Klb (klotho beta) - Rat Genome Database

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Gene: Klb (klotho beta) Chinchilla lanigera
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Symbol: Klb
Name: klotho beta
RGD ID: 8906879
Description: ENCODES a protein that exhibits fibroblast growth factor binding (ortholog); fibroblast growth factor receptor binding (ortholog); INVOLVED IN fibroblast growth factor receptor signaling pathway (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH non-alcoholic fatty liver disease (ortholog); retinitis pigmentosa (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: beta-klotho
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,917,585 - 7,954,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,917,047 - 7,954,390 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Klb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,917,585 - 7,954,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,917,047 - 7,954,390 (-)NCBIChiLan1.0ChiLan1.0
KLB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl439,406,930 - 39,451,533 (+)EnsemblGRCh38hg38GRCh38
GRCh38439,406,930 - 39,451,533 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37439,408,550 - 39,453,153 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,084,868 - 39,126,748 (+)NCBINCBI36hg18NCBI36
Celera439,846,293 - 39,890,979 (+)NCBI
Cytogenetic Map4p14NCBI
HuRef438,733,659 - 38,778,142 (+)NCBIHuRef
CHM1_1439,407,982 - 39,452,605 (+)NCBICHM1_1
Klb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,505,754 - 65,544,300 (+)NCBIGRCm39mm39
GRCm39 Ensembl565,505,657 - 65,541,350 (+)Ensembl
GRCm38565,348,411 - 65,386,957 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,348,314 - 65,384,007 (+)EnsemblGRCm38mm10GRCm38
MGSCv37565,739,650 - 65,775,242 (+)NCBIGRCm37mm9NCBIm37
MGSCv36565,627,546 - 65,663,138 (+)NCBImm8
Celera562,625,529 - 62,660,680 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
Klb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21442,899,050 - 42,950,788 (-)NCBI
Rnor_6.01444,529,523 - 44,614,093 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01444,362,418 - 44,428,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,598,875 - 45,650,432 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11445,601,737 - 45,652,823 (-)NCBI
Celera1442,059,574 - 42,094,328 (-)NCBICelera
Cytogenetic Map14p11NCBI
KLB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1439,588,702 - 39,632,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,588,702 - 39,632,480 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0433,736,350 - 33,780,309 (+)NCBIMhudiblu_PPA_v0panPan3
KLB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,996,725 - 73,033,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,998,816 - 73,033,651 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,543,588 - 75,580,413 (-)NCBI
ROS_Cfam_1.0373,770,160 - 73,807,259 (-)NCBI
UMICH_Zoey_3.1373,036,749 - 73,073,594 (-)NCBI
UNSW_CanFamBas_1.0373,183,012 - 73,219,858 (-)NCBI
UU_Cfam_GSD_1.0373,569,554 - 73,606,370 (-)NCBI
Klb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,238,635 - 39,271,423 (-)NCBI
SpeTri2.0NW_0049364827,026,871 - 7,060,495 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,653,572 - 30,691,349 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,653,434 - 30,696,123 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,268,411 - 32,303,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,860,301 - 10,933,480 (-)NCBI
ChlSab1.1 Ensembl2710,861,760 - 10,903,400 (-)Ensembl
Klb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248704,835,943 - 4,901,965 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002075   ⟹   ENSCLAP00000002030
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554437,917,585 - 7,954,322 (-)Ensembl
RefSeq Acc Id: XM_013518072   ⟹   XP_013373526
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554437,917,047 - 7,954,390 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013373526 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013373526   ⟸   XM_013518072
- Sequence:
RefSeq Acc Id: ENSCLAP00000002030   ⟸   ENSCLAT00000002075


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001476 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000002030 ENTREZGENE
Ensembl Transcript ENSCLAT00000002075 ENTREZGENE
NCBI Gene Klb ENTREZGENE