Ppat (phosphoribosyl pyrophosphate amidotransferase) - Rat Genome Database

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Gene: Ppat (phosphoribosyl pyrophosphate amidotransferase) Chinchilla lanigera
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Symbol: Ppat
Name: phosphoribosyl pyrophosphate amidotransferase
RGD ID: 8843586
Description: ENCODES a protein that exhibits amidophosphoribosyltransferase activity (ortholog); identical protein binding (ortholog); INVOLVED IN 'de novo' AMP biosynthetic process (ortholog); 'de novo' IMP biosynthetic process (ortholog); 'de novo' XMP biosynthetic process (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; ASSOCIATED WITH congenital disorder of glycosylation type IIk (ortholog); Experimental Diabetes Mellitus (ortholog); Experimental Liver Neoplasms (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amidophosphoribosyltransferase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544714,574,407 - 14,607,416 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544714,552,846 - 14,607,416 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544714,574,407 - 14,607,416 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544714,552,846 - 14,607,416 (+)NCBIChiLan1.0ChiLan1.0
PPAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38456,393,362 - 56,435,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl456,393,362 - 56,435,615 (-)EnsemblGRCh38hg38GRCh38
GRCh37457,259,528 - 57,301,781 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36456,954,285 - 56,996,602 (-)NCBINCBI36Build 36hg18NCBI36
Build 34457,100,458 - 57,142,773NCBI
Celera454,765,911 - 54,808,216 (-)NCBICelera
Cytogenetic Map4q12NCBI
HuRef453,213,663 - 53,255,937 (-)NCBIHuRef
CHM1_1457,294,641 - 57,336,915 (-)NCBICHM1_1
T2T-CHM13v2.0459,881,364 - 59,923,605 (-)NCBIT2T-CHM13v2.0
Ppat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39577,061,096 - 77,099,425 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl577,061,096 - 77,099,425 (-)EnsemblGRCm39 Ensembl
GRCm38576,913,249 - 76,951,578 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl576,913,249 - 76,951,578 (-)EnsemblGRCm38mm10GRCm38
MGSCv37577,342,274 - 77,380,603 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36577,987,920 - 78,026,353 (-)NCBIMGSCv36mm8
Celera574,190,125 - 74,219,445 (-)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map541.45NCBI
Ppat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81431,570,010 - 31,604,410 (+)NCBIGRCr8
mRatBN7.21431,215,741 - 31,250,144 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1431,216,165 - 31,250,144 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1431,593,072 - 31,627,368 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01432,901,403 - 32,935,708 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01431,386,077 - 31,420,375 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01433,580,541 - 33,614,919 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1433,580,541 - 33,614,919 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01433,371,454 - 33,405,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41433,509,364 - 33,543,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11433,509,363 - 33,543,743 (+)NCBI
Celera1430,529,492 - 30,563,868 (+)NCBICelera
Cytogenetic Map14p11NCBI
PPAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2373,347,602 - 73,390,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1473,553,280 - 73,595,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0467,491,407 - 67,533,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1474,059,967 - 74,102,002 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl474,059,966 - 74,102,002 (+)Ensemblpanpan1.1panPan2
PPAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11348,618,460 - 48,656,164 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1348,620,714 - 48,655,780 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1348,509,175 - 48,546,691 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01349,233,071 - 49,270,374 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1349,207,789 - 49,270,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11348,904,984 - 48,942,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01348,433,951 - 48,471,441 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01349,380,077 - 49,417,387 (-)NCBIUU_Cfam_GSD_1.0
Ppat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528527,649,519 - 27,693,748 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648218,606,124 - 18,648,681 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648218,606,124 - 18,648,989 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl855,654,377 - 55,701,077 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1855,652,194 - 55,701,077 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2857,820,418 - 57,896,880 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1712,201,434 - 12,242,418 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl712,191,784 - 12,243,488 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606612,869,154 - 12,912,322 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476112,980,513 - 13,019,011 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476112,980,508 - 13,017,818 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000006075   ⟹   ENSCLAP00000005972
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544714,574,407 - 14,607,416 (+)Ensembl
RefSeq Acc Id: XM_005392870   ⟹   XP_005392927
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544714,574,562 - 14,607,416 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005392871   ⟹   XP_005392928
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544714,581,556 - 14,607,416 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013518498   ⟹   XP_013373952
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544714,572,356 - 14,607,416 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013518499   ⟹   XP_013373953
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544714,552,846 - 14,607,416 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005392927 (Get FASTA)   NCBI Sequence Viewer  
  XP_005392928 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373952 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373953 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005972
  ENSCLAP00000005972.1
RefSeq Acc Id: XP_005392927   ⟸   XM_005392870
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UUF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005392928   ⟸   XM_005392871
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013373953   ⟸   XM_013518499
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013373952   ⟸   XM_013518498
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000005972   ⟸   ENSCLAT00000006075

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004229 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006075 ENTREZGENE
  ENSCLAT00000006075.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2020 UniProtKB/TrEMBL
  3.60.20.10 UniProtKB/TrEMBL
InterPro GATase_2_dom UniProtKB/TrEMBL
  Ntn_hydrolases_N UniProtKB/TrEMBL
  PRibTrfase_dom UniProtKB/TrEMBL
  PRTase-like UniProtKB/TrEMBL
  PurF UniProtKB/TrEMBL
  PurF_N UniProtKB/TrEMBL
NCBI Gene Ppat ENTREZGENE
PANTHER AMIDOPHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  AMIDOPHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
Pfam GATase_6 UniProtKB/TrEMBL
PIRSF Amd_phspho_trans UniProtKB/TrEMBL
PROSITE GATASE_TYPE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53271 UniProtKB/TrEMBL
  SSF56235 UniProtKB/TrEMBL
UniProt A0A8C2UUF7 ENTREZGENE, UniProtKB/TrEMBL