Cyria (CYFIP related Rac1 interactor A) - Rat Genome Database

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Gene: Cyria (CYFIP related Rac1 interactor A) Chinchilla lanigera
Analyze
Symbol: Cyria
Name: CYFIP related Rac1 interactor A (Ensembl:family with sequence similarity 49 member A)
RGD ID: 8912829
Description: ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); optic atrophy (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Fam49a; family with sequence similarity 49 member A; family with sequence similarity 49, member A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554879,545,639 - 9,636,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554879,545,639 - 9,636,183 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cyria
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554879,545,639 - 9,636,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554879,545,639 - 9,636,183 (-)NCBIChiLan1.0ChiLan1.0
CYRIA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38216,549,459 - 16,665,834 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl216,549,459 - 16,666,331 (-)EnsemblGRCh38hg38GRCh38
GRCh37216,730,727 - 16,847,102 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36216,597,382 - 16,710,580 (-)NCBINCBI36Build 36hg18NCBI36
Build 34216,655,528 - 16,768,724NCBI
Celera216,610,797 - 16,684,917 (-)NCBICelera
Cytogenetic Map2p24.2NCBI
HuRef216,505,559 - 16,621,967 (-)NCBIHuRef
CHM1_1216,660,180 - 16,734,676 (-)NCBICHM1_1
T2T-CHM13v2.0216,581,160 - 16,697,534 (-)NCBIT2T-CHM13v2.0
Cyria
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391212,312,136 - 12,430,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1212,312,140 - 12,430,966 (+)EnsemblGRCm39 Ensembl
GRCm381212,262,134 - 12,380,965 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1212,262,139 - 12,380,965 (+)EnsemblGRCm38mm10GRCm38
MGSCv371212,268,945 - 12,383,169 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361212,302,329 - 12,402,349 (+)NCBIMGSCv36mm8
Celera1212,607,335 - 12,720,232 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map125.63NCBI
Cyria
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8640,774,165 - 40,883,005 (+)NCBIGRCr8
mRatBN7.2635,045,208 - 35,150,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl635,045,208 - 35,150,668 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx635,346,881 - 35,452,349 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0635,661,507 - 35,766,973 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0635,123,999 - 35,229,298 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0637,555,167 - 37,661,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl637,555,182 - 37,665,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0650,682,248 - 50,788,038 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4635,830,497 - 35,936,574 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1635,875,817 - 35,940,028 (+)NCBI
Celera634,410,256 - 34,515,470 (+)NCBICelera
Cytogenetic Map6q15NCBI
CYRIA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212109,868,729 - 109,979,134 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A109,872,697 - 109,982,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A16,532,230 - 16,642,397 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A16,660,464 - 16,728,797 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A16,660,469 - 16,728,797 (-)Ensemblpanpan1.1panPan2
CYRIA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11712,208,319 - 12,311,775 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1712,211,494 - 12,270,152 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1712,154,659 - 12,258,045 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01712,338,751 - 12,442,231 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1712,338,753 - 12,442,261 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11712,196,811 - 12,300,249 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01712,208,493 - 12,311,876 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01712,234,516 - 12,296,349 (-)NCBIUU_Cfam_GSD_1.0
Cyria
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629256,700,509 - 56,758,417 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649314,081,148 - 14,139,780 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649314,081,178 - 14,139,054 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYRIA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3120,968,060 - 121,069,240 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13120,968,016 - 121,069,372 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23129,216,661 - 129,316,473 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYRIA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11490,990,100 - 91,076,449 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1490,961,862 - 91,074,560 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604521,141,542 - 21,251,039 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cyria
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624865343,954 - 429,915 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624865303,124 - 430,426 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000010433   ⟹   ENSCLAP00000010303
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554879,545,639 - 9,573,740 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000010434   ⟹   ENSCLAP00000010304
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554879,548,598 - 9,636,243 (-)Ensembl
RefSeq Acc Id: XM_005404447   ⟹   XP_005404504
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554879,545,639 - 9,636,183 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005404449   ⟹   XP_005404506
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554879,545,639 - 9,573,740 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504374   ⟹   XP_013359828
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554879,545,639 - 9,636,183 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404504 (Get FASTA)   NCBI Sequence Viewer  
  XP_005404506 (Get FASTA)   NCBI Sequence Viewer  
  XP_013359828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010303
  ENSCLAP00000010303.1
  ENSCLAP00000010304
  ENSCLAP00000010304.1
Reference Protein Sequences
RefSeq Acc Id: XP_005404504   ⟸   XM_005404447
- UniProtKB: A0A8C2V9V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404506   ⟸   XM_005404449
- UniProtKB: A0A8C2V9V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359828   ⟸   XM_013504374
- UniProtKB: A0A8C2V9V6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000010303   ⟸   ENSCLAT00000010433
RefSeq Acc Id: ENSCLAP00000010304   ⟸   ENSCLAT00000010434
Protein Domains
CYRIA/CYRIB Rac1 binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007123 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010433 ENTREZGENE
  ENSCLAT00000010433.1 UniProtKB/TrEMBL
  ENSCLAT00000010434 ENTREZGENE
  ENSCLAT00000010434.1 UniProtKB/TrEMBL
InterPro CYRI UniProtKB/TrEMBL
  CYRIA/CYRIB_Rac1-bd UniProtKB/TrEMBL
NCBI Gene Fam49a ENTREZGENE
PANTHER CYFIP-RELATED RAC1 INTERACTOR A UniProtKB/TrEMBL
  PTHR12422 UniProtKB/TrEMBL
Pfam DUF1394 UniProtKB/TrEMBL
UniProt A0A8C2V9V6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-26 Cyria  CYFIP related Rac1 interactor A  Fam49a  family with sequence similarity 49 member A  Symbol and/or name change 5135510 APPROVED
2016-08-16 Fam49a  family with sequence similarity 49 member A    family with sequence similarity 49, member A  Symbol and/or name change 5135510 APPROVED