Eprs1 (glutamyl-prolyl-tRNA synthetase 1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Eprs1 (glutamyl-prolyl-tRNA synthetase 1) Chinchilla lanigera
Analyze
Symbol: Eprs1
Name: glutamyl-prolyl-tRNA synthetase 1
RGD ID: 8889380
Description: ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); proline-tRNA ligase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); cellular response to interferon-gamma (ortholog); negative regulation of translation (ortholog); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; ASSOCIATED WITH Hypomyelinating Leukodystrophy 15 (ortholog); Loeys-Dietz syndrome 4 (ortholog); Usher syndrome (ortholog); FOUND IN aminoacyl-tRNA synthetase multienzyme complex (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: bifunctional glutamate/proline--tRNA ligase; Eprs; glutamyl-prolyl-tRNA synthetase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555203,550,558 - 3,606,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555203,550,558 - 3,606,015 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References


Genomics

Comparative Map Data
Eprs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555203,550,558 - 3,606,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555203,550,558 - 3,606,015 (+)NCBIChiLan1.0ChiLan1.0
EPRS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1219,968,600 - 220,046,530 (-)EnsemblGRCh38hg38GRCh38
GRCh381219,968,600 - 220,046,505 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371220,141,942 - 220,219,847 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371220,141,940 - 220,220,000 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,208,565 - 218,286,623 (-)NCBINCBI36hg18NCBI36
Build 341216,530,337 - 216,596,723NCBI
Celera1193,361,173 - 193,439,298 (-)NCBI
Cytogenetic Map1q41NCBI
HuRef1190,816,669 - 190,894,723 (-)NCBIHuRef
CHM1_11221,414,886 - 221,492,894 (-)NCBICHM1_1
Eprs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,093,614 - 185,160,557 (+)NCBIGRCm39mm39
GRCm381185,361,417 - 185,428,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,363,044 - 185,428,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,186,974 - 187,252,234 (+)NCBIGRCm37mm9NCBIm37
MGSCv361187,063,883 - 187,129,143 (+)NCBImm8
MGSCv361186,479,177 - 186,544,604 (+)NCBImm8
Celera1192,317,193 - 192,381,950 (+)NCBICelera
Cytogenetic Map1H5NCBI
Eprs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21396,901,548 - 96,971,966 (+)NCBI
Rnor_6.0 Ensembl13103,300,932 - 103,371,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.013103,300,911 - 103,371,651 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013107,973,665 - 108,044,298 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413101,375,656 - 101,448,175 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113101,564,698 - 101,637,217 (+)NCBI
Celera1396,415,061 - 96,484,921 (+)NCBICelera
Cytogenetic Map13q26NCBI
EPRS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11200,575,257 - 200,655,958 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1200,575,259 - 200,656,197 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01195,537,319 - 195,618,257 (-)NCBIMhudiblu_PPA_v0panPan3
EPRS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3814,754,632 - 14,823,621 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13814,754,628 - 14,823,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Eprs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366502,145,614 - 2,219,812 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPRS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl109,579,301 - 9,648,414 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1109,579,301 - 9,648,416 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,663,038 - 11,730,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPRS1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1259,534,747 - 9,618,119 (+)NCBI
ChlSab1.1 Ensembl259,534,114 - 9,618,141 (+)Ensembl
Eprs1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248353,635,829 - 3,695,875 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005528   ⟹   ENSCLAP00000005431
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555203,550,558 - 3,606,697 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000005529   ⟹   ENSCLAP00000005432
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555203,550,677 - 3,606,697 (+)Ensembl
RefSeq Acc Id: XM_005409277   ⟹   XP_005409334
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555203,550,558 - 3,606,015 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409334 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005409334   ⟸   XM_005409277
- Sequence:
RefSeq Acc Id: ENSCLAP00000005432   ⟸   ENSCLAT00000005529
RefSeq Acc Id: ENSCLAP00000005431   ⟸   ENSCLAT00000005528


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003851 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000005431 ENTREZGENE
Ensembl Transcript ENSCLAT00000005528 ENTREZGENE
NCBI Gene Eprs ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-20 Eprs1  glutamyl-prolyl-tRNA synthetase 1  Eprs  glutamyl-prolyl-tRNA synthetase  Symbol and/or name change 5135510 APPROVED