Polr1c (RNA polymerase I and III subunit C)

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Gene: Polr1c (RNA polymerase I and III subunit C) Chinchilla lanigera

Analyze

Symbol:

Polr1c

Name:

RNA polymerase I and III subunit C

RGD ID:

8863270

Description:

PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase III transcription pathway; ASSOCIATED WITH hypomyelinating leukodystrophy 11 (ortholog); Mandibulofacial Dysostosis (ortholog); Treacher Collins syndrome 3 (ortholog); FOUND IN nucleoplasm (ortholog); RNA polymerase I complex (ortholog); RNA polymerase III complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

DNA-directed RNA polymerases I and III subunit RPAC1; polymerase (RNA) I polypeptide C, 30kDa; RNA polymerase I subunit C

RGD Orthologs

Human

Mouse

Rat

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,346,397 - 9,350,591 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,346,397 - 9,350,591 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypomyelinating leukodystrophy 11 (ISO)

Mandibulofacial Dysostosis (ISO)

Treacher Collins syndrome 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nucleoplasm (ISO)

RNA polymerase I complex (ISO)

RNA polymerase III complex (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase I transcription pathway (ISO)

RNA polymerase III transcription pathway (ISO)

References

References - curated


1.	Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2.	OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data

Polr1c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	9,346,397 - 9,350,591 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	9,346,397 - 9,350,591 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLR1C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	6	43,509,702 - 43,562,419 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	6	43,517,089 - 43,562,407 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	6	43,484,777 - 43,497,114 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	6	43,484,827 - 43,530,144 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	43,592,769 - 43,605,092 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	6	45,036,412 - 45,048,735 (+)	NCBI
Cytogenetic Map	6	p21.1	NCBI
HuRef	6	43,202,730 - 43,208,225 (+)	NCBI		HuRef
CHM1_1	6	43,487,894 - 43,500,246 (+)	NCBI		CHM1_1

Polr1c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	46,554,846 - 46,558,971 (-)	NCBI	GRCm39		mm39
GRCm38	17	46,243,920 - 46,248,045 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	46,243,920 - 46,248,054 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	46,380,869 - 46,384,994 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	17	45,707,509 - 45,711,545 (-)	NCBI			mm8
Celera	17	49,677,058 - 49,681,183 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI

Polr1c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	14,735,740 - 14,739,852 (+)	NCBI
Rnor_6.0 Ensembl	9	17,120,759 - 17,124,871 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	17,120,759 - 17,124,871 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	16,017,436 - 16,021,548 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	10,298,309 - 10,302,421 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	10,295,630 - 10,299,743 (+)	NCBI
Celera	9	12,483,058 - 12,487,170 (+)	NCBI		Celera
Cytogenetic Map	9	q12	NCBI

POLR1C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	6	44,399,936 - 44,404,420 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	44,395,787 - 44,412,257 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	6	43,101,771 - 43,121,460 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

POLR1C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	12	11,978,422 - 12,008,579 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	12	11,978,337 - 11,982,265 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Polr1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936476	16,483,203 - 16,487,360 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR1C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	38,507,073 - 38,537,943 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	38,511,521 - 38,531,938 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	44,092,595 - 44,111,879 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR1C
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	28,637,868 - 28,649,898 (-)	NCBI

Polr1c
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	16,125,322 - 16,129,339 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005389779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01034527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01006305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSCLAT00000013561 ⟹ ENSCLAP00000013408

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955437	9,346,397 - 9,350,591 (+)	Ensembl

RefSeq Acc Id:

XM_005389779 ⟹ XP_005389836

RefSeq Status:

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955437	9,346,397 - 9,350,591 (+)	NCBI

Sequence:

show sequence

TACGAAAGCAGGCTGCTGGGAAAAAAGCGCCGGAGTGAGGACCAGGTCTCGTGGAGTGGTTGAA
GATGGCGGCGTCGCGGGCGGTGGAGGAGATGCGGAACCGCGTGGTTCTGGGGGAGTTCGGGGTT
CGCAACGTTCATACCACGGACTTTCCCGGGAACTATTCGGGTTACGACGATGCCTGGGACCAGG
ACCGCTTCGAGAAGAACTTCCGCGTGGATGTGGTACATATGGATGAAAACTCATTGGAGTTTGA
CATGGTGGGAATTGATGCAGCAATTGCCAACGCTTTCCGGCGAATTCTTTTAGCAGAGGTGCCA
ACAATGGCTGTGGAAAAGGTCCTGGTGTACAACAACACATCCATTGTCCAGGATGAGATCCTTG
CTCACCGTCTGGGGCTCATTCCTATTCTTGCTGATCCTCGGCTTTTTGAATTTCGGAATGAAGG
AGACGAAGAAGGCACAGAGATAGACACTCTGCAGTTCCGGCTGCAGGTCAGGTGCACCCGGAAC
CCCCACGCTGCTAAAGATTCCTCGGACCCCAACGAACTCTATGTGAACCACAAGGTGTACACCA
GGCACATGACATGGGTTCCCCTGGGGAACCAGGCTGATGTTTTCCCAGAGGGCACAATCCGGCC
AGTGCACGATGACATCCTCATTGCCCAGCTGCGGCCTGGCCAGGAGATTGACCTGCTCATGCAC
TGTGTCAAAGGCATTGGCAAAGATCATGCCAAGTTCTCTCCGGTGGCAACAGCCAGTTACAGGC
TTCTGCCAGACATCACCCTGCTTGAACCTGTGGAAGGCGAGGCCGCAGAGGAGCTCAGCCGCTG
TTTCTCACCCGGTGTTATTGAGGTGCAGGAAGTGCAAGGTAAGAAGGTGGCCCGAGTTGCTAAT
CCCAGGCTGGACACCTTCAGCAGGGAGGTCTTCCGGCATGAGAAGCTGAAGAAGGCTGTGCGGC
TTGCCCGTGTCCGGGATCATTACATCTTTTCTGTGGAGTCTACAGGAGTGTTGCCACCAGATGT
GCTGGTGAGCGAAGCCATCAAAGTGCTGATGGGGAAGTGCCAGCGGTTCCTGGATGAACTGGAT
GCTGTGCAGATGGACTGAGGCTGCTGGGGACTCACAGTGGCTGGGATTGGCTGCCTCCGGTGGT
TCCATGGGACTGCTGGACCCATGGGACTGACTAGAGGTCCAATTCCAGTTTGTCAAATCAATAC
ATTTTGTTAAATGTGCCACAGAATGGGACTTTATGCCTTTGTAAGGCCCTTGATGTAAATAAAT
TCATGTCCAAAACTTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005389836	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_005389836 ⟸ XM_005389779

- Sequence:

show sequence

MAASRAVEEMRNRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFD
MVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPILADPRLFEFRNEG
DEEGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHKVYTRHMTWVPLGNQADVFPEGTIRP
VHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRC
FSPGVIEVQEVQGKKVARVANPRLDTFSREVFRHEKLKKAVRLARVRDHYIFSVESTGVLPPDV
LVSEAIKVLMGKCQRFLDELDAVQMD

hide sequence

RefSeq Acc Id:

ENSCLAP00000013408 ⟸ ENSCLAT00000013561

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009266	Ensembl, ENTREZGENE
Ensembl Protein	ENSCLAP00000013408	ENTREZGENE
Ensembl Transcript	ENSCLAT00000013561	ENTREZGENE
NCBI Gene	Polr1c	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-03-13	Polr1c	RNA polymerase I and III subunit C		RNA polymerase I subunit C	Symbol and/or name change	5135510	APPROVED
2016-07-26	Polr1c	RNA polymerase I subunit C		polymerase (RNA) I polypeptide C, 30kDa	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations