Cdk5r2 (cyclin dependent kinase 5 regulatory subunit 2) - Rat Genome Database

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Gene: Cdk5r2 (cyclin dependent kinase 5 regulatory subunit 2) Chinchilla lanigera
Analyze
Symbol: Cdk5r2
Name: cyclin dependent kinase 5 regulatory subunit 2
RGD ID: 8858683
Description: ENCODES a protein that exhibits actin binding (ortholog); cyclin-dependent protein serine/threonine kinase activator activity (ortholog); INVOLVED IN cerebellum development (ortholog); hippocampus development (ortholog); layer formation in cerebral cortex (ortholog); ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); cerebrotendinous xanthomatosis (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); growth cone (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-dependent kinase 5 activator 2; cyclin-dependent kinase 5, regulatory subunit 2 (p39)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,472,757 - 14,473,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,471,625 - 14,474,082 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cdk5r2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545314,472,757 - 14,473,896 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545314,471,625 - 14,474,082 (-)NCBIChiLan1.0ChiLan1.0
CDK5R2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,959,666 - 218,962,155 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,959,666 - 218,962,155 (+)EnsemblGRCh38hg38GRCh38
GRCh372219,824,388 - 219,826,877 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,532,642 - 219,535,121 (+)NCBINCBI36Build 36hg18NCBI36
Build 342219,649,902 - 219,652,381NCBI
Celera2213,594,140 - 213,596,619 (+)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2211,678,607 - 211,680,905 (+)NCBIHuRef
CHM1_12219,831,707 - 219,834,234 (+)NCBICHM1_1
T2T-CHM13v2.02219,448,040 - 219,450,529 (+)NCBIT2T-CHM13v2.0
Cdk5r2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,894,188 - 74,896,891 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,894,093 - 74,896,891 (+)EnsemblGRCm39 Ensembl
GRCm38174,855,029 - 74,857,732 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,854,934 - 74,857,732 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,901,603 - 74,904,306 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,788,305 - 74,789,414 (+)NCBIMGSCv36mm8
Celera175,410,113 - 75,412,816 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.54NCBI
Cdk5r2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,864,922 - 83,866,390 (+)NCBIGRCr8
mRatBN7.2976,416,251 - 76,417,719 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl976,416,062 - 76,418,344 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,861,411 - 84,862,879 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,990,363 - 89,991,831 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0988,376,512 - 88,377,980 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0982,120,059 - 82,121,527 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl982,120,059 - 82,121,527 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,888,640 - 81,890,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4974,191,842 - 74,193,310 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera973,987,770 - 73,989,238 (+)NCBICelera
Cytogenetic Map9q33NCBI
CDK5R2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213121,590,822 - 121,593,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B121,605,794 - 121,608,306 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B106,217,926 - 106,220,444 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,810,584 - 224,813,739 (+)NCBIpanpan1.1PanPan1.1panPan2
CDK5R2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13725,528,934 - 25,535,795 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3725,529,151 - 25,530,263 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3726,349,294 - 26,350,503 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03725,544,512 - 25,545,721 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13725,449,138 - 25,450,347 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03725,384,173 - 25,385,381 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03725,404,961 - 25,406,170 (+)NCBIUU_Cfam_GSD_1.0
Cdk5r2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303175,038,311 - 175,040,812 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365691,381,262 - 1,382,365 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365691,381,101 - 1,383,593 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK5R2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,985,257 - 120,986,354 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115120,985,069 - 120,990,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,924,680 - 133,927,298 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK5R2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,858,260 - 104,860,795 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,858,461 - 104,859,564 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604094,532,588 - 94,535,131 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk5r2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,053,550 - 6,054,659 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,053,469 - 6,054,748 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000012046   ⟹   ENSCLAP00000011906
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545314,472,757 - 14,473,896 (-)Ensembl
RefSeq Acc Id: XM_013519766   ⟹   XP_013375220
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545314,471,625 - 14,474,082 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013375220 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000011906.1
RefSeq Acc Id: XP_013375220   ⟸   XM_013519766
- UniProtKB: A0A8C2V967 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000011906   ⟸   ENSCLAT00000012046


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008214 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000012046.1 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/TrEMBL
InterPro CDK5_activator UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/TrEMBL
NCBI Gene Cdk5r2 ENTREZGENE
PANTHER CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 2 UniProtKB/TrEMBL
  PTHR23401 UniProtKB/TrEMBL
Pfam CDK5_activator UniProtKB/TrEMBL
PIRSF Cdk5_activator UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/TrEMBL
UniProt A0A8C2V967 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cdk5r2  cyclin dependent kinase 5 regulatory subunit 2    cyclin-dependent kinase 5, regulatory subunit 2 (p39)  Symbol and/or name change 5135510 APPROVED