Mrtfb (myocardin related transcription factor B) - Rat Genome Database

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Gene: Mrtfb (myocardin related transcription factor B) Chinchilla lanigera
Analyze
Symbol: Mrtfb
Name: myocardin related transcription factor B
RGD ID: 8867356
Description: ENCODES a protein that exhibits actin binding (ortholog); DNA-binding transcription factor activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); blood vessel morphogenesis (ortholog); cardiac muscle tissue development (ortholog); ASSOCIATED WITH pervasive developmental disorder (ortholog); xeroderma pigmentosum group F (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MKL/myocardin-like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; Mkl2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,547,829 - 4,733,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,542,700 - 4,733,646 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Mrtfb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,547,829 - 4,733,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,542,700 - 4,733,646 (-)NCBIChiLan1.0ChiLan1.0
MRTFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381613,994,774 - 14,266,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1614,071,319 - 14,266,773 (+)EnsemblGRCh38hg38GRCh38
GRCh371614,164,919 - 14,360,636 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,072,697 - 14,268,131 (+)NCBINCBI36hg18NCBI36
Build 341614,072,696 - 14,268,130NCBI
Celera1614,340,460 - 14,536,766 (+)NCBI
Cytogenetic Map16p13.12NCBI
HuRef1614,082,327 - 14,277,730 (+)NCBIHuRef
CHM1_11614,165,144 - 14,360,614 (+)NCBICHM1_1
T2T-CHM13v2.01614,108,323 - 14,304,042 (+)NCBI
Mrtfb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,073,913 - 13,235,393 (+)NCBIGRCm39mm39
GRCm39 Ensembl1613,074,345 - 13,235,393 (+)Ensembl
GRCm381613,256,056 - 13,417,529 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,256,481 - 13,417,529 (+)EnsemblGRCm38mm10GRCm38
MGSCv371613,256,574 - 13,417,622 (+)NCBIGRCm37mm9NCBIm37
MGSCv361613,272,217 - 13,326,281 (+)NCBImm8
Celera1613,859,728 - 14,019,765 (+)NCBICelera
Cytogenetic Map16A1NCBI
Mrtfb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2101,116,315 - 1,278,106 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl101,116,310 - 1,277,897 (+)Ensembl
Rnor_6.0101,151,163 - 1,273,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01011,829,918 - 11,951,270 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10180,081 - 341,402 (+)NCBICelera
Cytogenetic Map10q11NCBI
MRTFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11614,427,091 - 14,619,198 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1614,493,351 - 14,613,860 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01612,999,165 - 13,195,012 (+)NCBIMhudiblu_PPA_v0panPan3
MRTFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,902,749 - 29,113,448 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,918,350 - 29,098,220 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha630,265,501 - 30,476,132 (-)NCBI
ROS_Cfam_1.0629,066,342 - 29,277,006 (-)NCBI
ROS_Cfam_1.0 Ensembl629,077,199 - 29,271,056 (-)Ensembl
UMICH_Zoey_3.1628,868,907 - 29,079,923 (-)NCBI
UNSW_CanFamBas_1.0628,756,781 - 28,967,376 (-)NCBI
UU_Cfam_GSD_1.0629,174,173 - 29,385,094 (-)NCBI
Mrtfb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344114,317,026 - 114,480,361 (+)NCBI
SpeTri2.0NW_0049365012,414,696 - 2,571,627 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRTFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,968,215 - 29,167,637 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,964,758 - 29,240,125 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MRTFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1513,530,313 - 13,725,359 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl513,609,016 - 13,720,022 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606816,331,363 - 16,528,431 (-)NCBIVero_WHO_p1.0
Mrtfb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247824,217,522 - 4,408,175 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247824,217,620 - 4,416,161 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018058   ⟹   ENSCLAP00000017880
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554424,547,829 - 4,733,724 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000018059   ⟹   ENSCLAP00000017881
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554424,547,829 - 4,617,051 (-)Ensembl
RefSeq Acc Id: XM_013517824   ⟹   XP_013373278
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554424,542,700 - 4,733,646 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013373278 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013373278   ⟸   XM_013517824
- Sequence:
RefSeq Acc Id: ENSCLAP00000017880   ⟸   ENSCLAT00000018058
RefSeq Acc Id: ENSCLAP00000017881   ⟸   ENSCLAT00000018059
Protein Domains
SAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012268 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000017880 ENTREZGENE
  ENSCLAP00000017880.1 UniProtKB/TrEMBL
  ENSCLAP00000017881.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018058 ENTREZGENE
  ENSCLAT00000018058.1 UniProtKB/TrEMBL
  ENSCLAT00000018059.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/TrEMBL
InterPro Myocardin-like UniProtKB/TrEMBL
  RPEL_repeat UniProtKB/TrEMBL
  SAP_dom UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/TrEMBL
NCBI Gene Mkl2 ENTREZGENE
PANTHER PTHR22793 UniProtKB/TrEMBL
Pfam RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
PROSITE RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
SMART RPEL UniProtKB/TrEMBL
  SAP UniProtKB/TrEMBL
Superfamily-SCOP SSF68906 UniProtKB/TrEMBL
UniProt A0A8C2VMI5_CHILA UniProtKB/TrEMBL
  A0A8C2VSY3_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-19 Mrtfb  myocardin related transcription factor B  Mkl2  MKL1/myocardin like 2  Symbol and/or name change 5135510 APPROVED
2016-08-03 Mkl2  MKL1/myocardin like 2    MKL/myocardin-like 2  Symbol and/or name change 5135510 APPROVED