Chrm5 (cholinergic receptor muscarinic 5) - Rat Genome Database

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Gene: Chrm5 (cholinergic receptor muscarinic 5) Chinchilla lanigera
Analyze
Symbol: Chrm5
Name: cholinergic receptor muscarinic 5
RGD ID: 8861842
Description: ENCODES a protein that exhibits G protein-coupled acetylcholine receptor activity (ortholog); INVOLVED IN dopamine transport (ortholog); regulation of phosphatidylinositol dephosphorylation (ortholog); transmission of nerve impulse (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; G protein mediated signaling pathway via Galphaq family; ASSOCIATED WITH Bloom syndrome (ortholog); Cocaine-Related Disorders (ortholog); colorectal cancer (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cholinergic receptor, muscarinic 5; muscarinic acetylcholine receptor M5
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955416526,755 - 528,353 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955416526,718 - 528,353 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Chrm5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955416526,755 - 528,353 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955416526,718 - 528,353 (-)NCBIChiLan1.0ChiLan1.0
CHRM5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381533,968,497 - 34,067,458 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1533,968,497 - 34,067,458 (+)EnsemblGRCh38hg38GRCh38
GRCh371534,260,698 - 34,359,659 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361532,097,720 - 32,144,579 (+)NCBINCBI36hg18NCBI36
Build 341532,097,719 - 32,144,579NCBI
Celera1511,064,121 - 11,160,334 (+)NCBI
Cytogenetic Map15q14NCBI
HuRef1511,124,408 - 11,221,244 (+)NCBIHuRef
CHM1_11534,379,045 - 34,475,247 (+)NCBICHM1_1
T2T-CHM13v2.01531,766,653 - 31,865,649 (+)NCBI
Chrm5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392112,309,078 - 112,365,491 (-)NCBIGRCm39mm39
GRCm39 Ensembl2112,309,516 - 112,311,114 (-)Ensembl
GRCm382112,478,733 - 112,536,361 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2112,479,171 - 112,480,769 (-)EnsemblGRCm38mm10GRCm38
MGSCv372112,319,229 - 112,320,974 (-)NCBIGRCm37mm9NCBIm37
MGSCv362112,280,010 - 112,281,608 (-)NCBImm8
Celera2113,630,348 - 113,632,093 (-)NCBICelera
Cytogenetic Map2E3NCBI
cM Map257.02NCBI
Chrm5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2399,284,846 - 99,337,252 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl399,284,846 - 99,337,252 (-)Ensembl
Rnor_6.03103,966,451 - 104,018,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3103,966,451 - 104,018,861 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03110,560,292 - 110,632,938 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4398,326,809 - 98,378,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1398,223,400 - 98,274,959 (-)NCBI
Celera398,270,221 - 98,321,572 (-)NCBICelera
Cytogenetic Map3q35NCBI
CHRM5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11531,315,839 - 31,408,563 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1531,406,198 - 31,407,796 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01512,478,656 - 12,575,512 (+)NCBIMhudiblu_PPA_v0panPan3
CHRM5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.130988,764 - 1,074,599 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl30990,208 - 991,806 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha301,033,732 - 1,118,973 (-)NCBI
ROS_Cfam_1.0301,086,979 - 1,172,509 (-)NCBI
ROS_Cfam_1.0 Ensembl301,088,172 - 1,089,832 (-)Ensembl
UMICH_Zoey_3.1301,033,678 - 1,119,068 (-)NCBI
UNSW_CanFamBas_1.0301,132,741 - 1,218,246 (-)NCBI
UU_Cfam_GSD_1.0301,260,343 - 1,345,796 (-)NCBI
Chrm5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864079,539,375 - 79,618,606 (-)NCBI
SpeTri2.0NW_0049366732,607,906 - 2,610,885 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRM5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl780,427,360 - 80,428,963 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1780,423,768 - 80,429,187 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2786,417,799 - 86,503,220 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRM5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12648,842,021 - 48,940,962 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2648,842,779 - 48,844,377 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604892,061,214 - 92,063,631 (+)NCBIVero_WHO_p1.0
Chrm5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624804255,505 - 257,103 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624804252,437 - 334,457 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005381165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01016810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000026042   ⟹   ENSCLAP00000025744
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955416526,755 - 528,353 (-)Ensembl
RefSeq Acc Id: XM_005381165   ⟹   XP_005381222
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955416526,718 - 528,353 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381222 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005381222   ⟸   XM_005381165
- Sequence:
RefSeq Acc Id: ENSCLAP00000025744   ⟸   ENSCLAT00000026042
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017868 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000025744 ENTREZGENE
  ENSCLAP00000025744.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000026042 ENTREZGENE
  ENSCLAT00000026042.1 UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Musac_Ach_M5_rcpt UniProtKB/TrEMBL
  Musac_Ach_rcpt UniProtKB/TrEMBL
NCBI Gene Chrm5 ENTREZGENE
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  MUSCARINICR UniProtKB/TrEMBL
  MUSCRINICM5R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt A0A8C2W6B8_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Chrm5  cholinergic receptor muscarinic 5    cholinergic receptor, muscarinic 5  Symbol and/or name change 5135510 APPROVED