Sdhb (succinate dehydrogenase complex iron sulfur subunit B) - Rat Genome Database

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Gene: Sdhb (succinate dehydrogenase complex iron sulfur subunit B) Chinchilla lanigera
Analyze
Symbol: Sdhb
Name: succinate dehydrogenase complex iron sulfur subunit B
RGD ID: 8841157
Description: ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (ortholog); 3 iron, 4 sulfur cluster binding (ortholog); 4 iron, 4 sulfur cluster binding (ortholog); INVOLVED IN respiratory electron transport chain (ortholog); succinate metabolic process (ortholog); PARTICIPATES IN altered citric acid cycle pathway; citric acid cycle pathway; electron transport chain pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); Bannayan-Riley-Ruvalcaba syndrome (ortholog); bilateral breast cancer (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,768,940 - 1,792,361 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,769,280 - 1,792,496 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Sdhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,768,940 - 1,792,361 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,769,280 - 1,792,496 (+)NCBIChiLan1.0ChiLan1.0
SDHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,018,722 - 17,054,032 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,018,664 - 17,054,032 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,345,217 - 17,380,527 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,217,804 - 17,253,252 (-)NCBINCBI36Build 36hg18NCBI36
Build 34117,090,558 - 17,125,952NCBI
Celera115,667,559 - 15,703,013 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,589,311 - 15,624,677 (-)NCBIHuRef
CHM1_1117,453,561 - 17,489,010 (-)NCBICHM1_1
T2T-CHM13v2.0116,829,151 - 16,864,469 (-)NCBIT2T-CHM13v2.0
Sdhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,688,582 - 140,706,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,688,514 - 140,706,504 (+)EnsemblGRCm39 Ensembl
GRCm384140,961,271 - 140,979,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,961,203 - 140,979,193 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,517,186 - 140,535,108 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,233,347 - 140,251,269 (+)NCBIMGSCv36mm8
Celera4142,761,706 - 142,779,666 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.24NCBI
Sdhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,547,775 - 158,568,589 (+)NCBIGRCr8
mRatBN7.25153,264,906 - 153,285,570 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,264,899 - 153,314,293 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,953,279 - 155,973,810 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,726,549 - 157,747,081 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,715,729 - 157,736,265 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,484,378 - 159,505,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,484,370 - 159,505,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,197,045 - 163,217,315 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,818,669 - 159,839,772 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,828,844 - 159,849,873 (+)NCBI
Celera5151,629,862 - 151,650,475 (+)NCBICelera
Cytogenetic Map5q36NCBI
SDHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,076,010 - 210,111,744 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,194,917 - 209,230,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,962,383 - 15,998,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,018,531 - 17,054,509 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,018,542 - 17,054,509 (-)Ensemblpanpan1.1panPan2
SDHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,158,291 - 81,190,110 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,158,291 - 81,190,109 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,695,312 - 77,727,188 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,804,258 - 81,836,607 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,804,258 - 81,836,606 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,557,290 - 78,589,612 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,574,320 - 79,606,173 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,642,748 - 80,674,635 (+)NCBIUU_Cfam_GSD_1.0
Sdhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,168,442 - 38,196,545 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,990,778 - 4,021,423 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,993,224 - 4,021,359 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SDHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,648,215 - 75,678,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,648,362 - 75,678,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,991,035 - 70,021,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SDHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,537,880 - 115,571,150 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,538,026 - 115,571,142 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033549,592 - 583,182 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sdhb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,650,604 - 2,679,005 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,655,138 - 2,679,138 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000003552   ⟹   ENSCLAP00000003481
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555271,768,940 - 1,792,361 (+)Ensembl
RefSeq Acc Id: XM_005409822   ⟹   XP_005409879
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555271,769,280 - 1,792,496 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409879 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003481
  ENSCLAP00000003481.1
Reference Protein Sequences
RefSeq Acc Id: XP_005409879   ⟸   XM_005409822
- UniProtKB: A0A8C2UUU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000003481   ⟸   ENSCLAT00000003552
Protein Domains
2Fe-2S ferredoxin-type   4Fe-4S ferredoxin-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002488 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003552 ENTREZGENE
  ENSCLAT00000003552.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1060.10 UniProtKB/TrEMBL
  3.10.20.30 UniProtKB/TrEMBL
InterPro 2Fe-2S_ferredoxin-like_sf UniProtKB/TrEMBL
  2Fe-2S_ferredoxin-type UniProtKB/TrEMBL
  2Fe2S_fd_BS UniProtKB/TrEMBL
  4Fe4S_Fe-S-bd UniProtKB/TrEMBL
  4Fe4S_Fe_S_CS UniProtKB/TrEMBL
  Beta-grasp_dom_sf UniProtKB/TrEMBL
  Helical_ferredxn UniProtKB/TrEMBL
  Succ_DH/fum_Rdtase_Fe-S UniProtKB/TrEMBL
  Succ_DH/fum_Rdtase_N UniProtKB/TrEMBL
NCBI Gene Sdhb ENTREZGENE
PANTHER SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL UniProtKB/TrEMBL
  SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN UniProtKB/TrEMBL
Pfam Fer2_3 UniProtKB/TrEMBL
  Fer4_17 UniProtKB/TrEMBL
PROSITE 2FE2S_FER_1 UniProtKB/TrEMBL
  2FE2S_FER_2 UniProtKB/TrEMBL
  4FE4S_FER_1 UniProtKB/TrEMBL
  4FE4S_FER_2 UniProtKB/TrEMBL
Superfamily-SCOP alpha-helical ferredoxin UniProtKB/TrEMBL
  SSF54292 UniProtKB/TrEMBL
UniProt A0A8C2UUU5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Sdhb  succinate dehydrogenase complex iron sulfur subunit B    succinate dehydrogenase complex, subunit B, iron sulfur (Ip)  Symbol and/or name change 5135510 APPROVED