Prss33 (serine protease 33) - Rat Genome Database

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Gene: Prss33 (serine protease 33) Chinchilla lanigera
Analyze
Symbol: Prss33
Name: serine protease 33
RGD ID: 8889519
Description: ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN protein kinase C signaling (ortholog); proteolysis (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protease, serine 33; protease, serine, 33
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,521,485 - 14,524,632 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,521,485 - 14,524,632 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Prss33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,521,485 - 14,524,632 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,521,485 - 14,524,632 (-)NCBIChiLan1.0ChiLan1.0
PRSS33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,783,953 - 2,787,915 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,783,953 - 2,787,948 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,833,954 - 2,837,916 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,773,955 - 2,776,709 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,773,954 - 2,776,607NCBI
Celera163,033,522 - 3,036,276 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,801,109 - 2,803,863 (-)NCBIHuRef
CHM1_1162,833,986 - 2,836,740 (-)NCBICHM1_1
T2T-CHM13v2.0162,804,168 - 2,808,494 (-)NCBIT2T-CHM13v2.0
Prss33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,052,312 - 24,055,667 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,052,321 - 24,055,030 (-)EnsemblGRCm39 Ensembl
GRCm381723,833,338 - 23,836,693 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,833,347 - 23,836,056 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,970,327 - 23,972,734 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,560,982 - 23,563,687 (-)NCBIMGSCv36mm8
Celera1724,327,764 - 24,330,235 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.08NCBI
Prss33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,363,528 - 13,365,868 (-)NCBIGRCr8
mRatBN7.21012,858,941 - 12,861,281 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,858,941 - 12,861,281 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,603,477 - 17,605,817 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,092,267 - 17,094,607 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,591,706 - 12,594,046 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,173,509 - 13,176,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,173,529 - 13,175,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,993,494 - 12,996,252 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,095,422 - 13,097,762 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1012,553,805 - 12,556,145 (-)NCBICelera
Cytogenetic Map10q12NCBI
PRSS33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,318,746 - 38,322,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,318,729 - 38,321,841 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,558,641 - 39,562,245 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,629,021 - 38,632,623 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,629,472 - 38,631,257 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,314,663 - 38,318,255 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,287,126 - 38,290,715 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,763,270 - 38,766,874 (-)NCBIUU_Cfam_GSD_1.0
Prss33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,400,660 - 105,404,303 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,305,757 - 1,307,621 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,305,167 - 1,307,695 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRSS33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,302,369 - 39,307,433 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,301,919 - 39,304,996 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,639,901 - 40,643,949 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Prss33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824568,654 - 575,272 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824568,647 - 571,453 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000020335   ⟹   ENSCLAP00000020140
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544214,521,485 - 14,524,632 (-)Ensembl
RefSeq Acc Id: XM_005391403   ⟹   XP_005391460
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544214,521,485 - 14,524,632 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391460 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020140
  ENSCLAP00000020140.1
Reference Protein Sequences
RefSeq Acc Id: XP_005391460   ⟸   XM_005391403
- UniProtKB: A0A8C2VT51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000020140   ⟸   ENSCLAT00000020335
Protein Domains
Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013800 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020335 ENTREZGENE
  ENSCLAT00000020335.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene Prss33 ENTREZGENE
PANTHER SERINE PROTEASE 33 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEASE SERINE UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt A0A8C2VT51 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 Prss33  serine protease 33    protease, serine 33  Symbol and/or name change 5135510 APPROVED
2016-08-16 Prss33  protease, serine 33    protease, serine, 33  Symbol and/or name change 5135510 APPROVED