Mrtfa (myocardin related transcription factor A) - Rat Genome Database

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Gene: Mrtfa (myocardin related transcription factor A) Chinchilla lanigera
Analyze
Symbol: Mrtfa
Name: myocardin related transcription factor A
RGD ID: 8891144
Description: ENCODES a protein that exhibits actin binding (ortholog); actin monomer binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); forebrain development (ortholog); negative regulation of apoptotic signaling pathway (ortholog); ASSOCIATED WITH acute megakaryocytic leukemia (ortholog); adenylosuccinase lyase deficiency (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: megakaryoblastic leukemia (translocation) 1; MKL/myocardin-like protein 1; Mkl1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,139,843 - 26,222,580 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,139,060 - 26,311,272 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mrtfa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,139,843 - 26,222,580 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,139,060 - 26,311,272 (-)NCBIChiLan1.0ChiLan1.0
MRTFA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,410,289 - 40,636,719 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,410,281 - 40,636,719 (-)EnsemblGRCh38hg38GRCh38
GRCh372240,806,293 - 41,032,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,136,238 - 39,362,636 (-)NCBINCBI36Build 36hg18NCBI36
Build 342239,130,791 - 39,357,190NCBI
Celera2224,608,353 - 24,836,358 (-)NCBICelera
Cytogenetic Map22q13.1-q13.2NCBI
HuRef2223,769,395 - 23,994,500 (-)NCBIHuRef
CHM1_12240,765,195 - 40,992,703 (-)NCBICHM1_1
T2T-CHM13v2.02240,880,672 - 41,108,683 (-)NCBIT2T-CHM13v2.0
Mrtfa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,896,482 - 81,074,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,896,482 - 81,074,958 (-)EnsemblGRCm39 Ensembl
GRCm381581,012,281 - 81,190,736 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,012,281 - 81,190,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv371580,842,711 - 81,021,187 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,840,540 - 80,932,073 (-)NCBIMGSCv36mm8
Celera1583,132,403 - 83,308,218 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.98NCBI
Mrtfa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,424,481 - 114,594,594 (-)NCBIGRCr8
mRatBN7.27112,544,305 - 112,714,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,544,312 - 112,714,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,306,865 - 114,477,102 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,530,410 - 116,700,653 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,499,783 - 116,670,016 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,233,196 - 122,403,661 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,234,012 - 122,403,667 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,217,533 - 122,387,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,306,220 - 119,415,012 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17119,340,456 - 119,511,326 (-)NCBI
Celera7108,866,997 - 109,036,998 (-)NCBICelera
Cytogenetic Map7q34NCBI
MRTFA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,247,445 - 50,469,280 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,950,372 - 53,172,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,314,829 - 21,536,673 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,411,890 - 39,581,958 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,413,002 - 39,467,402 (-)Ensemblpanpan1.1panPan2
MRTFA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,561,161 - 24,759,586 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,561,161 - 24,759,081 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,496,201 - 24,694,602 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,311,403 - 25,509,948 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,311,348 - 25,509,944 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,024,155 - 25,222,271 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,346,404 - 25,544,515 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,520,463 - 25,718,833 (+)NCBIUU_Cfam_GSD_1.0
Mrtfa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,223,715 - 8,374,424 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,282,674 - 1,383,696 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,234,025 - 1,384,838 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRTFA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,959,312 - 7,972,574 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,751,350 - 7,975,927 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,981,649 - 5,208,382 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRTFA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,980,071 - 23,197,199 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,981,216 - 23,034,179 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045102,390,890 - 102,610,530 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrtfa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,878,876 - 8,050,274 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,836,545 - 8,050,176 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000024747   ⟹   ENSCLAP00000024512
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541326,139,843 - 26,222,580 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000024748   ⟹   ENSCLAP00000024513
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541326,139,843 - 26,153,933 (-)Ensembl
RefSeq Acc Id: XM_013511484   ⟹   XP_013366938
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541326,139,060 - 26,311,272 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013366938 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000024512.1
  ENSCLAP00000024513.1
Reference Protein Sequences
RefSeq Acc Id: XP_013366938   ⟸   XM_013511484
- UniProtKB: A0A8C2YUL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000024512   ⟸   ENSCLAT00000024747
RefSeq Acc Id: ENSCLAP00000024513   ⟸   ENSCLAT00000024748
Protein Domains
SAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016828 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024747.1 UniProtKB/TrEMBL
  ENSCLAT00000024748.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/TrEMBL
  6.10.140.2040 UniProtKB/TrEMBL
  6.10.150.10 UniProtKB/TrEMBL
InterPro Myocardin-like UniProtKB/TrEMBL
  RPEL_repeat UniProtKB/TrEMBL
  SAP_dom UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/TrEMBL
NCBI Gene Mkl1 ENTREZGENE
PANTHER PTHR22793 UniProtKB/TrEMBL
  PTHR22793:SF6 UniProtKB/TrEMBL
Pfam RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
PROSITE RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
SMART RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
Superfamily-SCOP SSF68906 UniProtKB/TrEMBL
UniProt A0A8C2W367_CHILA UniProtKB/TrEMBL
  A0A8C2YUL7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-19 Mrtfa  myocardin related transcription factor A  Mkl1  megakaryoblastic leukemia (translocation) 1  Symbol and/or name change 5135510 APPROVED