Ano10 (anoctamin 10) - Rat Genome Database

Name: Ano10
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Ano10 (anoctamin 10) Chinchilla lanigera

Analyze

Symbol:

Ano10

Name:

anoctamin 10

RGD ID:

8909051

Description:

ENCODES a protein that exhibits calcium-activated cation channel activity (ortholog); intracellularly calcium-gated chloride channel activity (ortholog); phospholipid scramblase activity (ortholog); INVOLVED IN chloride transport (ortholog); monoatomic cation transport (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); autosomal recessive spinocerebellar ataxia 10 (ortholog); Chanarin-Dorfman syndrome (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

anoctamin-10

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANO10 (anoctamin 10)	NCBI	Ortholog
Mus musculus (house mouse):	Ano10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ano10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANO10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANO10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ano10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANO10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANO10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ano10 (anoctamin 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	27,572,561 - 27,696,269 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	27,572,561 - 27,682,099 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive cerebellar ataxia (ISO)

autosomal recessive spinocerebellar ataxia 10 (ISO)

Chanarin-Dorfman syndrome (ISO)

congenital muscular dystrophy-dystroglycanopathy type A8 (ISO)

genetic disease (ISO)

Spinocerebellar Ataxias (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transport (ISO)

monoatomic cation transport (ISO)

Cellular Component

intracellular membrane-bounded organelle (ISO)

plasma membrane (ISO)

Molecular Function

calcium-activated cation channel activity (ISO)

intracellularly calcium-gated chloride channel activity (ISO)

phospholipid scramblase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Ano10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	27,572,561 - 27,696,269 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	27,572,561 - 27,682,099 (+)	NCBI	ChiLan1.0	ChiLan1.0

ANO10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	43,365,848 - 43,691,594 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	43,354,859 - 43,691,594 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	43,407,340 - 43,733,086 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	43,382,822 - 43,638,564 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	43,345,314 - 43,601,240 (-)	NCBI		Celera
Cytogenetic Map	3	p22.1-p21.33	NCBI
HuRef	3	43,450,609 - 43,706,740 (-)	NCBI		HuRef
CHM1_1	3	43,357,824 - 43,613,711 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	43,381,160 - 43,707,182 (-)	NCBI		T2T-CHM13v2.0

Ano10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	122,004,958 - 122,123,440 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	122,004,940 - 122,123,489 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	122,175,874 - 122,294,444 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	122,175,874 - 122,294,423 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	122,084,997 - 122,203,492 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	122,024,577 - 122,143,072 (-)	NCBI		MGSCv36	mm8
Celera	9	122,648,694 - 122,763,329 (-)	NCBI		Celera
Cytogenetic Map	9	F4	NCBI
cM Map	9	72.94	NCBI

Ano10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	130,719,177 - 130,838,243 (-)	NCBI		GRCr8
mRatBN7.2	8	121,841,664 - 121,960,739 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	121,841,665 - 121,962,670 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	130,812,941 - 130,931,021 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	130,813,214 - 130,930,990 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	129,980,663 - 130,096,581 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	121,978,317 - 122,095,649 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	121,998,529 - 122,098,310 (-)	NCBI
Celera	8	120,965,429 - 121,079,775 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

ANO10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	43,312,920 - 43,638,518 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	43,317,672 - 43,643,283 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	43,255,858 - 43,581,466 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	44,317,137 - 44,571,627 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	44,317,708 - 44,555,535 (-)	Ensembl	panpan1.1		panPan2

ANO10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	2,678,659 - 2,900,490 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	2,678,615 - 2,902,431 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	2,716,093 - 2,944,138 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	17,606 - 102,144 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	23	2,767,431 - 2,995,700 (+)	NCBI		UMICH_Zoey_3.1
UU_Cfam_GSD_1.0	23	2,866,593 - 3,094,486 (+)	NCBI		UU_Cfam_GSD_1.0

Ano10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	199,374,200 - 199,547,712 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936695	1,726,141 - 1,900,040 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936695	1,726,380 - 1,904,399 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANO10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	26,734,107 - 27,006,539 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	26,734,098 - 27,006,163 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	29,629,839 - 29,834,049 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANO10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	4,807,612 - 5,050,437 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	4,805,218 - 5,050,158 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	162,139,357 - 162,388,553 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ano10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	76,500,179 - 76,638,500 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	76,500,200 - 76,650,802 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005383486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01021456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01021457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01079973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000023363 ⟹ ENSCLAP00000023142

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955420	27,572,561 - 27,682,099 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000023364 ⟹ ENSCLAP00000023143

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955420	27,586,694 - 27,696,269 (+)	Ensembl

RefSeq Acc Id:

XM_005383486 ⟹ XP_005383543

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955420	27,572,561 - 27,682,099 (+)	NCBI

Sequence:

show sequence

GCCCCGCCCCCCTGCGGGAGCGTCCCCTCGCGGCCGGGTCTCGCGGCTCCACGCCGGCTGAAGA
CAGCGGCTCGCGGCGGCGTAAGTTCGTCAAAGATGAAAGTGACCTTATCGGCTTTGGATACTTA
TGAGACTTCTTTCACGCCTTTGGTGGTCATAGAACTTGCTCAGGATGTCAAAGAAGAAACCAAA
GAATGGCTGAAAAGCAGAATTATTGCTAAGAAGAAAGATGGAGGTGCCCAGTTGCTGTTCAGAC
CCCTGTTAAATAAGCAGGAAAAGGAAACACTAGGAAATGAGAACTTGTACCTCGTGGGTGCCTC
CAGGACCCGCCTGCTTCTGGGCGCGGAGGCAGTGGGGCTGGTGAGAGAGTGCATGGATGGCACC
ATGCGCGCCTTCACCTATGGCACCCGGCTCAGCTTCAGAGGCTTCCACGATGACAATGACGATT
TCCTCACCATGGCAGAATGTCAATTCATTGTCAAACATGAGCTGGAAAATCTTAGAGCTAGAGA
TGAGAAGATGATCCCGGGGTACCCTCAAGCGAAGCTGTATCCAGGAAAGTCTCTGTTGAGAAGG
CTGCTCACGTCTGGCATTGTGCTCCAGGTGTTCCCGCTGCACGACAACGAGGCCCTGAAGAAGC
TGGAGGACACCTGGTACACTCGCTTCTCCTTGCACTATCAGCCCGTAGACCATATTCGTGGCTA
CTTTGGGGAAACGATTGCTCTTTACTTCGGGTTTTTGGAGTTTTTCACTTTTGCCTTAATCCCC
ATGGCTGTCATTGGACTGCCATACTACTTGTTCGTGTGGGAGGACTATGACAAGTACGTGATCT
TCGCCTCCTTCAACCTCATCTGGTCCACCGTGATCCTGGAGGTGTGGAAGCGCGGCTGTGCCGA
CATGACCTACCGGTGGGGGACGCTGGTCATGAAGAGACAGTTCGAGGAGCCCCGGCCTGGGTTC
CATGGGGTCCTGGGTGTCAATCCGGTCACCGGCAGGGAGGAGCCCCTCTACCCAAGCTACAAGA
GGCAGCTGCGCATCTACCTGGTCTCCCTGCCGTTCGTGTGCCTCTGCCTGTACTTCTCTCTGTA
CGTCATGATGATCTACTTTGACATGGAAGACTGGGCCTTGCATGTCCATGAGGAAAGTGGGACC
GAGTGGACCAGCGTCCTGCTGTACGTGCCCAGCATCATCTACGCCATTGTGATTGAGATCATGA
ACCGCCTCTATCGCTACGCTGCCGAGTTCCTTACTGCCTGGGAGAATCACAGATTGGAATCTGC
CTACCAGAATCACCTCGTTCTGAAAGTCTTAGTGTTCAACTTCCTGAACTGCTTCGCCTCCCTC
TTCTACATCGCCTTCGTCCTGAAGGACATGAAGCTTCTGGGCCAGAGCTTGGCCACCCTCCTGA
TCACCTCCCAGGTCATTAACCAAATCCTGGAATCTCTTCTTCCTTACTGGCTGCAAAAGAAGCA
CAGTGTGAAGGTCAAGAGGAAGGTGCAGGCTTTAAAGGTGGACGTTGATGCCACATTATATGAA
CAGGTCATCTTGGAAAAAGAAATGGGGACGTATTTGGGCACCTTTGATGACTACTTGGAGCTCT
TCCTGCAGTTTGGTTATGTGAGCCTCTTCTCCTGTGTTTACCCCTTAGCAGCGGCCTTTGCTGT
GCTAAACAACTTCACAGAAGTCAGTTCAGATGCCTTAAAGATGTGCAGGGTCTTCAAACGTCCA
TTCTCGGAGCCTTCAGCCAGCATTGGTGTGTGGCAGTTGGCTTTTGAAACAATGAGTGTCATAT
CTGTGGTCACAAATTGTGCTCTGATTGGAATGTCGCCGCAAGTGAACGCAATCTTTCCAGAGTC
AAAAACGGACCTCGTTCTGATTGTGGTTGCAGTGGAGCACGCACTCCTGGCTCTGAAGTTCATA
CTTGCGTTTGCCATCCCTGACAAACCACGCCACGTGCAGATGAAACTGGCCAGGCTGGAATTTG
AGTCTTTGGAGGCCCTGAAGCAGCAGGTAACAGAAAAGAATGTCCAGTGTTTCTTTTGTAAGTG
ACAGAGACAGTTCCCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005383543	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000023142
	ENSCLAP00000023142.1
	ENSCLAP00000023143.1

RefSeq Acc Id:

XP_005383543 ⟸ XM_005383486

- UniProtKB:

A0A8C2YTZ7 (UniProtKB/TrEMBL), A0A8C2YTY8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKVTLSALDTYETSFTPLVVIELAQDVKEETKEWLKSRIIAKKKDGGAQLLFRPLLNKQEKETL
GNENLYLVGASRTRLLLGAEAVGLVRECMDGTMRAFTYGTRLSFRGFHDDNDDFLTMAECQFIV
KHELENLRARDEKMIPGYPQAKLYPGKSLLRRLLTSGIVLQVFPLHDNEALKKLEDTWYTRFSL
HYQPVDHIRGYFGETIALYFGFLEFFTFALIPMAVIGLPYYLFVWEDYDKYVIFASFNLIWSTV
ILEVWKRGCADMTYRWGTLVMKRQFEEPRPGFHGVLGVNPVTGREEPLYPSYKRQLRIYLVSLP
FVCLCLYFSLYVMMIYFDMEDWALHVHEESGTEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFL
TAWENHRLESAYQNHLVLKVLVFNFLNCFASLFYIAFVLKDMKLLGQSLATLLITSQVINQILE
SLLPYWLQKKHSVKVKRKVQALKVDVDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFS
CVYPLAAAFAVLNNFTEVSSDALKMCRVFKRPFSEPSASIGVWQLAFETMSVISVVTNCALIGM
SPQVNAIFPESKTDLVLIVVAVEHALLALKFILAFAIPDKPRHVQMKLARLEFESLEALKQQVT
EKNVQCFFCK

hide sequence

RefSeq Acc Id:

ENSCLAP00000023143 ⟸ ENSCLAT00000023364

RefSeq Acc Id:

ENSCLAP00000023142 ⟸ ENSCLAT00000023363

Protein Domains

Anoctamin transmembrane

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000015887	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000023363	ENTREZGENE
	ENSCLAT00000023363.1	UniProtKB/TrEMBL
	ENSCLAT00000023364.1	UniProtKB/TrEMBL
InterPro	Anoctamin	UniProtKB/TrEMBL
	Anoctamin_TM	UniProtKB/TrEMBL
NCBI Gene	Ano10	ENTREZGENE
PANTHER	PTHR12308	UniProtKB/TrEMBL
	PTHR12308:SF40	UniProtKB/TrEMBL
Pfam	Anoctamin	UniProtKB/TrEMBL
UniProt	A0A8C2YTY8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2YTZ7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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