Lin7b (lin-7 homolog B, crumbs cell polarity complex component) - Rat Genome Database

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Gene: Lin7b (lin-7 homolog B, crumbs cell polarity complex component) Chinchilla lanigera
Analyze
Symbol: Lin7b
Name: lin-7 homolog B, crumbs cell polarity complex component
RGD ID: 8842626
Description: ENCODES a protein that exhibits PDZ domain binding (ortholog); protein domain specific binding (ortholog); protein kinase binding (ortholog); INVOLVED IN neurotransmitter secretion (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); genetic disease (ortholog); progressive familial heart block type IB (ortholog); FOUND IN cell-cell junction (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lin-7 homolog B (C. elegans)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,611,004 - 1,614,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,610,924 - 1,613,736 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Lin7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,611,004 - 1,614,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,610,924 - 1,613,736 (-)NCBIChiLan1.0ChiLan1.0
LIN7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,114,370 - 49,118,460 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,114,324 - 49,118,460 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,617,627 - 49,621,717 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,309,430 - 54,313,529 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,309,429 - 54,313,529NCBI
Celera1946,484,840 - 46,488,937 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,993,785 - 45,997,881 (+)NCBIHuRef
CHM1_11949,619,736 - 49,623,829 (+)NCBICHM1_1
T2T-CHM13v2.01952,109,104 - 52,113,194 (+)NCBIT2T-CHM13v2.0
Lin7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,017,315 - 45,019,988 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,017,315 - 45,020,007 (-)EnsemblGRCm39 Ensembl
GRCm38745,367,891 - 45,370,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,367,891 - 45,370,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,623,261 - 52,625,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,235,933 - 45,238,606 (-)NCBIMGSCv36mm8
Celera740,823,918 - 40,826,591 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.28NCBI
Lin7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,983,368 - 104,986,795 (-)NCBIGRCr8
mRatBN7.2195,846,888 - 95,849,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,846,243 - 95,849,977 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,232,405 - 101,234,980 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,705,082 - 109,707,657 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,995,482 - 102,998,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,358,313 - 101,361,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,358,396 - 101,360,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,421,965 - 102,425,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,838,781 - 95,841,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,916,891 - 95,919,467 (-)NCBI
Celera190,103,272 - 90,105,847 (-)NCBICelera
Cytogenetic Map1q22NCBI
LIN7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,228,966 - 55,233,355 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,148,666 - 57,152,856 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,125,272 - 46,129,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,045,557 - 55,055,761 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,047,704 - 55,055,761 (+)Ensemblpanpan1.1panPan2
LIN7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,332,623 - 107,336,099 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,332,623 - 107,336,302 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,332,623 - 107,336,302 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,857,485 - 107,860,971 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,857,485 - 107,861,164 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,525,392 - 107,528,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,171,615 - 107,175,101 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,007,220 - 108,010,706 (-)NCBIUU_Cfam_GSD_1.0
Lin7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,441,132 - 21,444,484 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,059,359 - 3,062,707 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,059,365 - 3,062,674 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,309,535 - 54,313,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,309,552 - 54,313,138 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,015,309 - 50,018,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIN7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,337,437 - 42,341,865 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,337,806 - 42,342,128 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,230,042 - 22,234,175 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lin7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,965,537 - 4,968,516 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,965,537 - 4,968,574 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000010948   ⟹   ENSCLAP00000010815
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555591,611,004 - 1,614,320 (-)Ensembl
RefSeq Acc Id: XM_013509002   ⟹   XP_013364456
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,610,924 - 1,613,736 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509003   ⟹   XP_013364457
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,610,924 - 1,613,618 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013364456 (Get FASTA)   NCBI Sequence Viewer  
  XP_013364457 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010815
  ENSCLAP00000010815.1
Reference Protein Sequences
RefSeq Acc Id: XP_013364456   ⟸   XM_013509002
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013364457   ⟸   XM_013509003
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000010815   ⟸   ENSCLAT00000010948
Protein Domains
L27   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007463 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010948 ENTREZGENE
  ENSCLAT00000010948.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  L27 domain UniProtKB/TrEMBL
InterPro L27_C UniProtKB/TrEMBL
  L27_dom UniProtKB/TrEMBL
  L27_dom_sf UniProtKB/TrEMBL
  LIN7 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene Lin7b ENTREZGENE
PANTHER PROTEIN LIN-7 HOMOLOG UniProtKB/TrEMBL
  PROTEIN LIN-7 HOMOLOG B UniProtKB/TrEMBL
Pfam L27 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PIRSF Lin-7_homologue UniProtKB/TrEMBL
PROSITE L27 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART L27 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF101288 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A8C2VCR1_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Lin7b  lin-7 homolog B, crumbs cell polarity complex component    lin-7 homolog B (C. elegans)  Symbol and/or name change 5135510 APPROVED