Gpd1 (glycerol-3-phosphate dehydrogenase 1) - Rat Genome Database

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Gene: Gpd1 (glycerol-3-phosphate dehydrogenase 1) Chinchilla lanigera
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Symbol: Gpd1
Name: glycerol-3-phosphate dehydrogenase 1
RGD ID: 8913450
Description: ENCODES a protein that exhibits glycerol-3-phosphate dehydrogenase (quinone) activity (ortholog); glycerol-3-phosphate dehydrogenase [NAD(P)+] activity (ortholog); INVOLVED IN cellular response to cAMP (ortholog); cellular response to tumor necrosis factor (ortholog); gluconeogenesis (ortholog); PARTICIPATES IN D-glycericacidemia pathway; electron transport chain pathway; familial lipoprotein lipase deficiency pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); Hypertriglyceridemia, Transient Infantile (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547676,342 - 690,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547676,661 - 683,906 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gpd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955547676,342 - 690,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955547676,661 - 683,906 (+)NCBIChiLan1.0ChiLan1.0
GPD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381250,104,008 - 50,111,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1250,103,982 - 50,111,313 (+)EnsemblGRCh38hg38GRCh38
GRCh371250,497,791 - 50,505,096 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361248,784,068 - 48,791,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341248,784,067 - 48,791,360NCBI
Celera1249,293,286 - 49,300,582 (+)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1247,530,923 - 47,538,425 (+)NCBIHuRef
CHM1_11250,463,752 - 50,471,253 (+)NCBICHM1_1
T2T-CHM13v2.01250,067,090 - 50,074,395 (+)NCBIT2T-CHM13v2.0
Gpd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391599,615,468 - 99,622,895 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1599,615,396 - 99,622,886 (+)EnsemblGRCm39 Ensembl
GRCm381599,717,587 - 99,725,014 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1599,717,515 - 99,725,005 (+)EnsemblGRCm38mm10GRCm38
MGSCv371599,548,024 - 99,555,439 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361599,545,627 - 99,553,042 (+)NCBIMGSCv36mm8
Celera15101,873,405 - 101,880,780 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1556.13NCBI
Gpd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87132,722,982 - 132,730,373 (+)NCBIGRCr8
mRatBN7.27130,842,526 - 130,851,530 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7130,844,138 - 130,851,529 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7132,647,629 - 132,655,240 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07134,873,210 - 134,880,821 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07134,785,735 - 134,793,346 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07141,368,928 - 141,377,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7141,370,491 - 141,377,928 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X115,874,138 - 115,882,579 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47138,458,875 - 138,466,266 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17138,535,311 - 138,542,700 (+)NCBI
Celera7127,325,535 - 127,332,926 (+)NCBICelera
Cytogenetic Map7q36NCBI
GPD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21044,068,910 - 44,085,459 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11244,065,672 - 44,082,276 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01238,644,466 - 38,651,924 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11239,541,544 - 39,549,040 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1239,541,550 - 39,549,040 (-)Ensemblpanpan1.1panPan2
GPD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,614,878 - 4,622,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl274,614,864 - 4,621,922 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2741,636,151 - 41,643,304 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,663,998 - 4,671,137 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,664,000 - 4,671,090 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1274,628,876 - 4,636,009 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0274,619,676 - 4,625,555 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02742,031,192 - 42,038,340 (+)NCBIUU_Cfam_GSD_1.0
Gpd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494565,394,517 - 65,402,211 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365127,762,643 - 7,770,309 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365127,762,325 - 7,770,007 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl516,007,448 - 16,017,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1516,008,179 - 16,021,676 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2516,330,841 - 16,334,498 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11146,329,479 - 46,339,227 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1146,331,569 - 46,337,439 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037199,781,124 - 199,788,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248162,203,731 - 2,210,509 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248162,203,731 - 2,211,006 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000001886   ⟹   ENSCLAP00000001843
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955547676,342 - 690,403 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001887   ⟹   ENSCLAP00000001844
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955547676,342 - 684,734 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000001888   ⟹   ENSCLAP00000001845
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955547690,167 - 690,777 (+)Ensembl
RefSeq Acc Id: XM_005411873   ⟹   XP_005411930
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955547676,661 - 683,906 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005411930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001843.1
  ENSCLAP00000001844
  ENSCLAP00000001844.1
RefSeq Acc Id: XP_005411930   ⟸   XM_005411873
- UniProtKB: A0A8C2ULF4 (UniProtKB/TrEMBL),   A0A8C2UJK8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000001844   ⟸   ENSCLAT00000001887
Ensembl Acc Id: ENSCLAP00000001843   ⟸   ENSCLAT00000001886
Ensembl Acc Id: ENSCLAP00000001845   ⟸   ENSCLAT00000001888

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001367 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001886.1 UniProtKB/TrEMBL
  ENSCLAT00000001887 ENTREZGENE
  ENSCLAT00000001887.1 UniProtKB/TrEMBL
Gene3D-CATH N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/TrEMBL
  G3P_DH_NAD-dep UniProtKB/TrEMBL
  G3P_DH_NAD-dep_C UniProtKB/TrEMBL
  G3P_DH_NAD-dep_euk UniProtKB/TrEMBL
  G3P_DH_NAD-dep_N UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Gpd1 ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE DEHYDROGENASE UniProtKB/TrEMBL
  GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)], CYTOPLASMIC UniProtKB/TrEMBL
Pfam NAD_Gly3P_dh_C UniProtKB/TrEMBL
  NAD_Gly3P_dh_N UniProtKB/TrEMBL
PIRSF Glycerol-3-P_dh UniProtKB/TrEMBL
PRINTS GPDHDRGNASE UniProtKB/TrEMBL
PROSITE NAD_G3PDH UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2UJK8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2ULF4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Gpd1  glycerol-3-phosphate dehydrogenase 1    glycerol-3-phosphate dehydrogenase 1 (soluble)  Symbol and/or name change 5135510 APPROVED