Klhl1 (kelch like family member 1) - Rat Genome Database

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Gene: Klhl1 (kelch like family member 1) Chinchilla lanigera
Analyze
Symbol: Klhl1
Name: kelch like family member 1
RGD ID: 8924337
Description: INVOLVED IN adult walking behavior (ortholog); cerebellar Purkinje cell layer development (ortholog); dendrite development (ortholog); ASSOCIATED WITH chromosome 13q14 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch-like family member 1; kelch-like protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540436,304,326 - 36,697,236 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540436,304,862 - 36,696,901 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Klhl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540436,304,326 - 36,697,236 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540436,304,862 - 36,696,901 (+)NCBIChiLan1.0ChiLan1.0
KLHL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381369,700,597 - 70,108,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1369,700,594 - 70,108,493 (-)EnsemblGRCh38hg38GRCh38
GRCh371370,274,729 - 70,682,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361369,172,726 - 69,580,460 (-)NCBINCBI36Build 36hg18NCBI36
Build 341369,172,726 - 69,580,460NCBI
Celera1351,176,734 - 51,584,696 (-)NCBICelera
Cytogenetic Map13q21.33NCBI
HuRef1350,976,143 - 51,384,644 (-)NCBIHuRef
CHM1_11370,242,241 - 70,650,179 (-)NCBICHM1_1
T2T-CHM13v2.01368,922,478 - 69,330,323 (-)NCBIT2T-CHM13v2.0
Klhl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391496,342,695 - 96,756,525 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1496,340,172 - 96,756,538 (-)EnsemblGRCm39 Ensembl
GRCm381496,105,265 - 96,519,034 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1496,102,736 - 96,519,102 (-)EnsemblGRCm38mm10GRCm38
MGSCv371496,504,484 - 96,918,253 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361494,988,399 - 95,402,168 (-)NCBIMGSCv36mm8
Celera1494,679,542 - 95,128,348 (-)NCBICelera
Cytogenetic Map14E2.1NCBI
cM Map1446.92NCBI
Klhl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81579,106,164 - 79,550,684 (-)NCBIGRCr8
mRatBN7.21572,698,191 - 73,142,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1572,699,094 - 73,142,594 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1576,715,916 - 77,145,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01577,801,146 - 78,231,047 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01574,740,051 - 75,169,929 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01580,270,846 - 80,714,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1580,271,731 - 80,713,153 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01583,810,351 - 84,250,513 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41579,306,914 - 79,772,396 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11579,322,860 - 79,787,587 (-)NCBI
Celera1571,996,058 - 72,423,584 (-)NCBICelera
Cytogenetic Map15q21NCBI
KLHL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21471,257,066 - 71,685,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11369,847,850 - 70,276,570 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01350,906,581 - 51,335,692 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11369,694,185 - 70,119,241 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1369,691,537 - 70,118,448 (-)Ensemblpanpan1.1panPan2
KLHL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12224,190,862 - 24,554,451 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2224,191,778 - 24,555,120 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2224,044,013 - 24,406,868 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02224,501,555 - 24,889,956 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2224,502,463 - 24,889,867 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12224,144,239 - 24,507,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02224,230,744 - 24,587,985 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02224,289,783 - 24,660,217 (-)NCBIUU_Cfam_GSD_1.0
Klhl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945135,093,965 - 135,462,773 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651110,511,192 - 10,879,146 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651110,511,200 - 10,879,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1142,033,851 - 42,419,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11142,033,842 - 42,420,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21146,253,406 - 46,664,342 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1348,812,816 - 49,237,894 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl348,812,845 - 49,086,381 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660464,765,419 - 5,551,660 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474830,948,029 - 31,387,128 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474830,948,092 - 31,387,128 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005374194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01004158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01004176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDF01141646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000003060   ⟹   ENSCLAP00000002998
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540436,304,326 - 36,697,236 (+)Ensembl
RefSeq Acc Id: XM_005374194   ⟹   XP_005374251
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540436,304,862 - 36,696,901 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374251 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002998
  ENSCLAP00000002998.1
Reference Protein Sequences
RefSeq Acc Id: XP_005374251   ⟸   XM_005374194
- UniProtKB: A0A8C2YJD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002998   ⟸   ENSCLAT00000003060
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002153 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003060 ENTREZGENE
  ENSCLAT00000003060.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene Klhl1 ENTREZGENE
PANTHER ACTIN-BINDING PROTEIN IPP UniProtKB/TrEMBL
  KELCH PROTEIN UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A8C2YJD2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Klhl1  kelch like family member 1    kelch-like family member 1  Symbol and/or name change 5135510 APPROVED