Pomc (proopiomelanocortin) - Rat Genome Database

Name: Pomc
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Pomc (proopiomelanocortin) Chinchilla lanigera

Analyze

Symbol:

Pomc

Name:

proopiomelanocortin

RGD ID:

8877656

Description:

ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); hormone activity (ortholog); signaling receptor binding (ortholog); INVOLVED IN calcium-mediated signaling (ortholog); cell-cell signaling (ortholog); cellular pigmentation (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; altered energy homeostasis pathway; altered melanocortin system pathway; ASSOCIATED WITH ACTH Syndrome, Ectopic (ortholog); acute kidney failure (ortholog); acute kidney tubular necrosis (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

pro-opiomelanocortin

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POMC (proopiomelanocortin)	NCBI	Ortholog
Mus musculus (house mouse):	Pomc (pro-opiomelanocortin-alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pomc (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POMC (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POMC (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pomc (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POMC (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POMC (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pomc (proopiomelanocortin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	7,217,363 - 7,220,386 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	7,217,233 - 7,220,401 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ACTH Syndrome, Ectopic (ISO)

acute kidney failure (ISO)

acute kidney tubular necrosis (ISO)

Acute Liver Failure (ISO)

adrenal cortex disease (ISO)

alcohol dependence (ISO)

alcohol use disorder (ISO)

amnestic disorder (ISO)

autistic disorder (ISO)

bipolar disorder (ISO)

Body Weight (ISO)

Bradycardia (ISO)

Burns (ISO)

calcinosis (ISO)

Cardiomegaly (ISO)

cardiomyopathy (ISO)

Catalepsy (ISO)

Cerebral Hemorrhage (ISO)

cerebral palsy (ISO)

cholestasis (ISO)

chondrocalcinosis (ISO)

Cocaine-Related Disorders (ISO)

congestive heart failure (ISO)

Constipation (ISO)

Cushing Syndrome (ISO)

cystitis (ISO)

depressive disorder (ISO)

diabetes insipidus (ISO)

diabetes mellitus (ISO)

disease by infectious agent (ISO)

disease of mental health (ISO)

Edema (ISO)

epilepsy (ISO)

epilepsy with generalized tonic-clonic seizures (ISO)

Experimental Arthritis (ISO)

Experimental Liver Cirrhosis (ISO)

eye disease (ISO)

Eye Pain (ISO)

facial paralysis (ISO)

familial mediterranean fever (ISO)

Femur Head Necrosis (ISO)

Fever (ISO)

gastrointestinal system disease (ISO)

genetic disease (ISO)

glomerulonephritis (ISO)

Gouty Arthritis (ISO)

Hematuria (ISO)

Hemorrhage (ISO)

heroin dependence (ISO)

Hirsutism (ISO)

Hypercalciuria (ISO)

Hypernatremia (ISO)

Hyperphagia (ISO)

hypertension (ISO)

hypertrophic cardiomyopathy (ISO)

Hypocalcemia (ISO)

hypokalemia (ISO)

Hypotension (ISO)

Hypoxia (ISO)

immune system disease (ISO)

Inflammation (ISO)

inflammatory bowel disease (ISO)

Kidney Calculi (ISO)

kidney disease (ISO)

long QT syndrome (ISO)

melanoma (ISO)

multiple sclerosis (ISO)

myasthenia gravis (ISO)

Myocardial Ischemia (ISO)

Myoclonic Epilepsies (ISO)

Nausea (ISO)

Necrosis (ISO)

nephrocalcinosis (ISO)

Neurogenic Inflammation (ISO)

Nociceptive Pain (ISO)

obesity (ISO)

Oliguria (ISO)

opioid abuse (ISO)

Opsoclonus-Myoclonus Syndrome (ISO)

osteoarthritis (ISO)

osteoporosis (ISO)

Pain (ISO)

pancreas disease (ISO)

penile disease (ISO)

pituitary-dependent Cushing's disease (ISO)

pneumonia (ISO)

Postoperative Complications (ISO)

Proopiomelanocortin Deficiency (ISO)

proteinuria (ISO)

Recurrence (ISO)

renal cell carcinoma (ISO)

restless legs syndrome (ISO)

Rhabdomyoma (ISO)

Sacroiliitis (ISO)

severe acute respiratory syndrome (ISO)

sick sinus syndrome (ISO)

sleep disorder (ISO)

steatotic liver disease (ISO)

stress-related disorder (ISO)

subvalvular aortic stenosis (ISO)

synovitis (ISO)

Tatton-Brown-Rahman syndrome (ISO)

urinary tract infection (ISO)

Weight Gain (ISO)

Weight Loss (ISO)

West syndrome (ISO)

withdrawal disorder (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-mediated signaling (ISO)

cell-cell signaling (ISO)

cellular pigmentation (ISO)

cortisol secretion (ISO)

generation of precursor metabolites and energy (ISO)

glucose homeostasis (ISO)

negative regulation of tumor necrosis factor production (ISO)

positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISO)

positive regulation of neutrophil mediated killing of fungus (ISO)

positive regulation of oxytocin production (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of appetite (ISO)

regulation of blood pressure (ISO)

regulation of corticosterone secretion (ISO)

regulation of glycogen metabolic process (ISO)

response to alcohol (ISO)

response to ethanol (ISO)

response to immobilization stress (ISO)

response to melanocyte-stimulating hormone (ISO)

signal transduction (ISO)

Cellular Component

cytoplasm (ISO)

extracellular region (ISO)

extracellular space (ISO)

peroxisomal matrix (ISO)

peroxisome (ISO)

secretory granule (ISO)

Molecular Function

G protein-coupled receptor binding (ISO)

hormone activity (ISO)

protein binding (ISO)

signaling receptor binding (ISO)

type 1 melanocortin receptor binding (ISO)

type 3 melanocortin receptor binding (ISO)

type 4 melanocortin receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

alfentanil pharmacodynamics pathway (ISO)

altered energy homeostasis pathway (ISO)

altered melanocortin system pathway (ISO)

bupivacaine pharmacodynamics pathway (ISO)

buprenorphine pharmacodynamics pathway (ISO)

chloroprocaine pharmacodynamics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

cocaine pharmacodynamics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

diphenoxylate pharmacodynamics pathway (ISO)

escitalopram pharmacodynamics pathway (ISO)

ethylmorphine pharmacodynamics pathway (ISO)

fentanyl pharmacodynamics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

heroin pharmacodynamics pathway (ISO)

hydrocodone pharmacodynamics pathway (ISO)

hydromorphone pharmacodynamics pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

levacetylmethadol pharmacodynamics pathway (ISO)

levobupivacaine phgarmacodynamics pathway (ISO)

levorphanol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

melanocortin system pathway (ISO)

mepivacaine pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

nalbuphine pharmacodynamics pathway (ISO)

naloxone pharmacodynamics pathway (ISO)

naltrexone pharmacodynamics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

obesity pathway (ISO)

oxybuprocaine pharmacodynamics pathway (ISO)

oxycodone pharmacodynamics pathway (ISO)

oxymorphone pharmacodynamics pathway (ISO)

pentazocine pharmacodynamics pathway (ISO)

prilocaine pharmacodynamics pathway (ISO)

procaine pharmacodynamics pathway (ISO)

remifentanil pharmacodynamics pathway (ISO)

ropivacaine pharmacodynamics pathway (ISO)

syndecan signaling pathway (ISO)

tramadol pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Pomc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	7,217,363 - 7,220,386 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	7,217,233 - 7,220,401 (-)	NCBI	ChiLan1.0	ChiLan1.0

POMC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	25,160,860 - 25,168,580 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	25,160,853 - 25,168,903 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	25,383,729 - 25,391,449 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	25,237,226 - 25,245,063 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	25,295,438 - 25,303,103	NCBI
Celera	2	25,224,014 - 25,231,854 (-)	NCBI		Celera
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	25,121,466 - 25,129,306 (-)	NCBI		HuRef
CHM1_1	2	25,313,607 - 25,321,447 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	25,195,313 - 25,203,034 (-)	NCBI		T2T-CHM13v2.0

Pomc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	4,004,945 - 4,010,643 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	4,004,951 - 4,010,642 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	3,954,945 - 3,960,643 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	3,954,951 - 3,960,642 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	3,954,951 - 3,960,618 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	3,954,967 - 3,960,634 (+)	NCBI		MGSCv36	mm8
Celera	12	3,882,694 - 3,888,357 (+)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	1.99	NCBI

Pomc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	32,659,137 - 32,665,175 (+)	NCBI		GRCr8
mRatBN7.2	6	26,939,844 - 26,945,666 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	26,939,837 - 26,945,664 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	27,232,130 - 27,237,950 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	27,548,037 - 27,553,857 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	27,026,040 - 27,031,858 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	28,382,937 - 28,388,771 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	28,382,962 - 28,388,967 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	38,191,989 - 38,197,809 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	26,931,969 - 26,937,789 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	26,934,921 - 26,940,742 (+)	NCBI
Celera	6	26,415,706 - 26,421,526 (+)	NCBI		Celera
RH 3.4 Map	6	117.99	RGD
Cytogenetic Map	6	q14	NCBI

POMC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	101,353,171 - 101,357,103 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	101,357,136 - 101,361,068 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	25,161,668 - 25,165,600 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	25,258,768 - 25,266,806 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	25,258,768 - 25,262,706 (-)	Ensembl	panpan1.1		panPan2

POMC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	19,431,396 - 19,438,247 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	19,431,585 - 19,434,440 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	19,328,041 - 19,334,822 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	19,706,608 - 19,713,398 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	19,706,796 - 19,714,128 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	19,440,669 - 19,447,445 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	19,450,362 - 19,457,130 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	19,496,844 - 19,503,629 (-)	NCBI		UU_Cfam_GSD_1.0

Pomc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	63,774,289 - 63,781,377 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	7,061,587 - 7,065,109 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	7,060,747 - 7,065,276 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POMC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	113,661,004 - 113,670,418 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	113,661,712 - 113,668,558 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	120,766,352 - 120,772,976 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POMC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	82,491,296 - 82,499,289 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	82,494,323 - 82,499,447 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	29,662,185 - 29,670,382 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pomc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	7,442,292 - 7,445,020 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	7,442,223 - 7,448,513 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005400399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013522557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01052411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01002960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000014891 ⟹ ENSCLAP00000014732

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955469	7,217,363 - 7,220,386 (-)	Ensembl

RefSeq Acc Id:

XM_005400399 ⟹ XP_005400456

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955469	7,217,233 - 7,220,401 (-)	NCBI

Sequence:

show sequence

CCTGCCACCTGGAAGATGCCGAGATTGTGCTACAGCTGCTCTGGGGCCCTGCTGCTGGCCTTGC
TACTTCAGGCCTCCATGGAAGTGTGCGGCTGGTGCCTGGAAAGCAGCCAGTGTCAGGACCTCAC
CACAGAAAGAAACCTGCTGGAGTGCATCCGGGCCTGCAAACCCGACCTCTCGGCCGAGACGCCT
GTGTTTCCGGGGAACGGCGACGAGCAACCGCTGACAGAGAACCCCCGGAAGTACGTCATGGGCC
ACTTCCGCTGGGACCGCTTCGGCCGCCGGAACAGCAGCGGCGGCGGCGGTGCGAGCCGGAAGCG
CGAAGAGGAGGTTGCGGCGGGCGAAGGCCGCGTCCCGCTGCCCGCTGGCGATCCTGAGTTCCGC
GGCGATGGCGCCGAGCCGGGCCCTCACGAGGGCAAGCGCTCCTACTCCATGGAGCACTTCCGCT
GGGGCAAGCCGGTGGGCAAGAAGCGGCGCCCGGTGAAGGTGTACCCGAACGGCGCGGAGGACGA
GTCGGCCGAGGCCTTTCCGCTCGAGTTCAAGAGGGAGCTGGCCGGGGAGCGGCCCGCGGCGGCG
CCCGGCCCCGACGAGCTGGAGCTCGGCGAGGCGGCCGCGGCCGAGAAGAAGGACGACGGGCCCT
ATCGCATGGAGCACTTCCGCTGGGGCACGCCGCGCAAGGACAAGCGCTACGGCGGCTTCATGAG
CTCGGAGAAGAGCCAGACGCCGCTGGTGACGCTGTTCAAGAACGCCATCATCAAGAACGCCCAC
AAGAAGGGCCAGTGAGGCGCGGGCCCGGGCCTGCCCGCCCGCCCGCCCGAGAGGCAGTCCGCCC
GCAGCCCCTGCCCGCCAGCCCTCCATCGCCTTCTGGTCACTGAAGCTGCCTGTAGTTAGGAAAT
AAAGCCTGTCAAATTTC

hide sequence

RefSeq Acc Id:

XM_013522557 ⟹ XP_013378011

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955469	7,217,233 - 7,218,151 (-)	NCBI

Sequence:

show sequence

TGAGACAGAGATGACATGACATCGGTGGGCCCACATACTGGGCAGGCTGGCGTCGAGGAGTGCA
TCCGGGCCTGCAAACCCGACCTCTCGGCCGAGACGCCTGTGTTTCCGGGGAACGGCGACGAGCA
ACCGCTGACAGAGAACCCCCGGAAGTACGTCATGGGCCACTTCCGCTGGGACCGCTTCGGCCGC
CGGAACAGCAGCGGCGGCGGCGGTGCGAGCCGGAAGCGCGAAGAGGAGGTTGCGGCGGGCGAAG
GCCGCGTCCCGCTGCCCGCTGGCGATCCTGAGTTCCGCGGCGATGGCGCCGAGCCGGGCCCTCA
CGAGGGCAAGCGCTCCTACTCCATGGAGCACTTCCGCTGGGGCAAGCCGGTGGGCAAGAAGCGG
CGCCCGGTGAAGGTGTACCCGAACGGCGCGGAGGACGAGTCGGCCGAGGCCTTTCCGCTCGAGT
TCAAGAGGGAGCTGGCCGGGGAGCGGCCCGCGGCGGCGCCCGGCCCCGACGAGCTGGAGCTCGG
CGAGGCGGCCGCGGCCGAGAAGAAGGACGACGGGCCCTATCGCATGGAGCACTTCCGCTGGGGC
ACGCCGCGCAAGGACAAGCGCTACGGCGGCTTCATGAGCTCGGAGAAGAGCCAGACGCCGCTGG
TGACGCTGTTCAAGAACGCCATCATCAAGAACGCCCACAAGAAGGGCCAGTGAGGCGCGGGCCC
GGGCCTGCCCGCCCGCCCGCCCGAGAGGCAGTCCGCCCGCAGCCCCTGCCCGCCAGCCCTCCAT
CGCCTTCTGGTCACTGAAGCTGCCTGTAGTTAGGAAATAAAGCCTGTCAAATTTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005400456	(Get FASTA)	NCBI Sequence Viewer
	XP_013378011	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000014732.1

RefSeq Acc Id:

XP_005400456 ⟸ XM_005400399

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPRLCYSCSGALLLALLLQASMEVCGWCLESSQCQDLTTERNLLECIRACKPDLSAETPVFPGN
GDEQPLTENPRKYVMGHFRWDRFGRRNSSGGGGASRKREEEVAAGEGRVPLPAGDPEFRGDGAE
PGPHEGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELAGERPAAAPGPDE
LELGEAAAAEKKDDGPYRMEHFRWGTPRKDKRYGGFMSSEKSQTPLVTLFKNAIIKNAHKKGQ

hide sequence

RefSeq Acc Id:

XP_013378011 ⟸ XM_013522557

- Peptide Label:

isoform X2

- Sequence:

show sequence

MTSVGPHTGQAGVEECIRACKPDLSAETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNSSG
GGGASRKREEEVAAGEGRVPLPAGDPEFRGDGAEPGPHEGKRSYSMEHFRWGKPVGKKRRPVKV
YPNGAEDESAEAFPLEFKRELAGERPAAAPGPDELELGEAAAAEKKDDGPYRMEHFRWGTPRKD
KRYGGFMSSEKSQTPLVTLFKNAIIKNAHKKGQ

hide sequence

RefSeq Acc Id:

ENSCLAP00000014732 ⟸ ENSCLAT00000014891

Protein Domains

Opiodes neuropeptide Pro-opiomelanocortin N-terminal Pro-opiomelanocortin/corticotropin ACTH central

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010165	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000014891.1	UniProtKB/TrEMBL
InterPro	Mcrtin_ACTH_cent	UniProtKB/TrEMBL
	Melanocortin_N	UniProtKB/TrEMBL
	Opioid_neuropept	UniProtKB/TrEMBL
	PMOC	UniProtKB/TrEMBL
NCBI Gene	Pomc	ENTREZGENE
PANTHER	PRO-OPIOMELANOCORTIN	UniProtKB/TrEMBL
	PRO-OPIOMELANOCORTIN	UniProtKB/TrEMBL
Pfam	ACTH_domain	UniProtKB/TrEMBL
	NPP	UniProtKB/TrEMBL
	Op_neuropeptide	UniProtKB/TrEMBL
PRINTS	MELANOCORTIN	UniProtKB/TrEMBL
SMART	ACTH_domain	UniProtKB/TrEMBL
	NPP	UniProtKB/TrEMBL
	Op_neuropeptide	UniProtKB/TrEMBL
UniProt	A0A8C2VHG1_CHILA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)