Adgra2 (adhesion G protein-coupled receptor A2) - Rat Genome Database

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Gene: Adgra2 (adhesion G protein-coupled receptor A2) Chinchilla lanigera
Analyze
Symbol: Adgra2
Name: adhesion G protein-coupled receptor A2
RGD ID: 8872834
Description: INVOLVED IN angiogenesis (ortholog); canonical Wnt signaling pathway (ortholog); central nervous system development (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia 54 (ortholog); high grade glioma (ortholog); FOUND IN cell surface (ortholog); intracellular membrane-bounded organelle (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G protein-coupled receptor 124; G-protein coupled receptor 124; Gpr124
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546313,514,082 - 13,548,339 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546313,514,065 - 13,549,806 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Adgra2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546313,514,082 - 13,548,339 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546313,514,065 - 13,549,806 (+)NCBIChiLan1.0ChiLan1.0
ADGRA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38837,796,883 - 37,844,896 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl837,784,191 - 37,844,896 (+)EnsemblGRCh38hg38GRCh38
GRCh37837,654,401 - 37,702,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36837,773,932 - 37,820,650 (+)NCBINCBI36Build 36hg18NCBI36
Build 34837,773,931 - 37,820,650NCBI
Celera836,605,963 - 36,653,084 (+)NCBICelera
Cytogenetic Map8p11.23NCBI
HuRef836,189,286 - 36,236,033 (+)NCBIHuRef
CHM1_1837,855,880 - 37,902,951 (+)NCBICHM1_1
T2T-CHM13v2.0838,073,278 - 38,121,297 (+)NCBIT2T-CHM13v2.0
Adgra2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39827,575,546 - 27,613,464 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl827,575,611 - 27,613,464 (+)EnsemblGRCm39 Ensembl
GRCm38827,085,520 - 27,123,436 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl827,085,583 - 27,123,436 (+)EnsemblGRCm38mm10GRCm38
MGSCv37828,196,313 - 28,233,894 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36828,551,777 - 28,589,358 (+)NCBIMGSCv36mm8
Celera828,575,397 - 28,613,080 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map815.91NCBI
Adgra2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81671,635,814 - 71,674,275 (-)NCBIGRCr8
mRatBN7.21664,932,964 - 64,971,433 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1664,933,315 - 64,971,483 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01669,094,587 - 69,133,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1669,095,936 - 69,132,584 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,768,542 - 68,806,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,255,045 - 69,293,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1662,852,507 - 62,890,663 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
ADGRA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2756,359,053 - 56,404,976 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1832,076,102 - 32,121,377 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0837,098,486 - 37,144,437 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1834,275,651 - 34,321,836 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl834,276,267 - 34,321,836 (+)Ensemblpanpan1.1panPan2
ADGRA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11627,547,722 - 27,583,069 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1627,549,308 - 27,583,070 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1628,066,037 - 28,099,848 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01629,448,402 - 29,482,344 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1629,446,278 - 29,483,197 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11627,668,324 - 27,703,792 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01628,245,885 - 28,281,475 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01628,285,068 - 28,320,567 (-)NCBIUU_Cfam_GSD_1.0
Adgra2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494350,164,990 - 50,203,129 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367101,257,931 - 1,298,885 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367101,258,088 - 1,296,346 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1548,573,197 - 48,610,668 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11548,572,953 - 48,611,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,689,430 - 55,727,513 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1835,834,840 - 35,879,851 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl835,834,876 - 35,878,233 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660526,124,512 - 6,170,638 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adgra2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247805,752,846 - 5,793,846 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247805,757,535 - 5,793,794 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000003842   ⟹   ENSCLAP00000003766
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546313,514,082 - 13,548,339 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000003843   ⟹   ENSCLAP00000003767
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546313,514,082 - 13,548,339 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000003844   ⟹   ENSCLAP00000003768
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546313,544,559 - 13,547,360 (+)Ensembl
RefSeq Acc Id: XM_005398475   ⟹   XP_005398532
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546313,514,065 - 13,549,806 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398532 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003766
  ENSCLAP00000003766.1
  ENSCLAP00000003767.1
  ENSCLAP00000003768.1
Reference Protein Sequences
RefSeq Acc Id: XP_005398532   ⟸   XM_005398475
- UniProtKB: A0A8C2YJR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000003767   ⟸   ENSCLAT00000003843
RefSeq Acc Id: ENSCLAP00000003768   ⟸   ENSCLAT00000003844
RefSeq Acc Id: ENSCLAP00000003766   ⟸   ENSCLAT00000003842
Protein Domains
G-protein coupled receptors family 2 profile   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002684 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003842 ENTREZGENE
  ENSCLAT00000003842.1 UniProtKB/TrEMBL
  ENSCLAT00000003843.1 UniProtKB/TrEMBL
  ENSCLAT00000003844.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.220.50 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  4.10.1240.10 UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPCR_2_secretin-like_CS UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Gpr124 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR A2 UniProtKB/TrEMBL
  G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF111418 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A8C2UQM9_CHILA UniProtKB/TrEMBL
  A0A8C2YJR2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YJR8_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Adgra2  adhesion G protein-coupled receptor A2  Gpr124  G protein-coupled receptor 124  Symbol and/or name change 5135510 APPROVED