Gria2 (glutamate ionotropic receptor AMPA type subunit 2) - Rat Genome Database

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Gene: Gria2 (glutamate ionotropic receptor AMPA type subunit 2) Chinchilla lanigera
Analyze
Symbol: Gria2
Name: glutamate ionotropic receptor AMPA type subunit 2
RGD ID: 8929285
Description: ENCODES a protein that exhibits AMPA glutamate receptor activity (ortholog); amyloid-beta binding (ortholog); cytoskeletal protein binding (ortholog); INVOLVED IN cellular response to amine stimulus (ortholog); cellular response to brain-derived neurotrophic factor stimulus (ortholog); cellular response to glycine (ortholog); PARTICIPATES IN N-cadherin signaling pathway; ASSOCIATED WITH allergic rhinitis (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN AMPA glutamate receptor complex (ortholog); asymmetric synapse (ortholog); axon (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate receptor 2; glutamate receptor, ionotropic, AMPA 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554719,970,403 - 10,108,898 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gria2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554719,970,403 - 10,108,898 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBIChiLan1.0ChiLan1.0
GRIA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384157,220,120 - 157,366,075 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4157,204,182 - 157,387,146 (+)EnsemblGRCh38hg38GRCh38
GRCh374158,141,272 - 158,287,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364158,361,186 - 158,506,677 (+)NCBINCBI36Build 36hg18NCBI36
Build 344158,499,639 - 158,642,707NCBI
Celera4155,484,938 - 155,630,358 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4153,892,713 - 154,037,902 (+)NCBIHuRef
CHM1_14158,118,907 - 158,264,349 (+)NCBICHM1_1
T2T-CHM13v2.04160,550,597 - 160,711,660 (+)NCBIT2T-CHM13v2.0
Gria2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39380,588,757 - 80,711,534 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl380,588,757 - 80,710,142 (-)EnsemblGRCm39 Ensembl
GRCm38380,681,450 - 80,804,227 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl380,681,450 - 80,802,835 (-)EnsemblGRCm38mm10GRCm38
MGSCv37380,488,858 - 80,606,713 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36380,770,863 - 80,888,718 (-)NCBIMGSCv36mm8
Celera380,695,789 - 80,807,271 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.5NCBI
Gria2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82168,247,490 - 168,367,616 (-)NCBIGRCr8
mRatBN7.22165,949,379 - 166,069,510 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2165,947,521 - 166,069,510 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2173,141,275 - 173,261,498 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02171,155,659 - 171,275,864 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02165,764,515 - 165,884,705 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02179,584,302 - 179,704,629 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2179,584,308 - 179,704,629 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02198,991,672 - 199,113,059 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42172,265,155 - 172,385,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12172,216,247 - 172,335,391 (-)NCBI
Celera2159,991,989 - 160,110,044 (-)NCBICelera
Cytogenetic Map2q33NCBI
GRIA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23155,113,339 - 155,258,801 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14155,468,514 - 155,614,022 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04149,566,563 - 149,712,135 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14161,380,933 - 161,524,376 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4161,380,933 - 161,524,376 (+)Ensemblpanpan1.1panPan2
GRIA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11554,634,332 - 54,710,711 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1554,634,335 - 54,708,184 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1554,899,350 - 55,051,036 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01555,280,110 - 55,432,031 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1555,280,105 - 55,432,019 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11554,520,013 - 54,671,698 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01554,628,421 - 54,780,188 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01554,943,850 - 55,095,680 (+)NCBIUU_Cfam_GSD_1.0
Gria2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530135,606,967 - 35,746,531 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365763,800,075 - 3,941,003 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365763,800,369 - 3,940,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl846,078,276 - 46,241,914 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1846,078,122 - 46,247,144 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2848,116,966 - 48,280,583 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17103,808,789 - 103,957,947 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7103,808,797 - 103,953,040 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603783,492,906 - 83,648,026 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gria2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248481,135,032 - 1,261,087 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248481,132,939 - 1,261,110 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000011056   ⟹   ENSCLAP00000010921
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554719,970,403 - 10,108,898 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000011057   ⟹   ENSCLAP00000010922
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554719,970,403 - 10,108,898 (-)Ensembl
RefSeq Acc Id: XM_005400940   ⟹   XP_005400997
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005400941   ⟹   XP_005400998
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005400942   ⟹   XP_005400999
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005400943   ⟹   XP_005401000
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554719,974,888 - 10,108,871 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001237063
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554719,970,396 - 10,108,871 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005400997   ⟸   XM_005400940
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005400999   ⟸   XM_005400942
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V6Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005400998   ⟸   XM_005400941
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YN55 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401000   ⟸   XM_005400943
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000010921   ⟸   ENSCLAT00000011056
Ensembl Acc Id: ENSCLAP00000010922   ⟸   ENSCLAT00000011057

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007538 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011056 ENTREZGENE
  ENSCLAT00000011056.1 UniProtKB/TrEMBL
  ENSCLAT00000011057 ENTREZGENE
  ENSCLAT00000011057.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  Glu/Gly-bd UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/TrEMBL
  Ionotropic_Glu_rcpt UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Gria2 ENTREZGENE
PANTHER GLUTAMATE RECEPTOR 2 UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/TrEMBL
  Lig_chan UniProtKB/TrEMBL
  Lig_chan-Glu_bd UniProtKB/TrEMBL
PRINTS NMDARECEPTOR UniProtKB/TrEMBL
SMART Lig_chan-Glu_bd UniProtKB/TrEMBL
  PBPe UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
  SSF53822 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C2V6Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YN55 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Gria2  glutamate ionotropic receptor AMPA type subunit 2    glutamate receptor, ionotropic, AMPA 2  Symbol and/or name change 5135510 APPROVED