Slc6a5 (solute carrier family 6 member 5) - Rat Genome Database

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Gene: Slc6a5 (solute carrier family 6 member 5) Chinchilla lanigera
Analyze
Symbol: Slc6a5
Name: solute carrier family 6 member 5
RGD ID: 8882801
Description: ENCODES a protein that exhibits glycine transmembrane transporter activity (ortholog); glycine:sodium symporter activity (ortholog); INVOLVED IN glycine import across plasma membrane (ortholog); glycine transport (ortholog); neurotransmitter reuptake (ortholog); ASSOCIATED WITH Apnea (ortholog); brain disease (ortholog); Cryopyrin-Associated Periodic Syndromes (ortholog); FOUND IN dense core granule (ortholog); endosome (ortholog); glycinergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium- and chloride-dependent glycine transporter 2; solute carrier family 6 (neurotransmitter transporter), member 5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554761,380,869 - 1,433,005 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554761,380,869 - 1,433,005 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc6a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554761,380,869 - 1,433,005 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554761,380,869 - 1,433,005 (+)NCBIChiLan1.0ChiLan1.0
SLC6A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381120,599,608 - 20,659,285 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1120,599,594 - 20,659,285 (+)EnsemblGRCh38hg38GRCh38
GRCh371120,621,154 - 20,680,831 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,577,522 - 20,633,186 (+)NCBINCBI36Build 36hg18NCBI36
Build 341120,577,526 - 20,633,039NCBI
Celera1120,753,868 - 20,809,521 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1120,304,109 - 20,359,891 (+)NCBIHuRef
CHM1_11120,620,950 - 20,676,570 (+)NCBICHM1_1
T2T-CHM13v2.01120,720,301 - 20,780,085 (+)NCBIT2T-CHM13v2.0
Slc6a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39749,556,733 - 49,613,612 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl749,559,894 - 49,613,604 (+)EnsemblGRCm39 Ensembl
GRCm38749,906,984 - 49,963,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl749,910,146 - 49,963,856 (+)EnsemblGRCm38mm10GRCm38
MGSCv37757,165,669 - 57,214,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36749,778,790 - 49,831,883 (+)NCBIMGSCv36mm8
MGSCv36739,534,119 - 39,587,298 (+)NCBIMGSCv36mm8
Celera745,360,416 - 45,409,800 (+)NCBICelera
Cytogenetic Map7B4NCBI
cM Map731.71NCBI
Slc6a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81108,767,245 - 108,833,173 (+)NCBIGRCr8
mRatBN7.2199,645,389 - 99,697,016 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,645,389 - 99,697,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1104,999,473 - 105,051,092 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01113,471,390 - 113,523,011 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01106,793,636 - 106,845,259 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01105,270,418 - 105,336,369 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1105,284,753 - 105,336,363 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01106,333,982 - 106,385,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4199,741,713 - 99,793,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1199,819,823 - 99,871,411 (+)NCBI
Celera193,839,503 - 93,890,460 (+)NCBICelera
Cytogenetic Map1q22NCBI
SLC6A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2922,906,036 - 22,963,918 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11122,865,513 - 22,923,369 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01120,627,557 - 20,691,347 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11120,537,781 - 20,593,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1120,538,054 - 20,592,893 (+)Ensemblpanpan1.1panPan2
SLC6A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12142,581,931 - 42,639,870 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2142,581,965 - 42,639,585 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2142,059,192 - 42,115,260 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02143,704,400 - 43,760,475 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2143,704,391 - 43,760,224 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12142,705,998 - 42,761,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02142,882,046 - 42,937,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02143,263,792 - 43,319,870 (+)NCBIUU_Cfam_GSD_1.0
Slc6a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494742,346,038 - 42,402,922 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366541,525,843 - 1,576,220 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366541,525,843 - 1,576,220 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl238,767,501 - 38,826,783 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1238,767,447 - 38,826,891 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC6A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,345,697 - 44,404,709 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl144,350,099 - 44,402,396 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038141,681,408 - 141,732,095 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476611,853,973 - 11,910,595 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476611,853,979 - 11,910,666 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002173   ⟹   ENSCLAP00000002128
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554761,380,869 - 1,433,005 (+)Ensembl
RefSeq Acc Id: XM_013502900   ⟹   XP_013358354
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554761,380,869 - 1,433,005 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358354 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002128
  ENSCLAP00000002128.1
Reference Protein Sequences
RefSeq Acc Id: XP_013358354   ⟸   XM_013502900
- UniProtKB: A0A8C2UMY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002128   ⟸   ENSCLAT00000002173


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001544 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002173 ENTREZGENE
  ENSCLAT00000002173.1 UniProtKB/TrEMBL
InterPro Na/ntran_symport UniProtKB/TrEMBL
  SNS_sf UniProtKB/TrEMBL
NCBI Gene Slc6a5 ENTREZGENE
PANTHER PTHR11616 UniProtKB/TrEMBL
  SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2 UniProtKB/TrEMBL
Pfam SNF UniProtKB/TrEMBL
PRINTS NANEUSMPORT UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/TrEMBL
UniProt A0A8C2UMY5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Slc6a5  solute carrier family 6 member 5    solute carrier family 6 (neurotransmitter transporter), member 5  Symbol and/or name change 5135510 APPROVED