Pofut2 (protein O-fucosyltransferase 2)

Gene: Pofut2 (protein O-fucosyltransferase 2) Chinchilla lanigera

Analyze

Symbol:

Pofut2

Name:

protein O-fucosyltransferase 2

RGD ID:

8921322

Description:

ENCODES a protein that exhibits fucosyltransferase activity (ortholog); peptide-O-fucosyltransferase activity (ortholog); INVOLVED IN fucosylation (ortholog); mesoderm formation (ortholog); positive regulation of protein folding (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Axenfeld-Rieger syndrome type 3 (ortholog); cataract 9 multiple types (ortholog); FOUND IN Golgi apparatus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

GDP-fucose protein O-fucosyltransferase 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	41,972,717 - 41,984,095 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	41,972,833 - 41,984,095 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Axenfeld-Rieger syndrome type 3 (ISO)

cataract 9 multiple types (ISO)

developmental and epileptic encephalopathy 30 (ISO)

genetic disease (ISO)

homocystinuria (ISO)

Neurodevelopmental Disorders (ISO)

primary ciliary dyskinesia (ISO)

progressive myoclonus epilepsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fucosylation (ISO)

mesoderm formation (ISO)

positive regulation of protein folding (ISO)

protein O-linked fucosylation (ISO)

regulation of epithelial to mesenchymal transition (ISO)

regulation of gene expression (ISO)

regulation of secretion (ISO)

Cellular Component

Golgi apparatus (ISO)

Molecular Function

fucosyltransferase activity (ISO)

peptide-O-fucosyltransferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Pofut2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	41,972,717 - 41,984,095 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	41,972,833 - 41,984,095 (-)	NCBI	ChiLan1.0	ChiLan1.0

POFUT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	45,263,935 - 45,287,895 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	45,263,928 - 45,287,898 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	46,683,850 - 46,707,810 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	45,508,271 - 45,532,239 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	45,508,271 - 45,532,235	NCBI
Celera	21	31,791,392 - 31,815,364 (-)	NCBI		Celera
Cytogenetic Map	21	q22.3	NCBI
HuRef	21	32,055,824 - 32,079,809 (-)	NCBI		HuRef
CHM1_1	21	46,244,614 - 46,268,649 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	21	43,627,968 - 43,651,850 (-)	NCBI		T2T-CHM13v2.0

Pofut2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	77,095,056 - 77,105,420 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	77,095,052 - 77,105,409 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	77,259,081 - 77,269,586 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	77,259,218 - 77,269,575 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	76,722,045 - 76,732,331 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	76,703,016 - 76,713,302 (+)	NCBI		MGSCv36	mm8
Celera	10	78,303,122 - 78,313,408 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Pofut2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	11,366,636 - 11,378,252 (-)	NCBI		GRCr8
mRatBN7.2	20	11,367,073 - 11,377,788 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	11,367,096 - 11,377,743 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	12,063,353 - 12,074,197 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	11,424,338 - 11,435,182 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	11,896,070 - 11,906,914 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	12,117,811 - 12,128,747 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	12,117,811 - 12,128,747 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	14,281,734 - 14,293,273 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	11,763,519 - 11,774,234 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	11,763,761 - 11,774,702 (-)	NCBI
Celera	20	12,869,042 - 12,879,695 (-)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

POFUT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	41,325,621 - 41,347,850 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	36,195,733 - 36,217,956 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	31,572,645 - 31,594,027 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	44,855,437 - 44,876,862 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	44,855,437 - 44,876,862 (-)	Ensembl	panpan1.1		panPan2

POFUT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	38,813,252 - 38,821,656 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	38,813,255 - 38,818,734 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	38,011,321 - 38,020,838 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	38,419,017 - 38,428,528 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	38,419,017 - 38,428,746 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	38,281,541 - 38,291,629 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	38,243,013 - 38,252,458 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	38,756,782 - 38,766,883 (-)	NCBI		UU_Cfam_GSD_1.0

Pofut2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	38,093,845 - 38,106,139 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936778	1,023,992 - 1,039,135 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936778	1,024,066 - 1,036,365 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POFUT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	13	207,801,101 - 207,818,138 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	217,902,861 - 217,919,990 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POFUT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	88,949,293 - 88,973,007 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	17,131,714 - 17,154,705 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pofut2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	30,644,681 - 30,658,909 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	30,648,423 - 30,658,862 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005375911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01007884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01098842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000021924 ⟹ ENSCLAP00000021721

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955407	41,972,717 - 41,984,095 (-)	Ensembl

RefSeq Acc Id:

XM_005375911 ⟹ XP_005375968

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955407	41,972,833 - 41,984,095 (-)	NCBI

Sequence:

show sequence

GCGCTTCCGGGACGGGCTCCGGGCCGCCGGAATTGCGTGGCCGCCAGGGCCATGGCGGCGCTCG
CCGGCCTCTGTCTGCTGCTCCAGGCAGCGTCCTGGCCGCTGATCTCGGCCTCGGGCGAGGAGTT
CTGGCCCGGCCAGTCGGCCGCCGACATCCTGTCGGGAGTGGCGTCCCGCAGACGGTACCTCCTG
TACGACGTCAACCCCCCAGAAGGCTTCAACCTCCGCAGGGATGTCTATATCCGTGTGGCCTCCC
TGCTGAAGACCCTGCTGAAGACCGAGGAGTGGGTGCTCGTCCTGCCCCCGTGGGGCCGCCTCTA
TCACTGGCAGAGTCCCGACATCCACCAGGTCCGGATCCCGTGGTCTGAGTTTTTCGATCTTCCG
AGTCTCAACAAGAACATCCCTGTCATTGAGTATGAGCAGTTCATTGCAGAGTCTGGAGGGCCCT
TCATCGACCAGGTGTACGTCCTGCAGGGTTATGCAGAAGGCTGGAAGGAGGGCACCTGGGAAGA
GAAGGTGGACGCACGGCCCTGCATTGACCCACTGCTCTACTCCCAGGACAAGCATGAGTACTAC
AGGGGCTGGTTCTGGGGCTACGAAGAAACCCGGGGCTTGAACGTCTCCTGCCTCTCCGTGCAAG
GCTCAGCCTCTGTGGTGGCCCCTGTGCTGCTGAAGAACACGTCGGCCCGGTCTGTGATGTTGGA
CAGAGCTGAAAACCTGCTTCACGACCACTATGGAGGAAAAGAATACTGGGATACCCGGCGGAGT
ATGGTGTTTGCCAAGCACCTGCGGGTGGCGGGAGACGAGTTTCGGAGCAAGTTCCTCAACTCCA
GTGACGCTGTGGACGGTGCCCCCATGGAAGAGGACTGGACAAAGCTGAAGGTCAAGCTGGGCTC
CTCACTCGGAGGTCCATACCTCGCCGTCCACCTGCGGAGGAAGGACTTTATCTGGGGCCACAGG
GACGACGTGCCCAGCCTGGAGGGTGCTGCCAGGAAGATCCGTAGCCTCATGACGGTGCACCAGC
TGCCCAGGGTGTTCGTGGCCACAGATGCCATCAGGAAGGAACAGGAAGACCTGAAGAGGCTGCT
GCCTGAGATGGTGAGGTTTGAACCCACCTGGGAGGAGCTGGAGCTGTACAAGGATGGCGGCGTC
GCCATCATCGATCAGTGGATTTGCGCACACGCCAGGTTTTTCATCGGCACATCGGTTTCCACAT
TTTCTTTTCGGATTCATGAGGAAAGAGAAATCTTGGGGTTTGATCCCAAGACAACATACAACCG
GTTTTGTGGTGACCAGGAGAAAGCGTGTGAGCAGCCTACCCACTGGAAGATCGCATACTGAGGG
CGCCCGTGTGCATCAGCTGCCGGGAACAAGCGCAGAGGCGCCCCACTCGCGGGCATGACACGTC
CAGGTGGTGCCCTGGCCCAGCGCGTCCTTCACCTAAGGTCACGTCTTAGCTGTGTGCTGACTAC
AAAATGCAGGAGCCTCTCAGCCCGTTGTGGGTGGGATGAGGATGGTGACAGTGGCCACCCTCGC
AGGTGGCTGCAGAGTTGAGGGCGACCTCAGAGTGTGCAGCTCTGCTATCTCCTGGGGTGACGAT
GTGAGGCTTGGCCACCCTATACTCGGCAAGCACCAGGGAGAGAGAGGTGACAGGCCTCTCACAC
CCTCCTCTGTCCACACGGGAAACACGGTGTCAACTCCACTGGGGGACACAGTGGGCTTCCAGGC
CCCCTGCTAACTGCCAAGAAGTGAGAAGCGATAGTCAAACCAACTTTGGAGGCTGCGTCAGAGA
TTACCTGCTTCACCAGTAGCTTTGTCCCAGCTCACAAGACTCCTCTTCCAGTGTTCACTGCCGC
CGGTAAGGATACTTGCAGGCCGCTGAAGTACAGTGGGCAGGGCCGGGGCAGCCTCGGGCCTGTG
GTCACTATGCCCCTGCAGGACTTCACTGTGGTGTAATGCACTGCACAGCCACTTCCTGGCCCAC
TGGTGACACAGTAGCACCCACGCCTTCCCTGTGCAGAGCTGGTGAACCCTTGTGTCCCCTCCCC
AAGCACCGGCAGGACCTCCAAGTAGGTCACTTAGGCTGCCAGGTGGAGTGATCACTATTTATTC
TTTTCCATTTGTACATTCAAATATTAATGAAATAAATTTTCTAGAAAGCTGTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005375968	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021721
	ENSCLAP00000021721.1

RefSeq Acc Id:

XP_005375968 ⟸ XM_005375911

- UniProtKB:

A0A8C2W1Q5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAALAGLCLLLQAASWPLISASGEEFWPGQSAADILSGVASRRRYLLYDVNPPEGFNLRRDVYI
RVASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYEQFIAE
SGGPFIDQVYVLQGYAEGWKEGTWEEKVDARPCIDPLLYSQDKHEYYRGWFWGYEETRGLNVSC
LSVQGSASVVAPVLLKNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFAKHLRVAGDEFRSK
FLNSSDAVDGAPMEEDWTKLKVKLGSSLGGPYLAVHLRRKDFIWGHRDDVPSLEGAARKIRSLM
TVHQLPRVFVATDAIRKEQEDLKRLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARFFIGT
SVSTFSFRIHEEREILGFDPKTTYNRFCGDQEKACEQPTHWKIAY

hide sequence

RefSeq Acc Id:

ENSCLAP00000021721 ⟸ ENSCLAT00000021924

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014869	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021924	ENTREZGENE
	ENSCLAT00000021924.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.11340	UniProtKB/TrEMBL
	3.40.50.11350	UniProtKB/TrEMBL
InterPro	GDP-Fuc_O-FucTrfase	UniProtKB/TrEMBL
	OFUT2-like	UniProtKB/TrEMBL
NCBI Gene	Pofut2	ENTREZGENE
PANTHER	GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2	UniProtKB/TrEMBL
	PTHR13398	UniProtKB/TrEMBL
Pfam	O-FucT	UniProtKB/TrEMBL
UniProt	A0A8C2W1Q5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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