Syde2 (synapse defective Rho GTPase homolog 2) - Rat Genome Database

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Gene: Syde2 (synapse defective Rho GTPase homolog 2) Chinchilla lanigera
Analyze
Symbol: Syde2
Name: synapse defective Rho GTPase homolog 2
RGD ID: 8902708
Description: INVOLVED IN cell migration (ortholog); ASSOCIATED WITH genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein SYDE2; synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554238,783,116 - 8,838,665 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554238,783,116 - 8,839,927 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Syde2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554238,783,116 - 8,838,665 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554238,783,116 - 8,839,927 (+)NCBIChiLan1.0ChiLan1.0
SYDE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38185,152,491 - 85,201,016 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl185,156,889 - 85,201,724 (-)EnsemblGRCh38hg38GRCh38
GRCh37185,622,572 - 85,666,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36185,395,944 - 85,439,316 (-)NCBINCBI36Build 36hg18NCBI36
Celera183,867,794 - 83,911,153 (-)NCBICelera
Cytogenetic Map1p22.3NCBI
HuRef183,733,947 - 83,777,560 (-)NCBIHuRef
CHM1_1185,738,965 - 85,782,326 (-)NCBICHM1_1
T2T-CHM13v2.0184,997,997 - 85,042,131 (-)NCBIT2T-CHM13v2.0
Syde2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393145,693,160 - 145,727,475 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3145,693,625 - 145,727,475 (+)EnsemblGRCm39 Ensembl
GRCm383145,987,405 - 146,021,720 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3145,987,870 - 146,021,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv373145,650,834 - 145,684,684 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363145,924,785 - 145,959,489 (+)NCBIMGSCv36mm8
MGSCv363146,523,395 - 146,558,245 (+)NCBIMGSCv36mm8
Celera3152,441,267 - 152,475,540 (+)NCBICelera
Cytogenetic Map3H2NCBI
cM Map371.03NCBI
Syde2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82237,557,395 - 237,591,290 (+)NCBIGRCr8
mRatBN7.22234,897,975 - 234,930,994 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2234,897,717 - 234,930,994 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2242,690,164 - 242,723,132 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02240,580,564 - 240,613,520 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02235,447,782 - 235,480,755 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02251,861,900 - 251,895,524 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2251,863,069 - 251,894,037 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02270,385,411 - 270,419,064 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42244,166,412 - 244,199,033 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2226,880,380 - 226,913,328 (+)NCBICelera
Cytogenetic Map2q44NCBI
SYDE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21141,731,421 - 141,781,181 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11140,886,701 - 140,936,510 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01117,713,925 - 117,759,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1186,571,404 - 86,615,051 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl186,571,431 - 86,615,051 (-)Ensemblpanpan1.1panPan2
SYDE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1662,768,892 - 62,822,550 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl662,775,056 - 62,820,677 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha665,422,892 - 65,471,269 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0663,314,310 - 63,362,687 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl663,314,148 - 63,360,988 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1662,841,461 - 62,889,829 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0662,811,662 - 62,860,036 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0663,319,495 - 63,367,884 (+)NCBIUU_Cfam_GSD_1.0
Syde2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505895,765,663 - 95,803,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936608503,043 - 540,359 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936608502,909 - 540,370 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYDE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4130,702,424 - 130,749,734 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14130,702,340 - 130,749,742 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24143,278,477 - 143,325,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYDE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12048,146,793 - 48,190,946 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2048,149,023 - 48,190,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603369,618,409 - 69,660,914 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syde2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474212,299,316 - 12,344,180 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474212,299,250 - 12,349,945 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005795   ⟹   ENSCLAP00000005694
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554238,783,116 - 8,838,665 (+)Ensembl
RefSeq Acc Id: XM_013514551   ⟹   XP_013370005
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554238,783,116 - 8,839,927 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013370005 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005694
  ENSCLAP00000005694.1
Reference Protein Sequences
RefSeq Acc Id: XP_013370005   ⟸   XM_013514551
- UniProtKB: A0A8C2UYT6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005694   ⟸   ENSCLAT00000005795
Protein Domains
C2   Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004038 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005795 ENTREZGENE
  ENSCLAT00000005795.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene Syde2 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 100F UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN SYDE2 UniProtKB/TrEMBL
Pfam RhoGAP UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2UYT6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Syde2  synapse defective Rho GTPase homolog 2    synapse defective 1, Rho GTPase, homolog 2 (C. elegans)  Symbol and/or name change 5135510 APPROVED