Fes (FES proto-oncogene, tyrosine kinase)

Gene: Fes (FES proto-oncogene, tyrosine kinase) Chinchilla lanigera

Analyze

Symbol:

Fes

Name:

FES proto-oncogene, tyrosine kinase

RGD ID:

8873474

Description:

ENCODES a protein that exhibits immunoglobulin receptor binding (ortholog); microtubule binding (ortholog); non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN cardiac muscle cell proliferation (ortholog); cellular response to vitamin D (ortholog); centrosome cycle (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Bloom syndrome (ortholog); coronary artery disease (ortholog); D-2-hydroxyglutaric aciduria 2 (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytoplasmic vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

feline sarcoma oncogene; tyrosine-protein kinase Fes/Fps

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	14,948,123 - 14,960,005 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	14,948,121 - 14,959,035 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

coronary artery disease (ISO)

D-2-hydroxyglutaric aciduria 2 (ISO)

esophagus squamous cell carcinoma (ISO)

female breast cancer (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

lung adenocarcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac muscle cell proliferation (ISO)

cellular response to vitamin D (ISO)

centrosome cycle (ISO)

microtubule bundle formation (ISO)

myoblast proliferation (ISO)

positive regulation of microtubule polymerization (ISO)

positive regulation of monocyte differentiation (ISO)

positive regulation of myeloid cell differentiation (ISO)

positive regulation of neuron projection development (ISO)

regulation of cell adhesion (ISO)

regulation of cell differentiation (ISO)

regulation of cell motility (ISO)

regulation of cell population proliferation (ISO)

regulation of cell shape (ISO)

regulation of mast cell degranulation (ISO)

Cellular Component

cytoplasm (ISO)

cytoplasmic side of plasma membrane (ISO)

cytoplasmic vesicle (ISO)

focal adhesion (ISO)

microtubule cytoskeleton (ISO)

Molecular Function

immunoglobulin receptor binding (ISO)

microtubule binding (ISO)

non-membrane spanning protein tyrosine kinase activity (ISO)

phosphatidylinositol binding (ISO)

protein binding (ISO)

protein kinase activity (ISO)

protein tyrosine kinase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-4 signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Fes
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	14,948,123 - 14,960,005 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	14,948,121 - 14,959,035 (+)	NCBI	ChiLan1.0	ChiLan1.0

FES
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	90,884,504 - 90,895,776 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	90,883,695 - 90,895,776 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	91,427,734 - 91,439,006 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	89,228,713 - 89,240,010 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	89,228,712 - 89,240,010	NCBI
Celera	15	67,836,636 - 67,847,969 (+)	NCBI		Celera
Cytogenetic Map	15	q26.1	NCBI
HuRef	15	67,539,170 - 67,550,515 (+)	NCBI		HuRef
CHM1_1	15	91,269,239 - 91,280,594 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	88,643,915 - 88,655,365 (+)	NCBI		T2T-CHM13v2.0

Fes
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	80,027,506 - 80,037,702 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	80,027,504 - 80,037,694 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	80,377,758 - 80,387,954 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	80,377,756 - 80,387,946 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	87,522,644 - 87,532,832 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	80,251,286 - 80,260,905 (-)	NCBI		MGSCv36	mm8
Celera	7	77,777,722 - 77,787,907 (-)	NCBI		Celera
Cytogenetic Map	7	D2	NCBI
cM Map	7	45.65	NCBI

Fes
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	143,746,945 - 143,756,181 (-)	NCBI		GRCr8
mRatBN7.2	1	134,337,698 - 134,346,934 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	134,337,698 - 134,346,934 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	142,246,565 - 142,255,805 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	149,415,959 - 149,425,199 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	142,333,966 - 142,343,206 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	142,174,648 - 142,183,884 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	142,174,648 - 142,183,884 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	143,127,277 - 143,136,513 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	136,199,523 - 136,208,759 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	126,397,304 - 126,406,534 (-)	NCBI		Celera
Cytogenetic Map	1	q31	NCBI

FES
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	80,437,700 - 80,449,677 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	84,135,731 - 84,147,865 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	69,576,936 - 69,588,834 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	88,774,967 - 88,786,965 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	88,774,965 - 88,786,965 (+)	Ensembl	panpan1.1		panPan2

FES
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	53,346,975 - 53,356,547 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	53,347,012 - 53,356,516 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	55,984,668 - 55,994,302 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	53,763,060 - 53,772,711 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	53,763,067 - 53,772,745 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	53,282,201 - 53,291,832 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	53,493,421 - 53,503,070 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	53,833,898 - 53,843,534 (-)	NCBI		UU_Cfam_GSD_1.0

Fes
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	130,199,476 - 130,210,580 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	16,123,779 - 16,135,044 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	16,123,938 - 16,135,044 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FES
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	53,472,947 - 53,485,082 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	53,472,947 - 53,485,084 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	58,504,744 - 58,516,272 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FES
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	8,967,542 - 8,979,475 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	8,965,997 - 8,979,361 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	37,746,110 - 37,758,650 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fes
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	17,359,196 - 17,372,712 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624768	17,360,602 - 17,372,563 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005381509	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005381510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013512503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01017292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01008856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000013763 ⟹ ENSCLAP00000013608

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955416	14,948,123 - 14,960,005 (+)	Ensembl

RefSeq Acc Id:

XM_005381509 ⟹ XP_005381566

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955416	14,948,123 - 14,959,035 (+)	NCBI

Sequence:

show sequence

AGAGCTGGCGCCGGAGCTCTCCTTGGGGAATCCAGCGGGTGGGGAGGGCCAGGACTAGCTTCCC
CAGTCCCTCTCTGGGCGCTGAGACCCTGCCTTCACAGCCTTCAGACAAGTTGGCTGCCCTGAGC
CAGACCCCTGCGCCCACCCCGCCCACCTCAGGCCCCGTCCGCAGGGTCCCGGACTCGCTGGCCT
GGGGAGTGAGGGCCTGCCCCACAGGCCTCTCCCCTCCGCTCTCGGCCATTCCCCCTCAGCCTCC
TCCTCCCTTCCGTTTCCGAGGGAGGGAGGCTGCCGTGGCCCAGCGTGGGGCCGGGGGCCGGTGG
GGCTCGCCCGCCCCTTCCCCTCGGCCCGCCCCGCCTGGGCCAACTGAAACCGCGGGAGGAGGAA
GCACCCAACCAGGAACTGGCCGGGGTTGGCGCGGGCCCGAGTAGGTCCACAGCCACCCAGGAGC
AGGAGCAGCTGCTTGCAAGGAACGCCAGCATGGGCTTCTCCTCGGAGCTGTGCAGCCCCCAGGG
CCACGGGGCAGTGCAGCAGATGCAGGAAGCTGAGCTTCGCTTGCTGGAGGGCATGAGGAAATGG
ATGGCCCAGCGGGTCAAGAGCGACCGGGAATATGCGGGGCTGCTCCACCACATGTCCCTGCAGG
ACGCCGGGGGCCAGAGCCGGAACAGCGGCCTGGATAGCCCCATCAGCCAGTCCTGGGCTGAGAT
CACCAGCCAGACCGAGGGACTGAGCCGAGTGCTGCGGCAGCACGCGGAAGACCTGAACTCAGGG
CCGCTGAGCAAGCTGAGCCTGCTGATCCGGGAGCGGCAGCAGCTGCGTAAGACCTACAGCGAGC
AGTGGCAGCAACTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGTTGAAGAG
CCAGTACCGAGCCCTGGCCCGGGACAGCACCCAAGCCAGACGCAAGTACCAGGAGGCCAGCAAA
GACAAGGACCGGGACAAGGCCAAGGACAAGTACGTGCGCAGCCTGTGGAAGCTCTTTGCCCACC
ACAACCGCTATGTGCTGGGCGTGCGGGCTGCACAGCTGCACCACCAGCACCACCACCAGCTCAT
GCTGCCCAGCTTGCTGCAGTCCCTGCAGGACCTGCACGAGGAGATGGCACACGTGCTGAAGGAG
ATCCTGCAGGAATACCTAGAGATTAGCAGCCTGGTGCAGGATGAGGTGATGGCCATTCACCGGG
AGATGGCCACAGCTGCGGCCCGCATCCAACCTGAGGCCGAGTACCAGGGTTTCCTGCGACAGTA
TGGCTCCGTCCCAGATGTCCCGCCCTGCGTCACCTTCGATGAGTCGCTGCTTGAGGAGGGTGAG
CAGCTGGAGCCTGGGGAGCTGCAGCTGAACGAGCTGACCGTGGAGAGCGTGCAGCACACGCTCA
CTTCAGTGACGGATGACCTGGCAGTGGCCACCGAGACCATGCTAAGCCGGCAGGAGGCAGTCAA
CCAGCTGCAGCGAGAGCTCCGGAGTGAGGAGCAGAGCACCCACCCCCGGGAGCGGGTGCAGCTA
CTGGGCAAGAGGCAGGCGCTACACGAGGCACTGCAGGGGCTGCAGGTCGCACTGTGCAGCCAGG
CCAAGCTGCAGGCCCAGCAGGAGCTGCTACAGACCAAGCTGGAGCAGCTGGGCCCCGGCGAGCC
CCCAGCTGTGCTGCTCCTGCAGGACGATCGCCACTCCACCTCGTCCTCGGAGCAGGAGCGAGAG
GGGGGAAGGACGCCCACGCTGGAGATCATCAAGAGCCACATCTCGGGAATCTTCCGCCCCAAGT
TCTCGCTCCCCCCACCGCTGCAGCTGGTTCCTGAGGTGCAGAAGCCCCTGCATGAGCAGCTGTG
GTACCACGGGGCCATCCCGCGGGCGGAGGTGGCCGAGCTGCTTACGAACTCCGGGGACTTCCTT
GTGCGGGAGAGCCAGGGCAAGCAGGAGTATGTGCTGTCCGTGCTGTGGGACGGCCTGCCACGCC
ACTTTATCATCCAGTCCTCCGACAACCTATACCGCCTGGAAGGTGATGGCTTCCCCAGCATCCC
CTTGCTCATTGACCACCTGCTCTGCTCCCAGCAGCCTCTCACCAAGAAGAGCGGTGTTGTTCTG
TATAGGGCAGTCCCCAAGGACAAGTGGGTGCTGAACCACGAGGACTTGGTGTTGGGCGAGCAGA
TTGGGAGGGGCAACTTTGGCGAAGTGTTCAGTGGGCGTCTGCGAGCCGACAACACGCCAGTGGC
AGTGAAGTCTTGTCGGGAGACGCTCCCGCCTGACCTCAAGGCCAAGTTCCTGCAAGAAGCCAGG
ATCCTGAAGCAGTACAGCCACCCCAACATCGTGCGGCTCATCGGGGTCTGCACGCAGAAGCAGC
CCATCTACATCGTCATGGAGCTGGTGCAGGGGGGCGACTTCCTGACCTTCCTGCGGACCGAGGG
AGCCCGCCTTCGCATGAAGACACTGCTGCAGATGGTGGGGGACGCGGCCGCGGGTATGGAGTAC
TTGGAGAGCAAGTGCTGCATCCACAGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGA
ATGTTTTGAAGATCAGTGACTTTGGGATGTCCCGGGAGGAGGCCGATGGGGTCTACGCAGCCTC
AGGGGGCCTCAGACAAGTCCCCGTGAAGTGGACTGCCCCTGAGGCCCTTAACTACGGCCGCTAC
TCCTCGGAGAGCGATGTGTGGAGCTTTGGCATCTTGCTTTGGGAGACCTTCAGCCTGGGGGCCT
CGCCCTACCCCAACCTCAGCAACCAGCAGACACGGGAGTTCGTGGAGAAGGGGGGTCGCCTGCC
CTGCCCGGAGCTGTGTCCTGACGCGGTGTTCCGGCTCATGGAGCAGTGCTGGGCCTACGAACCT
GTGCAGCGGCCCAGCTTCAGCACCATCTCTCAGGAGCTGCAGAGTATCCGGAAGCGGCATCGGT
GAGGCTGGGGTCGCTGCAGGCCGCAGTGTACCTCCTCCTCTGCAGCGCCCACCCTCACCAAGGG
ACAGCAGCCTGCCATCCTGGGATCCTGCCCCCAGCACCCCTGCTGCTGCAGGGACAGCCCCAGG
TCCGTTCTGGACTCTGCTCCTGCCGGGTGTCCTTCCTTGGACAGAAACAATAAAACCACTTGTG
CCCATCA

hide sequence

RefSeq Acc Id:

XM_005381510 ⟹ XP_005381567

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955416	14,948,123 - 14,959,035 (+)	NCBI

Sequence:

show sequence

AGAGCTGGCGCCGGAGCTCTCCTTGGGGAATCCAGCGGGTGGGGAGGGCCAGGACTAGCTTCCC
CAGTCCCTCTCTGGGCGCTGAGACCCTGCCTTCACAGCCTTCAGACAAGTTGGCTGCCCTGAGC
CAGACCCCTGCGCCCACCCCGCCCACCTCAGGCCCCGTCCGCAGGGTCCCGGACTCGCTGGCCT
GGGGAGTGAGGGCCTGCCCCACAGGCCTCTCCCCTCCGCTCTCGGCCATTCCCCCTCAGCCTCC
TCCTCCCTTCCGTTTCCGAGGGAGGGAGGCTGCCGTGGCCCAGCGTGGGGCCGGGGGCCGGTGG
GGCTCGCCCGCCCCTTCCCCTCGGCCCGCCCCGCCTGGGCCAACTGAAACCGCGGGAGGAGGAA
GCACCCAACCAGGAACTGGCCGGGGTTGGCGCGGGCCCGAGTAGGTCCACAGCCACCCAGGAGC
AGGAGCAGCTGCTTGCAAGGCCGCTGAAGCTGCCTCACCCCAGTGACGGCCTCTTTACTGTCCC
CAGAACGCCAGCATGGGCTTCTCCTCGGAGCTGTGCAGCCCCCAGGGCCACGGGGCAGTGCAGC
AGATGCAGGAAGCTGAGCTTCGCTTGCTGGAGGGCATGAGGAAATGGATGGCCCAGCGGGTCAA
GAGCGACCGGGAATATGCGGGGCTGCTCCACCACATGTCCCTGCAGGACGCCGGGGGCCAGAGC
CGGAACAGCGGCCTGGATAGCCCCATCAGCCAGTCCTGGGCTGAGATCACCAGCCAGACCGAGG
GACTGAGCCGAGTGCTGCGGCAGCACGCGGAAGACCTGAACTCAGGGCCGCTGAGCAAGCTGAG
CCTGCTGATCCGGGAGCGGCAGCAGCTGCGTAAGACCTACAGCGAGCAGTGGCAGCAACTGCAG
CAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGTTGAAGAGCCAGTACCGAGCCCTGG
CCCGGGACAGCACCCAAGCCAGACGCAAGTACCAGGAGGCCAGCAAAGACAAGGACCGGGACAA
GGCCAAGGACAAGTACGTGCGCAGCCTGTGGAAGCTCTTTGCCCACCACAACCGCTATGTGCTG
GGCGTGCGGGCTGCACAGCTGCACCACCAGCACCACCACCAGCTCATGCTGCCCAGCTTGCTGC
AGTCCCTGCAGGACCTGCACGAGGAGATGGCACACGTGCTGAAGGAGATCCTGCAGGAATACCT
AGAGATTAGCAGCCTGGTGCAGGATGAGGTGATGGCCATTCACCGGGAGATGGCCACAGCTGCG
GCCCGCATCCAACCTGAGGCCGAGTACCAGGGTTTCCTGCGACAGTATGGCTCCGTCCCAGATG
TCCCGCCCTGCGTCACCTTCGATGAGTCGCTGCTTGAGGAGGGTGAGCAGCTGGAGCCTGGGGA
GCTGCAGCTGAACGAGCTGACCGTGGAGAGCGTGCAGCACACGCTCACTTCAGTGACGGATGAC
CTGGCAGTGGCCACCGAGACCATGCTAAGCCGGCAGGAGGCAGTCAACCAGCTGCAGCGAGAGC
TCCGGAGTGAGGAGCAGAGCACCCACCCCCGGGAGCGGGTGCAGCTACTGGGCAAGAGGCAGGC
GCTACACGAGGCACTGCAGGGGCTGCAGGTCGCACTGTGCAGCCAGGCCAAGCTGCAGGCCCAG
CAGGAGCTGCTACAGACCAAGCTGGAGCAGCTGGGCCCCGGCGAGCCCCCAGCTGTGCTGCTCC
TGCAGGACGATCGCCACTCCACCTCGTCCTCGGAGCAGGAGCGAGAGGGGGGAAGGACGCCCAC
GCTGGAGATCATCAAGAGCCACATCTCGGGAATCTTCCGCCCCAAGTTCTCGCTCCCCCCACCG
CTGCAGCTGGTTCCTGAGGTGCAGAAGCCCCTGCATGAGCAGCTGTGGTACCACGGGGCCATCC
CGCGGGCGGAGGTGGCCGAGCTGCTTACGAACTCCGGGGACTTCCTTGTGCGGGAGAGCCAGGG
CAAGCAGGAGTATGTGCTGTCCGTGCTGTGGGACGGCCTGCCACGCCACTTTATCATCCAGTCC
TCCGACAACCTATACCGCCTGGAAGGTGATGGCTTCCCCAGCATCCCCTTGCTCATTGACCACC
TGCTCTGCTCCCAGCAGCCTCTCACCAAGAAGAGCGGTGTTGTTCTGTATAGGGCAGTCCCCAA
GGACAAGTGGGTGCTGAACCACGAGGACTTGGTGTTGGGCGAGCAGATTGGGAGGGGCAACTTT
GGCGAAGTGTTCAGTGGGCGTCTGCGAGCCGACAACACGCCAGTGGCAGTGAAGTCTTGTCGGG
AGACGCTCCCGCCTGACCTCAAGGCCAAGTTCCTGCAAGAAGCCAGGATCCTGAAGCAGTACAG
CCACCCCAACATCGTGCGGCTCATCGGGGTCTGCACGCAGAAGCAGCCCATCTACATCGTCATG
GAGCTGGTGCAGGGGGGCGACTTCCTGACCTTCCTGCGGACCGAGGGAGCCCGCCTTCGCATGA
AGACACTGCTGCAGATGGTGGGGGACGCGGCCGCGGGTATGGAGTACTTGGAGAGCAAGTGCTG
CATCCACAGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTTTTGAAGATCAGT
GACTTTGGGATGTCCCGGGAGGAGGCCGATGGGGTCTACGCAGCCTCAGGGGGCCTCAGACAAG
TCCCCGTGAAGTGGACTGCCCCTGAGGCCCTTAACTACGGCCGCTACTCCTCGGAGAGCGATGT
GTGGAGCTTTGGCATCTTGCTTTGGGAGACCTTCAGCCTGGGGGCCTCGCCCTACCCCAACCTC
AGCAACCAGCAGACACGGGAGTTCGTGGAGAAGGGGGGTCGCCTGCCCTGCCCGGAGCTGTGTC
CTGACGCGGTGTTCCGGCTCATGGAGCAGTGCTGGGCCTACGAACCTGTGCAGCGGCCCAGCTT
CAGCACCATCTCTCAGGAGCTGCAGAGTATCCGGAAGCGGCATCGGTGAGGCTGGGGTCGCTGC
AGGCCGCAGTGTACCTCCTCCTCTGCAGCGCCCACCCTCACCAAGGGACAGCAGCCTGCCATCC
TGGGATCCTGCCCCCAGCACCCCTGCTGCTGCAGGGACAGCCCCAGGTCCGTTCTGGACTCTGC
TCCTGCCGGGTGTCCTTCCTTGGACAGAAACAATAAAACCACTTGTGCCCATCA

hide sequence

RefSeq Acc Id:

XM_013512503 ⟹ XP_013367957

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955416	14,948,121 - 14,959,035 (+)	NCBI

Sequence:

show sequence

ATAGAGCTGGCGCCGGAGCTCTCCTTGGGGAATCCAGCGGGTGGGGAGGGCCAGGACTAGCTTC
CCCAGTCCCTCTCTGGGCGCTGAGACCCTGCCTTCACAGCCTTCAGACAAGTTGGCTGCCCTGA
GCCAGACCCCTGCGCCCACCCCGCCCACCTCAGGCCCCGTCCGCAGGGTCCCGGACTCGCTGGC
CTGGGGAGTGAGGGCCTGCCCCACAGGCCTCTCCCCTCCGCTCTCGGCCATTCCCCCTCAGCCT
CCTCCTCCCTTCCGTTTCCGAGGGAGGGAGGCTGCCGTGGCCCAGCGTGGGGCCGGGGGCCGGT
GGGGCTCGCCCGCCCCTTCCCCTCGGCCCGCCCCGCCTGGGCCAACTGAAACCGCGGGAGGAGG
AAGCACCCAACCAGGAACTGGCCGGGGTTGGCGCGGGCCCGAGTAGGTCCACAGCCACCCAGGA
GCAGGAGCAGCTGCTTGCAAGGCCGCTGAAGCTGCCTCACCCCAGTGACGGCCTCTTTACTGTC
CCCAGAACGCCAGCATGGGCTTCTCCTCGGAGCTGTGCAGCCCCCAGGGCCACGGGGCAGTGCA
GCAGATGCAGGAAGCTGAGCTTCGCTTGCTGGAGGGCATGAGGAAATGGATGGCCCAGCGGGTC
AAGAGCGACCGGGAATATGCGGGGCTGCTCCACCACATGTCCCTGCAGGACGCCGGGGGCCAGA
GCCGGAACAGCGGCCTGGATAGCCCCATCAGCCAGTCCTGGGCTGAGATCACCAGCCAGACCGA
GGGACTGAGCCGAGTGCTGCGGCAGCACGCGGAAGACCTGAACTCAGGGCCGCTGAGCAAGCTG
AGCCTGCTGATCCGGGAGCGGCAGCAGCTGCGTAAGACCTACAGCGAGCAGTGGCAGCAACTGC
AGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGTTGAAGAGCCAGTACCGAGCCCT
GGCCCGGGACAGCACCCAAGCCAGACGCAAGTACCAGGAGGCCAGCAAAGACAAGGACCGGGAC
AAGGCCAAGGACAAGTACGTGCGCAGCCTGTGGAAGCTCTTTGCCCACCACAACCGCTATGTGC
TGGGCGTGCGGGCTGCACAGCTGCACCACCAGCACCACCACCAGCTCATGCTGCCCAGCTTGCT
GCAGTCCCTGCAGGACCTGCACGAGGAGATGGCACACGTGCTGAAGGAGATCCTGCAGGAATAC
CTAGAGATTAGCAGCCTGGTGCAGGATGAGGTGATGGCCATTCACCGGGAGATGGCCACAGCTG
CGGCCCGCATCCAACCTGAGGCCGAGTACCAGGGTTTCCTGCGACAGTATGGCTCCGTCCCAGA
TGTCCCGCCCTGCGTCACCTTCGATGAGTCGCTGCTTGAGGAGGGACACATACGAGCTGCGGCT
CTAACAAGGCCCTGCCCCGGCTGCAGGCTCACTTCAGTGACGGATGACCTGGCAGTGGCCACCG
AGACCATGCTAAGCCGGCAGGAGGCAGTCAACCAGCTGCAGCGAGAGCTCCGGAGTGAGGAGCA
GAGCACCCACCCCCGGGAGCGGGTGCAGCTACTGGGCAAGAGGCAGGCGCTACACGAGGCACTG
CAGGGGCTGCAGGTCGCACTGTGCAGCCAGGCCAAGCTGCAGGCCCAGCAGGAGCTGCTACAGA
CCAAGCTGGAGCAGCTGGGCCCCGGCGAGCCCCCAGCTGTGCTGCTCCTGCAGGACGATCGCCA
CTCCACCTCGTCCTCGGAGCAGGAGCGAGAGGGGGGAAGGACGCCCACGCTGGAGATCATCAAG
AGCCACATCTCGGGAATCTTCCGCCCCAAGTTCTCGCTCCCCCCACCGCTGCAGCTGGTTCCTG
AGGTGCAGAAGCCCCTGCATGAGCAGCTGTGGTACCACGGGGCCATCCCGCGGGCGGAGGTGGC
CGAGCTGCTTACGAACTCCGGGGACTTCCTTGTGCGGGAGAGCCAGGGCAAGCAGGAGTATGTG
CTGTCCGTGCTGTGGGACGGCCTGCCACGCCACTTTATCATCCAGTCCTCCGACAACCTATACC
GCCTGGAAGGTGATGGCTTCCCCAGCATCCCCTTGCTCATTGACCACCTGCTCTGCTCCCAGCA
GCCTCTCACCAAGAAGAGCGGTGTTGTTCTGTATAGGGCAGTCCCCAAGGACAAGTGGGTGCTG
AACCACGAGGACTTGGTGTTGGGCGAGCAGATTGGGAGGGGCAACTTTGGCGAAGTGTTCAGTG
GGCGTCTGCGAGCCGACAACACGCCAGTGGCAGTGAAGTCTTGTCGGGAGACGCTCCCGCCTGA
CCTCAAGGCCAAGTTCCTGCAAGAAGCCAGGATCCTGAAGCAGTACAGCCACCCCAACATCGTG
CGGCTCATCGGGGTCTGCACGCAGAAGCAGCCCATCTACATCGTCATGGAGCTGGTGCAGGGGG
GCGACTTCCTGACCTTCCTGCGGACCGAGGGAGCCCGCCTTCGCATGAAGACACTGCTGCAGAT
GGTGGGGGACGCGGCCGCGGGTATGGAGTACTTGGAGAGCAAGTGCTGCATCCACAGGGACCTG
GCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTTTTGAAGATCAGTGACTTTGGGATGTCCC
GGGAGGAGGCCGATGGGGTCTACGCAGCCTCAGGGGGCCTCAGACAAGTCCCCGTGAAGTGGAC
TGCCCCTGAGGCCCTTAACTACGGCCGCTACTCCTCGGAGAGCGATGTGTGGAGCTTTGGCATC
TTGCTTTGGGAGACCTTCAGCCTGGGGGCCTCGCCCTACCCCAACCTCAGCAACCAGCAGACAC
GGGAGTTCGTGGAGAAGGGGGGTCGCCTGCCCTGCCCGGAGCTGTGTCCTGACGCGGTGTTCCG
GCTCATGGAGCAGTGCTGGGCCTACGAACCTGTGCAGCGGCCCAGCTTCAGCACCATCTCTCAG
GAGCTGCAGAGTATCCGGAAGCGGCATCGGTGAGGCTGGGGTCGCTGCAGGCCGCAGTGTACCT
CCTCCTCTGCAGCGCCCACCCTCACCAAGGGACAGCAGCCTGCCATCCTGGGATCCTGCCCCCA
GCACCCCTGCTGCTGCAGGGACAGCCCCAGGTCCGTTCTGGACTCTGCTCCTGCCGGGTGTCCT
TCCTTGGACAGAAACAATAAAACCACTTGTGCCCATCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005381566	(Get FASTA)	NCBI Sequence Viewer
	XP_005381567	(Get FASTA)	NCBI Sequence Viewer
	XP_013367957	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000013608
	ENSCLAP00000013608.1

RefSeq Acc Id:	XP_005381567 ⟸ XM_005381510
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VCL6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDAGGQSRNSG LDSPISQSWAEITSQTEGLSRVLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELT KTHSQDIEKLKSQYRALARDSTQARRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRA AQLHHQHHHQLMLPSLLQSLQDLHEEMAHVLKEILQEYLEISSLVQDEVMAIHREMATAAARIQ PEAEYQGFLRQYGSVPDVPPCVTFDESLLEEGEQLEPGELQLNELTVESVQHTLTSVTDDLAVA TETMLSRQEAVNQLQRELRSEEQSTHPRERVQLLGKRQALHEALQGLQVALCSQAKLQAQQELL QTKLEQLGPGEPPAVLLLQDDRHSTSSSEQEREGGRTPTLEIIKSHISGIFRPKFSLPPPLQLV PEVQKPLHEQLWYHGAIPRAEVAELLTNSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSSDNL YRLEGDGFPSIPLLIDHLLCSQQPLTKKSGVVLYRAVPKDKWVLNHEDLVLGEQIGRGNFGEVF SGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQ GGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGM SREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQ TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPVQRPSFSTISQELQSIRKRHR hide sequence

RefSeq Acc Id:	XP_005381566 ⟸ XM_005381509
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VCL6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDAGGQSRNSG LDSPISQSWAEITSQTEGLSRVLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELT KTHSQDIEKLKSQYRALARDSTQARRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRA AQLHHQHHHQLMLPSLLQSLQDLHEEMAHVLKEILQEYLEISSLVQDEVMAIHREMATAAARIQ PEAEYQGFLRQYGSVPDVPPCVTFDESLLEEGEQLEPGELQLNELTVESVQHTLTSVTDDLAVA TETMLSRQEAVNQLQRELRSEEQSTHPRERVQLLGKRQALHEALQGLQVALCSQAKLQAQQELL QTKLEQLGPGEPPAVLLLQDDRHSTSSSEQEREGGRTPTLEIIKSHISGIFRPKFSLPPPLQLV PEVQKPLHEQLWYHGAIPRAEVAELLTNSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSSDNL YRLEGDGFPSIPLLIDHLLCSQQPLTKKSGVVLYRAVPKDKWVLNHEDLVLGEQIGRGNFGEVF SGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQ GGDFLTFLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGM SREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQ TREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPVQRPSFSTISQELQSIRKRHR hide sequence

RefSeq Acc Id:

XP_013367957 ⟸ XM_013512503

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDAGGQSRNSG
LDSPISQSWAEITSQTEGLSRVLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELT
KTHSQDIEKLKSQYRALARDSTQARRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRA
AQLHHQHHHQLMLPSLLQSLQDLHEEMAHVLKEILQEYLEISSLVQDEVMAIHREMATAAARIQ
PEAEYQGFLRQYGSVPDVPPCVTFDESLLEEGHIRAAALTRPCPGCRLTSVTDDLAVATETMLS
RQEAVNQLQRELRSEEQSTHPRERVQLLGKRQALHEALQGLQVALCSQAKLQAQQELLQTKLEQ
LGPGEPPAVLLLQDDRHSTSSSEQEREGGRTPTLEIIKSHISGIFRPKFSLPPPLQLVPEVQKP
LHEQLWYHGAIPRAEVAELLTNSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSSDNLYRLEGD
GFPSIPLLIDHLLCSQQPLTKKSGVVLYRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRA
DNTPVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLT
FLRTEGARLRMKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEAD
GVYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVE
KGGRLPCPELCPDAVFRLMEQCWAYEPVQRPSFSTISQELQSIRKRHR

hide sequence

RefSeq Acc Id:

ENSCLAP00000013608 ⟸ ENSCLAT00000013763

Protein Domains

F-BAR Protein kinase SH2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009402	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013763	ENTREZGENE
	ENSCLAT00000013763.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1270.60	UniProtKB/TrEMBL
	3.30.505.10	UniProtKB/TrEMBL
	HR1 repeat	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	AH/BAR_dom_sf	UniProtKB/TrEMBL
	F_BAR	UniProtKB/TrEMBL
	FCH_dom	UniProtKB/TrEMBL
	Fes/Fps/Fer_SH2	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	Tyr-prot_kinase_Fes/Fps	UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/TrEMBL
	Tyr_kinase_cat_dom	UniProtKB/TrEMBL
NCBI Gene	Fes	ENTREZGENE
PANTHER	TYROSINE-PROTEIN KINASE	UniProtKB/TrEMBL
	TYROSINE-PROTEIN KINASE FES/FPS	UniProtKB/TrEMBL
Pfam	FCH	UniProtKB/TrEMBL
	PK_Tyr_Ser-Thr	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
PIRSF	TyrPK_fps	UniProtKB/TrEMBL
PRINTS	TYRKINASE	UniProtKB/TrEMBL
PROSITE	F_BAR	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
SMART	FCH	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	TyrKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103657	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A8C2VCL6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Fes	FES proto-oncogene, tyrosine kinase		feline sarcoma oncogene	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)