Adam28 (ADAM metallopeptidase domain 28)

Gene: Adam28 (ADAM metallopeptidase domain 28) Chinchilla lanigera

Analyze

Symbol:

Adam28

Name:

ADAM metallopeptidase domain 28

RGD ID:

8919122

Description:

ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); metallopeptidase activity (ortholog); ASSOCIATED WITH asbestos-related lung carcinoma (ortholog); breast cancer (ortholog); breast carcinoma (ortholog); FOUND IN cell surface (ortholog); mitochondrion (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

disintegrin and metalloproteinase domain-containing protein 28

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	47,319,382 - 47,409,380 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	47,304,711 - 47,409,369 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asbestos-related lung carcinoma (ISO)

breast cancer (ISO)

breast carcinoma (ISO)

colorectal cancer (ISO)

estrogen-receptor positive breast cancer (ISO)

genetic disease (ISO)

hereditary spastic paraplegia (ISO)

invasive ductal carcinoma (ISO)

liver cancer (ISO)

lung adenocarcinoma (ISO)

lung metastasis (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

Lymphatic Metastasis (ISO)

Prostatic Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cell surface (ISO)

mitochondrion (ISO)

plasma membrane (ISO)

Molecular Function

immunoglobulin receptor binding (ISO)

metallopeptidase activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Adam28
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	47,319,382 - 47,409,380 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	47,304,711 - 47,409,369 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADAM28
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	24,294,069 - 24,359,014 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	24,294,069 - 24,359,014 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	24,151,582 - 24,216,527 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	24,207,525 - 24,268,671 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	23,115,137 - 23,176,304 (+)	NCBI		Celera
Cytogenetic Map	8	p21.2	NCBI
HuRef	8	22,696,187 - 22,757,353 (+)	NCBI		HuRef
CHM1_1	8	24,353,747 - 24,414,881 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	24,569,171 - 24,634,154 (+)	NCBI		T2T-CHM13v2.0

Adam28
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	68,842,447 - 68,893,338 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	68,843,476 - 68,893,291 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	68,604,998 - 68,655,889 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	68,606,027 - 68,655,842 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	69,224,084 - 69,273,899 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	67,560,209 - 67,609,172 (-)	NCBI		MGSCv36	mm8
Celera	14	66,379,012 - 66,429,923 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	35.69	NCBI

Adam28
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	50,184,286 - 50,250,605 (-)	NCBI		GRCr8
mRatBN7.2	15	43,774,463 - 43,840,726 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	42,944,467 - 43,840,672 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	47,893,627 - 47,958,632 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	49,005,105 - 49,070,113 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	45,864,488 - 45,929,498 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	50,356,745 - 50,425,911 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	50,358,192 - 50,425,900 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	54,088,439 - 54,158,964 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	49,020,423 - 49,085,202 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	49,036,202 - 49,100,982 (-)	NCBI
Celera	15	43,474,975 - 43,539,804 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

ADAM28
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	42,796,292 - 42,863,608 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	18,523,249 - 18,602,127 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	23,549,892 - 23,623,859 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	20,474,820 - 20,540,955 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	20,474,029 - 20,540,692 (+)	Ensembl	panpan1.1		panPan2

ADAM28
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	33,092,645 - 33,147,791 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	33,092,628 - 33,264,710 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	33,677,242 - 33,732,321 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	33,298,789 - 33,353,872 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	33,299,274 - 33,470,021 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	33,246,937 - 33,302,028 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	33,103,486 - 33,158,752 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	33,261,650 - 33,316,886 (-)	NCBI		UU_Cfam_GSD_1.0

Adam28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	10,905,896 - 10,954,986 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	7,617,822 - 7,664,215 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	7,615,639 - 7,660,776 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAM28
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	8,375,212 - 8,438,615 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	8,375,169 - 8,438,622 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	9,418,095 - 9,481,491 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAM28
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	22,424,260 - 22,483,878 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	22,430,579 - 22,488,257 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	19,696,502 - 19,763,128 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adam28
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	19,432,817 - 19,497,686 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	19,427,871 - 19,499,510 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005373705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013514042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013514049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01002885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01002886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01002887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01002888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01002889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01020328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000023994 ⟹ ENSCLAP00000023768

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955403	47,319,382 - 47,409,380 (+)	Ensembl

RefSeq Acc Id:

XM_005373705 ⟹ XP_005373762

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	47,357,472 - 47,409,369 (+)	NCBI

Sequence:

show sequence

AATGAAGCAGGGAGTTTCACGGCGTCTCACTTCAGCGGAGGCAGGGGCAGAGCTGCAGCTCGGG
TGTGAGCCAGGGCAGGCCCGCGCTGCCGGAGGCCCCAGCATGTGGCAAGGGACTCTGCTGGTGC
TCATGCTCCTGCCATCTCCAGCTCCAGTAAATGCTATGAAAGAGCTCCCTCAGGCAAAGAACTA
TGAAGTTGTTTATCCAGTAAGACTTCATCCACTACATAAAAGAGAAGCCAAAGAACCAGAAAAA
CAGAAACAATTTGAACTTGAATTAAAGTATCAAATGACAGTGAATGGAAAAATTGCAGTGCTTT
ACTTGAAGAAAAACAAGAACCTTGTTGCTTCAAACTACACGGAAACATACTATAAACCCTCTGG
AGAAGAAGTCAGCACGAGCCCACAAATCATGGATAACTGTTACTATCAAGGATACATCATGAAT
GAAAACGTTTCTGATGCCAGCATCAGCACATGTAGGGGCCTAAGAGGCTACTTCAGTCAAGGAG
ACCAAAGGTATTTCATTGAGCCTTTGAGCTCCACACATCAGGATGAACAGGAGCACGCACTCTT
CAAGGATGAGCCCAGCGATAACCAGGCTAACAGCAGCTGTGGGATGGAGGATGTGCTATGGGTA
CAAGGATTCCACCAGAATGTGGTCTCACCTGCCACAAGACTGGTTGAATTAAATGGTCGGAAGA
TTCAGGATCATAGCAAATACATAGAATATTATTTGGTCCTGGATAATGGTGAGTTTAAAAAGTA
CAATGAAGATCTGGATGAAATAAGAAAGAGGGTGTTTGAGATGGCCAATTACATTAACATGCTT
TACAAAAAGCTCAATGCTCATGTGGCCTTAGTTGGGATGGAAATCTGGACAGATGAGGATAAGA
TAAAGATAACCCCAAATGCATCCTCTACTCTGGAAAACTTTTCTAAATGGAGAGGGAGTAATCT
CCTCAGAAGAAAGCACCATGATATTGCTCAGTTAATCTCCACAACAGACTTTTCTGGAGCAATG
GTGGGCCTTGCTTTCCTGTCTTCGATGTGCTCTCCGTACCACTCCGTTGGCATTGTTCAGGACC
ACAGCAGCAATCATCTTAGAGTTGCGGGGACGATGGCTCATGAGATGGGCCACAATCTTGGAAT
GATTCATGACTACACTGATTGCAAGTGCCCGTCCACAGTCTGCGTGATGAAGAAAACGATAAGC
TTCTATATACCCACAGATTTCAGTTCCTGTAGCCGCTCCAACTATGATAGATTCCTTGAAGATA
AATTATCAAATTGCCTCTTTAATGTCCCACTACCTACAGATATCATATCCACCCCATTCTGTGG
GAACCAGTTGGTAGAAGTGGGAGAGGACTGTGACTGCGGGACCCCCGAGGAATGTACCAACACT
TGCTGTGATGCTAAAACATGTAAAATCAAAGCAGGTTTTCAATGTGCATCAGGAGGATGCTGTG
AAAAATGCCAATTGAAAAAGGCTGGAACGGTGTGCAGATCAGCAAGACATGAGTGTGACCTGGC
CGAAATGTGTGATGGGAAATCCAGTCGCTGCCCTGATGACAGATTCAGGGTCAATGGCTTCCCT
TGTCAAAATGGAAAGGGCTACTGCTTGATGGGGGAGTGCCCTACACTGGAAGAGCAGTGCACGG
ACATGTGGGGCCCAGGAACCAAGGTTGCAGATGAATCATGCTACAAGAAGAATGAAGGTGGGTC
CAAGTATGGATACTGTCACATGGTGAATGACACCCACGTTCCCTGCAAAGCAAAAGACGTCATG
TGTGGGAAGCTCTTCTGTGAAGGTGGGTCAGGTGATTTGCGCTGGAAAGGATTTACAATATCTT
TCCTCACATGTAAACTGTTTGATCCTGAAGACAAAAGTCAAGGAGTAGACATGGTGGCCGATGG
AACCAAGTGTGGGCATAGCAAGGTGTGCATTAACGCAGAGTGTGTGGATATGGAGAGGATCTAC
AAGTCAGCCAACTGTTCCTCTAAGTGCAAAGGACATGCTGTGTGTGACCATGAGCTCCAGTGCC
GGTGCAAAGAAGGATGGGCCCCTCCCGACTGCGAGGATTCCTCCACAGTCTTCCACTTCTCCAT
CGTGGTCGGAGTGCTGTTCCCTGTGGCGGTCATCTTTGTGGTAGTTGCTGTGGTCCTATGTCAC
CAAGGTGTCAGGAGACAGCGGAAGAAAGCTCAAAGACCACTATGTGCCGCTGACCCCAGGCTAC
ACAAGCAGAAGAGTAAACTCCAGAAGATGAAGGCTGTCCAGCCCCAAGAGATCAGTCAAATGAA
GCTCCCTCTGTCTCCTCTGCCTGTAGAAGATGGCGAGCCTCCAGCTTATGTGCTAATTTCAAAG
CCTGATTTCCCACCACCACCAATTCCTACATCGGTATCTTCTTCCTTTTTGCTTCATAAAGACA
CAAAAGCACTTCCTTCCACTGTTATCAAAGATAAACCAATGTCTACACCTGAGGTCTCAAATTC
AAAAGTCTGAAGCATCAGTTAAGCAAAGACTGATGGCCAAATGCTCAAACTGGAAGGTTGGGCA
GACTGGATGGAAAAGAATCAAACATACTTGGTCACTACTGTGTGCTCTTGATACCAGCATATCC
TGATTCCTGTAATACTTTGAAGAGCTTAAATAAATTTTTTTCAAGAGAGATATTCTCCTAGAAA
TCTTTATGTTAATTTAAAATTTATTATCTCCATACTTATGATAACTCTGAAGAGACATCTATGA
ACTTTATATTTCTAATCAGCTTATTTTTCCCAAAATTCCCCTTTTTATTATGCTACTGCCTAAT
TATTTGGCTAGTTTAAACACCTTAATTTGCTCGTGTGATAGAAATTAATCCACTGTAGTGAAAG
AAAAGCAAAATAGAAATCACAGGAAACTGGAAGGGATGGAAGGAAAAACAAACCTTCATTATTG
TGCAGCAATATCTTGATCGTTTTAACTGTTAACTTGTCAAAATTAAAATCCTTAGGAGAAAATT
ATGTAAACACTCTGTCATCTAATGTATCTCTTTCTTATATCGTCTCCTGAGATTTTTATTAGCT
CTGTCATTTGTTGTTTTCCACA

hide sequence

RefSeq Acc Id:

XM_013514042 ⟹ XP_013369496

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	47,304,730 - 47,409,369 (+)	NCBI

Sequence:

show sequence

GAATGGTGAGATGAATATGTTTAAAGTGATAAGGGCTATTTTGCGGGGTATTAAGGGGCATTTT
CCTTTGCTGCAAGTGAATAACACAGATGAGGAAATTTGTAAAGAAAAGAGATTGATTGAGCTCA
TCATTGTGGAGGTCAAAGAGCATGCCAATGGCATCCGCTCAGCACCAAGGGAAGGCCATCCTGC
TTGATCATGACATGTAAATGCTATGAAAGAGCTCCCTCAGGCAAAGAACTATGAAGTTGTTTAT
CCAGTAAGACTTCATCCACTACATAAAAGAGAAGCCAAAGAACCAGAAAAACAGAAACAATTTG
AACTTGAATTAAAGTATCAAATGACAGTGAATGGAAAAATTGCAGTGCTTTACTTGAAGAAAAA
CAAGAACCTTGTTGCTTCAAACTACACGGAAACATACTATAAACCCTCTGGAGAAGAAGTCAGC
ACGAGCCCACAAATCATGGATAACTGTTACTATCAAGGATACATCATGAATGAAAACGTTTCTG
ATGCCAGCATCAGCACATGTAGGGGCCTAAGAGGCTACTTCAGTCAAGGAGACCAAAGGTATTT
CATTGAGCCTTTGAGCTCCACACATCAGGATGAACAGGAGCACGCACTCTTCAAGGATGAGCCC
AGCGATAACCAGGCTAACAGCAGCTGTGGGATGGAGGATGTGCTATGGGTACAAGGATTCCACC
AGAATGTGGTCTCACCTGCCACAAGACTGGTTGAATTAAATGGTCGGAAGATTCAGGATCATAG
CAAATACATAGAATATTATTTGGTCCTGGATAATGGTGAGTTTAAAAAGTACAATGAAGATCTG
GATGAAATAAGAAAGAGGGTGTTTGAGATGGCCAATTACATTAACATGCTTTACAAAAAGCTCA
ATGCTCATGTGGCCTTAGTTGGGATGGAAATCTGGACAGATGAGGATAAGATAAAGATAACCCC
AAATGCATCCTCTACTCTGGAAAACTTTTCTAAATGGAGAGGGAGTAATCTCCTCAGAAGAAAG
CACCATGATATTGCTCAGTTAATCTCCACAACAGACTTTTCTGGAGCAATGGTGGGCCTTGCTT
TCCTGTCTTCGATGTGCTCTCCGTACCACTCCGTTGGCATTGTTCAGGACCACAGCAGCAATCA
TCTTAGAGTTGCGGGGACGATGGCTCATGAGATGGGCCACAATCTTGGAATGATTCATGACTAC
ACTGATTGCAAGTGCCCGTCCACAGTCTGCGTGATGAAGAAAACGATAAGCTTCTATATACCCA
CAGATTTCAGTTCCTGTAGCCGCTCCAACTATGATAGATTCCTTGAAGATAAATTATCAAATTG
CCTCTTTAATGTCCCACTACCTACAGATATCATATCCACCCCATTCTGTGGGAACCAGTTGGTA
GAAGTGGGAGAGGACTGTGACTGCGGGACCCCCGAGGAATGTACCAACACTTGCTGTGATGCTA
AAACATGTAAAATCAAAGCAGGTTTTCAATGTGCATCAGGAGGATGCTGTGAAAAATGCCAATT
GAAAAAGGCTGGAACGGTGTGCAGATCAGCAAGACATGAGTGTGACCTGGCCGAAATGTGTGAT
GGGAAATCCAGTCGCTGCCCTGATGACAGATTCAGGGTCAATGGCTTCCCTTGTCAAAATGGAA
AGGGCTACTGCTTGATGGGGGAGTGCCCTACACTGGAAGAGCAGTGCACGGACATGTGGGGCCC
AGGAACCAAGGTTGCAGATGAATCATGCTACAAGAAGAATGAAGGTGGGTCCAAGTATGGATAC
TGTCACATGGTGAATGACACCCACGTTCCCTGCAAAGCAAAAGACGTCATGTGTGGGAAGCTCT
TCTGTGAAGGTGGGTCAGGTGATTTGCGCTGGAAAGGATTTACAATATCTTTCCTCACATGTAA
ACTGTTTGATCCTGAAGACAAAAGTCAAGGAGTAGACATGGTGGCCGATGGAACCAAGTGTGGG
CATAGCAAGGTGTGCATTAACGCAGAGTGTGTGGATATGGAGAGGATCTACAAGTCAGCCAACT
GTTCCTCTAAGTGCAAAGGACATGCTGTGTGTGACCATGAGCTCCAGTGCCGGTGCAAAGAAGG
ATGGGCCCCTCCCGACTGCGAGGATTCCTCCACAGTCTTCCACTTCTCCATCGTGGTCGGAGTG
CTGTTCCCTGTGGCGGTCATCTTTGTGGTAGTTGCTGTGGTCCTATGTCACCAAGGTGTCAGGA
GACAGCGGAAGAAAGCTCAAAGACCACTATGTGCCGCTGACCCCAGGCTACACAAGCAGAAGAG
TAAACTCCAGAAGATGAAGGCTGTCCAGCCCCAAGAGATCAGTCAAATGAAGCTCCCTCTGTCT
CCTCTGCCTGTAGAAGATGGCGAGCCTCCAGCTTATGTGCTAATTTCAAAGCCTGATTTCCCAC
CACCACCAATTCCTACATCGGTATCTTCTTCCTTTTTGCTTCATAAAGACACAAAAGCACTTCC
TTCCACTGTTATCAAAGATAAACCAATGTCTACACCTGAGGTCTCAAATTCAAAAGTCTGAAGC
ATCAGTTAAGCAAAGACTGATGGCCAAATGCTCAAACTGGAAGGTTGGGCAGACTGGATGGAAA
AGAATCAAACATACTTGGTCACTACTGTGTGCTCTTGATACCAGCATATCCTGATTCCTGTAAT
ACTTTGAAGAGCTTAAATAAATTTTTTTCAAGAGAGATATTCTCCTAGAAATCTTTATGTTAAT
TTAAAATTTATTATCTCCATACTTATGATAACTCTGAAGAGACATCTATGAACTTTATATTTCT
AATCAGCTTATTTTTCCCAAAATTCCCCTTTTTATTATGCTACTGCCTAATTATTTGGCTAGTT
TAAACACCTTAATTTGCTCGTGTGATAGAAATTAATCCACTGTAGTGAAAGAAAAGCAAAATAG
AAATCACAGGAAACTGGAAGGGATGGAAGGAAAAACAAACCTTCATTATTGTGCAGCAATATCT
TGATCGTTTTAACTGTTAACTTGTCAAAATTAAAATCCTTAGGAGAAAATTATGTAAACACTCT
GTCATCTAATGTATCTCTTTCTTATATCGTCTCCTGAGATTTTTATTAGCTCTGTCATTTGTTG
TTTTCCACA

hide sequence

RefSeq Acc Id:

XM_013514049 ⟹ XP_013369503

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	47,304,711 - 47,409,369 (+)	NCBI

Sequence:

show sequence

CTGCTTCAGCAAGTGGCACGAATGGGGCATTTTCCTTTGCTGCAAGTGAATAACACAGATGAGG
AAATTTGTAAAGAAAAGAGATTGATTGAGCTCATCATTGTGGAGGTCAAAGAGCATGCCAATGG
CATCCGCTCAGCACCAAGGGAAGGCCATCCTGCTTGATCATGACATGTAAATGCTATGAAAGAG
CTCCCTCAGGCAAAGAACTATGAAGTTGTTTATCCAGTAAGACTTCATCCACTACATAAAAGAG
AAGCCAAAGAACCAGAAAAACAGAAACAATTTGAACTTGAATTAAAGTATCAAATGACAGTGAA
TGGAAAAATTGCAGTGCTTTACTTGAAGAAAAACAAGAACCTTGTTGCTTCAAACTACACGGAA
ACATACTATAAACCCTCTGGAGAAGAAGTCAGCACGAGCCCACAAATCATGGATAACTGTTACT
ATCAAGGATACATCATGAATGAAAACGTTTCTGATGCCAGCATCAGCACATGTAGGGGCCTAAG
AGGCTACTTCAGTCAAGGAGACCAAAGGTATTTCATTGAGCCTTTGAGCTCCACACATCAGGAT
GAACAGGAGCACGCACTCTTCAAGGATGAGCCCAGCGATAACCAGGCTAACAGCAGCTGTGGGA
TGGAGGATGTGCTATGGGTACAAGGATTCCACCAGAATGTGGTCTCACCTGCCACAAGACTGGT
TGAATTAAATGGTCGGAAGATTCAGGATCATAGCAAATACATAGAATATTATTTGGTCCTGGAT
AATGGTGAGTTTAAAAAGTACAATGAAGATCTGGATGAAATAAGAAAGAGGGTGTTTGAGATGG
CCAATTACATTAACATGCTTTACAAAAAGCTCAATGCTCATGTGGCCTTAGTTGGGATGGAAAT
CTGGACAGATGAGGATAAGATAAAGATAACCCCAAATGCATCCTCTACTCTGGAAAACTTTTCT
AAATGGAGAGGGAGTAATCTCCTCAGAAGAAAGCACCATGATATTGCTCAGTTAATCTCCACAA
CAGACTTTTCTGGAGCAATGGTGGGCCTTGCTTTCCTGTCTTCGATGTGCTCTCCGTACCACTC
CGTTGGCATTGTTCAGGACCACAGCAGCAATCATCTTAGAGTTGCGGGGACGATGGCTCATGAG
ATGGGCCACAATCTTGGAATGATTCATGACTACACTGATTGCAAGTGCCCGTCCACAGTCTGCG
TGATGAAGAAAACGATAAGCTTCTATATACCCACAGATTTCAGTTCCTGTAGCCGCTCCAACTA
TGATAGATTCCTTGAAGATAAATTATCAAATTGCCTCTTTAATGTCCCACTACCTACAGATATC
ATATCCACCCCATTCTGTGGGAACCAGTTGGTAGAAGTGGGAGAGGACTGTGACTGCGGGACCC
CCGAGGAATGTACCAACACTTGCTGTGATGCTAAAACATGTAAAATCAAAGCAGGTTTTCAATG
TGCATCAGGAGGATGCTGTGAAAAATGCCAATTGAAAAAGGCTGGAACGGTGTGCAGATCAGCA
AGACATGAGTGTGACCTGGCCGAAATGTGTGATGGGAAATCCAGTCGCTGCCCTGATGACAGAT
TCAGGGTCAATGGCTTCCCTTGTCAAAATGGAAAGGGCTACTGCTTGATGGGGGAGTGCCCTAC
ACTGGAAGAGCAGTGCACGGACATGTGGGGCCCAGGAACCAAGGTTGCAGATGAATCATGCTAC
AAGAAGAATGAAGGTGGGTCCAAGTATGGATACTGTCACATGGTGAATGACACCCACGTTCCCT
GCAAAGCAAAAGACGTCATGTGTGGGAAGCTCTTCTGTGAAGGTGGGTCAGGTGATTTGCGCTG
GAAAGGATTTACAATATCTTTCCTCACATGTAAACTGTTTGATCCTGAAGACAAAAGTCAAGGA
GTAGACATGGTGGCCGATGGAACCAAGTGTGGGCATAGCAAGGTGTGCATTAACGCAGAGTGTG
TGGATATGGAGAGGATCTACAAGTCAGCCAACTGTTCCTCTAAGTGCAAAGGACATGCTGTGTG
TGACCATGAGCTCCAGTGCCGGTGCAAAGAAGGATGGGCCCCTCCCGACTGCGAGGATTCCTCC
ACAGTCTTCCACTTCTCCATCGTGGTCGGAGTGCTGTTCCCTGTGGCGGTCATCTTTGTGGTAG
TTGCTGTGGTCCTATGTCACCAAGGTGTCAGGAGACAGCGGAAGAAAGCTCAAAGACCACTATG
TGCCGCTGACCCCAGGCTACACAAGCAGAAGAGTAAACTCCAGAAGATGAAGGCTGTCCAGCCC
CAAGAGATCAGTCAAATGAAGCTCCCTCTGTCTCCTCTGCCTGTAGAAGATGGCGAGCCTCCAG
CTTATGTGCTAATTTCAAAGCCTGATTTCCCACCACCACCAATTCCTACATCGGTATCTTCTTC
CTTTTTGCTTCATAAAGACACAAAAGCACTTCCTTCCACTGTTATCAAAGATAAACCAATGTCT
ACACCTGAGGTCTCAAATTCAAAAGTCTGAAGCATCAGTTAAGCAAAGACTGATGGCCAAATGC
TCAAACTGGAAGGTTGGGCAGACTGGATGGAAAAGAATCAAACATACTTGGTCACTACTGTGTG
CTCTTGATACCAGCATATCCTGATTCCTGTAATACTTTGAAGAGCTTAAATAAATTTTTTTCAA
GAGAGATATTCTCCTAGAAATCTTTATGTTAATTTAAAATTTATTATCTCCATACTTATGATAA
CTCTGAAGAGACATCTATGAACTTTATATTTCTAATCAGCTTATTTTTCCCAAAATTCCCCTTT
TTATTATGCTACTGCCTAATTATTTGGCTAGTTTAAACACCTTAATTTGCTCGTGTGATAGAAA
TTAATCCACTGTAGTGAAAGAAAAGCAAAATAGAAATCACAGGAAACTGGAAGGGATGGAAGGA
AAAACAAACCTTCATTATTGTGCAGCAATATCTTGATCGTTTTAACTGTTAACTTGTCAAAATT
AAAATCCTTAGGAGAAAATTATGTAAACACTCTGTCATCTAATGTATCTCTTTCTTATATCGTC
TCCTGAGATTTTTATTAGCTCTGTCATTTGTTGTTTTCCACA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005373762	(Get FASTA)	NCBI Sequence Viewer
	XP_013369496	(Get FASTA)	NCBI Sequence Viewer
	XP_013369503	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000023768
	ENSCLAP00000023768.1

RefSeq Acc Id:

XP_005373762 ⟸ XM_005373705

- Peptide Label:

isoform X1

- Sequence:

show sequence

MKQGVSRRLTSAEAGAELQLGCEPGQARAAGGPSMWQGTLLVLMLLPSPAPVNAMKELPQAKNY
EVVYPVRLHPLHKREAKEPEKQKQFELELKYQMTVNGKIAVLYLKKNKNLVASNYTETYYKPSG
EEVSTSPQIMDNCYYQGYIMNENVSDASISTCRGLRGYFSQGDQRYFIEPLSSTHQDEQEHALF
KDEPSDNQANSSCGMEDVLWVQGFHQNVVSPATRLVELNGRKIQDHSKYIEYYLVLDNGEFKKY
NEDLDEIRKRVFEMANYINMLYKKLNAHVALVGMEIWTDEDKIKITPNASSTLENFSKWRGSNL
LRRKHHDIAQLISTTDFSGAMVGLAFLSSMCSPYHSVGIVQDHSSNHLRVAGTMAHEMGHNLGM
IHDYTDCKCPSTVCVMKKTISFYIPTDFSSCSRSNYDRFLEDKLSNCLFNVPLPTDIISTPFCG
NQLVEVGEDCDCGTPEECTNTCCDAKTCKIKAGFQCASGGCCEKCQLKKAGTVCRSARHECDLA
EMCDGKSSRCPDDRFRVNGFPCQNGKGYCLMGECPTLEEQCTDMWGPGTKVADESCYKKNEGGS
KYGYCHMVNDTHVPCKAKDVMCGKLFCEGGSGDLRWKGFTISFLTCKLFDPEDKSQGVDMVADG
TKCGHSKVCINAECVDMERIYKSANCSSKCKGHAVCDHELQCRCKEGWAPPDCEDSSTVFHFSI
VVGVLFPVAVIFVVVAVVLCHQGVRRQRKKAQRPLCAADPRLHKQKSKLQKMKAVQPQEISQMK
LPLSPLPVEDGEPPAYVLISKPDFPPPPIPTSVSSSFLLHKDTKALPSTVIKDKPMSTPEVSNS
KV

hide sequence

RefSeq Acc Id:	XP_013369503 ⟸ XM_013514049
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2YU94 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKELPQAKNYEVVYPVRLHPLHKREAKEPEKQKQFELELKYQMTVNGKIAVLYLKKNKNLVASN YTETYYKPSGEEVSTSPQIMDNCYYQGYIMNENVSDASISTCRGLRGYFSQGDQRYFIEPLSST HQDEQEHALFKDEPSDNQANSSCGMEDVLWVQGFHQNVVSPATRLVELNGRKIQDHSKYIEYYL VLDNGEFKKYNEDLDEIRKRVFEMANYINMLYKKLNAHVALVGMEIWTDEDKIKITPNASSTLE NFSKWRGSNLLRRKHHDIAQLISTTDFSGAMVGLAFLSSMCSPYHSVGIVQDHSSNHLRVAGTM AHEMGHNLGMIHDYTDCKCPSTVCVMKKTISFYIPTDFSSCSRSNYDRFLEDKLSNCLFNVPLP TDIISTPFCGNQLVEVGEDCDCGTPEECTNTCCDAKTCKIKAGFQCASGGCCEKCQLKKAGTVC RSARHECDLAEMCDGKSSRCPDDRFRVNGFPCQNGKGYCLMGECPTLEEQCTDMWGPGTKVADE SCYKKNEGGSKYGYCHMVNDTHVPCKAKDVMCGKLFCEGGSGDLRWKGFTISFLTCKLFDPEDK SQGVDMVADGTKCGHSKVCINAECVDMERIYKSANCSSKCKGHAVCDHELQCRCKEGWAPPDCE DSSTVFHFSIVVGVLFPVAVIFVVVAVVLCHQGVRRQRKKAQRPLCAADPRLHKQKSKLQKMKA VQPQEISQMKLPLSPLPVEDGEPPAYVLISKPDFPPPPIPTSVSSSFLLHKDTKALPSTVIKDK PMSTPEVSNSKV hide sequence

RefSeq Acc Id:	XP_013369496 ⟸ XM_013514042
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2YU94 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKELPQAKNYEVVYPVRLHPLHKREAKEPEKQKQFELELKYQMTVNGKIAVLYLKKNKNLVASN YTETYYKPSGEEVSTSPQIMDNCYYQGYIMNENVSDASISTCRGLRGYFSQGDQRYFIEPLSST HQDEQEHALFKDEPSDNQANSSCGMEDVLWVQGFHQNVVSPATRLVELNGRKIQDHSKYIEYYL VLDNGEFKKYNEDLDEIRKRVFEMANYINMLYKKLNAHVALVGMEIWTDEDKIKITPNASSTLE NFSKWRGSNLLRRKHHDIAQLISTTDFSGAMVGLAFLSSMCSPYHSVGIVQDHSSNHLRVAGTM AHEMGHNLGMIHDYTDCKCPSTVCVMKKTISFYIPTDFSSCSRSNYDRFLEDKLSNCLFNVPLP TDIISTPFCGNQLVEVGEDCDCGTPEECTNTCCDAKTCKIKAGFQCASGGCCEKCQLKKAGTVC RSARHECDLAEMCDGKSSRCPDDRFRVNGFPCQNGKGYCLMGECPTLEEQCTDMWGPGTKVADE SCYKKNEGGSKYGYCHMVNDTHVPCKAKDVMCGKLFCEGGSGDLRWKGFTISFLTCKLFDPEDK SQGVDMVADGTKCGHSKVCINAECVDMERIYKSANCSSKCKGHAVCDHELQCRCKEGWAPPDCE DSSTVFHFSIVVGVLFPVAVIFVVVAVVLCHQGVRRQRKKAQRPLCAADPRLHKQKSKLQKMKA VQPQEISQMKLPLSPLPVEDGEPPAYVLISKPDFPPPPIPTSVSSSFLLHKDTKALPSTVIKDK PMSTPEVSNSKV hide sequence

RefSeq Acc Id:

ENSCLAP00000023768 ⟸ ENSCLAT00000023994

Protein Domains

Disintegrin EGF-like Peptidase M12B

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000016310	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000023994	ENTREZGENE
	ENSCLAT00000023994.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.390.10	UniProtKB/TrEMBL
	4.10.70.10	UniProtKB/TrEMBL
InterPro	ADAM_Cys-rich	UniProtKB/TrEMBL
	Disintegrin_CS	UniProtKB/TrEMBL
	Disintegrin_dom	UniProtKB/TrEMBL
	Disintegrin_dom_sf	UniProtKB/TrEMBL
	EGF-like_dom	UniProtKB/TrEMBL
	MetalloPept_cat_dom_sf	UniProtKB/TrEMBL
	Peptidase_M12B	UniProtKB/TrEMBL
	Peptidase_M12B_N	UniProtKB/TrEMBL
	Reprolysin_adamalysin	UniProtKB/TrEMBL
NCBI Gene	Adam28	ENTREZGENE
PANTHER	ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN	UniProtKB/TrEMBL
	DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 28	UniProtKB/TrEMBL
Pfam	ADAM_CR	UniProtKB/TrEMBL
	Disintegrin	UniProtKB/TrEMBL
	Pep_M12B_propep	UniProtKB/TrEMBL
	Reprolysin	UniProtKB/TrEMBL
PRINTS	DISINTEGRIN	UniProtKB/TrEMBL
PROSITE	ADAM_MEPRO	UniProtKB/TrEMBL
	DISINTEGRIN_1	UniProtKB/TrEMBL
	DISINTEGRIN_2	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
SMART	ACR	UniProtKB/TrEMBL
	DISIN	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
	SSF57552	UniProtKB/TrEMBL
UniProt	A0A8C2YU94	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD