Tbxa2r (thromboxane A2 receptor) - Rat Genome Database

Name: Tbxa2r
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Tbxa2r (thromboxane A2 receptor) Chinchilla lanigera

Analyze

Symbol:

Tbxa2r

Name:

thromboxane A2 receptor

RGD ID:

8924957

Description:

ENCODES a protein that exhibits thromboxane receptor activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); inflammatory response (ortholog); negative regulation of cell migration involved in sprouting angiogenesis (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH adult respiratory distress syndrome (ortholog); aspirin-induced respiratory disease (ortholog); asthma (ortholog); FOUND IN acrosomal vesicle (ortholog); nuclear speck (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Mouse

Rat

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	5,539,889 - 5,557,441 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	5,539,382 - 5,557,441 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adult respiratory distress syndrome (ISO)

aspirin-induced respiratory disease (ISO)

asthma (ISO)

blood platelet disease (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Endotoxemia (ISO)

Experimental Pancreatitis (ISO)

hemorrhagic disease (ISO)

kidney failure (ISO)

Necrosis (ISO)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

Perennial Allergic Rhinitis (ISO)

Platelet-Type Bleeding Disorder 13 (ISO)

pulmonary embolism (ISO)

pulmonary eosinophilia (ISO)

rhinitis (ISO)

thrombocytopenia (ISO)

toxic shock syndrome (ISO)

Transplant Rejection (ISO)

Venous Thrombosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to lipopolysaccharide (ISO)

inflammatory response (ISO)

negative regulation of cell migration involved in sprouting angiogenesis (ISO)

positive regulation of angiogenesis (ISO)

positive regulation of blood coagulation (ISO)

positive regulation of blood pressure (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of smooth muscle contraction (ISO)

positive regulation of vasoconstriction (ISO)

regulation of vasoconstriction (ISO)

response to ethanol (ISO)

response to lipopolysaccharide (ISO)

response to nutrient (ISO)

response to testosterone (ISO)

response to xenobiotic stimulus (ISO)

second-messenger-mediated signaling (ISO)

smooth muscle contraction (ISO)

Cellular Component

acrosomal vesicle (ISO)

nuclear speck (ISO)

plasma membrane (ISO)

Molecular Function

protein binding (ISO)

thromboxane receptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data

Tbxa2r
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	5,539,889 - 5,557,441 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	5,539,382 - 5,557,441 (-)	NCBI	ChiLan1.0	ChiLan1.0

TBXA2R
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	3,594,507 - 3,606,875 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	3,594,507 - 3,606,875 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	3,594,505 - 3,606,873 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	3,545,504 - 3,557,658 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	3,545,503 - 3,557,658	NCBI
Celera	19	3,531,342 - 3,543,669 (-)	NCBI
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	3,359,876 - 3,372,152 (-)	NCBI		HuRef
CHM1_1	19	3,594,158 - 3,606,423 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	3,572,690 - 3,584,998 (-)	NCBI

Tbxa2r
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	81,164,102 - 81,171,008 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	10	81,164,565 - 81,171,006 (+)	Ensembl
GRCm38	10	81,328,268 - 81,335,174 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,328,731 - 81,335,172 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,791,476 - 80,797,917 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	10	80,731,860 - 80,738,301 (+)	NCBI			mm8
Celera	10	82,349,466 - 82,355,970 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Tbxa2r
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	8,383,347 - 8,390,753 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	7	8,383,378 - 8,388,176 (-)	Ensembl
Rnor_6.0	7	11,253,153 - 11,259,233 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,253,180 - 11,257,977 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	11,419,887 - 11,425,971 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	9,867,739 - 9,872,536 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	9,867,738 - 9,872,536 (-)	NCBI
Celera	7	6,572,330 - 6,577,127 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

TBXA2R
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	3,572,454 - 3,581,924 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	3,570,290 - 3,581,924 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	2,621,606 - 2,632,800 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

TBXA2R
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	55,819,866 - 55,829,395 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	55,824,410 - 55,828,980 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	55,545,953 - 55,554,659 (+)	NCBI
ROS_Cfam_1.0	20	56,480,706 - 56,489,446 (+)	NCBI
ROS_Cfam_1.0 Ensembl	20	56,480,655 - 56,490,031 (+)	Ensembl
UMICH_Zoey_3.1	20	55,536,340 - 55,545,063 (+)	NCBI
UNSW_CanFamBas_1.0	20	56,019,809 - 56,028,498 (+)	NCBI
UU_Cfam_GSD_1.0	20	56,218,510 - 56,227,219 (+)	NCBI

Tbxa2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	215,786,562 - 215,793,960 (+)	NCBI
SpeTri2.0	NW_004936588	2,040,712 - 2,044,635 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBXA2R
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	75,068,698 - 75,087,731 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	75,068,413 - 75,081,305 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOC103233689
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	3,354,358 - 3,365,779 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	6	3,355,314 - 3,359,761 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666081	5,119,245 - 5,134,213 (+)	NCBI	Vero_WHO_p1.0

Tbxa2r
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,291,167 - 6,309,482 (-)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624828	6,291,010 - 6,312,438 (-)	NCBI	HetGla_female_1.0		hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013505254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01062011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01062012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01062013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01180494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01026478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCLAT00000015578 ⟹ ENSCLAP00000015417

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955495	5,539,889 - 5,557,441 (-)	Ensembl

RefSeq Acc Id:

XM_013505254 ⟹ XP_013360708

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955495	5,539,382 - 5,557,441 (-)	NCBI

Sequence:

show sequence

GGAAGCGGCGAGGCCGGCGGGAGGGGCGGGGCGGGGCCGGCCCGGGGGCGGGGCCGGGCAGCCG
GGCGGGCGGGCGCGGAGTCGGGGACAGAGCGGAGACCGCGCCGCCAACCCCAGCCCACCCCGCC
GCGCTCAGACCCGGCTGCGGGCGGCCCCGCGCCCCGGCGCCCCTGCCACCACGCCCTCCACCTG
GGCCCCGCCGCGACCTGCAGCTGCCCGACGTCTCTCGGGCCCGCTGCCCCGTGACTCAGTTTCC
CCGGAGGCCCCTGGGACGGCATTCCCGTATCCCACCCTTTGCCCTCCTCCTGCTTTCCCGCCGG
CCTCGAGGCGCCAGAGCACTCGCCCGACCCGCTTTCGGGACCACCGGACGCCCGGCGCGGCAGC
TCAGTGCTGGCCAGATGTGTCTGACCCTGCGCCAGCCCGATGGGGTGGTGACCCACTGACCCTA
CGCCCCTCCAGCGTCATGTGGCCCAACGATACTTCTCTGGGGCCGTGTTTCCGGCCCACAAACA
TCACGCTGGAGGAGCGGCGCCTGATTGCCTCGCCCTGGTTCGCAGCCTCCTTCTGTGCGGTGGG
CCTGGCCTCCAACCTGTTGGCGCTGAGCGCGCTGGCGGGTGCGCGGACGGGCGGCTCGAGCCCG
CGCTCCTCCTTCCTCACCTTCCTCTGCGGCCTGGTCCTCACGGACTTCTTGGGGCTGCTGGTCA
CCGGCATCATCGTCGTGTCCCAACACGCCATCCTCTTCGACTGGCGCGCCGTGGACCCGCGCTG
CCGCCTCTGCGACTTCATGGGCGTCGCCATGGTCTTCTTCGGCCTGTGCCCTCTGCTGCTGGGT
GCCGCCATGGCCTCGGAGCGCTTCCTGGGCATCACGCGGCCCTTCTCCCGGCCGGCGGCCGCCT
CCCCGCGCCGCGCCTGGGACTCGGTGGCGCTGGTGTGGGCGGCGGCGCTGGCGCTCGGGCTGCT
GCCGCTGCTGGGGCTGGGCCGCTACTCGCTGCAGTACCCGGGCTCCTGGTGCTTCCTGACGCTG
GGCGCGCGGCCGGGCGACGTGGCCTTCGCGCTGCTCTTCGCGCTGCTGGGCGGCCTCTCGGTGG
CGCTGTCCTTCGTGCTCAACACCATCAGCGTGGCCGCCCTGTGCCGCGTCTACCACGGCCGCCA
GGCCGCCCAGCAGCGCCCGCGGGACTGCGAGGTGGAGATGATGGTGCAGCTACTGGGCATCATG
GTGGTGGCCAGCGTCTGCTGGATGCCCTTGCTGGTCTTCATCGCACAGACCGTGCTGAGGACGC
CGCCGGCCATGAGCGCCTCTGGCCAGCTGTCCCGGGCCACCGAGCGGCAGTTGCTCATCTACCT
GCGCGTGGCCACCTGGAACCAGATCCTGGACCCCTGGGTCTACATCCTCTTCCGCCGCGCCGTG
CTGCGGCGTCTACACCCGCGCCTCAGCATGCGGCCCCGGTCGCTGTCCCTGCAGCCACAGCTCT
CCCAGGACGCCAGGGGGCCACTGTGACTGCGGAGTGCCCTTTGCTTGCCCCAGGTGCTCCCTGG
TCCCTGTGTAACACCCTGCCGTGCCACTCAGAGCCCCCAGCACCCTGCAGGCCCCCAGGGGGCG
CCTGGAAGGAATCGGACTGTGAAGCCCAGTGAAGTGAGGGTTCTTCCGGAAGCCCTCTGAGCTG
GGGGTGCTGTGATCCCTAAGAGGAGGCCTTGTGGGGTTAGAGACCTCCTCTGCAACCCTATCTG
GAGCGGCTTTGCCTAGAACAGGCTCAGAGCGCACGGCTTGGCGGTGCATGTCATCAGAGCTAGT
TGGGAGGCTGAGGCAGGAGGATTGCAAGTTCGAACTCGGCCTGAGCAATTTAGCCATTTAGTGA
GATCCTGTCTCAAAATTTTAAAGAGGGGCGGGGATGCAGATCAGTGCTGAGCACTTGCTTAGCA
CGTGCACAGCCCTGGGTTGGACCCCTAACACCTCAAAAAATAAAGTGAACAGTAAGAGGGGCAC
CCCCTCTCTTGCCAAAATAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013360708	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_013360708 ⟸ XM_013505254

- Sequence:

show sequence

MWPNDTSLGPCFRPTNITLEERRLIASPWFAASFCAVGLASNLLALSALAGARTGGSSPRSSFL
TFLCGLVLTDFLGLLVTGIIVVSQHAILFDWRAVDPRCRLCDFMGVAMVFFGLCPLLLGAAMAS
ERFLGITRPFSRPAAASPRRAWDSVALVWAAALALGLLPLLGLGRYSLQYPGSWCFLTLGARPG
DVAFALLFALLGGLSVALSFVLNTISVAALCRVYHGRQAAQQRPRDCEVEMMVQLLGIMVVASV
CWMPLLVFIAQTVLRTPPAMSASGQLSRATERQLLIYLRVATWNQILDPWVYILFRRAVLRRLH
PRLSMRPRSLSLQPQLSQDARGPL

hide sequence

RefSeq Acc Id:

ENSCLAP00000015417 ⟸ ENSCLAT00000015578

Protein Domains

G_PROTEIN_RECEP_F1_2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010610	Ensembl, UniProtKB/TrEMBL
Ensembl Protein	ENSCLAP00000015417.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000015578.1	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Prostanoid_rcpt	UniProtKB/TrEMBL
	Thbox_rcpt	UniProtKB/TrEMBL
NCBI Gene	Tbxa2r	ENTREZGENE
PANTHER	PTHR11866	UniProtKB/TrEMBL
PRINTS	PROSTANOIDR	UniProtKB/TrEMBL
	THROMBOXANER	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
UniProt	A0A8C2VMB0_CHILA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

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Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)