Trappc6b (trafficking protein particle complex subunit 6B)

Gene: Trappc6b (trafficking protein particle complex subunit 6B) Chinchilla lanigera

Analyze

Symbol:

Trappc6b

Name:

trafficking protein particle complex subunit 6B (Ensembl:trafficking protein particle complex 6B)

RGD ID:

8853668

Description:

ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

trafficking protein particle complex 6B

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	22,117,329 - 22,134,236 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	22,117,329 - 22,131,102 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

genetic disease (ISO)

neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Trappc6b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	22,117,329 - 22,134,236 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	22,117,329 - 22,131,102 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRAPPC6B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	39,147,814 - 39,170,333 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	39,147,811 - 39,170,532 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	39,617,018 - 39,639,537 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	38,686,766 - 38,709,385 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	38,686,767 - 38,709,269	NCBI
Celera	14	19,481,624 - 19,504,242 (-)	NCBI		Celera
Cytogenetic Map	14	q21.1	NCBI
HuRef	14	19,731,206 - 19,753,818 (-)	NCBI		HuRef
CHM1_1	14	39,615,619 - 39,638,238 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	33,336,495 - 33,359,014 (-)	NCBI		T2T-CHM13v2.0

Trappc6b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	59,089,878 - 59,108,258 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	59,089,878 - 59,108,258 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	59,043,092 - 59,061,472 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	59,043,092 - 59,061,472 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	60,144,079 - 60,162,448 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	59,961,104 - 59,979,473 (-)	NCBI		MGSCv36	mm8
Celera	12	60,203,219 - 60,221,577 (-)	NCBI		Celera
Cytogenetic Map	12	C1	NCBI
cM Map	12	25.99	NCBI

Trappc6b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	82,475,794 - 82,486,928 (-)	NCBI		GRCr8
mRatBN7.2	6	76,740,898 - 76,752,035 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	76,740,898 - 76,752,024 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	77,187,064 - 77,198,154 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	77,486,388 - 77,497,478 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	76,913,864 - 76,924,954 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	80,142,126 - 80,153,216 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	80,142,122 - 80,153,231 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	89,667,998 - 89,679,088 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	79,741,788 - 79,752,878 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	79,744,843 - 79,755,885 (-)	NCBI
Celera	6	75,501,186 - 75,512,276 (-)	NCBI		Celera
Cytogenetic Map	6	q23	NCBI

TRAPPC6B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	40,481,089 - 40,504,302 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	39,697,601 - 39,720,834 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	19,917,745 - 19,940,589 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	38,273,526 - 38,296,231 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	38,273,526 - 38,296,231 (-)	Ensembl	panpan1.1		panPan2

TRAPPC6B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	17,335,060 - 17,350,163 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	17,336,154 - 17,350,000 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	17,146,239 - 17,161,330 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	17,457,294 - 17,472,389 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	17,457,298 - 17,472,272 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	17,144,880 - 17,159,970 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	17,216,547 - 17,231,644 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	17,503,145 - 17,518,233 (-)	NCBI		UU_Cfam_GSD_1.0

Trappc6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	49,234,099 - 49,252,803 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936494	12,740,268 - 12,758,662 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936494	12,740,268 - 12,758,697 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRAPPC6B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	169,709,558 - 169,722,735 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	169,710,948 - 169,722,782 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	188,414,028 - 188,425,855 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRAPPC6B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	15,921,318 - 15,943,926 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	15,922,995 - 15,943,842 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	4,964,767 - 4,987,383 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trappc6b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	8,600,536 - 8,615,746 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	8,598,451 - 8,615,687 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005376885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01010017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01010018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01010019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01010020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01086623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000013696 ⟹ ENSCLAP00000013542

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955409	22,117,329 - 22,134,236 (+)	Ensembl

RefSeq Acc Id:

ENSCLAT00000013697 ⟹ ENSCLAP00000013543

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955409	22,117,620 - 22,130,053 (+)	Ensembl

RefSeq Acc Id:

XM_005376885 ⟹ XP_005376942

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955409	22,117,329 - 22,131,102 (+)	NCBI

Sequence:

show sequence

CCCGCCCAGGGCCGGGCTGGTCTCCGCGGTCTGGGTTTAGTTCCAGCCCCTCGCTGTTAGGTCG
TCGCTCTGGGCCCTCGGGCTCGGTTCCCCCAGGGTGGTTCCTCCCTGTTGTCGGGCTCACCCGG
TTGCGACCTTTGGGAGGCCCAGTGCAATTTTCAGTGTCCTAGCAACGGGGGACAGGGCCGCCGT
CGGAGGAAGTGGGCGCCGGCCTCGTCGCTGCGGCGCTGGCCGGAACCCCCGGCCGGCCCAGTCG
ACAGCTGAAACCCGGAGCTCGGAAGGAAGGCGGACATGGCGGACGAGGCGTTGTTTTTGCTTCT
CCATAACGAGATGGTGTCGGGAGTGTACAAGTCTGCGGAGCAGGGGGAGGTGGAAAATGGGCGA
TGTATTACTAAGCTGGAAAACATGGGGTTTCGAGTGGGACAAGGATTGATAGAAAGGTTTACAA
AAGATACTGCAAGGTTCAAGGATGAGTTAGACATCATGAAGTTCATTTGTAAAGATTTTTGGAC
TACAGTATTCAAGAAACAAATCGACAATCTAAGGACAAATCATCAGGGCATCTATGTACTTCAG
GACAACAAATTTCGTCTGCTTACTCAGATGTCTGCGGGAAAACAGTATTTAGAGCATGCATCTA
AGTATCTAGCATTTACATGTGGCTTAATCAGAGGTGGTTTATCAAACTTGGGAATAAAAAGTAT
TGTAACTGCTGAAGTGTCTTCAATGCCTGCTTGTAAATTTCAGGTGATGATACAGAAGCTATAA
ACGTACTGAAATGCAAGACTTCCACAGTGTAAAGACATAAATTATTCATGTGTAAAGCATTTCA
AGTAGTAACGATTTAATTACACTGTTGGATGTTTGTACAGGAGTGAGGGTATATGTTATCAATT
TAATGCAGACCAACTTAAAGCAGATAAAGGGTCATTCTACCACGGGATAAACTTTAATGAAACT
GTTCAAAATGGAAGCTTGATTTCAAATAACTGGACACCAAAATGTATCTTAAATATGTTTTACT
TACTTGGAGTGATAGCCACAGCTGTAATGTAGGGTCTGTTTTGGTGGCACAGAGAAAAACAGGC
ACCAGCCAGAATCGTTGGTGTTTAGAGTGACTGACGCTGGGTAGATAAAATGTGAGTCTGTTTC
AGTTACTTTTAAAAAGCAAATAATACACTAAATTAAGTTTAACTTTTTATTTTGTTGCTTATAA
TTTATTTTTATGACTGTGTAAGGACTTCATGTATACATTGTGTGTATGTGTGTGCATGTAAATA
TAAAAATACAAACATGACCTTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005376942	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000013542
	ENSCLAP00000013542.1
	ENSCLAP00000013543.1

RefSeq Acc Id:	XP_005376942 ⟸ XM_005376885
- UniProtKB:	A0A8C2VGA4 (UniProtKB/TrEMBL), A0A8C2VIZ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI MKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRG GLSNLGIKSIVTAEVSSMPACKFQVMIQKL hide sequence

RefSeq Acc Id:

ENSCLAP00000013543 ⟸ ENSCLAT00000013697

RefSeq Acc Id:

ENSCLAP00000013542 ⟸ ENSCLAT00000013696

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000009363	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000013696	ENTREZGENE
	ENSCLAT00000013696.1	UniProtKB/TrEMBL
	ENSCLAT00000013697.1	UniProtKB/TrEMBL
Gene3D-CATH	Trafficking protein particle complex subunit 3	UniProtKB/TrEMBL
InterPro	NO_sig/Golgi_transp_ligand-bd	UniProtKB/TrEMBL
	TRAPP_component	UniProtKB/TrEMBL
	TRAPPC6/Trs33	UniProtKB/TrEMBL
NCBI Gene	Trappc6b	ENTREZGENE
PANTHER	PTHR12817	UniProtKB/TrEMBL
	TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B	UniProtKB/TrEMBL
Pfam	TRAPP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF111126	UniProtKB/TrEMBL
UniProt	A0A8C2VGA4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VIZ8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-02-16	Trappc6b	trafficking protein particle complex subunit 6B	Trappc6b	trafficking protein particle complex 6B	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM