Minar2 (membrane integral NOTCH2 associated receptor 2)

Gene: Minar2 (membrane integral NOTCH2 associated receptor 2) Chinchilla lanigera

Analyze

Symbol:

Minar2

Name:

membrane integral NOTCH2 associated receptor 2

RGD ID:

8858559

Description:

ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN angiogenesis (ortholog); exploration behavior (ortholog); gene expression (ortholog); ASSOCIATED WITH Autosomal Recessive Nonsyndromic Deafness 120 (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN endoplasmic reticulum (ortholog); lysosomal membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

KIAA1024 like; KIAA1024-like ortholog; Kiaa1024l; UPF0258 protein KIAA1024-like homolog

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	2,626,926 - 2,644,610 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	2,627,047 - 2,644,602 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Autosomal Recessive Nonsyndromic Deafness 120 (ISO)

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Parkinson's disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (ISO)

exploration behavior (ISO)

gene expression (ISO)

locomotory behavior (ISO)

neuron apoptotic process (ISO)

walking behavior (ISO)

Cellular Component

endoplasmic reticulum (ISO)

lysosomal membrane (ISO)

Molecular Function

cholesterol binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Minar2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	2,626,926 - 2,644,610 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	2,627,047 - 2,644,602 (+)	NCBI	ChiLan1.0	ChiLan1.0

MINAR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	129,748,094 - 129,766,732 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	129,748,094 - 129,766,732 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	129,083,787 - 129,102,425 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	129,111,783 - 129,128,655 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	125,214,247 - 125,231,116 (+)	NCBI		Celera
Cytogenetic Map	5	q23.3	NCBI
HuRef	5	124,275,579 - 124,292,449 (+)	NCBI		HuRef
CHM1_1	5	128,516,482 - 128,533,358 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	130,266,871 - 130,285,510 (+)	NCBI		T2T-CHM13v2.0

Minar2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	59,195,264 - 59,210,034 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	59,195,320 - 59,210,034 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	59,062,189 - 59,076,962 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	59,062,248 - 59,076,962 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	59,222,035 - 59,236,616 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	59,187,878 - 59,202,326 (+)	NCBI		MGSCv36	mm8
Celera	18	60,372,082 - 60,383,212 (+)	NCBI		Celera
Cytogenetic Map	18	D3	NCBI
cM Map	18	33.9	NCBI

Minar2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	54,737,670 - 54,752,388 (+)	NCBI		GRCr8
mRatBN7.2	18	52,539,714 - 52,554,465 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	52,539,917 - 52,554,461 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	54,567,309 - 54,581,786 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	55,281,889 - 55,296,371 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	53,090,588 - 53,105,137 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	54,108,471 - 54,123,061 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	54,108,493 - 54,123,049 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	53,346,440 - 53,361,034 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	54,856,686 - 54,870,235 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	54,929,156 - 54,942,513 (+)	NCBI
Celera	18	50,644,005 - 50,658,542 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

MINAR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	125,058,379 - 125,077,947 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	123,197,941 - 123,217,509 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	125,163,230 - 125,182,801 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	131,335,020 - 131,351,901 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	131,335,020 - 131,353,934 (+)	Ensembl	panpan1.1		panPan2

MINAR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	18,506,042 - 18,531,187 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	18,507,059 - 18,524,589 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	17,305,450 - 17,332,029 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	19,260,965 - 19,287,961 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	19,262,163 - 19,282,883 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	17,985,402 - 18,012,018 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	17,819,766 - 17,844,986 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	18,433,417 - 18,460,805 (+)	NCBI		UU_Cfam_GSD_1.0

Minar2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	141,256,345 - 141,273,817 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	2,830,236 - 2,847,847 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936504	2,830,286 - 2,847,785 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MINAR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	132,416,040 - 132,428,922 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	132,413,265 - 132,428,786 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	137,754,060 - 137,767,110 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MINAR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	32,655,661 - 32,672,945 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	32,655,735 - 32,674,117 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	45,337,139 - 45,354,353 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Minar2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	11,607,504 - 11,623,544 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	11,607,603 - 11,623,582 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005380556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01015907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCQ01188629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000013719 ⟹ ENSCLAP00000013565

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955415	2,626,926 - 2,644,610 (+)	Ensembl

RefSeq Acc Id:

XM_005380556 ⟹ XP_005380613

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955415	2,627,047 - 2,644,602 (+)	NCBI

Sequence:

show sequence

GCTTTGTTCTTGTGAGTTGATGTGTCATTTCAAGAACGGACTGGGGGCACCTGGTTTCAGATGC
CAGTTGGAGCATCCTCAGGCTCATTAATAATGGAGGAGTCTGGCCGGAGCAGCCTTGCTCGCCT
TTGTTTCCCCTGGAGAAGACGGGAGACATGGATCTTTCTGTTTTGCCCAATAACAACCATCCTG
ACAAATTCCTGCAGCTTGATGTGAAGTCTCTAATGAAGAGCCCGGCCCTGCAGCAGGCCAGTCT
TGTGAGACTGCTGGGTGGAAACTACCCTGCTGCACAACACTGGCAAAACCTTGTCTACTCACAG
AAAGAAAAGAAGAATGTCACTGCTCAACGAGTCAAAGGATCCAGCGGGGTGGTCTCTGTCATTG
CCGATAGCCCTCCACCATCCATGTCCTCAGTTATGAAAAATAACCCACTCTATGGTGACATAAG
TTTGGAAGAAGCTATGGAAGAAAGAAAAAAAAGTCCTTCCTGGACTATTGAGGAGTATGACAAG
CATTCTTTGCACACAAACCTCTCTGGACATCTAAAGGAAAACCCTAACGACCTACGGTTTTGGT
TGGGAGACATGTACACACCGGGTTTTGACACCTTGTTGAAAAAGAAAAAGAAGCACGACAAGCA
ATCAAAATTATGTCGTGTAGGTTTGATTGTTCTCCTTGTTGCCTCCATCTTGATAACCATAGTG
ACTGTCAGCACTTTATTCACCTAAAGAAACTGCCACAGAGCCACCTTCCATTTTTAAACAAGAC
TCATAAATATGTGCAAAGAAGTCTTCATGTAGTATGAATGTGCCGTTGATTGTACAATTAAAGG
TCATTGCTCTGTGGAATGTGAGCATCGTTTATGATACGCCCCGTTTCGTTCTCTGGAACCTGTG
TACAAATTCCAGCCTGCACTTTTTCCTTTGGGAAGCAAATCTGAGGATCACAACCACAGAAAAG
CCATTATACAAGCAAAGTTAAACATTCTTATCGAGGAAAAACCAGCATCAGTGATTATCAGCAG
CAATGTCTCAATACTGAAACTTTCTTTGCCTTACTTTAAAAATACCACCAGTTCCTCTTCACCC
CTTCCACCTAAGGCACTATGGAAGACTGACCTGGTCATTGTTGGACCAAGAACCAGGTAGACAA
GCCAAAAGCTTTTAGTTGTGCTGTCAGTTGGTTTGGAGTCATTCTCTGTCTTATCTTCCTTTAT
TGCTGTATAAGTCAGCTGGGGGAAAAAAAGTGTTGGGGGAAGAGTTTGCTCAATTCTATTCTTA
TTTTCTAAGTATTTTTCGTAATACACCTAGTGTTCCATTTAGCAAAACTAAACTTGGACAAGTC
ATAGTGCTGTGGTTAATTATATTTTGACCCAATTGTGCTTATTAATTGATCCAAATTGTCTAGT
GTGACCTCTGATAGAGGTCAATATATGTCGCCAGCCATGGTCTAGCTGGAAGGCCCTAGAAAAG
CAAAAGACATTGCCAAAAGAATGAGTTTGAGCTCTGACCATGACATTGTTAAACTATTGGACCC
CAAGCAATATATTTTCTCAGAGAAGGGATAACACCACCTCCCCAGTGAAGCTGACTAAGGCTAA
ATAAGAAACAGAAGTGAGAACAATGCCAGGCTCCCAGGATTTAATTGCTTAGTTAGTGGCAGTT
GTTATTACTGATTTATGTCAGCTGAGTGGCATCCTGGGCTCATCTTTCCTGGCCTGCAGATAAT
TGGGCACAGGGTTCTGGGTGTAGATCATGCAGCTGCTGCTCTCCTGTCCTCCCACAGAATCCTT
CCCTGAGGCCCTCACTGCCGCTCCTTCCTCTTCTTTAGAAGTCACTCTGAAGATGTCTTGTGCA
TGAAACGAAAGAGGGTCTTTCTCCTTTTCCCCTTAGCCTAAAGTATGCTTTTGTTCCTTGACTT
TTCCATATTATTTTGTATATTTCTCTTAATACATATTTGAAACCAAGCACATTAAAGCACAGCT
TTCCTGGTCAATAAAATCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005380613	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000013565
	ENSCLAP00000013565.1

RefSeq Acc Id:	XP_005380613 ⟸ XM_005380556
- UniProtKB:	A0A8C2VE65 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLSVLPNNNHPDKFLQLDVKSLMKSPALQQASLVRLLGGNYPAAQHWQNLVYSQKEKKNVTAQ RVKGSSGVVSVIADSPPPSMSSVMKNNPLYGDISLEEAMEERKKSPSWTIEEYDKHSLHTNLSG HLKENPNDLRFWLGDMYTPGFDTLLKKKKKHDKQSKLCRVGLIVLLVASILITIVTVSTLFT hide sequence

RefSeq Acc Id:

ENSCLAP00000013565 ⟸ ENSCLAT00000013719

Protein Domains

Major intrinsically disordered Notch2-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009373	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013719	ENTREZGENE
	ENSCLAT00000013719.1	UniProtKB/TrEMBL
InterPro	MINAR1-like	UniProtKB/TrEMBL
	MINAR1-like_C	UniProtKB/TrEMBL
NCBI Gene	Kiaa1024l	ENTREZGENE
PANTHER	MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE	UniProtKB/TrEMBL
	PTHR31530	UniProtKB/TrEMBL
Pfam	MINAR1_C	UniProtKB/TrEMBL
UniProt	A0A8C2VE65	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-01	Minar2	membrane integral NOTCH2 associated receptor 2	Kiaa1024l	KIAA1024 like	Symbol and/or name change	5135510	APPROVED
2016-08-03	Kiaa1024l	KIAA1024 like		KIAA1024-like ortholog	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM