Grap2 (GRB2 related adaptor protein 2) - Rat Genome Database

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Gene: Grap2 (GRB2 related adaptor protein 2) Chinchilla lanigera
Analyze
Symbol: Grap2
Name: GRB2 related adaptor protein 2
RGD ID: 8842927
Description: ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Anaphylaxis (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GRB2-related adapter protein 2; GRB2-related adaptor protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,691,439 - 25,758,813 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,691,824 - 25,758,461 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
endosome  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)
plasma membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Grap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,691,439 - 25,758,813 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,691,824 - 25,758,461 (+)NCBIChiLan1.0ChiLan1.0
GRAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,893,820 - 39,973,721 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,901,084 - 39,973,721 (+)EnsemblGRCh38hg38GRCh38
GRCh372240,297,088 - 40,369,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,627,032 - 38,697,330 (+)NCBINCBI36Build 36hg18NCBI36
Build 342238,621,585 - 38,691,884NCBI
Celera2224,099,151 - 24,169,444 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2223,260,094 - 23,330,327 (+)NCBIHuRef
CHM1_12240,256,126 - 40,326,591 (+)NCBICHM1_1
T2T-CHM13v2.02240,364,806 - 40,444,710 (+)NCBIT2T-CHM13v2.0
Grap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,456,798 - 80,537,055 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,456,795 - 80,537,055 (+)EnsemblGRCm39 Ensembl
GRCm381580,572,597 - 80,652,854 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,572,594 - 80,652,854 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,453,913 - 80,480,728 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,450,738 - 80,477,553 (+)NCBIMGSCv36mm8
Celera1582,743,068 - 82,770,161 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.88NCBI
Grap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,997,356 - 114,071,073 (+)NCBIGRCr8
mRatBN7.27112,117,142 - 112,190,880 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,117,142 - 112,190,877 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,872,662 - 113,946,895 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,096,186 - 116,170,437 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,065,563 - 116,139,810 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,791,330 - 121,864,835 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,841,855 - 121,864,679 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,781,461 - 121,854,021 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,856,130 - 118,931,148 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,882,484 - 118,965,381 (+)NCBI
Celera7108,442,874 - 108,515,048 (+)NCBICelera
Cytogenetic Map7q34NCBI
GRAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,740,213 - 49,826,205 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,431,531 - 52,517,497 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,831,191 - 20,878,867 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,651,719 - 38,696,566 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,651,719 - 38,696,566 (+)Ensemblpanpan1.1panPan2
GRAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,156,233 - 25,220,106 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,157,841 - 25,220,222 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,092,401 - 25,156,329 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,908,310 - 25,972,290 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,909,919 - 25,972,202 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,619,908 - 25,683,843 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,942,524 - 26,006,115 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,117,033 - 26,181,059 (-)NCBIUU_Cfam_GSD_1.0
Grap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,745,057 - 8,816,596 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,759,298 - 1,796,049 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,759,182 - 1,796,049 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl58,375,762 - 8,445,068 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.158,372,920 - 8,445,128 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.255,668,663 - 5,744,087 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,478,744 - 22,548,829 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,524,851 - 22,552,977 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,050,792 - 103,121,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,458,292 - 8,476,256 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,453,946 - 8,476,256 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000024633   ⟹   ENSCLAP00000024398
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541325,691,439 - 25,758,813 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000024634   ⟹   ENSCLAP00000024399
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541325,691,439 - 25,758,813 (+)Ensembl
RefSeq Acc Id: XM_005379302   ⟹   XP_005379359
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,691,824 - 25,758,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005379304   ⟹   XP_005379361
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,691,824 - 25,758,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511605   ⟹   XP_013367059
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,716,239 - 25,758,461 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511606   ⟹   XP_013367060
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,735,150 - 25,758,461 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005379361   ⟸   XM_005379304
- UniProtKB: A0A8C2W7P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005379359   ⟸   XM_005379302
- UniProtKB: A0A8C2W7P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367059   ⟸   XM_013511605
- UniProtKB: A0A8C2W7P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367060   ⟸   XM_013511606
- UniProtKB: A0A8C2W7P1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000024398   ⟸   ENSCLAT00000024633
RefSeq Acc Id: ENSCLAP00000024399   ⟸   ENSCLAT00000024634
Protein Domains
SH2   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016753 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024633 ENTREZGENE
  ENSCLAT00000024633.1 UniProtKB/TrEMBL
  ENSCLAT00000024634 ENTREZGENE
  ENSCLAT00000024634.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro GRAP2_C_SH3 UniProtKB/TrEMBL
  Grb2-like UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Grap2 ENTREZGENE
PANTHER GRB2-RELATED ADAPTER PROTEIN 2 UniProtKB/TrEMBL
  PTHR46037 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C2W7P1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-13 Grap2  GRB2 related adaptor protein 2    GRB2-related adaptor protein 2  Symbol and/or name change 5135510 APPROVED