Mtmr8 (myotubularin related protein 8)

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Gene: Mtmr8 (myotubularin related protein 8) Chinchilla lanigera

Analyze

Symbol:

Mtmr8

Name:

myotubularin related protein 8

RGD ID:

8866716

Description:

ENCODES a protein that exhibits phosphatidylinositol-3,5-bisphosphate phosphatase activity (ortholog); phosphatidylinositol-3-phosphatase activity (ortholog); INVOLVED IN negative regulation of autophagy (ortholog); phosphatidylinositol dephosphorylation (ortholog); regulation of macroautophagy (ortholog); ASSOCIATED WITH autistic disorder (ortholog); osteopathia striata with cranial sclerosis (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN cytoplasm (ortholog); nuclear envelope (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955475	4,358,264 - 4,391,349 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

osteopathia striata with cranial sclerosis (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of autophagy (ISO)

phosphatidylinositol dephosphorylation (ISO)

regulation of macroautophagy (ISO)

Cellular Component

cytoplasm (ISO)

nuclear envelope (ISO)

protein-containing complex (ISO)

Molecular Function

phosphatidylinositol-3,5-bisphosphate phosphatase activity (ISO)

phosphatidylinositol-3-phosphatase activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data

Mtmr8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955475	4,358,264 - 4,391,349 (+)	NCBI	ChiLan1.0	ChiLan1.0

MTMR8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	64,268,081 - 64,395,452 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	X	64,268,081 - 64,395,452 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	63,487,961 - 63,615,332 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	63,404,686 - 63,532,036 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	X	63,270,982 - 63,398,332	NCBI
Celera	X	63,834,792 - 63,962,167 (-)	NCBI
Cytogenetic Map	X	q11.2	NCBI
HuRef	X	57,310,906 - 57,438,037 (-)	NCBI		HuRef
CHM1_1	X	63,380,423 - 63,508,025 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	62,693,357 - 62,820,731 (-)	NCBI

MTMR8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	X	63,469,888 - 63,597,137 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	63,473,727 - 63,597,332 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	X	53,388,164 - 53,515,593 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

Mtmr8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	52,570,573 - 52,655,524 (+)	NCBI
SpeTri2.0	NW_004936635	3,336,218 - 3,415,998 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTMR8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	50,935,136 - 51,077,766 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	50,931,199 - 51,077,796 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	43,482,857 - 43,621,125 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTMR8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	54,656,054 - 54,765,846 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	X	54,656,506 - 54,731,548 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666083	1,909,485 - 2,027,914 (-)	NCBI	Vero_WHO_p1.0

Mtmr8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624898	2,528,422 - 2,630,274 (+)	NCBI	HetGla_female_1.0		hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013502805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01054873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01054874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01054875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_013502805 ⟹ XP_013358259

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955475	4,358,264 - 4,391,349 (+)	NCBI

Sequence:

show sequence

ATGTCAACAGGCCATGAAAAGGCCCCAGAGGATAGGAAGTCAGAGGACACATCAGCAGGTTACA
AAGGACACATCAGCAAGATGTTTTCTGACAAAGATAAACAATTTGACAAATGGTCTTCAGTCAT
GTCCCCTTATCTGCCACTAGGTGGGAGTGCAATGAAGGTAAAAAAAGTCAATGTCTTGCTTCAG
TGTTCTGATGGATGAGACCACACAGCACAAGTCTGCTCAGTGGCTAGCATCCTCCTAGGTCCAT
TTTATACGACATTCAATGGACTCATGATCCTAATAGAGAACAAATGGATATCTATGGGTCACAA
GTTCTCCAAGAACTGTGGGCACCTAGATGGGGACTCTAAAAATGTCTCCCCTATCTTCATTCCA
TTCCTAGATTGTATTTGGCTACTAATGGAATACTTTCCCTGTGCCTTTGAGTTTAATGAAGACT
TCTTGATGGAGATCCATGATCATGTTTTTCCTTGCCAGTTTGGAAGTTTTCTTGGAAACTGTCA
GAAGTATTGGGAAGACCTAAGGAAGCTGCAAGCTTATGATGAGCCATCAGAATAGGTCTGTACC
TGCTCTCAGTTGGAGAATTTATTACTCAAGTATCTGGGAAGGGCTTTGATCAATCCTCTTGGCT
TTATTGGTATTGATGGAGACTTAAATACCTTGATGAAGAATGGAACCATTTCCAGGGAAGGCCT
CTGAGCTCAGGTGGATCAAGCAGAAAGCCAGTGTATAGACCTTTACCATAACTGCTGTAGGATC
ATGAGCAGCTTAAAGGCCATAAATATATCTGGGTATTTGGACATCTCTGGAGCCATGGCCATCT
CTGGAGATGCAGATATCTTTAGGGCCATTGACTTTTGTGAAGATAAAGGCATTTTTGGAGCTAT
GGGTTTCTCTGAAGATTTGAATATCTCTGATGTCACTAGTACTCTTGGAAACATGGATACTTTT
GAGGCCAAGTGCTTCTTTAGAAATATTGGCATCTCCAGAGGCACAGGCTTCTCTGAGACCAGGT
GCTTCTCTGGAAGTATGGATTTCTCTGACAGCATGGGCATCTGA

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Protein Sequences


Protein RefSeqs	XP_013358259	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_013358259 ⟸ XM_013502805

- Sequence:

show sequence

MSTGHEKAPEDRKSEDTSAGYKGHISKMFSDKDKQFDKWSSVMSPYLPLGGSAMKVKKVNVLLQ
CSDGXDHTAQVCSVASILLGPFYTTFNGLMILIENKWISMGHKFSKNCGHLDGDSKNVSPIFIP
FLDCIWLLMEYFPCAFEFNEDFLMEIHDHVFPCQFGSFLGNCQKYWEDLRKLQAYDEPSEXVCT
CSQLENLLLKYLGRALINPLGFIGIDGDLNTLMKNGTISREGLXAQVDQAESQCIDLYHNCCRI
MSSLKAINISGYLDISGAMAISGDADIFRAIDFCEDKGIFGAMGFSEDLNISDVTSTLGNMDTF
EAKCFFRNIGISRGTGFSETRCFSGSMDFSDSMGI

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Mtmr8	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar