Pomc (proopiomelanocortin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pomc (proopiomelanocortin) Chinchilla lanigera
Analyze
Symbol: Pomc
Name: proopiomelanocortin
RGD ID: 8877656
Description: ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); calcium-mediated signaling (ortholog); cell-cell signaling (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; altered energy homeostasis pathway; altered melanocortin system pathway; ASSOCIATED WITH ACTH Syndrome, Ectopic (ortholog); acute kidney failure (ortholog); acute kidney tubular necrosis (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: pro-opiomelanocortin
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,217,363 - 7,220,386 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,217,233 - 7,220,401 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
ACTH Syndrome, Ectopic  (ISO)
acute kidney failure  (ISO)
acute kidney tubular necrosis  (ISO)
Acute Liver Failure  (ISO)
adrenal cortex disease  (ISO)
amnestic disorder  (ISO)
autistic disorder  (ISO)
bipolar disorder  (ISO)
Body Weight  (ISO)
Bradycardia  (ISO)
Burns  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Catalepsy  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral palsy  (ISO)
cholestasis  (ISO)
chondrocalcinosis  (ISO)
Cocaine-Related Disorders  (ISO)
congestive heart failure  (ISO)
constipation  (ISO)
Cushing Syndrome  (ISO)
cystitis  (ISO)
diabetes insipidus  (ISO)
diabetes mellitus  (ISO)
disease by infectious agent  (ISO)
disease of mental health  (ISO)
Edema  (ISO)
epilepsy  (ISO)
epilepsy with generalized tonic-clonic seizures  (ISO)
Experimental Liver Cirrhosis  (ISO)
eye disease  (ISO)
Eye Pain  (ISO)
facial paralysis  (ISO)
familial Mediterranean fever  (ISO)
fatty liver disease  (ISO)
Femur Head Necrosis  (ISO)
Fever  (ISO)
Gastrointestinal Diseases  (ISO)
genetic disease  (ISO)
glomerulonephritis  (ISO)
Gouty Arthritis  (ISO)
Hematuria  (ISO)
Hemorrhage  (ISO)
heroin dependence  (ISO)
Hirsutism  (ISO)
Hypercalciuria  (ISO)
Hypernatremia  (ISO)
Hyperphagia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypocalcemia  (ISO)
hypokalemia  (ISO)
Hypotension  (ISO)
Hypoxia  (ISO)
immune system disease  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
Kidney Calculi  (ISO)
kidney disease  (ISO)
long QT syndrome  (ISO)
melanoma  (ISO)
mental depression  (ISO)
multiple sclerosis  (ISO)
myasthenia gravis  (ISO)
Myocardial Ischemia  (ISO)
Myoclonic Epilepsies  (ISO)
Nausea  (ISO)
Necrosis  (ISO)
nephrocalcinosis  (ISO)
Neurogenic Inflammation  (ISO)
Nociceptive Pain  (ISO)
obesity  (ISO)
Oliguria  (ISO)
Opsoclonus-Myoclonus Syndrome  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
Pain  (ISO)
pancreas disease  (ISO)
penile disease  (ISO)
pituitary-dependent Cushing's disease  (ISO)
pneumonia  (ISO)
Postoperative Complications  (ISO)
Proopiomelanocortin Deficiency  (ISO)
proteinuria  (ISO)
Recurrence  (ISO)
renal cell carcinoma  (ISO)
restless legs syndrome  (ISO)
Rhabdomyoma  (ISO)
Sacroiliitis  (ISO)
severe acute respiratory syndrome  (ISO)
sick sinus syndrome  (ISO)
sleep disorder  (ISO)
subvalvular aortic stenosis  (ISO)
synovitis  (ISO)
urinary tract infection  (ISO)
visual epilepsy  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)
West syndrome  (ISO)
withdrawal disorder  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
altered energy homeostasis pathway  (ISO)
altered melanocortin system pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
melanocortin system pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
obesity pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
syndecan signaling pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

References


Genomics

Comparative Map Data
Pomc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,217,363 - 7,220,386 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,217,233 - 7,220,401 (-)NCBIChiLan1.0ChiLan1.0
POMC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl225,160,853 - 25,168,903 (-)EnsemblGRCh38hg38GRCh38
GRCh38225,160,860 - 25,168,580 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37225,383,729 - 25,391,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36225,237,226 - 25,245,063 (-)NCBINCBI36hg18NCBI36
Build 34225,295,438 - 25,303,103NCBI
Celera225,224,014 - 25,231,854 (-)NCBI
Cytogenetic Map2p23.3NCBI
HuRef225,121,466 - 25,129,306 (-)NCBIHuRef
CHM1_1225,313,607 - 25,321,447 (-)NCBICHM1_1
Pomc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,004,945 - 4,010,643 (+)NCBIGRCm39mm39
GRCm39 Ensembl124,004,951 - 4,010,642 (+)Ensembl
GRCm38123,954,945 - 3,960,643 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,954,951 - 3,960,642 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,954,951 - 3,960,618 (+)NCBIGRCm37mm9NCBIm37
MGSCv36123,954,967 - 3,960,634 (+)NCBImm8
Celera123,882,694 - 3,888,357 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.99NCBI
Pomc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2626,939,844 - 26,945,666 (+)NCBI
Rnor_6.0 Ensembl628,382,962 - 28,388,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0628,382,937 - 28,388,771 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0638,191,989 - 38,197,809 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,931,969 - 26,937,789 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1626,934,921 - 26,940,742 (+)NCBI
Celera626,415,706 - 26,421,526 (+)NCBICelera
RH 3.4 Map6117.99RGD
Cytogenetic Map6q14NCBI
POMC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A25,258,768 - 25,266,806 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A25,258,768 - 25,262,706 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A25,161,668 - 25,165,600 (-)NCBIMhudiblu_PPA_v0panPan3
POMC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11719,431,396 - 19,438,247 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1719,431,585 - 19,434,440 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1719,328,041 - 19,334,822 (-)NCBI
ROS_Cfam_1.01719,706,608 - 19,713,398 (-)NCBI
UMICH_Zoey_3.11719,440,669 - 19,447,445 (-)NCBI
UNSW_CanFamBas_1.01719,450,362 - 19,457,130 (-)NCBI
UU_Cfam_GSD_1.01719,496,844 - 19,503,629 (-)NCBI
Pomc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629263,774,289 - 63,781,377 (-)NCBI
SpeTri2.0NW_0049364937,060,747 - 7,065,276 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POMC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.13113,661,712 - 113,668,558 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23120,766,352 - 120,772,976 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POMC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11482,491,296 - 82,499,289 (+)NCBI
ChlSab1.1 Ensembl1482,494,323 - 82,499,447 (+)Ensembl
Vero_WHO_p1.0NW_02366604529,662,185 - 29,670,382 (-)NCBI
Pomc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247387,442,223 - 7,448,513 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014891   ⟹   ENSCLAP00000014732
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554697,217,363 - 7,220,386 (-)Ensembl
RefSeq Acc Id: XM_005400399   ⟹   XP_005400456
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554697,217,233 - 7,220,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013522557   ⟹   XP_013378011
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554697,217,233 - 7,218,151 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400456 (Get FASTA)   NCBI Sequence Viewer  
  XP_013378011 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005400456   ⟸   XM_005400399
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013378011   ⟸   XM_013522557
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000014732   ⟸   ENSCLAT00000014891


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010165 Ensembl
NCBI Gene Pomc ENTREZGENE