Pls1 (plastin 1) - Rat Genome Database

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Gene: Pls1 (plastin 1) Chinchilla lanigera
Analyze
Symbol: Pls1
Name: plastin 1
RGD ID: 8913414
Description: INVOLVED IN auditory receptor cell stereocilium organization (ortholog); intestinal D-glucose absorption (ortholog); microvillus assembly (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness (ortholog); autosomal dominant nonsyndromic deafness 76 (ortholog); genetic disease (ortholog); FOUND IN brush border (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plastin-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555083,213,646 - 3,260,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555083,215,304 - 3,324,240 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pls1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555083,213,646 - 3,260,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555083,215,304 - 3,324,240 (-)NCBIChiLan1.0ChiLan1.0
PLS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383142,596,393 - 142,713,664 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3142,596,393 - 142,713,664 (+)EnsemblGRCh38hg38GRCh38
GRCh373142,315,235 - 142,432,506 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363143,825,034 - 143,915,191 (+)NCBINCBI36Build 36hg18NCBI36
Build 343143,825,041 - 143,915,199NCBI
Celera3140,738,741 - 140,856,000 (+)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3139,687,922 - 139,805,221 (+)NCBIHuRef
CHM1_13142,278,265 - 142,395,516 (+)NCBICHM1_1
T2T-CHM13v2.03145,343,653 - 145,460,901 (+)NCBIT2T-CHM13v2.0
Pls1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39995,634,695 - 95,727,359 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl995,634,695 - 95,727,364 (-)EnsemblGRCm39 Ensembl
GRCm38995,752,642 - 95,845,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl995,752,642 - 95,845,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37995,653,061 - 95,745,698 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36995,563,391 - 95,654,612 (-)NCBIMGSCv36mm8
Celera995,319,770 - 95,411,700 (-)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map950.22NCBI
Pls1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88105,196,312 - 105,306,252 (-)NCBIGRCr8
mRatBN7.2896,316,703 - 96,426,592 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl896,317,849 - 96,385,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8101,983,678 - 102,015,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08100,182,931 - 100,215,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0898,021,875 - 98,054,127 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08103,557,361 - 103,659,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8103,557,364 - 103,608,913 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08103,008,357 - 103,110,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48100,825,543 - 100,858,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18100,845,099 - 100,913,858 (-)NCBI
Celera895,763,631 - 95,795,453 (-)NCBICelera
Cytogenetic Map8q31NCBI
PLS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,490,165 - 140,623,025 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13140,494,897 - 140,627,757 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03139,629,825 - 139,747,080 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13147,221,909 - 147,338,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3147,289,205 - 147,338,600 (+)Ensemblpanpan1.1panPan2
PLS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12338,243,631 - 38,347,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2338,243,024 - 38,347,202 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2338,170,597 - 38,273,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02338,775,761 - 38,879,245 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2338,775,186 - 38,879,252 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12338,457,792 - 38,561,305 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02338,534,253 - 38,637,869 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02338,778,573 - 38,881,960 (+)NCBIUU_Cfam_GSD_1.0
Pls1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560277,466,080 - 77,583,189 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365404,205,844 - 4,323,120 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365404,205,871 - 4,323,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1383,308,007 - 83,434,128 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11383,307,692 - 83,434,133 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11547,919,807 - 48,031,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1547,919,823 - 48,003,805 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604120,854,232 - 20,965,494 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pls1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473019,163,783 - 19,302,222 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473019,164,360 - 19,302,369 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000001384   ⟹   ENSCLAP00000001342
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555083,213,646 - 3,260,554 (-)Ensembl
RefSeq Acc Id: XM_005407737   ⟹   XP_005407794
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555083,215,304 - 3,324,240 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013506262   ⟹   XP_013361716
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555083,220,993 - 3,324,240 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005407794 (Get FASTA)   NCBI Sequence Viewer  
  XP_013361716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001342
  ENSCLAP00000001342.1
RefSeq Acc Id: XP_005407794   ⟸   XM_005407737
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YIL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013361716   ⟸   XM_013506262
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000001342   ⟸   ENSCLAT00000001384
Protein Domains
Calponin-homology (CH)   EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001023 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001384 ENTREZGENE
  ENSCLAT00000001384.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Fimbrin/Plastin UniProtKB/TrEMBL
NCBI Gene Pls1 ENTREZGENE
PANTHER PTHR19961 UniProtKB/TrEMBL
  PTHR19961:SF27 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF47576 UniProtKB/TrEMBL
UniProt A0A8C2YIL2 ENTREZGENE, UniProtKB/TrEMBL