Sardh (sarcosine dehydrogenase) - Rat Genome Database

Name: Sardh
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Sardh (sarcosine dehydrogenase) Chinchilla lanigera

Analyze

Symbol:

Sardh

Name:

sarcosine dehydrogenase

RGD ID:

8900997

Description:

ENCODES a protein that exhibits flavin adenine dinucleotide binding (ortholog); folic acid binding (ortholog); sarcosine dehydrogenase activity (ortholog); INVOLVED IN tetrahydrofolate interconversion (ortholog); PARTICIPATES IN choline metabolic pathway; dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sarcosine dehydrogenase, mitochondrial

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SARDH (sarcosine dehydrogenase)	NCBI	Ortholog
Mus musculus (house mouse):	Sardh (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sardh (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SARDH (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SARDH (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sardh (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SARDH (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SARDH (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sardh (sarcosine dehydrogenase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	2,933,918 - 2,976,931 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	2,933,918 - 2,975,645 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 14 (ISO)

Ehlers-Danlos syndrome classic type 1 (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Hypoxia (ISO)

Kleefstra syndrome 1 (ISO)

Leigh disease (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Rafiq syndrome (ISO)

sarcosinemia (ISO)

tuberous sclerosis 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

tetrahydrofolate interconversion (ISO)

Cellular Component

mitochondrial matrix (ISO)

mitochondrion (ISO)

Molecular Function

flavin adenine dinucleotide binding (ISO)

folic acid binding (ISO)

sarcosine dehydrogenase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

choline metabolic pathway (ISO)

dihydropyrimidine dehydrogenase deficiency pathway (ISO)

dimethylglycine dehydrogenase deficiency pathway (ISO)

folate cycle metabolic pathway (ISO)

nonketotic hyperglycinemia pathway (ISO)

sarcosinemia pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Sardh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	2,933,918 - 2,976,931 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	2,933,918 - 2,975,645 (-)	NCBI	ChiLan1.0	ChiLan1.0

SARDH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	133,659,418 - 133,739,955 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	133,663,560 - 133,739,955 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	136,528,682 - 136,605,077 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	135,518,503 - 135,594,863 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	133,558,235 - 133,634,596	NCBI
Celera	9	107,075,562 - 107,151,924 (-)	NCBI		Celera
Cytogenetic Map	9	q34.2	NCBI
HuRef	9	106,029,059 - 106,104,804 (-)	NCBI		HuRef
CHM1_1	9	136,678,641 - 136,754,578 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	145,875,436 - 145,955,389 (-)	NCBI		T2T-CHM13v2.0

Sardh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	27,078,405 - 27,138,344 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	27,078,405 - 27,138,349 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	27,188,393 - 27,248,332 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	27,188,393 - 27,248,337 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	27,044,902 - 27,102,332 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	27,011,391 - 27,068,821 (-)	NCBI		MGSCv36	mm8
Celera	2	26,892,296 - 26,949,897 (-)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.31	NCBI

Sardh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	30,908,621 - 30,973,409 (-)	NCBI		GRCr8
mRatBN7.2	3	10,510,553 - 10,575,342 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	10,510,553 - 10,573,874 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	13,577,541 - 13,639,718 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	22,162,940 - 22,225,121 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,418,235 - 20,480,397 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	5,737,203 - 5,802,153 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	5,737,200 - 5,802,129 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	11,100,670 - 11,164,367 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	6,076,166 - 6,142,565 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	6,076,465 - 6,142,865 (-)	NCBI
Celera	3	5,308,395 - 5,369,033 (-)	NCBI		Celera
Cytogenetic Map	3	p12	NCBI

SARDH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	5,613,842 - 5,696,750 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	5,616,176 - 5,696,436 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	104,786,774 - 104,864,480 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	133,398,806 - 133,473,642 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	133,398,806 - 133,473,642 (-)	Ensembl	panpan1.1		panPan2

SARDH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	50,030,397 - 50,093,556 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	50,030,707 - 50,091,553 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	49,310,923 - 49,374,527 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	50,904,459 - 50,967,629 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	50,904,464 - 50,967,596 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	49,665,765 - 49,728,991 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	50,007,753 - 50,071,562 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	50,086,168 - 50,149,420 (-)	NCBI		UU_Cfam_GSD_1.0

Sardh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	200,077,144 - 200,131,802 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936669	3,243,762 - 3,297,905 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936669	3,244,302 - 3,297,906 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SARDH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	273,230,375 - 273,294,621 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	273,230,357 - 273,295,170 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	307,204,192 - 307,268,081 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SARDH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	4,397,312 - 4,469,890 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	4,397,539 - 4,469,562 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666058	519,221 - 596,979 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sardh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	2,032,326 - 2,066,584 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	2,030,835 - 2,070,517 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005408456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013506717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01066892	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01214329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000006791 ⟹ ENSCLAP00000006681

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955513	2,933,918 - 2,976,931 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000006792 ⟹ ENSCLAP00000006682

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955513	2,934,164 - 2,975,827 (-)	Ensembl

RefSeq Acc Id:

XM_005408456 ⟹ XP_005408513

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955513	2,933,918 - 2,975,644 (-)	NCBI

Sequence:

show sequence

GGCGGGGACACTGGGCAGCTGCGAGGGGGAGGGTGGGCCTGTTCCGGCTAGACCACGGCTTGGG
AGGAAGGAAGGCAGTGACCGTGCCTCCACTGTCCAGACACGCAGGAGGAGCTCCTGCCCGAAGC
CCAGAGCCCCATGGCCTCGCTGAGCCGAGCCCTGCGCGTGGCTGCCGCCTACCCTCGTTGGAGA
CCAGCCCAGCACCTGAGGCTGCAGACTCTGGCCGGTGTTACGGGCCCCACGGCTGAGAAGAATG
TGCCCTACCACCGCACCCTGAAGGAGGAGGCCCAGGGCCCTTCGGCGGCAGCCCAAGGACCCAG
CCAGCCCCTGCCCAGCACAGCCAGTGTGGTGATCATTGGCGGGGGCAGCTTGGGCTGCCAGACC
CTGTACCACCTGGCCAAGCTGGGTGTGACTGGGGCCGTGCTCCTGGAGCGTGAGCGACTGACGT
CGGGGACCACCTGGCACACAGCAGGCCTGCTGTGGCAGCTGCGGCCCAGCGACGTGGAGGTGGA
GCTGCTGGCCCACACCAGGCGTGTGGTGAGCCAAGAGCTGGAGGCGGAGACCGGGCTGCACACG
GGCTGGATCCAGAACGGGGGCCTCTTCATCGCGTCCAGCCGGCAGCGCCTGGATGAGTACAAGA
GGCTCATGTCGCTGGGCAAGGCCTATGGTGTGGAGTCCCACGTGCTGAGTCCTGCGGAGACCAA
GGCTCTGTACCCGCTGATGAACGTGGACGACCTCTACGGGACCTTGTATGTGCCACAGGACGGC
ACCATGGACCCCGCCGGCACCTGCACCACCCTCGCCAGGGCCGCTGTGGCCCGAGGAGCCCAGG
TCATCGAGAAGTGCCCCGTGACGGGGATCCGCATGCGGACTGATGATTTTGGGGTGCGGCGTGT
TGCGGCTGTGGAGACGGAGCACGGCTCCATCCAGACGCCCTGCGTGGTCAACTGTGCAGGCGTG
TGGGCAGGCGCTGTGGGCCGGATGGCTGGAGTCAAGGTGCCCCTGGTGGCCATGCACCACGCCT
ACGTCGTCACGGAGCGCATCGAGGGGATCCAGAATATGCCCAATGTCCGTGACCACGATGCCTC
TGTCTACCTGCGCCTGCAAGGGGACGCCCTGTCTGTGGGTGGCTACGAGGCCAACCCCATCTTC
TGGGAGGAGGTGTCAGACAAGTTCGCCTTCGGCCTGTTTGACCTGGACTGGGACGTGTTTACCC
AGCACATCGAGGGTGCCATCAACCGTGTCCCTGCGCTGGAGACCACGGGGATCAAGTCTACGGT
CTGTGGCCCGGAGTCCTTCACGCCCGACCACAAGCCCCTGATGGGGGAGGCGCCCGAGCTGCGG
GGCTTCTTCCTGGGCTGCGGCTTCAACAGCGCTGGGATGATGCTGGGCGGCGGCTGTGGACAGG
AGCTGGCCCGCTGGGTCGTCTACGGGCGCCCGGAGAAGGACATGTACAGCTACGACATCAGACG
CTTCCACCACTCCCTGACCGAGCACCAGCGCTGGATCCGCGAGCGCAGTCACGAGTCCTACGCC
AAGAACTACTCGGTCGTCTTCCCCCATGACGAGCCGCTGGCGGGGCGCAACATGCGGAGGGGCC
CCCTGCATGAGGAACTCCTGGGACGAGGCTGCGTGTTCCAGGAGCGACATGGCTGGGAGCGGCC
TGGATGGTTCAACCCCCAGGGGCCAGCTCCGGTCCTCGACTATGACTACTATGGTGCCTACGGG
AAGCGGCCTCACCAGGACTACGCCTACGGCCGGCTGCTGAGTGACGAGTACACCTTCGACTTCC
CGCCCCATCACCACCTGATCCAGAAGGAGTGCCTGGCCTGCCGAGGGGCGGCTGCTGTGTTCGA
CATGTCCTACTTCGGGAAGTTCTACCTGCTGGGGCCCGACGCTGCGAAAGCTGCGGACTGGCTC
TTCTCAGCCAACGTCAGGCGACCCCCAGGCTCCACGGTGTACACCTGCATGCTGAACCACAGGG
GCGGCACGGAGAGTGACCTGACAGTCAGCTGCCTGGCCCCCGGGACCCAGGCCTGCCTGGTGGC
CCCTGCCTTCGAAGGGAATGGCTACTACCTGGCTGTGGGCGGGGCCACCGCCCAGCATAACTGG
TGCCACATCACCACCGTGCTGCAGGACCAGAGGTTCCGGTGCCGGCTCGTTGACTGCTCTGAGG
ACCTGGGCCTGATCAGCATCCAGGGCCCAGCCAGCCGGGCCATCCTGCAGGAGGTGCTGGACGC
AGACCTGAGTGATGCCGCCTTCCCCTTCTCCACCCACCAGCTGGTGCAAGCTGCTGGGCACCTG
GTCCGGGCTGTGAGGCTGTCCTTCGTGGGGGAGCTGGGCTGGGAGCTGCACGTTCCCCGGGCCT
CCTGCGTGCCTGTGTACCGGGCCGTGATGACCGCAGGAGCCAAGCATGGCCTTGTCAACGCCGG
GTACCGTGCCATCGACTCCCTGAGCATTGAGAAAGGCTACCGGCACTGGCATGCAGACCTGCGG
CCTGATGACAGCCCCCTGGAAGCCGGCCTGGCCTTCACCTGCAAGCTTAAGTCGGCCGTGCCCT
TCCTGGGCCGTGAGGCCCTGGAGCAGCAGCGGGCCGCGGGCCTCCGCCGGCGTCTCGTGTGCTT
CACAGTGGAAGAGAAGGTACCCATGTTCGGCCTGGAGGCCATCTGGAGGGATGGCCAGGTGGTG
GGCCACGTGCGGCGGGCCGACTTCGGGTTCGCCGTGGATAAGACCATCGCCTATGGCTACATCT
GTGATCCCAGCGGCGGGCCGGTCTCGCTGGACTTCGTGAAGAGTGGGGACTATGTCCTGGAGAG
GATGGGGGTCCCGTACACTGCCCAGGTCCACCTGAAATCCCCCTTCGACCCCGACAACAAGAGG
GTGAAGGGGATCTACTGAGGGGCCCGAAGCAGGAGCACACCTGTCCCCCCCACTGGGCCCTCCC
TGTCCTCAGCCTGGGCCTGGCCTGCTATACCACAAGCTAGGAATGGACAGAGATCACCATGGCC
TGTCCAGTGCCTACTGACCGGGGTCTGTGCCTAGCTCACCCCAGGCCTCCCTGTATGGTTTTGG
GCACAGGGGCCTCACTTTGTAACCCTGTGAGCTTCCCAGGCTGTGAAGTAAAACTTGGTAAGTG
GCGTAGAA

hide sequence

RefSeq Acc Id:

XM_013506717 ⟹ XP_013362171

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955513	2,933,918 - 2,975,645 (-)	NCBI

Sequence:

show sequence

GGGCGGGGACACTGGGCAGCTGCGAGGGGGAGGGTGGGCCTGTTCCGGCTAGACCACGGCTTGG
GAGGAAGGAAGGCAGTGACCGTGCCTCCACTGTCCAGACACGCAGGAGGAGCTCCTGCCCGAAG
CCCAGAGCCCCATGGCCTCGCTGAGCCGAGCCCTGCGCGTGGCTGCCGCCTACCCTCGTTGGAG
ACCAGCCCAGCACCTGAGGCTGCAGACTCTGGCCGGTGTTACGGGCCCCACGGCTGAGAAGAAT
GTGCCCTACCACCGCACCCTGAAGGAGGAGGCCCAGGGCCCTTCGGCGGCAGCCCAAGGACCCA
GCCAGCCCCTGCCCAGCACAGCCAGTGTGGTGATCATTGGCGGGGGCAGCTTGGGCTGCCAGAC
CCTGTACCACCTGGCCAAGCTGGGTGTGACTGGGGCCGTGCTCCTGGAGCGTGAGCGACTGACG
TCGGGGACCACCTGGCACACAGCAGGCCTGCTGTGGCAGCTGCGGCCCAGCGACGTGGAGGTGG
AGCTGCTGGCCCACACCAGGCGTGTGGTGAGCCAAGAGCTGGAGGCGGAGACCGGGCTGCACAC
GGGCTGGATCCAGAACGGGGGCCTCTTCATCGCGTCCAGCCGGCAGCGCCTGGATGAGTACAAG
AGGCTCATGTCGCTGGGCAAGGCCTATGGTGTGGAGTCCCACGTGCTGAGTCCTGCGGAGACCA
AGGCTCTGTACCCGCTGATGAACGTGGACGACCTCTACGGGACCTTGTATGTGCCACAGGACGG
CACCATGGACCCCGCCGGCACCTGCACCACCCTCGCCAGGGCCGCTGTGGCCCGAGGAGCCCAG
GTCATCGAGAAGTGCCCCGTGACGGGGATCCGCATGCGGACTGATGATTTTGGGGTGCGGCGTG
TTGCGGCTGTGGAGACGGAGCACGGCTCCATCCAGACGCCCTGCGTGGTCAACTGTGCAGGCGT
GTGGGCAGGCGCTGTGGGCCGGATGGCTGGAGTCAAGGTGCCCCTGGTGGCCATGCACCACGCC
TACGTCGTCACGGAGCGCATCGAGGGGATCCAGGTGTCAGACAAGTTCGCCTTCGGCCTGTTTG
ACCTGGACTGGGACGTGTTTACCCAGCACATCGAGGGTGCCATCAACCGTGTCCCTGCGCTGGA
GACCACGGGGATCAAGTCTACGGTCTGTGGCCCGGAGTCCTTCACGCCCGACCACAAGCCCCTG
ATGGGGGAGGCGCCCGAGCTGCGGGGCTTCTTCCTGGGCTGCGGCTTCAACAGCGCTGGGATGA
TGCTGGGCGGCGGCTGTGGACAGGAGCTGGCCCGCTGGGTCGTCTACGGGCGCCCGGAGAAGGA
CATGTACAGCTACGACATCAGACGCTTCCACCACTCCCTGACCGAGCACCAGCGCTGGATCCGC
GAGCGCAGTCACGAGTCCTACGCCAAGAACTACTCGGTCGTCTTCCCCCATGACGAGCCGCTGG
CGGGGCGCAACATGCGGAGGGGCCCCCTGCATGAGGAACTCCTGGGACGAGGCTGCGTGTTCCA
GGAGCGACATGGCTGGGAGCGGCCTGGATGGTTCAACCCCCAGGGGCCAGCTCCGGTCCTCGAC
TATGACTACTATGGTGCCTACGGGAAGCGGCCTCACCAGGACTACGCCTACGGCCGGCTGCTGA
GTGACGAGTACACCTTCGACTTCCCGCCCCATCACCACCTGATCCAGAAGGAGTGCCTGGCCTG
CCGAGGGGCGGCTGCTGTGTTCGACATGTCCTACTTCGGGAAGTTCTACCTGCTGGGGCCCGAC
GCTGCGAAAGCTGCGGACTGGCTCTTCTCAGCCAACGTCAGGCGACCCCCAGGCTCCACGGTGT
ACACCTGCATGCTGAACCACAGGGGCGGCACGGAGAGTGACCTGACAGTCAGCTGCCTGGCCCC
CGGGACCCAGGCCTGCCTGGTGGCCCCTGCCTTCGAAGGGAATGGCTACTACCTGGCTGTGGGC
GGGGCCACCGCCCAGCATAACTGGTGCCACATCACCACCGTGCTGCAGGACCAGAGGTTCCGGT
GCCGGCTCGTTGACTGCTCTGAGGACCTGGGCCTGATCAGCATCCAGGGCCCAGCCAGCCGGGC
CATCCTGCAGGAGGTGCTGGACGCAGACCTGAGTGATGCCGCCTTCCCCTTCTCCACCCACCAG
CTGGTGCAAGCTGCTGGGCACCTGGTCCGGGCTGTGAGGCTGTCCTTCGTGGGGGAGCTGGGCT
GGGAGCTGCACGTTCCCCGGGCCTCCTGCGTGCCTGTGTACCGGGCCGTGATGACCGCAGGAGC
CAAGCATGGCCTTGTCAACGCCGGGTACCGTGCCATCGACTCCCTGAGCATTGAGAAAGGCTAC
CGGCACTGGCATGCAGACCTGCGGCCTGATGACAGCCCCCTGGAAGCCGGCCTGGCCTTCACCT
GCAAGCTTAAGTCGGCCGTGCCCTTCCTGGGCCGTGAGGCCCTGGAGCAGCAGCGGGCCGCGGG
CCTCCGCCGGCGTCTCGTGTGCTTCACAGTGGAAGAGAAGGTACCCATGTTCGGCCTGGAGGCC
ATCTGGAGGGATGGCCAGGTGGTGGGCCACGTGCGGCGGGCCGACTTCGGGTTCGCCGTGGATA
AGACCATCGCCTATGGCTACATCTGTGATCCCAGCGGCGGGCCGGTCTCGCTGGACTTCGTGAA
GAGTGGGGACTATGTCCTGGAGAGGATGGGGGTCCCGTACACTGCCCAGGTCCACCTGAAATCC
CCCTTCGACCCCGACAACAAGAGGGTGAAGGGGATCTACTGAGGGGCCCGAAGCAGGAGCACAC
CTGTCCCCCCCACTGGGCCCTCCCTGTCCTCAGCCTGGGCCTGGCCTGCTATACCACAAGCTAG
GAATGGACAGAGATCACCATGGCCTGTCCAGTGCCTACTGACCGGGGTCTGTGCCTAGCTCACC
CCAGGCCTCCCTGTATGGTTTTGGGCACAGGGGCCTCACTTTGTAACCCTGTGAGCTTCCCAGG
CTGTGAAGTAAAACTTGGTAAGTGGCGTAGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005408513	(Get FASTA)	NCBI Sequence Viewer
	XP_013362171	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000006681.1
	ENSCLAP00000006682
	ENSCLAP00000006682.1

RefSeq Acc Id:	XP_005408513 ⟸ XM_005408456
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2UX06 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASLSRALRVAAAYPRWRPAQHLRLQTLAGVTGPTAEKNVPYHRTLKEEAQGPSAAAQGPSQPL PSTASVVIIGGGSLGCQTLYHLAKLGVTGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLA HTRRVVSQELEAETGLHTGWIQNGGLFIASSRQRLDEYKRLMSLGKAYGVESHVLSPAETKALY PLMNVDDLYGTLYVPQDGTMDPAGTCTTLARAAVARGAQVIEKCPVTGIRMRTDDFGVRRVAAV ETEHGSIQTPCVVNCAGVWAGAVGRMAGVKVPLVAMHHAYVVTERIEGIQNMPNVRDHDASVYL RLQGDALSVGGYEANPIFWEEVSDKFAFGLFDLDWDVFTQHIEGAINRVPALETTGIKSTVCGP ESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGGGCGQELARWVVYGRPEKDMYSYDIRRFHH SLTEHQRWIRERSHESYAKNYSVVFPHDEPLAGRNMRRGPLHEELLGRGCVFQERHGWERPGWF NPQGPAPVLDYDYYGAYGKRPHQDYAYGRLLSDEYTFDFPPHHHLIQKECLACRGAAAVFDMSY FGKFYLLGPDAAKAADWLFSANVRRPPGSTVYTCMLNHRGGTESDLTVSCLAPGTQACLVAPAF EGNGYYLAVGGATAQHNWCHITTVLQDQRFRCRLVDCSEDLGLISIQGPASRAILQEVLDADLS DAAFPFSTHQLVQAAGHLVRAVRLSFVGELGWELHVPRASCVPVYRAVMTAGAKHGLVNAGYRA IDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLKSAVPFLGREALEQQRAAGLRRRLVCFTVE EKVPMFGLEAIWRDGQVVGHVRRADFGFAVDKTIAYGYICDPSGGPVSLDFVKSGDYVLERMGV PYTAQVHLKSPFDPDNKRVKGIY hide sequence

RefSeq Acc Id:

XP_013362171 ⟸ XM_013506717

- Peptide Label:

isoform X2

- Sequence:

show sequence

MASLSRALRVAAAYPRWRPAQHLRLQTLAGVTGPTAEKNVPYHRTLKEEAQGPSAAAQGPSQPL
PSTASVVIIGGGSLGCQTLYHLAKLGVTGAVLLERERLTSGTTWHTAGLLWQLRPSDVEVELLA
HTRRVVSQELEAETGLHTGWIQNGGLFIASSRQRLDEYKRLMSLGKAYGVESHVLSPAETKALY
PLMNVDDLYGTLYVPQDGTMDPAGTCTTLARAAVARGAQVIEKCPVTGIRMRTDDFGVRRVAAV
ETEHGSIQTPCVVNCAGVWAGAVGRMAGVKVPLVAMHHAYVVTERIEGIQVSDKFAFGLFDLDW
DVFTQHIEGAINRVPALETTGIKSTVCGPESFTPDHKPLMGEAPELRGFFLGCGFNSAGMMLGG
GCGQELARWVVYGRPEKDMYSYDIRRFHHSLTEHQRWIRERSHESYAKNYSVVFPHDEPLAGRN
MRRGPLHEELLGRGCVFQERHGWERPGWFNPQGPAPVLDYDYYGAYGKRPHQDYAYGRLLSDEY
TFDFPPHHHLIQKECLACRGAAAVFDMSYFGKFYLLGPDAAKAADWLFSANVRRPPGSTVYTCM
LNHRGGTESDLTVSCLAPGTQACLVAPAFEGNGYYLAVGGATAQHNWCHITTVLQDQRFRCRLV
DCSEDLGLISIQGPASRAILQEVLDADLSDAAFPFSTHQLVQAAGHLVRAVRLSFVGELGWELH
VPRASCVPVYRAVMTAGAKHGLVNAGYRAIDSLSIEKGYRHWHADLRPDDSPLEAGLAFTCKLK
SAVPFLGREALEQQRAAGLRRRLVCFTVEEKVPMFGLEAIWRDGQVVGHVRRADFGFAVDKTIA
YGYICDPSGGPVSLDFVKSGDYVLERMGVPYTAQVHLKSPFDPDNKRVKGIY

hide sequence

RefSeq Acc Id:

ENSCLAP00000006682 ⟸ ENSCLAT00000006792

RefSeq Acc Id:

ENSCLAP00000006681 ⟸ ENSCLAT00000006791

Protein Domains

Aminomethyltransferase folate-binding FAD dependent oxidoreductase FAD dependent oxidoreductase central Glycine cleavage T-protein C-terminal barrel

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000004708	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000006791.1	UniProtKB/TrEMBL
	ENSCLAT00000006792	ENTREZGENE
	ENSCLAT00000006792.1	UniProtKB/TrEMBL
Gene3D-CATH	3.50.50.60	UniProtKB/TrEMBL
	Aminomethyltransferase beta-barrel domains	UniProtKB/TrEMBL
	Aminomethyltransferase beta-barrel domains	UniProtKB/TrEMBL
	D-Amino Acid Oxidase, subunit A, domain 2	UniProtKB/TrEMBL
InterPro	FAD-dep_OxRdtase	UniProtKB/TrEMBL
	FAD/NAD-bd_sf	UniProtKB/TrEMBL
	FAO_M	UniProtKB/TrEMBL
	GCV_T_C	UniProtKB/TrEMBL
	GCV_T_N	UniProtKB/TrEMBL
	GcvT/YgfZ_C	UniProtKB/TrEMBL
	TrmE/GcvT_dom1	UniProtKB/TrEMBL
NCBI Gene	Sardh	ENTREZGENE
PANTHER	SARCOSINE DEHYDROGENASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	SARCOSINE DEHYDROGENASE-RELATED	UniProtKB/TrEMBL
Pfam	DAO	UniProtKB/TrEMBL
	FAO_M	UniProtKB/TrEMBL
	GCV_T	UniProtKB/TrEMBL
	GCV_T_C	UniProtKB/TrEMBL
Superfamily-SCOP	FAD-linked reductases, C-terminal domain	UniProtKB/TrEMBL
	Folate-binding domain	UniProtKB/TrEMBL
	SSF101790	UniProtKB/TrEMBL
	SSF51905	UniProtKB/TrEMBL
UniProt	A0A8C2UX06	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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