Chfr (checkpoint with forkhead and ring finger domains) - Rat Genome Database

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Gene: Chfr (checkpoint with forkhead and ring finger domains) Chinchilla lanigera
Analyze
Symbol: Chfr
Name: checkpoint with forkhead and ring finger domains
RGD ID: 8924018
Description: ENCODES a protein that exhibits nucleotide binding (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN meiotic spindle checkpoint signaling (ortholog); mitotic cell cycle (ortholog); mitotic G2/M transition checkpoint (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH Endometrial Neoplasms (ortholog); lung non-small cell carcinoma (ortholog); Stomach Neoplasms (ortholog); FOUND IN nucleus (ortholog); PML body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase CHFR
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482233,486 - 267,064 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955482233,485 - 267,064 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (ISO)
PML body  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Chfr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955482233,486 - 267,064 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955482233,485 - 267,064 (+)NCBIChiLan1.0ChiLan1.0
CHFR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl12132,822,187 - 132,956,304 (-)EnsemblGRCh38hg38GRCh38
GRCh3812132,832,356 - 132,887,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712133,408,942 - 133,464,204 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612131,927,011 - 131,974,257 (-)NCBINCBI36hg18NCBI36
Build 3412132,027,287 - 132,074,534NCBI
Celera12133,115,986 - 133,164,103 (-)NCBI
Cytogenetic Map12q24.33NCBI
HuRef12130,193,539 - 130,240,836 (-)NCBIHuRef
CHM1_112133,236,937 - 133,284,187 (-)NCBICHM1_1
Chfr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395110,283,599 - 110,319,839 (+)NCBIGRCm39mm39
GRCm39 Ensembl5110,283,708 - 110,319,838 (+)Ensembl
GRCm385110,135,755 - 110,171,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5110,135,842 - 110,171,972 (+)EnsemblGRCm38mm10GRCm38
MGSCv375110,564,859 - 110,600,991 (+)NCBIGRCm37mm9NCBIm37
MGSCv365110,376,162 - 110,412,271 (+)NCBImm8
Celera5107,262,325 - 107,298,846 (+)NCBICelera
Cytogenetic Map5FNCBI
Chfr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21246,504,497 - 46,538,104 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1246,504,497 - 46,538,014 (-)Ensembl
Rnor_6.01252,562,594 - 52,596,162 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1252,562,597 - 52,596,076 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,299,046 - 54,333,048 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41246,651,265 - 46,684,689 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11246,518,196 - 46,551,621 (-)NCBI
Celera1248,060,734 - 48,093,877 (-)NCBICelera
Cytogenetic Map12q16NCBI
LOC100974874
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112134,922,800 - 134,969,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12134,923,458 - 134,968,832 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012130,201,704 - 130,247,891 (-)NCBIMhudiblu_PPA_v0panPan3
CHFR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126251,369 - 324,699 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26294,909 - 324,696 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha26338,249 - 368,017 (+)NCBI
ROS_Cfam_1.026353,329 - 383,335 (+)NCBI
UMICH_Zoey_3.126294,908 - 324,410 (+)NCBI
UNSW_CanFamBas_1.026381,698 - 411,681 (+)NCBI
UU_Cfam_GSD_1.026313,264 - 342,862 (+)NCBI
Chfr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118121,966,521 - 121,996,058 (+)NCBI
SpeTri2.0NW_0049366602,725,019 - 2,754,564 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHFR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111128,175,768 - 128,207,710 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl11128,175,515 - 128,207,443 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037116,651,258 - 116,683,461 (+)NCBIVero_WHO_p1.0
Chfr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474728,187,356 - 28,222,041 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014927   ⟹   ENSCLAP00000014768
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955482233,486 - 267,064 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000014928   ⟹   ENSCLAP00000014769
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955482233,737 - 266,026 (+)Ensembl
RefSeq Acc Id: XM_005402938   ⟹   XP_005402995
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482233,486 - 267,064 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005402939   ⟹   XP_005402996
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955482233,485 - 267,064 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005402995 (Get FASTA)   NCBI Sequence Viewer  
  XP_005402996 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005402995   ⟸   XM_005402938
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005402996   ⟸   XM_005402939
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000014768   ⟸   ENSCLAT00000014927
RefSeq Acc Id: ENSCLAP00000014769   ⟸   ENSCLAT00000014928


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010189 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000014768 ENTREZGENE
Ensembl Transcript ENSCLAT00000014927 ENTREZGENE
NCBI Gene Chfr ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-02 Chfr  checkpoint with forkhead and ring finger domains    checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED