Poldip2 (DNA polymerase delta interacting protein 2)

Gene: Poldip2 (DNA polymerase delta interacting protein 2) Chinchilla lanigera

Analyze

Symbol:

Poldip2

Name:

DNA polymerase delta interacting protein 2

RGD ID:

8854423

Description:

INVOLVED IN error-free translesion synthesis (ortholog); mitochondrion organization (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH Neointima (ortholog); streptococcal meningitis (ortholog); FOUND IN cell-cell junction (ortholog); midbody (ortholog); mitochondrial matrix (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

polymerase (DNA-directed), delta interacting protein 2; polymerase delta-interacting protein 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,776,721 - 4,785,817 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	4,776,721 - 4,785,817 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neointima (ISO)

streptococcal meningitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

error-free translesion synthesis (ISO)

mitochondrion organization (ISO)

mitotic spindle assembly (ISO)

negative regulation of macroautophagy (ISO)

positive regulation of actin filament binding (ISO)

positive regulation of focal adhesion assembly (ISO)

positive regulation of mitotic cell cycle (ISO)

positive regulation of mitotic cytokinesis (ISO)

positive regulation of Rho guanyl-nucleotide exchange factor activity (ISO)

vascular associated smooth muscle cell proliferation (ISO)

Cellular Component

cell-cell junction (ISO)

midbody (ISO)

mitochondrial matrix (ISO)

mitochondrial nucleoid (ISO)

mitochondrion (ISO)

mitotic spindle (ISO)

nucleus (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Poldip2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,776,721 - 4,785,817 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955481	4,776,721 - 4,785,817 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLDIP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	28,346,633 - 28,357,527 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	28,346,633 - 28,357,527 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	26,673,659 - 26,684,550 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	23,697,786 - 23,708,730 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	23,697,786 - 23,708,693	NCBI
Celera	17	23,535,404 - 23,546,357 (-)	NCBI		Celera
Cytogenetic Map	17	q11.2	NCBI
HuRef	17	22,882,056 - 22,893,008 (-)	NCBI		HuRef
CHM1_1	17	26,736,554 - 26,747,532 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	29,288,484 - 29,299,376 (-)	NCBI		T2T-CHM13v2.0

Poldip2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	78,403,105 - 78,413,562 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	78,403,019 - 78,413,562 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	78,512,296 - 78,522,736 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	78,512,193 - 78,522,736 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	78,325,798 - 78,336,238 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	78,328,491 - 78,338,931 (+)	NCBI		MGSCv36	mm8
Celera	11	88,144,369 - 88,154,809 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	46.74	NCBI

Poldip2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	63,905,287 - 63,915,655 (+)	NCBI		GRCr8
mRatBN7.2	10	63,407,237 - 63,417,605 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	63,407,213 - 63,417,605 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	68,039,879 - 68,050,258 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	67,545,210 - 67,555,589 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	63,014,737 - 63,025,106 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	65,781,994 - 65,790,833 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	65,780,494 - 65,790,272 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	65,852,787 - 65,861,626 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	64,623,181 - 64,632,020 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	64,635,612 - 64,645,643 (+)	NCBI
Celera	10	62,385,321 - 62,394,160 (+)	NCBI		Celera
Cytogenetic Map	10	q25	NCBI

POLDIP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	36,101,061 - 36,111,471 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	37,981,489 - 37,991,863 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	28,416,912 - 28,427,280 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	28,919,291 - 28,929,613 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	28,919,371 - 28,928,682 (+)	Ensembl	panpan1.1		panPan2

POLDIP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	42,597,792 - 42,607,576 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	42,597,792 - 42,607,576 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	41,754,715 - 41,764,504 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	43,416,944 - 43,426,747 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	43,416,944 - 43,426,773 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	42,201,185 - 42,210,981 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	42,492,418 - 42,502,205 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	42,569,460 - 42,579,263 (-)	NCBI		UU_Cfam_GSD_1.0

Poldip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	41,626,091 - 41,634,827 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	4,500,478 - 4,512,761 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	4,504,039 - 4,512,785 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLDIP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	44,625,604 - 44,636,289 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	44,626,447 - 44,636,302 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	46,538,915 - 46,548,765 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLDIP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	22,113,928 - 22,124,637 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	22,110,641 - 22,124,301 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	8,004,364 - 8,014,832 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Poldip2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	948,923 - 961,800 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	943,015 - 961,828 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005402761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01056952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01009609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01062561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000015637 ⟹ ENSCLAP00000015475

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955481	4,776,721 - 4,785,817 (+)	Ensembl

RefSeq Acc Id:

XM_005402761 ⟹ XP_005402818

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	4,776,721 - 4,785,817 (+)	NCBI

Sequence:

show sequence

CCCCCCCCCCCCCCCCCCCCGCGGCCCCCCGGCCCCGCGCGTCCCTCCGCGCCGCCCCCGCGCC
GGCCCCCGAGCTGCGCGGCGGGGGCGGGGCGCCGCCCGGCCGCGGGTCGGGCCCTGTGTCGGCA
GCCGGGCGGGCGCTCCGGCCGGACATGGCTGCTTGTGTGGCCCGGCGGGCCCTGGCCGTGGGCA
GCCGCTGGTGGTCCCGGTCTCTGACCGCTGCCCGAGGGTCGAGGCCGCTGTGTGCCGCGGGGGG
AGCACCGGGCTTCCCACCTGCGGCGACTACGACGACGCAGAGGCATCTCTCGTCCCGAAACCGA
GCGGAGGGCAAAGTATTGGAGACAGTTGGTGTGTTTGAGGTGCCAAAACAGAACGGAAAATACG
AGACTGGGCAGCTTTTTCTTCATAGTGTTTTTGGCTACCGAGGTGTTGTCCTGTTTCCCTGGCA
GGCCAGACTATATGACCGGGATGTGGCTTCTGCAGCTTCAGAAAAAGCGGAGAATCCTGCTGGC
CACGGCTCTAAGGAGGTGAAAGGCAAAACTCACACTTACTATCAGGTGCTGATTGATGCCCGAG
ACTGTCCACATATATCTCAGAGATCTCAGACAGAAGCTGTGACCTTCTTGGCTAACCATGATGA
CAGCCGGGCCCTCTATGCCATTCCAGGCCTGGACTATGTCAGCCATGAAGACATCCTCCCCTAC
ACCTCCACCGACCAGGTTCCCATCCAGCATGAGCTCTTTGAAAGATTTCTTCTGTATGACCAGA
CGAAAGCGCCCCCTTTTGTGGCTCGGGAAACGCTGCGGGCCTGGCAAGAGAAGAACCACCCTTG
GCTAGAGCTGTCCGACGTCCACCGGGAGACAACCGAGAACATCCGTGTCACTGTCATCCCTTTC
TACATGGGCATGAGGGAAGCCCAGAATTCCCATGTCTACTGGTGGCGCTACTGTATCCGCTTAG
AGAACCTGGACAGTGATGTGGTGCAGCTCCGGGAGCGGCACTGGAGGATATTTAGCCTCTCGGG
CACCTTGGAGACAGTGCGAGGCCGAGGGGTGGTGGGCAGGGAACCAGTGTTGTCCAAAGAGCAG
CCGGCATTCCAGTACAGCAGCCATGTCTCCCTGCAGGCCTCTAGTGGGCACATGTGGGGTACGT
TCCGCTTCGAGAGACCTGATGGCTCCCACTTTGATGTCCGGATCCCACCTTTCTCCTTGGAAAG
CAATAAAGATGAGAAGACACCACCCTCAGGCCTTCACTGGTAGGCCAGCTGAGGCCTTGCGTGC
CTAGGCTTGGCCCCTCAGATCAGCTGTAAACCCACAATTGCTGCAAAACTCCTTTCTCCCCCAT
CATGGCCCAAATGGGTCTCTTCATCCTTTGCACATTTGATTGTGGGGCTCTATCTTTTGCGGGG
TGTAGTATGTGTTTTCTTGAGAAGGCCCATGTAGGACTCCTCTAAGGCTGGCCGGCTTCCTCCT
AAGCCCTGCCTATCTCGTGTTCCCATAAACCTTTCCATCAAGGAACTGTTCAGCGGCCACAGGC
CTGGAGGAGTTTCCTGACCTGTCACAAGTTGTCTGGAACATGAAGTTTGGTCAATAAACTAGTG
CTCGCCATTTCTGCTCTCAGGGTCTCAGGCTCCCTTTCTGACCCAGTGGGGGCCCTTGATCGCT
TCCCATGTAGTCACTTCCAGGGAGCTGCCCTCTCTGCTAGGCCTTGTGTCTTTTCCCCTGAGCC
TGGAGGCTGGTTGGACATATCTTGCAGGCACTACCTCTTGCCAGCGAGTGGGTGCTGGACTGGA
CTCTTGTTCTCGTCTTTCGCCTCTGCCAAGTGCAGAGGAGGCCAGTGTCGGGGCTGGAGTGGCC
TGGCTCTTAGCACTGACCACCAGCATCTCTGGCCTTGCTGGGCTGGGAAAGGAGTGGTGAGCCC
GTCGGGTTTCCTGGCACACTGAGTTTGCCTGCTGTGCCTATCCACGCCGCAAGTGCAGGAATTT
GGCCAAGGAACAGCTTAAAGTATGGACAGTGACCAAGCCACCTACTTTAAGAGCTTCTTAGATC
TCCAAGAGCCAAAGAAGTTGGGAAGTATTTTGCCCCACTTCTTAGGATTCCTTCCCTCCTCCTA
CTGCAGTGATTGTTATAGGTAGGTTCATTTTTGAATTAATATTAAAATCACAGTTCCAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005402818	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000015475
	ENSCLAP00000015475.1

RefSeq Acc Id:

XP_005402818 ⟸ XM_005402761

- UniProtKB:

A0A8C2VNP6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAACVARRALAVGSRWWSRSLTAARGSRPLCAAGGAPGFPPAATTTTQRHLSSRNRAEGKVLET
VGVFEVPKQNGKYETGQLFLHSVFGYRGVVLFPWQARLYDRDVASAASEKAENPAGHGSKEVKG
KTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPI
QHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQ
NSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSH
VSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW

hide sequence

RefSeq Acc Id:

ENSCLAP00000015475 ⟸ ENSCLAT00000015637

Protein Domains

ApaG

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000010645	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000015637	ENTREZGENE
	ENSCLAT00000015637.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.1470	UniProtKB/TrEMBL
InterPro	ApaG_domain	UniProtKB/TrEMBL
	ApaG_sf	UniProtKB/TrEMBL
	Hemimethylated_DNA-bd_dom	UniProtKB/TrEMBL
	Hemimethylated_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	Poldip2	ENTREZGENE
PANTHER	F-BOX ONLY PROTEIN 3	UniProtKB/TrEMBL
	POLYMERASE DELTA-INTERACTING PROTEIN 2	UniProtKB/TrEMBL
Pfam	DUF525	UniProtKB/TrEMBL
	YccV-like	UniProtKB/TrEMBL
PROSITE	APAG	UniProtKB/TrEMBL
SMART	YccV-like	UniProtKB/TrEMBL
Superfamily-SCOP	SSF110069	UniProtKB/TrEMBL
	SSF141255	UniProtKB/TrEMBL
UniProt	A0A8C2VNP6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-26	Poldip2	DNA polymerase delta interacting protein 2		polymerase (DNA-directed), delta interacting protein 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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