Nthl1 (nth like DNA glycosylase 1)

Gene: Nthl1 (nth like DNA glycosylase 1) Chinchilla lanigera

Analyze

Symbol:

Nthl1

Name:

nth like DNA glycosylase 1

RGD ID:

8920260

Description:

ENCODES a protein that exhibits class I DNA-(apurinic or apyrimidinic site) endonuclease activity (ortholog); damaged DNA binding (ortholog); DNA N-glycosylase activity (ortholog); INVOLVED IN base-excision repair, AP site formation (ortholog); nucleotide-excision repair (ortholog); ASSOCIATED WITH Acute Hepatitis (ortholog); epilepsy (ortholog); familial adenomatous polyposis (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

endonuclease III-like protein 1; nth endonuclease III-like 1; nth-like DNA glycosylase 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,217,019 - 15,223,272 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	15,210,799 - 15,223,272 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Hepatitis (ISO)

epilepsy (ISO)

familial adenomatous polyposis (ISO)

familial adenomatous polyposis 3 (ISO)

Hereditary Neoplastic Syndromes (ISO)

idiopathic generalized epilepsy (ISO)

lymphangioleiomyomatosis (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

tuberous sclerosis 2 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

base-excision repair, AP site formation (ISO)

nucleotide-excision repair (ISO)

Cellular Component

mitochondrion (ISO)

nucleus (ISO)

Molecular Function

class I DNA-(apurinic or apyrimidinic site) endonuclease activity (ISO)

damaged DNA binding (ISO)

DNA N-glycosylase activity (ISO)

DNA-(apurinic or apyrimidinic site) endonuclease activity (ISO)

double-stranded DNA binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Nthl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,217,019 - 15,223,272 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	15,210,799 - 15,223,272 (+)	NCBI	ChiLan1.0	ChiLan1.0

NTHL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	2,039,820 - 2,047,834 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	2,039,815 - 2,047,866 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	2,089,821 - 2,097,835 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	2,029,817 - 2,037,868 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	2,029,816 - 2,037,868	NCBI
Celera	16	2,301,923 - 2,309,974 (-)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	2,014,043 - 2,022,132 (-)	NCBI		HuRef
CHM1_1	16	2,089,796 - 2,097,842 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	2,059,629 - 2,067,643 (-)	NCBI		T2T-CHM13v2.0

Nthl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	24,851,656 - 24,857,812 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	24,851,654 - 24,857,811 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	24,632,680 - 24,638,838 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	24,632,680 - 24,638,837 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	24,769,627 - 24,775,783 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	24,360,310 - 24,366,437 (+)	NCBI		MGSCv36	mm8
Celera	17	25,155,083 - 25,161,227 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.42	NCBI

Nthl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	14,160,334 - 14,166,502 (+)	NCBI		GRCr8
mRatBN7.2	10	13,655,791 - 13,661,958 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	13,655,785 - 13,661,957 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	18,402,559 - 18,408,752 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	17,891,405 - 17,897,598 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	13,390,604 - 13,396,797 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	13,996,660 - 14,002,827 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	13,996,645 - 14,002,910 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	13,813,645 - 13,819,807 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	13,883,284 - 13,889,790 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	13,883,284 - 13,889,789 (+)	NCBI
Celera	10	13,335,808 - 13,342,040 (+)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

NTHL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	2,298,565 - 2,306,762 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	6,080,263 - 6,088,450 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	655,433 - 663,521 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	2,127,858 - 2,135,656 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	2,127,858 - 2,135,656 (-)	Ensembl	panpan1.1		panPan2

NTHL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	38,899,144 - 38,904,637 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	38,899,126 - 38,905,622 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,137,884 - 40,143,376 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,207,235 - 39,212,727 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,207,226 - 39,212,603 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	38,892,037 - 38,897,529 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	38,864,355 - 38,869,847 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,343,154 - 39,348,649 (+)	NCBI		UU_Cfam_GSD_1.0

Nthl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,709,140 - 104,716,032 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	1,993,443 - 2,000,333 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	1,993,443 - 2,000,323 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NTHL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	39,935,475 - 39,941,712 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	39,935,619 - 39,941,718 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	42,239,826 - 42,245,913 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NTHL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	1,936,415 - 1,946,468 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	1,936,524 - 1,946,434 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	29,119,815 - 29,128,253 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nthl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	202,988 - 209,289 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624913	203,065 - 209,758 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005391465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005391466	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013517663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01037860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01155734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000017384 ⟹ ENSCLAP00000017215

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955442	15,217,019 - 15,223,272 (+)	Ensembl

RefSeq Acc Id:

XM_005391465 ⟹ XP_005391522

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955442	15,217,018 - 15,223,272 (+)	NCBI

Sequence:

show sequence

GTACTGAACACGTGACGGGCCGCCTGGGAGGCTGGAACGTGTAGTCGGCAGCGTCAGGCATGAA
GGCGGCGGCGGCAGCGGCGGCGAGGATGGTGACTCGCAGCCAGAGCCGCGCAACCGGGTTTGGG
TCGTTAGGAAATGGGGAAGAGCCAGTGCCACCCGGGAACGGAGAGGTGGCTTCAGAAGGAAGAA
AAAATCACAGGCCTATCAAGCGACAGCGGAAGGCACAGAGACTACATGTGGCCTATGAGGACTC
AGATGCTGAGAAAAGTAAGGGGACTGACCCTCTTGTGACCGCCTGGGAGCCACAGGACTGGAAG
CAGCAGCTAGCCAATATCCGCACCATGAGGAGCAGGAAGGATGCACCCGTGGACCAACTGGGGG
TTGAGCACTGCTATGACCCCAGTGTCCCCCCAAAGCAGGTACAGAGGTATCAGGTGCTGCTGTC
CCTGATGCTTTCCAGCCAGACCAAAGACCAGGTGACAGCAGGCGCCATGCAACGACTTCGGGCC
CGGGGCCTGACGGTAGACAGCATCCTGCAGACAGATGACAAGACGCTGGGCGAGCTCATCTACC
CTGTGGGATTTTGGAGGAGCAAGGTAAAGTTCATCAAGCAGACGAGTGCCATCCTGCAACAGCG
CTACAACGGGGACATCCCAGCCTCTCTGGCAGAGCTGGTGGCACTGCCAGGCGTTGGGCCCAAG
ATGGCGTACTTAGCTATGGCGGTGGCCTGGGGCACCGTGTCAGGAATAGCTGTGGACACACACG
TGCATAGAATTGCAAATCGACTGAGGTGGACCAAGAAAATGACCAAATCCCCAGAGGAGACCCG
CGTTGCCCTAGAGGAGTGGCTGCCCAGGGAGCTGTGGAGTGAGATCAATGGGCTATTGGTGGGC
TTTGGCCAGCAGATCTGCCTGCCCATCCATCCTCGCTGCCAGACCTGCCTCAACCAGGCCCTTT
GCCCTTCCGCCCAGAGCTTCTAAGGGCGATGGGGTTTCAGCTTGGGTCTTGTTGTTGCTGTTAC
CTATGAAGTGCCTTTGGGGGAGAGCGGGGTTCACAATTTGGGTAATAAAGCTTGGGGATGGTTT
GCA

hide sequence

RefSeq Acc Id:

XM_005391466 ⟹ XP_005391523

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955442	15,217,019 - 15,223,272 (+)	NCBI

Sequence:

show sequence

TACTGAACACGTGACGGGCCGCCTGGGAGGCTGGAACGTGTAGTCGGCAGCGTCAGGCATGAAG
GCGGCGGCGGCAGCGGCGGCGAGGATGGTGACTCGCAGCCAGAGCCGCGCAACCGGGTTTGGGT
CGTTAGGAAATGGGGAAGAGCCAGTGCCACCCGGGAACGGAGAGGTGGCTTCAGAAGGAAGAAA
AAATCACAGGCCTATCAAGCGACAGCGGAAGGCACAGAGACTACATGTGGCCTATGAGGACTCA
GATGCTGAGAAAAGTAAGGGGACTGACCCTCTTGTGACCGCCTGGGAGCCACAGGACTGGAAGC
AGCAGCTAGCCAATATCCGCACCATGAGGAGCAGGAAGGATGCACCCGTGGACCAACTGGGGGT
TGAGCACTGCTATGACCCCAGTGTCCCCCCAAAGGTACAGAGGTATCAGGTGCTGCTGTCCCTG
ATGCTTTCCAGCCAGACCAAAGACCAGGTGACAGCAGGCGCCATGCAACGACTTCGGGCCCGGG
GCCTGACGGTAGACAGCATCCTGCAGACAGATGACAAGACGCTGGGCGAGCTCATCTACCCTGT
GGGATTTTGGAGGAGCAAGGTAAAGTTCATCAAGCAGACGAGTGCCATCCTGCAACAGCGCTAC
AACGGGGACATCCCAGCCTCTCTGGCAGAGCTGGTGGCACTGCCAGGCGTTGGGCCCAAGATGG
CGTACTTAGCTATGGCGGTGGCCTGGGGCACCGTGTCAGGAATAGCTGTGGACACACACGTGCA
TAGAATTGCAAATCGACTGAGGTGGACCAAGAAAATGACCAAATCCCCAGAGGAGACCCGCGTT
GCCCTAGAGGAGTGGCTGCCCAGGGAGCTGTGGAGTGAGATCAATGGGCTATTGGTGGGCTTTG
GCCAGCAGATCTGCCTGCCCATCCATCCTCGCTGCCAGACCTGCCTCAACCAGGCCCTTTGCCC
TTCCGCCCAGAGCTTCTAAGGGCGATGGGGTTTCAGCTTGGGTCTTGTTGTTGCTGTTACCTAT
GAAGTGCCTTTGGGGGAGAGCGGGGTTCACAATTTGGGTAATAAAGCTTGGGGATGGTTTGCA

hide sequence

RefSeq Acc Id:

XM_013517663 ⟹ XP_013373117

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955442	15,210,799 - 15,223,272 (+)	NCBI

Sequence:

show sequence

GAGAAGAGGACAGTAGTTTGCTGAGCAGCCAAGACTATACCTTCTCCTCACCTCCTCCTCAGCA
GAGTCTGAATCCCACTACTGCTGAGAAGCATATTATCAGTCCCCTTGCAGTCACAGGCAGGCCA
CTCATGGTACCCGAGAAGACTCAGCAGGAGCCTACACAGGGACCATGCCTGGACATTCCCAAAC
TGCCTGAGGGTCAGAGCTGGGTGGCAGTAGGACTGTGCAGTTCATACTCAGGCTGGACTCCCTT
TGCAAGCGATACACACATTACGAGGTGGACGTTCAGGAAAGCCATGTTCAGGAAACAGGTTCCT
GGGTATCCGCATTACCCCAAGAGTTTCTGGAAGGAGACATATAACATGCACGGCAGCCAGCCTC
AGACAGAAACCTGACAGCAGCTGTCAGCACCCCTGCTGGGACAGATCTGGACCTCACAGCAGCA
AAATCCCACTCAGATTTACTTCTTCCTCCTTCCTCTTCCCACAACAGGGACATGAAGTCTGGAG
TCTGACCAAAATGTCTCACTGTCAAGGTACAGGAGGTCAACCAACAGTGGTGAGAACTCAGACT
GGGCTCAGACAGGACACTCTGGGCGACATGGGTTAACAATATCCTCTCCCAACAACAGAAAAGC
TACCACCCACCCACTTCAAAGACACCTTCAAGGTCTATTTCCTAGACACTCTGAGCCAGCAGGT
CTGGAGTAAAGTCCAAGAGCTGCATCCTGAAAGAACTCCTTGAAGATCCTGAAGGAAGAAAAAA
TCACAGGCCTATCAAGCGACAGCGGAAGGCACAGAGACTACATGTGGCCTATGAGGACTCAGAT
GCTGAGAAAAGTAAGGGGACTGACCCTCTTGTGACCGCCTGGGAGCCACAGGACTGGAAGCAGC
AGCTAGCCAATATCCGCACCATGAGGAGCAGGAAGGATGCACCCGTGGACCAACTGGGGGTTGA
GCACTGCTATGACCCCAGTGTCCCCCCAAAGCAGGTACAGAGGTATCAGGTGCTGCTGTCCCTG
ATGCTTTCCAGCCAGACCAAAGACCAGGTGACAGCAGGCGCCATGCAACGACTTCGGGCCCGGG
GCCTGACGGTAGACAGCATCCTGCAGACAGATGACAAGACGCTGGGCGAGCTCATCTACCCTGT
GGGATTTTGGAGGAGCAAGGTAAAGTTCATCAAGCAGACGAGTGCCATCCTGCAACAGCGCTAC
AACGGGGACATCCCAGCCTCTCTGGCAGAGCTGGTGGCACTGCCAGGCGTTGGGCCCAAGATGG
CGTACTTAGCTATGGCGGTGGCCTGGGGCACCGTGTCAGGAATAGCTGTGGACACACACGTGCA
TAGAATTGCAAATCGACTGAGGTGGACCAAGAAAATGACCAAATCCCCAGAGGAGACCCGCGTT
GCCCTAGAGGAGTGGCTGCCCAGGGAGCTGTGGAGTGAGATCAATGGGCTATTGGTGGGCTTTG
GCCAGCAGATCTGCCTGCCCATCCATCCTCGCTGCCAGACCTGCCTCAACCAGGCCCTTTGCCC
TTCCGCCCAGAGCTTCTAAGGGCGATGGGGTTTCAGCTTGGGTCTTGTTGTTGCTGTTACCTAT
GAAGTGCCTTTGGGGGAGAGCGGGGTTCACAATTTGGGTAATAAAGCTTGGGGATGGTTTGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005391522	(Get FASTA)	NCBI Sequence Viewer
	XP_005391523	(Get FASTA)	NCBI Sequence Viewer
	XP_013373117	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000017215
	ENSCLAP00000017215.1

RefSeq Acc Id:

XP_005391522 ⟸ XM_005391465

- Peptide Label:

isoform X1

- Sequence:

show sequence

MKAAAAAAARMVTRSQSRATGFGSLGNGEEPVPPGNGEVASEGRKNHRPIKRQRKAQRLHVAYE
DSDAEKSKGTDPLVTAWEPQDWKQQLANIRTMRSRKDAPVDQLGVEHCYDPSVPPKQVQRYQVL
LSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDKTLGELIYPVGFWRSKVKFIKQTSAILQ
QRYNGDIPASLAELVALPGVGPKMAYLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKMTKSPEE
TRVALEEWLPRELWSEINGLLVGFGQQICLPIHPRCQTCLNQALCPSAQSF

hide sequence

RefSeq Acc Id:	XP_005391523 ⟸ XM_005391466
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2VTB7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKAAAAAAARMVTRSQSRATGFGSLGNGEEPVPPGNGEVASEGRKNHRPIKRQRKAQRLHVAYE DSDAEKSKGTDPLVTAWEPQDWKQQLANIRTMRSRKDAPVDQLGVEHCYDPSVPPKVQRYQVLL SLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDKTLGELIYPVGFWRSKVKFIKQTSAILQQ RYNGDIPASLAELVALPGVGPKMAYLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKMTKSPEET RVALEEWLPRELWSEINGLLVGFGQQICLPIHPRCQTCLNQALCPSAQSF hide sequence

RefSeq Acc Id:

XP_013373117 ⟸ XM_013517663

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRSRKDAPVDQLGVEHCYDPSVPPKQVQRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSI
LQTDDKTLGELIYPVGFWRSKVKFIKQTSAILQQRYNGDIPASLAELVALPGVGPKMAYLAMAV
AWGTVSGIAVDTHVHRIANRLRWTKKMTKSPEETRVALEEWLPRELWSEINGLLVGFGQQICLP
IHPRCQTCLNQALCPSAQSF

hide sequence

RefSeq Acc Id:

ENSCLAP00000017215 ⟸ ENSCLAT00000017384

Protein Domains

HhH-GPD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011819	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000017384	ENTREZGENE
	ENSCLAT00000017384.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1670.10	UniProtKB/TrEMBL
InterPro	DNA_glycosylase	UniProtKB/TrEMBL
	Endonuclease-III-like_CS2	UniProtKB/TrEMBL
	Endonuclease3_FeS-loop_motif	UniProtKB/TrEMBL
	HhH-GPD_domain	UniProtKB/TrEMBL
	HhH_base_excis_C	UniProtKB/TrEMBL
	HhH_motif	UniProtKB/TrEMBL
	NTH1	UniProtKB/TrEMBL
NCBI Gene	Nthl1	ENTREZGENE
PANTHER	ENDONUCLEASE III-LIKE PROTEIN 1	UniProtKB/TrEMBL
	ENDONUCLEASE III-LIKE PROTEIN 1	UniProtKB/TrEMBL
Pfam	HHH	UniProtKB/TrEMBL
	HhH-GPD	UniProtKB/TrEMBL
PROSITE	ENDONUCLEASE_III_2	UniProtKB/TrEMBL
SMART	ENDO3c	UniProtKB/TrEMBL
	FES	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48150	UniProtKB/TrEMBL
UniProt	A0A8C2VTB7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-26	Nthl1	nth like DNA glycosylase 1		nth-like DNA glycosylase 1	Symbol and/or name change	5135510	APPROVED
2015-08-25	Nthl1	nth-like DNA glycosylase 1		nth endonuclease III-like 1 (E. coli)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM