Srpx2 (sushi repeat containing protein X-linked 2) - Rat Genome Database

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Gene: Srpx2 (sushi repeat containing protein X-linked 2) Chinchilla lanigera
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Symbol: Srpx2
Name: sushi repeat containing protein X-linked 2
RGD ID: 8864242
Description: ENCODES a protein that exhibits hepatocyte growth factor binding (ortholog); identical protein binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell motility (ortholog); cell-cell adhesion (ortholog); positive regulation of cell migration involved in sprouting angiogenesis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); developmental and epileptic encephalopathy 9 (ortholog); genetic disease (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); excitatory synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sushi repeat containing protein, X-linked 2; sushi repeat-containing protein SRPX2; sushi-repeat containing protein, X-linked 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555036,795,734 - 6,821,119 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555036,795,793 - 6,817,779 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Srpx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555036,795,734 - 6,821,119 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555036,795,793 - 6,817,779 (+)NCBIChiLan1.0ChiLan1.0
SRPX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,644,199 - 100,675,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX100,644,195 - 100,675,788 (+)EnsemblGRCh38hg38GRCh38
GRCh37X99,899,196 - 99,930,785 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,785,819 - 99,812,952 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X99,705,369 - 99,732,435NCBI
CeleraX100,417,899 - 100,445,036 (+)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX89,699,083 - 89,726,241 (+)NCBIHuRef
CHM1_1X99,792,044 - 99,819,192 (+)NCBICHM1_1
T2T-CHM13v2.0X99,086,631 - 99,118,247 (+)NCBIT2T-CHM13v2.0
Srpx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X132,809,155 - 132,833,195 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX132,809,175 - 132,833,195 (+)EnsemblGRCm39 Ensembl
GRCm38X133,908,416 - 133,932,448 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX133,908,426 - 133,932,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X130,442,965 - 130,467,001 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,255,046 - 129,278,164 (+)NCBIMGSCv36mm8
CeleraX116,784,471 - 116,808,449 (+)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX55.47NCBI
Srpx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,399,748 - 101,425,486 (+)NCBIGRCr8
mRatBN7.2X97,106,455 - 97,132,197 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,106,561 - 97,132,195 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX98,780,980 - 98,806,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,290,762 - 102,316,123 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X99,794,158 - 99,819,519 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X104,734,035 - 104,760,658 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX104,734,082 - 104,760,547 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X104,569,972 - 104,594,902 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,446,756 - 121,468,691 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX98,154,669 - 98,178,553 (+)NCBICelera
Cytogenetic MapXq32NCBI
SRPX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,248,125 - 100,279,048 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,253,972 - 100,285,692 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X89,854,389 - 89,886,776 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X99,994,560 - 100,021,241 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX99,994,560 - 100,021,241 (+)Ensemblpanpan1.1panPan2
SRPX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X74,513,473 - 74,536,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX74,513,774 - 74,534,910 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X75,923,141 - 75,944,851 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX75,922,966 - 75,944,592 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X73,485,604 - 73,507,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,155,899 - 75,177,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X74,916,918 - 74,938,615 (+)NCBIUU_Cfam_GSD_1.0
Srpx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,671,204 - 63,697,221 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365845,855,818 - 5,880,259 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365845,855,818 - 5,879,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRPX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,336,744 - 82,363,867 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,336,741 - 82,363,868 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,178,156 - 90,205,276 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRPX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X88,954,310 - 88,982,608 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX88,957,316 - 88,982,305 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606513,884,531 - 13,916,219 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srpx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,944,019 - 1,964,983 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,944,073 - 1,967,106 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000002965   ⟹   ENSCLAP00000002908
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555036,795,734 - 6,821,119 (+)Ensembl
RefSeq Acc Id: XM_005406933   ⟹   XP_005406990
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555036,795,796 - 6,817,779 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005406934   ⟹   XP_005406991
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555036,795,796 - 6,817,779 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013505861   ⟹   XP_013361315
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555036,795,793 - 6,817,779 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005406990 (Get FASTA)   NCBI Sequence Viewer  
  XP_005406991 (Get FASTA)   NCBI Sequence Viewer  
  XP_013361315 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002908
  ENSCLAP00000002908.1
RefSeq Acc Id: XP_005406991   ⟸   XM_005406934
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UT33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005406990   ⟸   XM_005406933
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UT33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013361315   ⟸   XM_013505861
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UT33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002908   ⟸   ENSCLAT00000002965
Protein Domains
HYR   Sushi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002093 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002965 ENTREZGENE
  ENSCLAT00000002965.1 UniProtKB/TrEMBL
Gene3D-CATH Complement Module, domain 1 UniProtKB/TrEMBL
InterPro DUF4174 UniProtKB/TrEMBL
  HYR_dom UniProtKB/TrEMBL
  SRPX-like UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/TrEMBL
NCBI Gene Srpx2 ENTREZGENE
PANTHER PTHR46343 UniProtKB/TrEMBL
  PTHR46343:SF3 UniProtKB/TrEMBL
Pfam DUF4174 UniProtKB/TrEMBL
  HYR UniProtKB/TrEMBL
  Sushi UniProtKB/TrEMBL
PROSITE HYR UniProtKB/TrEMBL
  SUSHI UniProtKB/TrEMBL
SMART CCP UniProtKB/TrEMBL
Superfamily-SCOP SSF57535 UniProtKB/TrEMBL
UniProt A0A8C2UT33 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 Srpx2  sushi repeat containing protein X-linked 2    sushi repeat containing protein, X-linked 2  Symbol and/or name change 5135510 APPROVED
2016-08-03 Srpx2  sushi repeat containing protein, X-linked 2    sushi-repeat containing protein, X-linked 2  Symbol and/or name change 5135510 APPROVED