Gpd2 (glycerol-3-phosphate dehydrogenase 2) - Rat Genome Database

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Gene: Gpd2 (glycerol-3-phosphate dehydrogenase 2) Chinchilla lanigera
Analyze
Symbol: Gpd2
Name: glycerol-3-phosphate dehydrogenase 2
RGD ID: 8927652
Description: ENCODES a protein that exhibits glycerol-3-phosphate dehydrogenase (quinone) activity (ortholog); glycerol-3-phosphate dehydrogenase [NAD(P)+] activity (ortholog); INVOLVED IN camera-type eye development (ortholog); gluconeogenesis (ortholog); glycerol-3-phosphate metabolic process (ortholog); PARTICIPATES IN D-glycericacidemia pathway; electron transport chain pathway; familial lipoprotein lipase deficiency pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); COVID-19 (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544916,695,435 - 16,802,908 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544916,695,855 - 16,804,184 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gpd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544916,695,435 - 16,802,908 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544916,695,855 - 16,804,184 (-)NCBIChiLan1.0ChiLan1.0
GPD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382156,400,281 - 156,586,403 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2156,435,290 - 156,613,735 (+)EnsemblGRCh38hg38GRCh38
GRCh372157,292,064 - 157,442,915 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362157,000,211 - 157,151,161 (+)NCBINCBI36Build 36hg18NCBI36
Build 342157,118,427 - 157,265,427NCBI
Celera2150,905,211 - 151,056,180 (+)NCBICelera
Cytogenetic Map2q24.1NCBI
HuRef2149,177,055 - 149,329,145 (+)NCBIHuRef
CHM1_12157,298,013 - 157,448,944 (+)NCBICHM1_1
T2T-CHM13v2.02156,852,575 - 157,039,187 (+)NCBIT2T-CHM13v2.0
Gpd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39257,127,690 - 57,260,731 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl257,127,647 - 57,260,731 (+)EnsemblGRCm39 Ensembl
GRCm38257,237,678 - 57,370,719 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl257,237,635 - 57,370,719 (+)EnsemblGRCm38mm10GRCm38
MGSCv37257,090,089 - 57,223,130 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36257,053,683 - 57,182,998 (+)NCBIMGSCv36mm8
Celera258,979,703 - 59,113,189 (+)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map231.66NCBI
Gpd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8362,209,432 - 62,346,590 (+)NCBIGRCr8
mRatBN7.2341,800,552 - 41,937,729 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl341,801,930 - 41,936,901 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx345,140,050 - 45,269,752 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0353,724,802 - 53,854,494 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0351,516,921 - 51,648,631 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0343,223,892 - 43,359,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl343,255,567 - 43,359,074 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0348,295,428 - 48,426,568 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4338,980,634 - 39,114,492 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1338,877,005 - 39,010,860 (+)NCBI
Celera339,895,025 - 40,025,154 (+)NCBICelera
Cytogenetic Map3q21NCBI
GPD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21359,103,098 - 59,254,023 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B59,118,153 - 59,268,997 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B43,694,744 - 43,845,764 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B160,938,504 - 161,090,254 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B160,938,514 - 161,117,320 (+)Ensemblpanpan1.1panPan2
GPD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1362,678,749 - 2,780,173 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl362,681,188 - 2,777,535 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha362,774,808 - 2,917,377 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0362,761,016 - 2,901,673 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl362,760,786 - 2,901,655 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1362,760,613 - 2,903,976 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0362,820,368 - 2,961,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0362,860,213 - 3,000,818 (+)NCBIUU_Cfam_GSD_1.0
Gpd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303119,785,975 - 119,930,842 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646921,705,421 - 21,831,745 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646921,705,421 - 21,833,143 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1563,619,762 - 63,728,633 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11563,592,723 - 63,728,636 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21570,841,147 - 70,946,575 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11041,832,772 - 41,984,109 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1041,834,013 - 41,986,423 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040157,577,884 - 157,727,701 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247329,298,156 - 9,447,883 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000004091   ⟹   ENSCLAP00000004010
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544916,695,435 - 16,802,908 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000004092   ⟹   ENSCLAP00000004011
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544916,695,435 - 16,802,608 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000004093   ⟹   ENSCLAP00000004012
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544916,699,004 - 16,802,600 (-)Ensembl
RefSeq Acc Id: XM_005393414   ⟹   XP_005393471
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544916,695,855 - 16,804,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393415   ⟹   XP_005393472
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544916,695,855 - 16,804,184 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005393471 (Get FASTA)   NCBI Sequence Viewer  
  XP_005393472 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004010
  ENSCLAP00000004010.1
  ENSCLAP00000004011
  ENSCLAP00000004011.1
  ENSCLAP00000004012.1
RefSeq Acc Id: XP_005393472   ⟸   XM_005393415
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UTC7 (UniProtKB/TrEMBL),   A0A8C2UVQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005393471   ⟸   XM_005393414
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UQH2 (UniProtKB/TrEMBL),   A0A8C2UVQ5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000004012   ⟸   ENSCLAT00000004093
Ensembl Acc Id: ENSCLAP00000004010   ⟸   ENSCLAT00000004091
Ensembl Acc Id: ENSCLAP00000004011   ⟸   ENSCLAT00000004092
Protein Domains
EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004091 ENTREZGENE
  ENSCLAT00000004091.1 UniProtKB/TrEMBL
  ENSCLAT00000004092 ENTREZGENE
  ENSCLAT00000004092.1 UniProtKB/TrEMBL
  ENSCLAT00000004093.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.870 UniProtKB/TrEMBL
  3.50.50.60 UniProtKB/TrEMBL
  D-Amino Acid Oxidase, subunit A, domain 2 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro DAO_C UniProtKB/TrEMBL
  DAO_C_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  FAD-dep_OxRdtase UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/TrEMBL
  G3P_DH_FAD-dep UniProtKB/TrEMBL
NCBI Gene Gpd2 ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR11985 UniProtKB/TrEMBL
Pfam DAO UniProtKB/TrEMBL
  DAO_C UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PRINTS FADG3PDH UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  FAD_G3PDH_1 UniProtKB/TrEMBL
  FAD_G3PDH_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP FAD-linked reductases, C-terminal domain UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF51905 UniProtKB/TrEMBL
UniProt A0A8C2UQH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UTC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UVQ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Gpd2  glycerol-3-phosphate dehydrogenase 2    glycerol-3-phosphate dehydrogenase 2 (mitochondrial)  Symbol and/or name change 5135510 APPROVED