,902 - 142,882,004 (-)EnsemblGRCm38mm10GRCm38
MGSCv373142,453,866 - 142,544,968 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363142,730,845 - 142,819,376 (-)NCBIMGSCv36mm8
Celera3149,222,971 - 149,314,408 (-)NCBICelera
Cytogenetic Map3H1NCBI
cM Map366.69NCBI
Pkn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82234,454,001 - 234,559,369 (-)NCBIGRCr8
mRatBN7.22231,793,584 - 231,898,953 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2231,793,584 - 231,898,953 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2239,572,538 - 239,677,842 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02237,466,818 - 237,572,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02232,330,191 - 232,435,493 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02248,735,699 - 248,840,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2248,735,699 - 248,840,735 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02267,265,825 - 267,370,861 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42240,903,608 - 241,009,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12240,892,652 - 240,944,091 (-)NCBI
Celera2223,803,766 - 223,906,746 (-)NCBICelera
Cytogenetic Map2q44NCBI
PKN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21138,134,707 - 138,292,307 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11137,290,425 - 137,447,311 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0191,395,885 - 91,551,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1190,147,949 - 90,302,741 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl190,202,299 - 90,302,741 (+)Ensemblpanpan1.1panPan2
PKN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1659,556,668 - 59,638,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl659,559,124 - 59,709,926 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha662,264,725 - 62,394,692 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0660,067,704 - 60,197,746 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl660,067,567 - 60,220,888 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1659,633,009 - 59,762,681 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0659,588,332 - 59,718,360 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0660,074,127 - 60,204,202 (-)NCBIUU_Cfam_GSD_1.0
Pkn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505899,124,068 - 99,240,257 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936732198,647 - 314,947 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936732199,208 - 315,094 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4127,573,703 - 127,709,942 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14127,579,097 - 127,709,982 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24139,804,474 - 139,934,537 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12044,582,227 - 44,739,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2044,584,576 - 44,739,761 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603373,164,387 - 73,324,100 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247428,742,473 - 8,865,281 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247428,740,102 - 8,865,483 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000005665   ⟹   ENSCLAP00000005564
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554235,467,017 - 5,545,760 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000005666   ⟹   ENSCLAP00000005565
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554235,469,326 - 5,575,620 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000005667   ⟹   ENSCLAP00000005566
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554235,469,326 - 5,545,329 (-)Ensembl
RefSeq Acc Id: XM_013514513   ⟹   XP_013369967
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554235,467,017 - 5,575,435 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013369967 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005564.1
  ENSCLAP00000005565
  ENSCLAP00000005565.1
  ENSCLAP00000005566.1
RefSeq Acc Id: XP_013369967   ⟸   XM_013514513
- UniProtKB: A0A8C2UUJ4 (UniProtKB/TrEMBL),   A0A8C2UTE6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000005566   ⟸   ENSCLAT00000005667
Ensembl Acc Id: ENSCLAP00000005565   ⟸   ENSCLAT00000005666
Ensembl Acc Id: ENSCLAP00000005564   ⟸   ENSCLAT00000005665
Protein Domains
AGC-kinase C-terminal   C2   Protein kinase   REM-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003946 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005665.1 UniProtKB/TrEMBL
  ENSCLAT00000005666 ENTREZGENE
  ENSCLAT00000005666.1 UniProtKB/TrEMBL
  ENSCLAT00000005667.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  HR1 repeat UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2_PKN UniProtKB/TrEMBL
  HR1_rho-bd UniProtKB/TrEMBL
  HR1_rpt_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  PKN_HR1_1 UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser_Thr_kinase_AGC UniProtKB/TrEMBL
NCBI Gene Pkn2 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/TrEMBL
  SERINE_THREONINE-PROTEIN KINASE N2 UniProtKB/TrEMBL
Pfam HR1 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  REM_1 UniProtKB/TrEMBL
SMART Hr1 UniProtKB/TrEMBL
  S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF46585 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2UTE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UUJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YKK8_CHILA UniProtKB/TrEMBL