Scrib (scribble planar cell polarity protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Scrib (scribble planar cell polarity protein) Chinchilla lanigera
Analyze
Symbol: Scrib
Name: scribble planar cell polarity protein
RGD ID: 8871697
Description: ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN apoptotic process involved in morphogenesis (ortholog); astrocyte cell migration (ortholog); auditory receptor cell morphogenesis (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); genetic disease (ortholog); FOUND IN adherens junction (ortholog); basolateral plasma membrane (ortholog); cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,461,760 - 2,482,098 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,461,526 - 2,482,734 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scrib
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,461,760 - 2,482,098 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,461,526 - 2,482,734 (-)NCBIChiLan1.0ChiLan1.0
SCRIB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,790,925 - 143,815,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,790,920 - 143,815,773 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,873,095 - 144,897,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,945,078 - 144,969,537 (-)NCBINCBI36Build 36hg18NCBI36
Celera8141,185,992 - 141,210,452 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,126,075 - 140,150,540 (-)NCBIHuRef
CHM1_18144,913,332 - 144,937,791 (-)NCBICHM1_1
T2T-CHM13v2.08144,947,418 - 144,972,471 (-)NCBIT2T-CHM13v2.0
Scrib
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,919,011 - 75,941,633 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,919,007 - 75,941,633 (-)EnsemblGRCm39 Ensembl
GRCm381576,047,162 - 76,069,784 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,047,158 - 76,069,784 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,877,616 - 75,900,160 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,874,441 - 75,896,985 (-)NCBIMGSCv36mm8
Celera1577,548,113 - 77,570,657 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.29NCBI
Scrib
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,640,034 - 109,663,354 (-)NCBIGRCr8
mRatBN7.27107,759,343 - 107,782,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,759,343 - 107,782,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,499,717 - 109,522,737 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,723,394 - 111,746,414 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,680,128 - 111,703,152 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,105,810 - 117,128,802 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,105,810 - 117,128,798 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,091,481 - 117,114,469 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,077,733 - 114,100,721 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7104,116,077 - 104,138,929 (-)NCBICelera
Cytogenetic Map7q34NCBI
SCRIB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,275,637 - 161,301,755 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,792,596 - 136,819,011 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,544,797 - 140,571,078 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,557,479 - 143,582,409 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,557,722 - 143,582,353 (-)Ensemblpanpan1.1panPan2
SCRIB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,356,405 - 37,374,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,356,405 - 37,374,681 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,312,750 - 37,331,086 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,828,183 - 37,846,535 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,828,186 - 37,846,509 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,502,286 - 37,520,617 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,619,233 - 37,637,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,100,565 - 38,118,912 (-)NCBIUU_Cfam_GSD_1.0
Scrib
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303923,076 - 943,996 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,349,188 - 8,369,864 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,349,175 - 8,370,099 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCRIB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4825,062 - 852,664 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14824,925 - 852,360 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SCRIB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,008,722 - 138,033,874 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,008,579 - 138,033,843 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,843,884 - 1,869,060 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scrib
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,997,408 - 13,018,533 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,997,358 - 13,018,765 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000015882   ⟹   ENSCLAP00000015719
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554542,461,760 - 2,482,098 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015883   ⟹   ENSCLAP00000015720
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554542,461,760 - 2,482,098 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015884   ⟹   ENSCLAP00000015721
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554542,461,760 - 2,482,098 (-)Ensembl
RefSeq Acc Id: XM_013520053   ⟹   XP_013375507
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554542,461,526 - 2,482,734 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013375507 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015719
  ENSCLAP00000015719.1
  ENSCLAP00000015720.1
  ENSCLAP00000015721.1
Reference Protein Sequences
RefSeq Acc Id: XP_013375507   ⟸   XM_013520053
- UniProtKB: A0A8C2VHK3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015720   ⟸   ENSCLAT00000015883
RefSeq Acc Id: ENSCLAP00000015719   ⟸   ENSCLAT00000015882
RefSeq Acc Id: ENSCLAP00000015721   ⟸   ENSCLAT00000015884
Protein Domains
PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010805 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015882 ENTREZGENE
  ENSCLAT00000015882.1 UniProtKB/TrEMBL
  ENSCLAT00000015883.1 UniProtKB/TrEMBL
  ENSCLAT00000015884.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene Scrib ENTREZGENE
PANTHER DISCS LARGE UniProtKB/TrEMBL
  PROTEIN SCRIBBLE HOMOLOG UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A8C2VHG4_CHILA UniProtKB/TrEMBL
  A0A8C2VHK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YQF9_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 Scrib  scribble planar cell polarity protein    scribbled planar cell polarity protein  Symbol and/or name change 5135510 APPROVED