Anpep (alanyl aminopeptidase, membrane) - Rat Genome Database

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Gene: Anpep (alanyl aminopeptidase, membrane) Chinchilla lanigera
Analyze
Symbol: Anpep
Name: alanyl aminopeptidase, membrane
RGD ID: 8843491
Description: ENCODES a protein that exhibits aminopeptidase activity (ortholog); peptide binding (ortholog); INVOLVED IN metanephric proximal tubule development (ortholog); peptide catabolic process (ortholog); protein processing (ortholog); PARTICIPATES IN angiotensin IV signaling pathway; glutathione metabolic pathway; glutathione synthase deficiency pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); D-2-hydroxyglutaric aciduria 2 (ortholog); FOUND IN brush border membrane (ortholog); endoplasmic reticulum-Golgi intermediate compartment (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alanyl (membrane) aminopeptidase; aminopeptidase N
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,424,932 - 15,444,075 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,415,981 - 15,442,032 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Anpep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,424,932 - 15,444,075 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,415,981 - 15,442,032 (+)NCBIChiLan1.0ChiLan1.0
ANPEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,784,895 - 89,814,852 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,784,895 - 89,815,401 (-)EnsemblGRCh38hg38GRCh38
GRCh371590,328,126 - 90,358,084 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,129,130 - 88,159,076 (-)NCBINCBI36Build 36hg18NCBI36
Build 341588,129,130 - 88,150,938NCBI
Celera1566,730,914 - 66,760,859 (-)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1566,440,812 - 66,470,613 (-)NCBIHuRef
CHM1_11590,169,132 - 90,199,097 (-)NCBICHM1_1
T2T-CHM13v2.01587,540,783 - 87,570,713 (-)NCBIT2T-CHM13v2.0
Anpep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,471,551 - 79,497,958 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,471,551 - 79,510,807 (-)EnsemblGRCm39 Ensembl
GRCm38779,821,803 - 79,848,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,821,803 - 79,861,059 (-)EnsemblGRCm38mm10GRCm38
MGSCv37786,966,689 - 86,987,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,695,316 - 79,715,797 (-)NCBIMGSCv36mm8
Celera777,221,100 - 77,243,027 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.19NCBI
Anpep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,176,645 - 143,219,447 (-)NCBIGRCr8
mRatBN7.21133,767,332 - 133,810,137 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,767,332 - 133,785,789 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,676,519 - 141,695,002 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,845,924 - 148,864,407 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,763,630 - 141,782,111 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01141,561,364 - 141,604,249 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,561,334 - 141,604,273 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,522,426 - 142,565,721 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,600,751 - 135,619,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,679,156 - 135,697,614 (-)NCBI
Celera1125,830,648 - 125,849,086 (-)NCBICelera
RH 3.4 Map11063.2RGD
Cytogenetic Map1q31NCBI
ANPEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21679,335,577 - 79,365,554 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11583,037,936 - 83,059,833 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01568,479,349 - 68,509,238 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,681,826 - 87,703,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1587,681,826 - 87,703,713 (-)Ensemblpanpan1.1panPan2
ANPEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,764,418 - 52,779,516 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,764,418 - 52,779,746 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,398,319 - 55,413,377 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,181,131 - 53,196,208 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,181,130 - 53,203,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,702,917 - 52,717,931 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,912,916 - 52,927,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,253,252 - 53,268,352 (-)NCBIUU_Cfam_GSD_1.0
Anpep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,745,212 - 130,770,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,563,528 - 15,589,601 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,563,540 - 15,582,521 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANPEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,351,087 - 55,373,881 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1755,351,081 - 55,373,856 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,240,144 - 60,262,909 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7cen-q21NCBI
ANPEP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1298,324,094 - 8,354,491 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl298,323,797 - 8,346,581 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605938,429,007 - 38,487,801 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anpep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,838,693 - 16,856,059 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,840,743 - 16,856,158 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022706   ⟹   ENSCLAP00000022499
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541615,424,932 - 15,444,075 (+)Ensembl
RefSeq Acc Id: XM_005381541   ⟹   XP_005381598
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541615,418,899 - 15,442,032 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005381542   ⟹   XP_005381599
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541615,418,899 - 15,442,032 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512629   ⟹   XP_013368083
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541615,415,981 - 15,442,032 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381598 (Get FASTA)   NCBI Sequence Viewer  
  XP_005381599 (Get FASTA)   NCBI Sequence Viewer  
  XP_013368083 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022499
  ENSCLAP00000022499.1
Reference Protein Sequences
RefSeq Acc Id: XP_005381598   ⟸   XM_005381541
- UniProtKB: A0A8C2W312 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005381599   ⟸   XM_005381542
- UniProtKB: A0A8C2W312 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368083   ⟸   XM_013512629
- UniProtKB: A0A8C2W312 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022499   ⟸   ENSCLAT00000022706
Protein Domains
Aminopeptidase N-like N-terminal   ERAP1-like C-terminal   Peptidase M1 membrane alanine aminopeptidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022706 ENTREZGENE
  ENSCLAT00000022706.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.390.10 UniProtKB/TrEMBL
  1.25.50.20 UniProtKB/TrEMBL
  2.60.40.1730 UniProtKB/TrEMBL
  2.60.40.1910 UniProtKB/TrEMBL
InterPro Aminopeptidase_N-like_N UniProtKB/TrEMBL
  Aminopeptidase_N-like_N_sf UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/TrEMBL
  Peptidase_M4/M1_CTD_sf UniProtKB/TrEMBL
NCBI Gene Anpep ENTREZGENE
PANTHER AMINOPEPTIDASE N UniProtKB/TrEMBL
  PROTEASE M1 ZINC METALLOPROTEASE UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/TrEMBL
  Peptidase_M1_N UniProtKB/TrEMBL
PRINTS ALADIPTASE UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF63737 UniProtKB/TrEMBL
UniProt A0A8C2W312 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Anpep  alanyl aminopeptidase, membrane    alanyl (membrane) aminopeptidase  Symbol and/or name change 5135510 APPROVED