Glra3 (glycine receptor alpha 3) - Rat Genome Database

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Gene: Glra3 (glycine receptor alpha 3) Chinchilla lanigera
Analyze
Symbol: Glra3
Name: glycine receptor alpha 3
RGD ID: 8916921
Description: ENCODES a protein that exhibits extracellularly glycine-gated chloride channel activity (ortholog); glycine-gated chloride ion channel activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to ethanol (ortholog); cellular response to zinc ion (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); ovarian carcinoma (ortholog); FOUND IN glycine-gated chloride channel complex (ortholog); glycinergic synapse (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycine receptor subunit alpha-3; glycine receptor, alpha 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540332,304,178 - 32,445,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540332,304,178 - 32,445,135 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Glra3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540332,304,178 - 32,445,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540332,304,178 - 32,445,135 (+)NCBIChiLan1.0ChiLan1.0
GLRA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384174,636,920 - 174,829,247 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4174,636,920 - 174,829,247 (-)EnsemblGRCh38hg38GRCh38
GRCh374175,558,071 - 175,750,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364175,799,773 - 175,987,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 344175,938,939 - 176,125,108NCBI
Celera4172,892,194 - 173,079,664 (-)NCBICelera
Cytogenetic Map4q34.1NCBI
HuRef4171,312,700 - 171,499,685 (-)NCBIHuRef
CHM1_14175,539,655 - 175,726,888 (-)NCBICHM1_1
T2T-CHM13v2.04177,976,596 - 178,167,115 (-)NCBIT2T-CHM13v2.0
Glra3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39856,393,454 - 56,583,111 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl856,393,495 - 56,583,105 (+)EnsemblGRCm39 Ensembl
GRCm38855,940,418 - 56,130,070 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl855,940,460 - 56,130,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv37858,419,622 - 58,604,149 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36858,833,046 - 59,017,494 (+)NCBIMGSCv36mm8
Celera858,599,340 - 58,782,315 (+)NCBICelera
Cytogenetic Map8B2NCBI
cM Map829.69NCBI
Glra3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81639,210,534 - 39,857,332 (-)NCBIGRCr8
mRatBN7.21634,199,937 - 34,848,773 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1634,204,811 - 34,848,753 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1637,818,045 - 38,456,539 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01641,229,424 - 41,873,842 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01637,466,936 - 38,090,377 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01637,676,959 - 37,908,221 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1637,676,962 - 38,063,821 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01637,482,429 - 37,711,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41637,741,192 - 37,854,773 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11637,741,266 - 37,850,505 (+)NCBI
Celera1634,134,149 - 34,174,150 (-)NCBICelera
Cytogenetic Map16p11NCBI
GLRA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23172,396,653 - 172,579,346 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14172,777,048 - 172,959,364 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04166,865,061 - 167,045,844 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14179,103,608 - 179,279,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4179,083,211 - 179,279,232 (-)Ensemblpanpan1.1panPan2
GLRA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12525,098,280 - 25,305,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2525,131,250 - 25,305,027 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2525,783,206 - 25,957,841 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02525,261,937 - 25,469,138 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2525,294,466 - 25,469,586 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12525,195,872 - 25,403,554 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02525,098,834 - 25,305,712 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02525,250,704 - 25,458,008 (-)NCBIUU_Cfam_GSD_1.0
Glra3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494325,271,880 - 25,441,407 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365165,693,894 - 5,855,755 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365165,692,535 - 5,855,694 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1415,423,767 - 15,595,422 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11415,120,091 - 15,603,509 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21416,573,210 - 16,788,071 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLRA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17120,736,513 - 120,913,640 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037100,805,675 - 100,979,028 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glra3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247696,291,924 - 6,444,131 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247696,274,213 - 6,444,553 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000021464   ⟹   ENSCLAP00000021263
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540332,304,178 - 32,445,135 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021465   ⟹   ENSCLAP00000021264
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540332,304,192 - 32,444,816 (+)Ensembl
RefSeq Acc Id: XM_005373530   ⟹   XP_005373587
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540332,304,178 - 32,445,135 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373531   ⟹   XP_005373588
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540332,304,178 - 32,445,135 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373587 (Get FASTA)   NCBI Sequence Viewer  
  XP_005373588 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021263
  ENSCLAP00000021263.1
  ENSCLAP00000021264
  ENSCLAP00000021264.1
Reference Protein Sequences
RefSeq Acc Id: XP_005373587   ⟸   XM_005373530
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W2K2 (UniProtKB/TrEMBL),   A0A8C2VY83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005373588   ⟸   XM_005373531
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VY83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021263   ⟸   ENSCLAT00000021464
RefSeq Acc Id: ENSCLAP00000021264   ⟸   ENSCLAT00000021465
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014561 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021464 ENTREZGENE
  ENSCLAT00000021464.1 UniProtKB/TrEMBL
  ENSCLAT00000021465 ENTREZGENE
  ENSCLAT00000021465.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/TrEMBL
  Glycine_rcpt_A UniProtKB/TrEMBL
  Glycine_rcpt_A3 UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
NCBI Gene Glra3 ENTREZGENE
PANTHER GLYCINE RECEPTOR SUBUNIT ALPHA-3 UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS GABAARECEPTR UniProtKB/TrEMBL
  GLYRALPHA UniProtKB/TrEMBL
  GLYRALPHA3 UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A8C2VY83 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W2K2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Glra3  glycine receptor alpha 3    glycine receptor, alpha 3  Symbol and/or name change 5135510 APPROVED