Mtap (methylthioadenosine phosphorylase) - Rat Genome Database

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Gene: Mtap (methylthioadenosine phosphorylase) Chinchilla lanigera
Analyze
Symbol: Mtap
Name: methylthioadenosine phosphorylase
RGD ID: 8855161
Description: ENCODES a protein that exhibits S-methyl-5-thioadenosine phosphorylase activity (ortholog); INVOLVED IN methylation (ortholog); nicotinamide riboside catabolic process (ortholog); response to testosterone (ortholog); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; ASSOCIATED WITH biliary tract benign neoplasm (ortholog); common bile duct neoplasm (ortholog); diaphyseal medullary stenosis with malignant fibrous histiocytoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: S-methyl-5'-thioadenosine phosphorylase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547212,390,032 - 12,439,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547212,391,399 - 12,439,221 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547212,390,032 - 12,439,206 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547212,391,399 - 12,439,221 (-)NCBIChiLan1.0ChiLan1.0
MTAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38921,802,636 - 21,941,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl921,802,636 - 21,937,651 (+)EnsemblGRCh38hg38GRCh38
GRCh37921,802,635 - 21,941,114 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36921,792,635 - 21,855,970 (+)NCBINCBI36Build 36hg18NCBI36
Build 34921,792,634 - 21,855,967NCBI
Celera921,740,998 - 21,804,334 (+)NCBICelera
Cytogenetic Map9p21.3NCBI
HuRef921,765,963 - 21,829,332 (+)NCBIHuRef
CHM1_1921,802,515 - 21,865,858 (+)NCBICHM1_1
T2T-CHM13v2.0921,816,863 - 21,955,417 (+)NCBIT2T-CHM13v2.0
Mtap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39489,055,607 - 89,099,327 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl489,055,359 - 89,099,318 (+)EnsemblGRCm39 Ensembl
GRCm38489,137,370 - 89,181,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl489,137,122 - 89,181,081 (+)EnsemblGRCm38mm10GRCm38
MGSCv37488,783,274 - 88,826,994 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36488,608,657 - 88,652,314 (+)NCBIMGSCv36mm8
Celera487,620,095 - 87,663,899 (+)NCBICelera
Cytogenetic Map4C4NCBI
cM Map442.15NCBI
Mtap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85108,990,270 - 109,036,494 (+)NCBIGRCr8
mRatBN7.25103,874,460 - 103,920,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5103,873,020 - 103,939,406 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5106,308,258 - 106,354,482 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05108,037,874 - 108,084,086 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05108,118,643 - 108,164,834 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05107,711,077 - 107,777,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5107,711,077 - 107,777,530 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05111,679,661 - 111,746,208 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45108,788,725 - 108,861,905 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15108,793,950 - 108,867,131 (+)NCBI
Celera5102,587,860 - 102,654,739 (+)NCBICelera
Cytogenetic Map5q32NCBI
MTAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211102,620,519 - 102,756,196 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19102,623,086 - 102,762,138 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0921,637,543 - 21,769,698 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1922,253,357 - 22,316,883 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl922,266,376 - 22,382,218 (+)Ensemblpanpan1.1panPan2
MTAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11141,148,389 - 41,200,635 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1141,148,404 - 41,264,504 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1139,820,541 - 39,872,745 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01142,090,758 - 42,142,952 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1142,090,124 - 42,142,944 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11140,760,953 - 40,813,082 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01140,648,752 - 40,701,001 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01141,262,101 - 41,314,256 (+)NCBIUU_Cfam_GSD_1.0
Mtap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947155,762,052 - 155,800,008 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366523,431,171 - 3,472,071 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366523,431,588 - 3,468,770 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1200,882,956 - 200,934,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11200,882,954 - 200,934,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,075,795 - 224,126,822 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11584,196,548 - 84,198,357 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1257,997,427 - 58,050,241 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604157,778,455 - 57,780,270 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473625,778,240 - 25,826,530 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473625,778,191 - 25,826,945 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000002435   ⟹   ENSCLAP00000002384
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547212,390,032 - 12,439,206 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000002436   ⟹   ENSCLAP00000002385
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547212,390,032 - 12,427,523 (-)Ensembl
RefSeq Acc Id: XM_005401168   ⟹   XP_005401225
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547212,391,399 - 12,439,221 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005401169   ⟹   XP_005401226
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547212,391,399 - 12,437,915 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401225 (Get FASTA)   NCBI Sequence Viewer  
  XP_005401226 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002384
  ENSCLAP00000002384.1
  ENSCLAP00000002385.1
RefSeq Acc Id: XP_005401225   ⟸   XM_005401168
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UMQ2 (UniProtKB/TrEMBL),   A0A8C2YJ32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401226   ⟸   XM_005401169
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YJ32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002385   ⟸   ENSCLAT00000002436
RefSeq Acc Id: ENSCLAP00000002384   ⟸   ENSCLAT00000002435
Protein Domains
Nucleoside phosphorylase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001731 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002435 ENTREZGENE
  ENSCLAT00000002435.1 UniProtKB/TrEMBL
  ENSCLAT00000002436.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1580 UniProtKB/TrEMBL
InterPro MTAP UniProtKB/TrEMBL
  Nucleoside_phosphorylase_d UniProtKB/TrEMBL
  Nucleoside_phosphorylase_sf UniProtKB/TrEMBL
  Purine_phosphorylase-2_CS UniProtKB/TrEMBL
NCBI Gene Mtap ENTREZGENE
PANTHER PTHR42679 UniProtKB/TrEMBL
  S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE UniProtKB/TrEMBL
Pfam PNP_UDP_1 UniProtKB/TrEMBL
PROSITE PNP_MTAP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53167 UniProtKB/TrEMBL
UniProt A0A8C2UMQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YJ32 ENTREZGENE, UniProtKB/TrEMBL