Shc2 (SHC adaptor protein 2) - Rat Genome Database

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Gene: Shc2 (SHC adaptor protein 2) Chinchilla lanigera
Analyze
Symbol: Shc2
Name: SHC adaptor protein 2
RGD ID: 8927634
Description: ASSOCIATED WITH genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554957,216,806 - 7,236,056 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Shc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554957,216,806 - 7,236,056 (+)NCBIChiLan1.0ChiLan1.0
SHC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819416,589 - 461,033 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19416,589 - 461,033 (-)EnsemblGRCh38hg38GRCh38
GRCh3719416,589 - 461,033 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619367,583 - 411,832 (-)NCBINCBI36Build 36hg18NCBI36
Build 3419411,901 - 411,957NCBI
Cytogenetic Map19p13.3NCBI
HuRef19185,638 - 230,388 (-)NCBIHuRef
CHM1_119413,915 - 460,585 (-)NCBICHM1_1
T2T-CHM13v2.019364,869 - 412,538 (-)NCBIT2T-CHM13v2.0
Shc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,453,768 - 79,473,752 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,453,885 - 79,473,752 (-)EnsemblGRCm39 Ensembl
GRCm381079,617,934 - 79,637,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,618,051 - 79,637,918 (-)EnsemblGRCm38mm10GRCm38
MGSCv371079,080,679 - 79,100,663 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,021,033 - 79,040,990 (-)NCBIMGSCv36mm8
Celera1080,631,300 - 80,651,284 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Shc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,717,320 - 10,739,539 (+)NCBIGRCr8
mRatBN7.2710,066,705 - 10,088,926 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,066,705 - 10,088,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,948,071 - 12,970,304 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,826,155 - 14,848,390 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,685,795 - 12,708,193 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,948,952 - 12,971,174 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,948,952 - 12,971,174 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,117,670 - 13,139,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,583,380 - 11,605,675 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,582,082 - 11,604,162 (+)NCBI
Celera78,239,277 - 8,261,491 (+)NCBICelera
Cytogenetic Map7q11NCBI
SHC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2204,723,555 - 4,787,947 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,967,330 - 4,025,675 (-)NCBINHGRI_mPanPan1
PanPan1.119367,348 - 405,054 (-)NCBIpanpan1.1PanPan1.1panPan2
SHC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12058,001,442 - 58,023,201 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,804,227 - 57,825,834 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,744,465 - 58,766,097 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12057,798,377 - 57,819,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,278,093 - 58,299,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,481,722 - 58,503,345 (+)NCBIUU_Cfam_GSD_1.0
Shc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,725,930 - 217,743,083 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493658891,700 - 109,784 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1277,812,379 - 77,844,032 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103233559
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16151,955 - 193,626 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366687521,359 - 28,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248287,978,031 - 7,996,448 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013505336   ⟹   XP_013360790
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554957,216,806 - 7,236,056 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013360790 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000013683.1
  ENSCLAP00000013684
  ENSCLAP00000013684.1
Reference Protein Sequences
RefSeq Acc Id: XP_013360790   ⟸   XM_013505336
- UniProtKB: A0A8C2VJT3 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
PID   SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009456 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000013838.1 UniProtKB/TrEMBL
  ENSCLAT00000013839 ENTREZGENE
  ENSCLAT00000013839.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PID_Shc-like UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SHC_SH2 UniProtKB/TrEMBL
NCBI Gene Shc2 ENTREZGENE
PANTHER PTHR10337:SF5 UniProtKB/TrEMBL
  SHC TRANSFORMING PROTEIN UniProtKB/TrEMBL
Pfam PID UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SHCPIDOMAIN UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C2VDA4_CHILA UniProtKB/TrEMBL
  A0A8C2VJT3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Shc2  SHC adaptor protein 2    SHC (Src homology 2 domain containing) transforming protein 2  Symbol and/or name change 5135510 APPROVED