Arhgef10 (Rho guanine nucleotide exchange factor 10) - Rat Genome Database
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Gene: Arhgef10 (Rho guanine nucleotide exchange factor 10) Chinchilla lanigera
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Symbol: Arhgef10
Name: Rho guanine nucleotide exchange factor 10
RGD ID: 8877206
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); kinesin binding (ortholog); INVOLVED IN activation of GTPase activity (ortholog); centrosome duplication (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH axonal neuropathy (ortholog); Charcot-Marie-Tooth disease (ortholog); myopathy (ortholog); FOUND IN centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: Rho guanine nucleotide exchange factor (GEF) 10
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540357,818,837 - 57,907,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (ISO)

Molecular Function

References


Genomics

Comparative Map Data
Arhgef10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540357,818,837 - 57,907,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl81,823,926 - 1,958,641 (+)EnsemblGRCh38hg38GRCh38
GRCh3881,823,926 - 1,958,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3781,772,092 - 1,906,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3681,759,556 - 1,894,214 (+)NCBINCBI36hg18NCBI36
Build 3481,808,165 - 1,894,206NCBI
Celera81,715,545 - 1,849,273 (+)NCBI
Cytogenetic Map8p23.3NCBI
HuRef81,586,197 - 1,723,095 (+)NCBIHuRef
CHM1_181,772,104 - 1,906,332 (+)NCBICHM1_1
Arhgef10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39814,956,405 - 15,051,085 (+)NCBIGRCm39mm39
GRCm39 Ensembl814,961,663 - 15,051,085 (+)Ensembl
GRCm38814,906,412 - 15,001,085 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl814,911,663 - 15,001,085 (+)EnsemblGRCm38mm10GRCm38
MGSCv37814,911,717 - 15,001,085 (+)NCBIGRCm37mm9NCBIm37
MGSCv36814,928,877 - 15,000,415 (+)NCBImm8
Celera815,075,995 - 15,165,401 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
Arhgef10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21674,647,147 - 74,738,784 (-)NCBI
Rnor_6.0 Ensembl1679,725,643 - 79,793,619 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01679,725,629 - 79,817,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01679,302,340 - 79,392,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41679,458,304 - 79,547,225 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1672,465,044 - 72,554,359 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
ARHGEF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.181,747,801 - 1,862,917 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl81,724,413 - 1,862,917 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v085,381,357 - 5,541,094 (-)NCBIMhudiblu_PPA_v0panPan3
ARHGEF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1654,293,435 - 54,347,555 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11654,293,534 - 54,378,706 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Arhgef10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366151,012,009 - 1,103,468 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11533,370,093 - 33,465,852 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21537,931,757 - 37,986,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.181,487,076 - 1,620,387 (+)NCBI
ChlSab1.1 Ensembl81,502,226 - 1,620,389 (+)Ensembl
Arhgef10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624861992,824 - 1,083,048 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023840   ⟹   ENSCLAP00000023616
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540357,818,837 - 57,899,525 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023841   ⟹   ENSCLAP00000023617
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540357,818,837 - 57,899,525 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023842   ⟹   ENSCLAP00000023618
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540357,820,010 - 57,907,324 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000023843   ⟹   ENSCLAP00000023619
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540357,820,991 - 57,879,436 (-)Ensembl
RefSeq Acc Id: XM_013515006   ⟹   XP_013370460
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515009   ⟹   XP_013370463
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515012   ⟹   XP_013370466
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013515017   ⟹   XP_013370471
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540357,820,003 - 57,907,324 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013370460 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370463 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370466 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370471 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013370471   ⟸   XM_013515017
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013370466   ⟸   XM_013515012
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013370463   ⟸   XM_013515009
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013370460   ⟸   XM_013515006
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000023619   ⟸   ENSCLAT00000023843
RefSeq Acc Id: ENSCLAP00000023617   ⟸   ENSCLAT00000023841
RefSeq Acc Id: ENSCLAP00000023618   ⟸   ENSCLAT00000023842
RefSeq Acc Id: ENSCLAP00000023616   ⟸   ENSCLAT00000023840


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016199 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000023616 ENTREZGENE
  ENSCLAP00000023617 ENTREZGENE
  ENSCLAP00000023618 ENTREZGENE
Ensembl Transcript ENSCLAT00000023840 ENTREZGENE
  ENSCLAT00000023841 ENTREZGENE
  ENSCLAT00000023842 ENTREZGENE
NCBI Gene Arhgef10 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Arhgef10  Rho guanine nucleotide exchange factor 10    Rho guanine nucleotide exchange factor (GEF) 10  Symbol and/or name change 5135510 APPROVED