Vsig4 (V-set and immunoglobulin domain containing 4) - Rat Genome Database

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Gene: Vsig4 (V-set and immunoglobulin domain containing 4) Chinchilla lanigera
Analyze
Symbol: Vsig4
Name: V-set and immunoglobulin domain containing 4
RGD ID: 8847161
Description: ENCODES a protein that exhibits complement component C3b binding (ortholog); INVOLVED IN negative regulation of complement activation, alternative pathway (ortholog); negative regulation of interleukin-2 production (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: V-set and immunoglobulin domain-containing protein 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554755,461,064 - 5,481,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554755,461,512 - 5,481,552 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Vsig4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554755,461,064 - 5,481,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554755,461,512 - 5,481,552 (-)NCBIChiLan1.0ChiLan1.0
VSIG4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X66,021,738 - 66,040,080 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX66,021,738 - 66,040,125 (-)EnsemblGRCh38hg38GRCh38
GRCh37X65,241,580 - 65,259,922 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X65,158,305 - 65,176,692 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X65,024,600 - 65,042,906NCBI
CeleraX65,588,725 - 65,607,111 (-)NCBICelera
Cytogenetic MapXq12NCBI
HuRefX59,068,686 - 59,087,663 (-)NCBIHuRef
CHM1_1X65,134,610 - 65,152,555 (-)NCBICHM1_1
T2T-CHM13v2.0X64,448,234 - 64,467,291 (-)NCBIT2T-CHM13v2.0
Vsig4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X95,290,807 - 95,337,044 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX95,290,809 - 95,337,044 (-)EnsemblGRCm39 Ensembl
GRCm38X96,247,201 - 96,293,438 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX96,247,203 - 96,293,438 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X93,442,542 - 93,488,777 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X92,449,922 - 92,496,157 (-)NCBIMGSCv36mm8
CeleraX83,251,817 - 83,298,808 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX42.69NCBI
Vsig4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X65,154,422 - 65,179,708 (-)NCBIGRCr8
mRatBN7.2X61,144,926 - 61,170,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX61,144,928 - 61,170,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX62,618,577 - 62,643,869 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X66,119,103 - 66,144,391 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X63,676,350 - 63,701,634 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X65,370,851 - 65,400,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,370,851 - 65,400,298 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X66,208,997 - 66,234,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X83,872,092 - 83,898,242 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX61,557,850 - 61,582,973 (-)NCBICelera
Cytogenetic MapXq22NCBI
VSIG4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X65,546,150 - 65,563,779 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X65,549,755 - 65,567,384 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X55,137,938 - 55,155,569 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X65,211,313 - 65,228,888 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX65,211,313 - 65,229,332 (-)Ensemblpanpan1.1panPan2
VSIG4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X50,839,979 - 50,881,684 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX50,803,330 - 50,881,618 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX41,659,551 - 41,719,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X51,785,928 - 51,845,934 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX51,806,749 - 51,845,903 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X49,750,420 - 49,810,399 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X51,098,349 - 51,158,343 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X51,013,686 - 51,073,693 (-)NCBIUU_Cfam_GSD_1.0
Vsig4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X51,402,029 - 51,426,149 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366352,167,617 - 2,191,740 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366352,167,633 - 2,191,725 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VSIG4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX52,175,607 - 52,198,566 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X52,175,601 - 52,198,635 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X58,745,331 - 58,775,852 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VSIG4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X55,963,007 - 55,982,929 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX55,962,866 - 55,981,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660833,291,053 - 3,309,343 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vsig4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248981,268,886 - 1,289,180 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248981,268,998 - 1,288,756 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000004737   ⟹   ENSCLAP00000004651
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554755,461,064 - 5,481,564 (-)Ensembl
RefSeq Acc Id: XM_013502886   ⟹   XP_013358340
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554755,461,512 - 5,481,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013502887   ⟹   XP_013358341
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554755,461,512 - 5,481,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013502888   ⟹   XP_013358342
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554755,462,209 - 5,481,552 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013358340 (Get FASTA)   NCBI Sequence Viewer  
  XP_013358341 (Get FASTA)   NCBI Sequence Viewer  
  XP_013358342 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004651
  ENSCLAP00000004651.1
RefSeq Acc Id: XP_013358341   ⟸   XM_013502887
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013358340   ⟸   XM_013502886
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UR78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358342   ⟸   XM_013502888
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000004651   ⟸   ENSCLAT00000004737
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003308 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004737 ENTREZGENE
  ENSCLAT00000004737.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  VSIG4 UniProtKB/TrEMBL
  VSIG4_IgV UniProtKB/TrEMBL
NCBI Gene Vsig4 ENTREZGENE
PANTHER PTHR15466 UniProtKB/TrEMBL
  V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8C2UR78 ENTREZGENE, UniProtKB/TrEMBL